NO854723L - Bionedbrytbar matriks og fremgangsmaate for fremstilling av denne. - Google Patents

Bionedbrytbar matriks og fremgangsmaate for fremstilling av denne.

Info

Publication number
NO854723L
NO854723L NO854723A NO854723A NO854723L NO 854723 L NO854723 L NO 854723L NO 854723 A NO854723 A NO 854723A NO 854723 A NO854723 A NO 854723A NO 854723 L NO854723 L NO 854723L
Authority
NO
Norway
Prior art keywords
collagen
specified
based matrix
freeze
temperature
Prior art date
Application number
NO854723A
Other languages
English (en)
Norwegian (no)
Inventor
Frederick H Silver
Richard A Berg
David E Birk
Kevin Weadock
Conrad Whyne
Original Assignee
Univ New Jersey Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New Jersey Med filed Critical Univ New Jersey Med
Publication of NO854723L publication Critical patent/NO854723L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/425—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/64—Use of materials characterised by their function or physical properties specially adapted to be resorbable inside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0033—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23—Carbohydrates
    • A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A61L2300/254—Enzymes, proenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432—Inhibitors, antagonists
    • A61L2300/434—Inhibitors, antagonists of enzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/08—Collagen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NO854723A 1984-03-27 1985-11-26 Bionedbrytbar matriks og fremgangsmaate for fremstilling av denne. NO854723L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59373384A 1984-03-27 1984-03-27

Publications (1)

Publication Number Publication Date
NO854723L true NO854723L (no) 1985-11-26

Family

ID=24375922

Family Applications (1)

Application Number Title Priority Date Filing Date
NO854723A NO854723L (no) 1984-03-27 1985-11-26 Bionedbrytbar matriks og fremgangsmaate for fremstilling av denne.

Country Status (17)

Country Link
US (2) US4703108A (fr)
EP (1) EP0177573B1 (fr)
JP (1) JPH0811121B2 (fr)
CN (1) CN85101396A (fr)
AR (1) AR240608A1 (fr)
AU (1) AU4210585A (fr)
BR (1) BR8506206A (fr)
CA (1) CA1295796C (fr)
DE (1) DE3585069D1 (fr)
DK (1) DK547485A (fr)
ES (1) ES8605988A1 (fr)
FI (1) FI854692A0 (fr)
IL (1) IL74715A0 (fr)
IT (1) IT1182725B (fr)
MX (1) MX163953B (fr)
NO (1) NO854723L (fr)
WO (1) WO1985004413A1 (fr)

Families Citing this family (463)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837285A (en) * 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US4925924A (en) * 1984-03-27 1990-05-15 University Of Medicine And Dentistry Of New Jersey Biocompatible synthetic and collagen compositions having a dual-type porosity for treatment of wounds and pressure ulcers and therapeutic methods thereof
US4766073A (en) * 1985-02-25 1988-08-23 Zymogenetics Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US4849407A (en) * 1986-08-13 1989-07-18 Zymogenetics, Inc. Biologically active mosaic proteins
US5187263A (en) * 1984-10-12 1993-02-16 Zymogenetics, Inc. Expression of biologically active PDGE analogs in eucaryotic cells
US5498600A (en) * 1984-10-12 1996-03-12 Zymogenetics, Inc. Biologically active mosaic proteins
EP0487116B1 (fr) * 1984-10-12 1999-12-29 ZymoGenetics, Inc. Analogues biologiquement actifs d'un facteur de croissance provenant de plaquettes sanguines dans des cellules eucaryotiques
US5629191A (en) * 1985-01-03 1997-05-13 Integra Lifesciences Corporation Method of making a porous matrix particle
US5516896A (en) * 1985-02-25 1996-05-14 Zymogenetics, Inc. Biologically active B-chain homodimers
US5045633A (en) * 1985-02-25 1991-09-03 Zymogenetics, Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US4861714A (en) * 1985-04-04 1989-08-29 Verax Corporation Weighted collagen microsponge for immobilizing bioactive material
US4863856A (en) * 1985-04-04 1989-09-05 Verax Corporation Weighted collagen microsponge for immobilizing bioactive materials
US4997753A (en) * 1985-04-04 1991-03-05 Verax Corporation Weighted collagen microsponge for immobilizing bioactive material
US5628781A (en) * 1985-06-06 1997-05-13 Thomas Jefferson University Implant materials, methods of treating the surface of implants with microvascular endothelial cells, and the treated implants themselves
CA1284250C (fr) * 1985-09-06 1991-05-14 Dale P. Devore Collagene viscoelastique pour emploi ophtalmique, et sa preparation
US4713446A (en) * 1985-09-06 1987-12-15 Minnesota Mining And Manufacturing Company Viscoelastic collagen solution for ophthalmic use and method of preparation
US4851513A (en) * 1985-09-06 1989-07-25 Minnesota Mining And Manufacturing Company Viscoelastic collagen solution for opthalmic use and method of preparation
US4883864A (en) * 1985-09-06 1989-11-28 Minnesota Mining And Manufacturing Company Modified collagen compound and method of preparation
