IN188411B - - Google Patents

Info

Publication number
IN188411B
IN188411B IN724DE1998A IN188411B IN 188411 B IN188411 B IN 188411B IN 724DE1998 A IN724DE1998 A IN 724DE1998A IN 188411 B IN188411 B IN 188411B
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Wook Lee-Korea Jong
Young Lee-Korea Bong
Seop Kim-Korea Chang
Kyu Lee-Korea Seung
Seog Song-Korea Keun
Jin Lee-Korea Song
Jeon Shim-Korea Woo
Soon Hwang-Korea Man
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of IN188411B publication Critical patent/IN188411B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IN724DE1998 1997-03-27 1998-03-23 IN188411B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR19970010863 1997-03-27
KR19970010862 1997-03-27

Publications (1)

Publication Number Publication Date
IN188411B true IN188411B (da) 2002-09-21

Family

ID=26632616

Family Applications (1)

Application Number Title Priority Date Filing Date
IN724DE1998 IN188411B (da) 1997-03-27 1998-03-23

Country Status (22)

Country Link
US (1) US6352993B1 (da)
EP (1) EP1015444B1 (da)
JP (1) JP3176379B2 (da)
KR (1) KR100278857B1 (da)
CN (1) CN1118464C (da)
AR (1) AR012181A1 (da)
AT (1) ATE241613T1 (da)
AU (1) AU720385B2 (da)
BR (1) BR9808070A (da)
CA (1) CA2284795C (da)
DE (1) DE69815126T2 (da)
DK (1) DK1015444T3 (da)
ES (1) ES2200324T3 (da)
HK (1) HK1026418A1 (da)
HU (1) HUP0000851A3 (da)
IN (1) IN188411B (da)
PT (1) PT1015444E (da)
RU (1) RU2203894C2 (da)
TR (1) TR199902383T2 (da)
TW (1) TW542831B (da)
UY (1) UY24938A1 (da)
WO (1) WO1998043968A1 (da)

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KR100272471B1 (ko) 1998-11-17 2000-11-15 김선진 신규의 피리미딘 유도체 및 그의 제조방법
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
TW200302728A (en) 2002-02-01 2003-08-16 Novartis Ag Substituted amines as IgE inhibitors
US7211590B2 (en) 2002-08-01 2007-05-01 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
JP2006528640A (ja) * 2003-07-22 2006-12-21 ニューロジェン・コーポレーション 置換ピリジン−２−イルアミン類縁体
CA2541989C (en) * 2003-10-24 2013-10-01 Exelixis, Inc. P70s6 kinase modulators and method of use
EP1974730A1 (en) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux
KR101122376B1 (ko) * 2005-03-09 2012-03-26 주식회사유한양행 신규의 5,6-다이메틸피리미딘 유도체 및 그의 제조방법
WO2007042571A1 (en) * 2005-10-14 2007-04-19 Neurosearch A/S Novel pyrimidine-2,4-diamine derivatives and their use as modulators of small-conductance calcium-activated potassium channels
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
JP5630867B2 (ja) 2008-08-05 2014-11-26 第一三共株式会社 イミダゾピリジン−２−オン誘導体
GB0908394D0 (en) 2009-05-15 2009-06-24 Univ Leuven Kath Novel viral replication inhibitors
GB0913636D0 (en) 2009-08-05 2009-09-16 Univ Leuven Kath Novel viral replication inhibitors
EP2640705A2 (en) 2010-11-15 2013-09-25 Katholieke Universiteit Leuven Novel antiviral compounds
EP2678332B1 (en) 2011-02-25 2016-05-18 Yuhan Corporation Diaminopyrimidine derivatives and processes for the preparation thereof
WO2013123401A1 (en) * 2012-02-17 2013-08-22 Abbvie Inc. Diaminopyrimidines useful as inhibitors of the human respiratory syncytial virus (rsv)
CA2873674A1 (en) 2012-05-29 2013-12-05 Momentive Performance Materials Gmbh Preparation of isocyanato silanes
SG10201600149VA (en) 2012-11-21 2016-02-26 Ptc Therapeutics Inc Substituted reverse pyrimidine bmi-1 inhibitors
JP6660182B2 (ja) 2013-03-13 2020-03-11 ジェネンテック， インコーポレイテッド ピラゾロ化合物及びその使用
EP3039015B1 (en) 2013-08-30 2019-10-30 PTC Therapeutics, Inc. Substituted pyrimidine bmi-1 inhibitors
EP3055301B1 (en) * 2013-10-07 2019-11-20 Kadmon Corporation, LLC (2-(5-isoindolin-2-yl)pyrimidin-4-yl)-amine derivatives as rho kinase inhibitors for treating autoimmune diseases
US10584115B2 (en) 2013-11-21 2020-03-10 Ptc Therapeutics, Inc. Substituted pyridine and pyrazine BMI-1 inhibitors
US10370360B2 (en) 2014-10-22 2019-08-06 The Board Of Regents Of The University Of Texas System Small-molecule inhibitors targeting discoidin domain receptor 1 and uses thereof
CN105669642B (zh) * 2014-11-19 2020-06-09 江苏天士力帝益药业有限公司 一种盐酸洛氟普啶的制备方法
LT3397622T (lt) * 2016-01-04 2022-06-27 ObsEva S.A. Hidroksipropiltiazolidino karboksamido darinio alfa-amino esterio ir tokolitinio agento įvedimas kartu
JP7107962B2 (ja) * 2017-04-05 2022-07-27 バイエル・クロップサイエンス・アクチェンゲゼルシャフト ２－アミノ－５－オキシアルキル－ピリミジン誘導体および望ましくない植物成長を防除するためのその使用
BR112021002630A2 (pt) 2018-08-17 2021-05-11 Ptc Therapeutics, Inc. método para tratar câncer pancreático
CN114685369B (zh) * 2022-05-17 2024-02-02 河南省科学院高新技术研究中心 一种利用离子液体制备1-甲基-1,2,3,4-四氢异喹啉的方法

