DK245888D0 - 4-aminoquinolinderivater - Google Patents

4-aminoquinolinderivater

Info

Publication number
DK245888D0
DK245888D0 DK245888A DK245888A DK245888D0 DK 245888 D0 DK245888 D0 DK 245888D0 DK 245888 A DK245888 A DK 245888A DK 245888 A DK245888 A DK 245888A DK 245888 D0 DK245888 D0 DK 245888D0
Authority
DK
Denmark
Prior art keywords
6alkyl
phenyl
6alkanoyl
phenylc1
6alkylthio
Prior art date
Application number
DK245888A
Other languages
English (en)
Other versions
DK159308B (da
DK245888A (da
DK159308C (da
Inventor
Thomas Henry Brown
Robert John Ife
Colin Andrew Leach
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of DK245888D0 publication Critical patent/DK245888D0/da
Publication of DK245888A publication Critical patent/DK245888A/da
Publication of DK159308B publication Critical patent/DK159308B/da
Application granted granted Critical
Publication of DK159308C publication Critical patent/DK159308C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4
    • C07D215/44Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
DK245888A 1986-09-05 1988-05-05 4-aminoquinolinderivater, farmaceutisk middel der indeholder disse samt anvendelse af disse til fremstilling af et laegemiddel DK159308C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB868621425A GB8621425D0 (en) 1986-09-05 1986-09-05 Compounds
GB8621425 1986-09-05
PCT/GB1987/000624 WO1988001621A1 (en) 1986-09-05 1987-09-04 4-aminoquinoline derivatives and their use as medicaments
GB8700624 1987-09-04

Publications (4)

Publication Number Publication Date
DK245888D0 true DK245888D0 (da) 1988-05-05
DK245888A DK245888A (da) 1988-05-05
DK159308B DK159308B (da) 1990-10-01
DK159308C DK159308C (da) 1991-03-11

Family

ID=10603729

Family Applications (1)

Application Number Title Priority Date Filing Date
DK245888A DK159308C (da) 1986-09-05 1988-05-05 4-aminoquinolinderivater, farmaceutisk middel der indeholder disse samt anvendelse af disse til fremstilling af et laegemiddel

Country Status (28)

Country Link
US (2) US4806549A (da)
EP (1) EP0259174B1 (da)
JP (1) JPH07602B2 (da)
KR (1) KR950013850B1 (da)
CN (1) CN1019802B (da)
AT (1) ATE73776T1 (da)
AU (1) AU598299B2 (da)
CA (1) CA1308106C (da)
CZ (1) CZ398291A3 (da)
DE (1) DE3777505D1 (da)
DK (1) DK159308C (da)
EG (1) EG18408A (da)
ES (1) ES2033316T3 (da)
FI (1) FI88919C (da)
GB (1) GB8621425D0 (da)
GR (1) GR3004692T3 (da)
HU (1) HU199804B (da)
IE (1) IE61104B1 (da)
IL (1) IL83691A (da)
MX (1) MX9203550A (da)
MY (1) MY102689A (da)
NO (1) NO172388C (da)
NZ (1) NZ221663A (da)
PH (1) PH23695A (da)
PT (1) PT85651B (da)
WO (1) WO1988001621A1 (da)
ZA (1) ZA876581B (da)
ZW (1) ZW16787A1 (da)

Families Citing this family (43)