IT1181737B (it) * 1985-11-26 1987-09-30 Pierfrancesco Morganti Supproto di collagene biologicamente attivo per uso cosmetico e farmaceutico e metodo per prepararlo
US6311690B1 (en) * 1986-03-27 2001-11-06 Gensci Orthobiologics, Inc. Bone repair material and delayed drug delivery system
US5904718A (en) * 1986-03-27 1999-05-18 Biocoll Laboratories, Inc. Delayed drug delivery system
US5863531A (en) * 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US4963489A (en) * 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5032508A (en) * 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
JP2857392B2 (ja) * 1986-04-18 1999-02-17 マロウーテク インコーポレーテッド 骨髄の複製方法およびその組織の試験管内複製法とその使用法
US5510254A (en) * 1986-04-18 1996-04-23 Advanced Tissue Sciences, Inc. Three dimensional cell and tissue culture system
US5160490A (en) * 1986-04-18 1992-11-03 Marrow-Tech Incorporated Three-dimensional cell and tissue culture apparatus
IL78826A (en) * 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
WO1988001166A1 (fr) * 1986-08-18 1988-02-25 Biota Scientific Management Pty Ltd Stimulation de l'angiogenese et promotion de l'endothelialisation
IT1198449B (it) * 1986-10-13 1988-12-21 F I D I Farmaceutici Italiani Esteri di alcoli polivalenti di acido ialuronico
US5672334A (en) * 1991-01-16 1997-09-30 Access Pharmaceuticals, Inc. Invivo agents comprising cationic metal chelators with acidic saccharides and glycosaminoglycans
US5707604A (en) * 1986-11-18 1998-01-13 Access Pharmaceuticals, Inc. Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles
US5976878A (en) * 1987-04-28 1999-11-02 The Regents Of The University Of California Method and apparatus for preparing composite skin replacement
US5273900A (en) * 1987-04-28 1993-12-28 The Regents Of The University Of California Method and apparatus for preparing composite skin replacement
US4952403A (en) * 1987-06-19 1990-08-28 President And Fellows Of Harvard College Implants for the promotion of healing of meniscal tissue
JPS642643A (en) * 1987-06-26 1989-01-06 Bio Material Yunibaasu:Kk Artificial skin
US4983393A (en) * 1987-07-21 1991-01-08 Maximed Corporation Intra-vaginal device and method for sustained drug release
US5078744A (en) * 1987-09-04 1992-01-07 Bio-Products, Inc. Method of using tendon/ligament substitutes composed of long, parallel, non-antigenic tendon/ligament fibers
US6174999B1 (en) 1987-09-18 2001-01-16 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US6610669B1 (en) 1987-09-18 2003-08-26 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US5527893A (en) * 1987-09-18 1996-06-18 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
WO1989004339A1 (fr) * 1987-11-02 1989-05-18 Terumo Kabushiki Kaisha Moulages de fibroine, procede de preparation, support d'immobilisation d'heparine et procede de preparation
WO1989004172A1 (fr) * 1987-11-09 1989-05-18 Chiron Ophthalmics Inc. Procede et composition de cicatrisation de blessures
US5053388A (en) * 1987-11-09 1991-10-01 Chiron Ophthalmics, Inc. Wound healing composition and method
US5759815A (en) * 1988-02-11 1998-06-02 Creative Biomolecules, Inc. Production of platelet derived growth factor (PDGF) an muteins thereof
US5660692A (en) * 1988-02-24 1997-08-26 Cedars-Sinai Medical Center Method of crosslinking amino acid-containing polymers using photoactivatable chemical crosslinkers
US5350583A (en) * 1988-03-09 1994-09-27 Terumo Kabushiki Kaisha Cell-penetrable medical material and artificial skin
WO1989008465A1 (fr) * 1988-03-09 1989-09-21 Terumo Kabushiki Kaisha Substance medicale dans laquelle les cellules peuvent penetrer et peau artificielle
US4975526A (en) * 1989-02-23 1990-12-04 Creative Biomolecules, Inc. Bone collagen matrix for zenogenic implants
US6919308B2 (en) * 1988-04-08 2005-07-19 Stryker Corporation Osteogenic devices
US5266683A (en) 1988-04-08 1993-11-30 Stryker Corporation Osteogenic proteins
US20070166353A1 (en) * 1988-04-08 2007-07-19 Stryker Corporation Osteogenic proteins
US5354557A (en) * 1988-04-08 1994-10-11 Stryker Corporation Osteogenic devices
US6586388B2 (en) 1988-04-08 2003-07-01 Stryker Corporation Method of using recombinant osteogenic protein to repair bone or cartilage defects
US5605835A (en) * 1988-05-23 1997-02-25 Regents Of The University Of Minnesota Bioreactor device with application as a bioartificial liver
US4950483A (en) * 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US5447966A (en) * 1988-07-19 1995-09-05 United States Surgical Corporation Treating bioabsorbable surgical articles by coating with glycerine, polalkyleneoxide block copolymer and gelatin
US4948540A (en) * 1988-08-01 1990-08-14 Semex Medical, Inc. Method of preparing collagen dressing sheet material
FR2635459B1 (fr) * 1988-08-17 1992-06-19 Cird Procede de fabrication de microspheres par reticulation de proteines, microspheres ainsi obtenues et leurs utilisations