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US3980781A (en) 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
US4000138A (en) 1966-03-31 1976-12-28 Imperial Chemical Industries Limited Organic compounds and compositions containing them
GB1182584A (en) 1966-03-31 1970-02-25 Ici Ltd Pyrimidine derivates and the use thereof as fungicides
GB1383409A (en) 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
US4044136A (en) 1972-09-09 1977-08-23 Pfizer Inc. Aminoquinazoline therapeutic agents
US3956495A (en) 1973-10-30 1976-05-11 Eli Lilly And Company 2,4-Diaminoquinazolines as antithrombotic agents
US4755218A (en) 1985-12-31 1988-07-05 Monsanto Company Haloacyl 1-substituted-1,2,3,4-tetrahydro-isoquinolines as herbicide antidotes
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
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US4966622A (en) 1988-04-12 1990-10-30 Ciba-Geigy Corporation N-phenyl-N-pyrimidin-2-ylureas
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
DE3901448A1 (de) 1989-01-19 1990-07-26 Basf Ag Emulsionscopolymerisate
TR25912A (tr) 1989-03-22 1993-11-01 Ciba Geigy Ag 2-ANILIN-PRIMIDIN TüREVLERI BU MADDELERINELDE EDIL MELERI VE ZARARLILARA KARSI MüCADELEDE KULLANILMA- LARI
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CA2015981A1 (en) * 1989-05-10 1990-11-10 Thomas H. Brown Compounds
GB9012592D0 (en) 1990-06-06 1990-07-25 Smithkline Beecham Intercredit Compounds
KR930702292A (ko) 1990-11-06 1993-09-08 알렌 제이. 스피겔 종양 치료 활성을 증대시키기 위한 퀴나졸린 유도체
JPH0819121B2 (ja) * 1991-04-17 1996-02-28 フアイザー・インコーポレイテツド 抗腫瘍活性を増強するためのピリミジン誘導体
US5276186A (en) 1992-03-11 1994-01-04 Ciba-Geigy Corporation Process for the production of guanidine derivatives
KR0144833B1 (ko) * 1992-12-28 1998-07-15 김태훈 신규의 퀴나졸린 유도체 및 그의 제조방법
DK0640599T3 (da) 1993-08-26 1998-09-28 Ono Pharmaceutical Co 4-Aminopyrimidin-derivater
WO1995010506A1 (en) 1993-10-12 1995-04-20 The Du Pont Merck Pharmaceutical Company 1n-alkyl-n-arylpyrimidinamines and derivatives thereof
CA2197298C (en) * 1994-08-13 1999-10-19 Jong Wook Lee Novel pyrimidine derivatives and processes for the preparation thereof
CN1190427C (zh) 1996-05-04 2005-02-23 株式会社柳韩洋行 制备嘧啶衍生物的方法

Also Published As

Publication number Publication date
CA2284795C (en) 2004-01-20
US6352993B1 (en) 2002-03-05
KR19980080789A (ko) 1998-11-25
PT1015444E (pt) 2003-10-31
ATE241613T1 (de) 2003-06-15
EP1015444B1 (en) 2003-05-28
CN1118464C (zh) 2003-08-20
AU6523998A (en) 1998-10-22
CN1251586A (zh) 2000-04-26
TR199902383T2 (xx) 2000-06-21
BR9808070A (pt) 2000-03-08
HUP0000851A3 (en) 2002-04-29
JP3176379B2 (ja) 2001-06-18
ES2200324T3 (es) 2004-03-01
KR100278857B1 (ko) 2001-01-15
DE69815126T2 (de) 2004-04-08
UY24938A1 (es) 2001-01-31
HUP0000851A1 (hu) 2001-04-28
AR012181A1 (es) 2000-09-27
RU2203894C2 (ru) 2003-05-10
HK1026418A1 (en) 2000-12-15
WO1998043968A1 (en) 1998-10-08
JP2000513014A (ja) 2000-10-03
AU720385B2 (en) 2000-06-01
DK1015444T3 (da) 2003-08-18
DE69815126D1 (de) 2003-07-03
EP1015444A1 (en) 2000-07-05
CA2284795A1 (en) 1998-10-08
TW542831B (en) 2003-07-21

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