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GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5049567A (en) * 1988-02-25 1991-09-17 Smithkline Beckman Intercredit B.V. Substituted 4-aminoquinazoline derivatives and method of use
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
DK273689A (da) * 1988-06-06 1989-12-07 Sanofi Sa 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
FR2632305B1 (fr) * 1988-06-06 1992-05-15 Sanofi Sa Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
EP0480052B1 (en) * 1990-03-28 1998-01-14 Otsuka Pharmaceutical Co., Ltd. Quinoline derivative, antiulcer drug containing the same, and production of said derivative
GB9126438D0 (en) * 1991-12-12 1992-02-12 Smithkline Beecham Intercredit New quinoline derivatives
US5493027A (en) * 1993-01-22 1996-02-20 Board Of Regents, The University Of Texas System Anticonvulsive agents and uses thereof
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
SE9302005D0 (sv) 1993-06-11 1993-06-11 Ab Astra New active compounds
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
IN188411B (da) * 1997-03-27 2002-09-21 Yuhan Corp
US6852739B1 (en) * 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
GB2396815B (en) * 1999-10-27 2004-09-08 Phytopharm Plc A composition comprising a pregnenone derivative and an NSAID
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
WO2003043614A2 (en) * 2001-11-19 2003-05-30 Altana Pharma Ag Reversible proton pump inhibitors for the treatment of airway disorders
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
CA2484272A1 (en) * 2002-05-07 2003-11-20 Altana Pharma Ag New combination of reversible proton pump inhibitors and airway therapeutics for treating airway disorders
US7211590B2 (en) * 2002-08-01 2007-05-01 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
RS52908B (en) 2003-03-10 2014-02-28 Takeda Gmbh NEW PROCEDURE FOR OBTAINING ROFLUMILAST
US20080280944A1 (en) 2003-11-03 2008-11-13 Paula Fernstrom Imidazo[1,2-A]Pyridine Derivatives For The Treatment Of Silent Gastro-Esophageal Reflux
SE0400284D0 (sv) * 2004-02-10 2004-02-10 Astrazeneca Ab Novel compounds
WO2006097456A1 (en) * 2005-03-16 2006-09-21 Nycomed Gmbh Taste masked dosage form containing roflumilast
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
PL2046334T3 (pl) 2006-07-25 2015-02-27 Vecta Ltd Kompozycje i sposoby hamowania wydzielania kwasów żołądkowych z wykorzystaniem pochodnych małych kwasów dikarboksylowych w połączeniu z PPI
MX2009004475A (es) 2006-10-27 2009-08-12 Univ Missouri Composiciones que comprenden agentes acido labiles que inhiben la bomba de protones, por lo menos otro agente farmaceuticamente activo y metodos de uso de las misma.
TW200829555A (en) * 2006-11-10 2008-07-16 Astrazeneca Ab Chemical compounds
CL2008000191A1 (es) * 2007-01-25 2008-08-22 Astrazeneca Ab Compuestos derivados de 4-amino-cinnotina-3-carboxamida; inhibidores de csf-1r quinasa; su proceso de preparacion; y su uso para tratar el cancer.
CA2716367C (en) 2008-02-20 2015-05-26 The Curators Of The University Of Missouri Composition comprising a combination of omeprazole and lansoprazole, and a buffering agent, and methods of using same
CN102089286A (zh) * 2008-05-07 2011-06-08 阿斯利康(瑞典)有限公司 化合物
US8247280B2 (en) 2009-10-20 2012-08-21 Taiwan Semiconductor Manufacturing Company, Ltd. Integration of low and high voltage CMOS devices
US20210177827A1 (en) * 2017-10-25 2021-06-17 Children`S Medical Center Corporation Papd5 inhibitors and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4343804A (en) * 1979-03-26 1982-08-10 A. H. Robins Company, Inc. 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds
JO1406B1 (en) * 1984-11-02 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Chemical compounds
PH22302A (en) * 1985-02-11 1988-07-22 Fujisawa Pharmaceutical Co Piperidine compounds
EP0193329A3 (en) * 1985-02-22 1987-08-19 Beecham Group Plc Pyrazolopyridines, their preparation and pharmaceutical compositions containing them
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds

Also Published As

Publication number Publication date
PT85651B (pt) 1990-05-31
GB8621425D0 (en) 1986-10-15
CA1308106C (en) 1992-09-29
EG18408A (en) 1993-02-28
HUT47913A (en) 1989-04-28
CZ398291A3 (en) 1994-02-16
AU598299B2 (en) 1990-06-21
EP0259174B1 (en) 1992-03-18
HU199804B (en) 1990-03-28
US4806549A (en) 1989-02-21
DE3777505D1 (de) 1992-04-23
DK159308B (da) 1990-10-01
ES2033316T3 (es) 1993-03-16
US4806550A (en) 1989-02-21
NO172388C (no) 1993-07-14
IL83691A (en) 1993-08-18
PH23695A (en) 1989-09-27
MX9203550A (es) 1992-09-01
ZA876581B (en) 1989-04-26
PT85651A (en) 1987-10-01
CN87106163A (zh) 1988-03-16
CN1019802B (zh) 1992-12-30
KR880701711A (ko) 1988-11-04
JPH01500664A (ja) 1989-03-09
GR3004692T3 (da) 1993-04-28
IE61104B1 (en) 1994-10-05
NZ221663A (en) 1989-08-29
ATE73776T1 (de) 1992-04-15
ZW16787A1 (en) 1988-05-25
DK245888A (da) 1988-05-05
MY102689A (en) 1992-09-30
DK159308C (da) 1991-03-11
IE872370L (en) 1988-03-05
FI882089A0 (fi) 1988-05-04
NO881940D0 (no) 1988-05-04
FI88919C (fi) 1993-07-26
FI88919B (fi) 1993-04-15
EP0259174A1 (en) 1988-03-09
KR950013850B1 (ko) 1995-11-17
NO881940L (no) 1988-05-04
FI882089A (fi) 1988-05-04
WO1988001621A1 (en) 1988-03-10
JPH07602B2 (ja) 1995-01-11
NO172388B (no) 1993-04-05
AU7874187A (en) 1988-03-24

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Legal Events

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PBP Patent lapsed