US5298243A (en) * 1988-10-20 1994-03-29 Denki Kagaku Kogyo Kabushiki Kaisha Colony stimulating factor-gelatin conjugate
US5565519A (en) * 1988-11-21 1996-10-15 Collagen Corporation Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications
US5510418A (en) * 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5819748A (en) * 1988-11-30 1998-10-13 Ed Geistlich Sohne Ag Fur Chemische Industrie Implant for use in bone surgery
US5654267A (en) * 1988-12-20 1997-08-05 La Jolla Cancer Research Center Cooperative combinations of ligands contained within a matrix
AU628910B2 (en) * 1988-12-20 1992-09-24 La Jolla Cancer Research Foundation Polypeptide-polymer conjugates active in wound healing
US5356883A (en) 1989-08-01 1994-10-18 Research Foundation Of State University Of N.Y. Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
CA1340994C (fr) * 1989-09-21 2000-05-16 Rudolf Edgar Dr. Falk Traitement de maladies et d'etats pathologiques
CS277464B6 (en) * 1989-09-26 1993-03-17 Ustav Makromolekularni Chemie Contact lens made of hydrophilic gels
DK0448704T3 (da) * 1989-10-17 1999-04-06 Stryker Corp Osteogene anordninger
DE3936568C2 (de) * 1989-11-03 1997-06-19 Karlheinz Prof Dr Dr Schmidt Wirkstoffkomplex für die Herstellung von biologischen Teilen in Form von Organen für Lebewesen; Verfahren zum Herstellen desselben und seine Verwendung
US5282859A (en) * 1990-04-24 1994-02-01 Mark Eisenberg Composite living skin equivalents
US5290271A (en) * 1990-05-14 1994-03-01 Jernberg Gary R Surgical implant and method for controlled release of chemotherapeutic agents
US5197882A (en) * 1990-05-14 1993-03-30 Gary R. Jernberg Periodontal barrier and method for aiding periodontal tissue regeneration agents
US5059123A (en) * 1990-05-14 1991-10-22 Jernberg Gary R Periodontal barrier and method for aiding periodontal tissue regeneration
US5833665A (en) * 1990-06-14 1998-11-10 Integra Lifesciences I, Ltd. Polyurethane-biopolymer composite
US5639738A (en) * 1992-02-20 1997-06-17 Hyal Pharmaceutical Corporation Treatment of basal cell carcinoma and actinic keratosis employing hyaluronic acid and NSAIDs
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
US5206028A (en) * 1991-02-11 1993-04-27 Li Shu Tung Dense collagen membrane matrices for medical uses
US5603872A (en) * 1991-02-14 1997-02-18 Baxter International Inc. Method of binding recognizing substances to liposomes
US5785983A (en) * 1991-05-23 1998-07-28 Euroresearch Srl Non-porous collagen sheet for therapeutic use, and the method and apparatus for preparing it
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
US5705178A (en) * 1991-05-31 1998-01-06 Gliatech, Inc. Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers
US5234914A (en) * 1991-06-11 1993-08-10 Patent Biopharmaceutics, Inc. Methods of treating hemorrhoids and anorecial disease
WO1992022304A1 (fr) * 1991-06-14 1992-12-23 Amgen Inc. Apport de medicament par film au collagene destine a des proteines
US5990095A (en) * 1991-07-03 1999-11-23 Hyal Pharmaceutical Corporation Use of hyaluronic acid and forms to prevent arterial restenosis
WO1994007505A1 (fr) * 1991-07-03 1994-04-14 Norpharmco Inc. Utilisation de l'acide hyaluronique sous differentes formes contre la recidive de la stenose arterielle
US6022866A (en) * 1991-07-03 2000-02-08 Hyal Pharmaceutical Corporation Use of hyaluronic acid and forms to prevent arterial restenosis
US6103704A (en) * 1991-07-03 2000-08-15 Hyal Pharmaceutical Corporation Therapeutic methods using hyaluronic acid
US5792753A (en) * 1991-07-03 1998-08-11 Hyal Pharmaceutical Corporation Compositions comprising hyaluronic acid and prostaglandin-synthesis-inhibiting drugs
US5817644A (en) * 1991-07-03 1998-10-06 Hyal Pharmaceutical Corporation Targeting of dosages of medicine and therapeutic agents
CA2071137A1 (fr) * 1991-07-10 1993-01-11 Clarence C. Lee Composition et methode pour la revitalisation du tissu cicatriciel
IT1251151B (it) * 1991-08-05 1995-05-04 Fidia Spa Materiale spugnoso essenzialmente costituito da acido ialuronico,o suoi derivati
WO1993003757A1 (fr) 1991-08-16 1993-03-04 Chiron Corporation Muteines du facteur de croissance epidermique (fce) presentant une meilleure liaison a un ph faible
CA2061567C (fr) * 1992-02-20 1998-02-03 Rudolf E. Falk Utilisation de l'acide hyaluronique pour reparer les dommages de reperfusion de l'ischemie
US6136793A (en) * 1992-02-20 2000-10-24 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
US20080233170A1 (en) * 1992-02-21 2008-09-25 Stryker Corporation Osteogenic Proteins
US6114314A (en) * 1992-02-21 2000-09-05 Hyal Pharmaceutical Corp. Formulations containing hyaluronic acid
GB9206509D0 (en) * 1992-03-25 1992-05-06 Jevco Ltd Heteromorphic sponges containing active agents
EP0567886A3 (fr) * 1992-04-21 1994-11-02 Kurashiki Boseki Kk Composition pour une couche pour la culture de cellules adhésives animales et procédé de culture des cellules dans un milieu sans sérum.
IL105529A0 (en) * 1992-05-01 1993-08-18 Amgen Inc Collagen-containing sponges as drug delivery for proteins
US5326350A (en) * 1992-05-11 1994-07-05 Li Shu Tung Soft tissue closure systems
US6350274B1 (en) 1992-05-11 2002-02-26 Regen Biologics, Inc. Soft tissue closure systems
US5928635A (en) * 1994-12-07 1999-07-27 Schmidt; Karlheinz Process for producing active agent complexes
US7214654B1 (en) 1994-12-07 2007-05-08 Karlheinz Schmidt Agent for the manufacture of biological parts including an active ingredient complex and carrying materials suitable for the active ingredient complex
US5916553A (en) * 1992-09-17 1999-06-29 Schmidt; Karlheinz Complex for inducing bone growth in the mastoid cavity
AU4926193A (en) * 1992-09-21 1994-04-12 Vitaphore Corporation Embolization plugs for blood vessels
US5331092A (en) * 1992-11-06 1994-07-19 Coletica Process of preparation of collagen containing in major proportion insoluble collagen and collagen having high mechanical resistance and thermal stability obtained thereby
WO1994017097A1 (fr) * 1993-01-19 1994-08-04 Regents Of The University Of Minnesota Fragments de fibronectine synthetique utilises comme inhibiteurs d'infections retrovirales
CA2119064A1 (fr) * 1993-03-17 1994-09-18 Richard A. Berg Systeme d'analyse dermo-epidermique in vitro
US5565210A (en) * 1993-03-22 1996-10-15 Johnson & Johnson Medical, Inc. Bioabsorbable wound implant materials
EP0702959B1 (fr) * 1993-05-31 2001-08-08 Kaken Pharmaceutical Co., Ltd. Preparation de gel a base de gelatine reticulee contenant un facteur de croissance de fibroblaste de base
US5700354A (en) * 1993-06-16 1997-12-23 Ranpak Corp. Paper strengthened with solubilized collagen and method
US5707491A (en) * 1993-06-16 1998-01-13 Ranpak Corporation Paper strengthened with solubilized collagen and method
US5711853A (en) * 1993-06-16 1998-01-27 Ranpak Corp. Paper strengthened with solubilized collagen and method
US5316942A (en) * 1993-06-16 1994-05-31 Battelle Memorial Institute Process for the production of low-cost soluble high-molecular weight collagen
AU693797B2 (en) 1993-07-19 1998-07-09 Angiotech Pharmaceuticals, Inc. Anti-angiogenic compositions and methods of use
US5487895A (en) * 1993-08-13 1996-01-30 Vitaphore Corporation Method for forming controlled release polymeric substrate
WO1995005161A1 (fr) * 1993-08-13 1995-02-23 Vitaphore Corporation Systemes de liberation de medicament contenant des microspheres a base d'hydrogel
GB2281861B (en) * 1993-09-21 1997-08-20 Johnson & Johnson Medical Bioabsorbable wound implant materials containing microspheres
US5616568A (en) * 1993-11-30 1997-04-01 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
SE9400036D0 (sv) * 1994-01-10 1994-01-10 Pharmacia Ab Low modecular weight hyaluronic acid
CA2140053C (fr) * 1994-02-09 2000-04-04 Joel S. Rosenblatt Systeme a base de collagene pour l'administration de drogue injectable, et utilisation
US5763416A (en) * 1994-02-18 1998-06-09 The Regent Of The University Of Michigan Gene transfer into bone cells and tissues
US6334872B1 (en) 1994-02-18 2002-01-01 Organogenesis Inc. Method for treating diseased or damaged organs
US5942496A (en) * 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US6074840A (en) 1994-02-18 2000-06-13 The Regents Of The University Of Michigan Recombinant production of latent TGF-beta binding protein-3 (LTBP-3)
US5962427A (en) * 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
DE4414755C2 (de) 1994-04-27 2000-11-16 Lohmann Therapie Syst Lts Kollagenzubereitung zur gesteuerten Abgabe von Wirkstoffen, Verfahren und Verwendung
US5558875A (en) * 1994-06-06 1996-09-24 Wang; Su Method of preparing collagenous tissue
DE69534233T2 (de) 1994-09-16 2005-10-27 Ethicon Endo-Surgery, Inc., Cincinnati Vorrichtungen zum bestimmen und markieren von gewebe
US5707962A (en) * 1994-09-28 1998-01-13 Gensci Regeneration Sciences Inc. Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof
US6180606B1 (en) 1994-09-28 2001-01-30 Gensci Orthobiologics, Inc. Compositions with enhanced osteogenic potential, methods for making the same and uses thereof
US6294202B1 (en) 1994-10-06 2001-09-25 Genzyme Corporation Compositions containing polyanionic polysaccharides and hydrophobic bioabsorbable polymers
US5891558A (en) * 1994-11-22 1999-04-06 Tissue Engineering, Inc. Biopolymer foams for use in tissue repair and reconstruction
US5709934A (en) * 1994-11-22 1998-01-20 Tissue Engineering, Inc. Bipolymer foams having extracellular matrix particulates
US5660854A (en) * 1994-11-28 1997-08-26 Haynes; Duncan H Drug releasing surgical implant or dressing material
US6485723B1 (en) 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US5695998A (en) * 1995-02-10 1997-12-09 Purdue Research Foundation Submucosa as a growth substrate for islet cells
US6962979B1 (en) * 1995-03-14 2005-11-08 Cohesion Technologies, Inc. Crosslinkable biomaterial compositions containing hydrophobic and hydrophilic crosslinking agents
US6337389B1 (en) * 1995-03-17 2002-01-08 Bioscience Consultants, L.L.C. Method and process for the production of collagen preparations from invertebrate marine animals and compositions thereof
US5714582A (en) * 1995-03-17 1998-02-03 Bioscience Consultants Invertebrate type V telopeptide collagen, methods of making, and use thereof
US5723010A (en) * 1995-03-31 1998-03-03 Toyo Boseki Kabushiki Kaisha Medical device and method for producing the same
US5733337A (en) 1995-04-07 1998-03-31 Organogenesis, Inc. Tissue repair fabric
US20020095218A1 (en) * 1996-03-12 2002-07-18 Carr Robert M. Tissue repair fabric
JP3799626B2 (ja) * 1995-04-25 2006-07-19 有限会社ナイセム 心臓血管修復材及びその製造方法
US20040002772A1 (en) * 1995-04-28 2004-01-01 Organogenesis, Inc. Tissue equivalents with perforations for improved integration to host tissues and methods for producing perforated tissue equivalents
PT831882E (pt) * 1995-06-07 2005-01-31 Organogenesis Inc Composicoes de segmentos de fibra de colagenio reconstituido e metodos de preparacao das mesmas
US6176240B1 (en) 1995-06-07 2001-01-23 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and their delivery
US6528483B2 (en) 1995-06-07 2003-03-04 André Beaulieu Method of producing concentrated non-buffered solutions of fibronectin
US7112320B1 (en) 1995-06-07 2006-09-26 Andre Beaulieu Solid wound healing formulations containing fibronectin
US5674292A (en) * 1995-06-07 1997-10-07 Stryker Corporation Terminally sterilized osteogenic devices and preparation thereof
US6705323B1 (en) 1995-06-07 2004-03-16 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and methods
US5792090A (en) * 1995-06-15 1998-08-11 Ladin; Daniel Oxygen generating wound dressing
JP2731833B2 (ja) * 1995-06-26 1998-03-25 大同ほくさん株式会社 海洋生物を原料とした代用皮膚
US6010694A (en) * 1995-07-27 2000-01-04 Thomas Jefferson University Fibrillin 1 gene comprising duplication mutation and compositions and kits using the same
US6106866A (en) * 1995-07-31 2000-08-22 Access Pharmaceuticals, Inc. In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles, including tumor sites
US5874500A (en) * 1995-12-18 1999-02-23 Cohesion Technologies, Inc. Crosslinked polymer compositions and methods for their use
US6423095B1 (en) * 1995-10-16 2002-07-23 Sdgi Holdings, Inc. Intervertebral spacers
US5733884A (en) * 1995-11-07 1998-03-31 Nestec Ltd. Enteral formulation designed for optimized wound healing
CA2164262A1 (fr) * 1995-12-01 1997-06-02 Charles J. Doillon Matiere poreuse biostable renfermant des biopolymeres mixtes
US6458889B1 (en) 1995-12-18 2002-10-01 Cohesion Technologies, Inc. Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
US7883693B2 (en) 1995-12-18 2011-02-08 Angiodevice International Gmbh Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
US6833408B2 (en) 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
US6231888B1 (en) 1996-01-18 2001-05-15 Perio Products Ltd. Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
GB2311027B (en) * 1996-03-15 1999-10-27 Johnson & Johnson Medical Coated bioabsorbable beads for wound treatment
US5788625A (en) 1996-04-05 1998-08-04 Depuy Orthopaedics, Inc. Method of making reconstructive SIS structure for cartilaginous elements in situ
US5834232A (en) * 1996-05-01 1998-11-10 Zymogenetics, Inc. Cross-linked gelatin gels and methods of making them
US5792478A (en) * 1996-07-08 1998-08-11 Advanced Uro Science Tissue injectable composition and method of use
US6666892B2 (en) 1996-08-23 2003-12-23 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
BR9711166A (pt) 1996-08-23 1999-08-17 Cook Biotech Inc PrÄtese de enxerto materiais para sua prepara-Æo e m-todos para seu uso
US8716227B2 (en) * 1996-08-23 2014-05-06 Cook Biotech Incorporated Graft prosthesis, materials and methods
US6165487A (en) * 1996-09-30 2000-12-26 Children's Medical Center Corporation Methods and compositions for programming an organic matrix for remodeling into a target tissue
FR2754268B1 (fr) * 1996-10-07 1998-12-24 Dev Des Utilisations Du Collag Composition adhesive a base de polyaldehyde macromoleculaire et procede de reticulation de collagene ou de gelatine
US5814328A (en) 1997-01-13 1998-09-29 Gunasekaran; Subramanian Preparation of collagen using papain and a reducing agent
US6221997B1 (en) 1997-04-28 2001-04-24 Kimberly Ann Woodhouse Biodegradable polyurethanes
US6123957A (en) * 1997-07-16 2000-09-26 Jernberg; Gary R. Delivery of agents and method for regeneration of periodontal tissues
US7923250B2 (en) 1997-07-30 2011-04-12 Warsaw Orthopedic, Inc. Methods of expressing LIM mineralization protein in non-osseous cells
WO1999006563A1 (fr) 1997-07-30 1999-02-11 Emory University Nouvelle proteine de mineralisation osseuse, adn, vecteurs et systemes d'expressions
DE19739031A1 (de) * 1997-09-05 1999-03-11 Suwelack Nachf Dr Otto Mittel zur peroralen Verabreichung, seine Herstellung und Verwendung
US7637948B2 (en) * 1997-10-10 2009-12-29 Senorx, Inc. Tissue marking implant
CA2346011C (fr) 1997-10-10 2009-01-20 Drexel University Matrices a nanofibres hybrides s'utilisant comme dispositifs de genie tissulaire
US8668737B2 (en) 1997-10-10 2014-03-11 Senorx, Inc. Tissue marking implant
US6270464B1 (en) 1998-06-22 2001-08-07 Artemis Medical, Inc. Biopsy localization method and device
US20040081704A1 (en) * 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
US5958874A (en) * 1998-02-18 1999-09-28 The Research Foundation Of State University Of New York Recombinant fibronectin-based extracellular matrix for wound healing
US6194378B1 (en) 1998-02-18 2001-02-27 The Research Foundation Of State University Of New York Fibronectin peptides-based extracellular matrix for wound healing
US6143293A (en) * 1998-03-26 2000-11-07 Carnegie Mellon Assembled scaffolds for three dimensional cell culturing and tissue generation
US6161034A (en) * 1999-02-02 2000-12-12 Senorx, Inc. Methods and chemical preparations for time-limited marking of biopsy sites
ATE424164T1 (de) * 1998-06-05 2009-03-15 Organogenesis Inc Verfahren zur herstellung einer gefässprothese
WO1999062425A2 (fr) * 1998-06-05 1999-12-09 Organogenesis Inc. Protheses de greffage vasculaire preparees a l'aide de techniques biologiques
WO1999062427A1 (fr) * 1998-06-05 1999-12-09 Organogenesis Inc. Protheses vasculaires greffees obtenues par genie biomedical
ES2323099T3 (es) * 1998-06-05 2009-07-06 Organogenesis Inc. Protesis de injerto tubulares producidas por bioingenieria.
US6630001B2 (en) 1998-06-24 2003-10-07 International Heart Institute Of Montana Foundation Compliant dehyrated tissue for implantation and process of making the same
US6458109B1 (en) 1998-08-07 2002-10-01 Hill-Rom Services, Inc. Wound treatment apparatus
US20020015724A1 (en) * 1998-08-10 2002-02-07 Chunlin Yang Collagen type i and type iii hemostatic compositions for use as a vascular sealant and wound dressing
US6630457B1 (en) * 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
US6531152B1 (en) 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
CA2346119C (fr) * 1998-10-14 2011-04-05 Orquest, Inc. Procede servant a declencher ou a renforcer la chondrogenese a l'aide d'une matrice extracellulaire contenant gdf-5
US8882850B2 (en) 1998-12-01 2014-11-11 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
DK1051116T3 (da) 1998-12-01 2009-02-02 Univ Washington Emboliseringsanordning
DE19856668A1 (de) * 1998-12-09 2000-06-15 Aesculap Ag & Co Kg Wirkstoffmatrix in Form eines biologisch resorbierbaren porösen Vlieses, Verfahren zu ihrer Herstellung und Verwendung
US6371904B1 (en) 1998-12-24 2002-04-16 Vivant Medical, Inc. Subcutaneous cavity marking device and method
US9669113B1 (en) 1998-12-24 2017-06-06 Devicor Medical Products, Inc. Device and method for safe location and marking of a biopsy cavity
US6356782B1 (en) 1998-12-24 2002-03-12 Vivant Medical, Inc. Subcutaneous cavity marking device and method
EP1022031B1 (fr) * 1999-01-21 2005-03-23 Nipro Corporation Membrane suturable pour la prévention d'adhérences
US6862470B2 (en) 1999-02-02 2005-03-01 Senorx, Inc. Cavity-filling biopsy site markers
US8361082B2 (en) 1999-02-02 2013-01-29 Senorx, Inc. Marker delivery device with releasable plug
US7651505B2 (en) * 2002-06-17 2010-01-26 Senorx, Inc. Plugged tip delivery for marker placement
US9820824B2 (en) 1999-02-02 2017-11-21 Senorx, Inc. Deployment of polysaccharide markers for treating a site within a patent
US8498693B2 (en) * 1999-02-02 2013-07-30 Senorx, Inc. Intracorporeal marker and marker delivery device
US20090216118A1 (en) 2007-07-26 2009-08-27 Senorx, Inc. Polysaccharide markers
US7983734B2 (en) 2003-05-23 2011-07-19 Senorx, Inc. Fibrous marker and intracorporeal delivery thereof
US6725083B1 (en) 1999-02-02 2004-04-20 Senorx, Inc. Tissue site markers for in VIVO imaging
US6375672B1 (en) * 1999-03-22 2002-04-23 Board Of Trustees Of Michigan State University Method for controlling the chemical and heat induced responses of collagenous materials
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
US6575991B1 (en) 1999-06-17 2003-06-10 Inrad, Inc. Apparatus for the percutaneous marking of a lesion
US6592794B1 (en) 1999-09-28 2003-07-15 Organogenesis Inc. Process of making bioengineered collagen fibrils
US6352708B1 (en) 1999-10-14 2002-03-05 The International Heart Institute Of Montana Foundation Solution and method for treating autologous tissue for implant operation
US6764462B2 (en) 2000-11-29 2004-07-20 Hill-Rom Services Inc. Wound treatment apparatus
US6824533B2 (en) 2000-11-29 2004-11-30 Hill-Rom Services, Inc. Wound treatment apparatus
US20090028953A1 (en) * 1999-12-10 2009-01-29 Yamamoto Ronald K Method of treatment using microparticulate biomaterial composition
US20030211166A1 (en) * 2001-07-31 2003-11-13 Yamamoto Ronald K Microparticulate biomaterial composition for medical use
US20030095993A1 (en) * 2000-01-28 2003-05-22 Hanne Bentz Gel-infused sponges for tissue repair and augmentation
WO2001054735A2 (fr) * 2000-01-28 2001-08-02 Orthogene, Inc. Eponges a base de collagene destinees a la reparation et a l'augmentation tissulaire
CN1411488A (zh) * 2000-02-03 2003-04-16 株式会社美你康 水溶性高分子材料构成的海绵状成型体及其空孔控制方法
US7039453B2 (en) * 2000-02-08 2006-05-02 Tarun Mullick Miniature ingestible capsule
CA2400401A1 (fr) * 2000-03-09 2001-09-13 Syntacoll Ag Nouveau materiau a base de polymere naturel, qui presente des proprietes ameliorees et est destine a un usage en medecine humaine et veterinaire, et son procede de production
JP2003525705A (ja) * 2000-03-09 2003-09-02 シンタコール アーゲー 組織再構築用の多層コラーゲンマトリックス
US20010046968A1 (en) * 2000-03-23 2001-11-29 Zagon Ian S. Opioid growth factor modulates angiogenesis
CA2409907A1 (fr) 2000-05-22 2001-11-29 Arthur C. Coffey Pansement combine sis et vide, et procede associe
US20050048614A1 (en) * 2000-06-13 2005-03-03 Children's Medical Center Corporation Biosynthetic oncolytic molecules and uses therefor
US6638312B2 (en) 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US8366787B2 (en) * 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US6599526B2 (en) * 2000-08-18 2003-07-29 The University Of North Texas Health Science Center At Fort Worth Pericardial anti-adhesion patch
EP1320390A2 (fr) * 2000-09-18 2003-06-25 Organogenesis Inc. Procedes de traitement de patients a l'aide de protheses greffees a feuilles planes cultivees par genie genetique
US20040028738A1 (en) * 2000-10-05 2004-02-12 Lynn L.H. Huang Process for the preparation of porous collagen matrix
WO2002039948A2 (fr) * 2000-11-14 2002-05-23 N.V.R. Labs Inc. Gels de laminine et d'acide hyaluronique reticule et leur utilisation dans la culture cellulaire et les implants medicaux
CA2775170C (fr) * 2000-11-20 2017-09-05 Senorx, Inc. Systeme d'apport de marqueur intracorporel pour marquer un site tissulaire
FR2816847B1 (fr) * 2000-11-22 2006-07-14 Assist Publ Hopitaux De Paris Biomateriaux polymeriques poreux, procede de preparation et utilisations
US6685681B2 (en) 2000-11-29 2004-02-03 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US6855135B2 (en) 2000-11-29 2005-02-15 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US7157614B1 (en) 2000-12-21 2007-01-02 Fountainhead, Llc Treatment devices providing targeted antimicrobial action
US20020114795A1 (en) * 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7041868B2 (en) 2000-12-29 2006-05-09 Kimberly-Clark Worldwide, Inc. Bioabsorbable wound dressing
US6620927B2 (en) * 2001-02-22 2003-09-16 Anika Therapeutics, Inc. Thiol-modified hyaluronan
US7119062B1 (en) 2001-02-23 2006-10-10 Neucoll, Inc. Methods and compositions for improved articular surgery using collagen
US6656488B2 (en) 2001-04-11 2003-12-02 Ethicon Endo-Surgery, Inc. Bioabsorbable bag containing bioabsorbable materials of different bioabsorption rates for tissue engineering
CA2388723C (fr) * 2001-06-06 2012-10-23 Becton, Dickinson & Company Methode de formation d'une matrice extracellulaire prete a l'emploi, a repartition uniforme, sur un support
WO2003002168A1 (fr) * 2001-06-29 2003-01-09 Cook Biotech Incorporated Dispositifs medicaux a matrice d'eponge poreuse et procedes
US7819918B2 (en) * 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
US7201917B2 (en) 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
JP4294474B2 (ja) 2001-07-16 2009-07-15 デピュイ・プロダクツ・インコーポレイテッド 半月板再生装置
US7163563B2 (en) 2001-07-16 2007-01-16 Depuy Products, Inc. Unitary surgical device and method
JP2004535245A (ja) * 2001-07-16 2004-11-25 デピュイ・プロダクツ・インコーポレイテッド 多孔質細胞外基質支持骨格材料および方法
EP1416866A4 (fr) 2001-07-16 2007-04-18 Depuy Products Inc Dispositifs a base de matieres biologiquement derivees d'origine naturelle
AU2002316696B2 (en) * 2001-07-16 2007-08-30 Depuy Products, Inc. Cartilage repair and regeneration scaffold and method
JP2005515802A (ja) 2001-07-16 2005-06-02 デピュイ・プロダクツ・インコーポレイテッド 混成生物／合成品型多孔質細胞外基質支持骨格
US8025896B2 (en) * 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
TW574302B (en) * 2001-08-10 2004-02-01 Ind Tech Res Inst A method for producing cross-linked hyaluronic acid-protein bio-composites
TWI284665B (en) * 2001-08-17 2007-08-01 Univ Nat Cheng Kung Fabrication method of the porous collagen matrix
US20030093041A1 (en) 2001-10-11 2003-05-15 Risk James R. Waste container for negative pressure therapy
US20030114061A1 (en) * 2001-12-13 2003-06-19 Kazuhisa Matsuda Adhesion preventive membrane, method of producing a collagen single strand, collagen nonwoven fabric and method and apparatus for producing the same
AU2002359829A1 (en) 2001-12-26 2003-07-24 Hill-Rom Services, Inc. Vacuum bandage packing
WO2003057070A2 (fr) 2001-12-26 2003-07-17 Hill-Rom Services Inc. Pansement sous vide ventile et procede
US7723560B2 (en) 2001-12-26 2010-05-25 Lockwood Jeffrey S Wound vacuum therapy dressing kit
US20030125683A1 (en) * 2001-12-31 2003-07-03 Reeves William G. Durably hydrophilic, non-leaching coating for hydrophobic substances
US20030155679A1 (en) * 2001-12-31 2003-08-21 Reeves William G. Method of making regenerated carbohydrate foam compositions
US20030143388A1 (en) * 2001-12-31 2003-07-31 Reeves William G. Regenerated carbohydrate foam composition
US20060189516A1 (en) * 2002-02-19 2006-08-24 Industrial Technology Research Institute Method for producing cross-linked hyaluronic acid-protein bio-composites
US8168848B2 (en) 2002-04-10 2012-05-01 KCI Medical Resources, Inc. Access openings in vacuum bandage
AUPS242702A0 (en) * 2002-05-21 2002-06-13 Colltech Australia Limited Improved method for the extraction and purification of collagen
US20060159731A1 (en) * 2002-06-03 2006-07-20 Yissum Research Development Company Of The Hebrew University Of Jerusalem Multi-layer collagenic article useful for wounds healing and a method for its production thereof
US7744913B2 (en) * 2002-06-24 2010-06-29 Incept, Llc Fillers and methods for displacing tissues to improve radiological outcomes
US7160326B2 (en) * 2002-06-27 2007-01-09 Depuy Products, Inc. Method and apparatus for implantation of soft tissue implant
CA2495385A1 (fr) 2002-08-21 2004-03-04 Hill-Rom Services, Inc. Pansement permettant d'empecher une blessure de se refermer
US7744651B2 (en) 2002-09-18 2010-06-29 Warsaw Orthopedic, Inc Compositions and methods for treating intervertebral discs with collagen-based materials
US20040054414A1 (en) * 2002-09-18 2004-03-18 Trieu Hai H. Collagen-based materials and methods for augmenting intervertebral discs
CN100394989C (zh) 2002-11-15 2008-06-18 华沙整形外科股份有限公司 包含微粒状基于胶原材料的组合物的制药应用和包含所述组合物的滑膜关节
US20060036158A1 (en) 2003-11-17 2006-02-16 Inrad, Inc. Self-contained, self-piercing, side-expelling marking apparatus
US20040122349A1 (en) * 2002-12-20 2004-06-24 Lafontaine Daniel M. Closure device with textured surface
US8709038B2 (en) * 2002-12-20 2014-04-29 Boston Scientific Scimed, Inc. Puncture hole sealing device
EP2181704B1 (fr) 2002-12-30 2015-05-06 Angiotech International Ag Liberation de médicaments a partir d'une composition polymère à gélification rapide
US7465766B2 (en) 2004-01-08 2008-12-16 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8137688B2 (en) 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US6982298B2 (en) 2003-01-10 2006-01-03 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8138265B2 (en) 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
WO2004078120A2 (fr) * 2003-02-28 2004-09-16 Fibrogen, Inc. Compositions et biomateriaux de collagene
US20040176855A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Decellularized liver for repair of tissue and treatment of organ deficiency
US20040175366A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Scaffold for cell growth and differentiation
WO2004082796A2 (fr) 2003-03-14 2004-09-30 The Trustees Of Columbia University In The City Ofnew York Systemes et procedes de traitements sanguins possedant un dispositif d'echange microfluidique sans membrane
US20060076295A1 (en) 2004-03-15 2006-04-13 The Trustees Of Columbia University In The City Of New York Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
US7877133B2 (en) 2003-05-23 2011-01-25 Senorx, Inc. Marker or filler forming fluid
CA2530490A1 (fr) 2003-06-25 2005-01-13 Stephen F. Badylak Compositions matricielles conditionnees pour la restauration d'un tissu
US7942897B2 (en) * 2003-07-10 2011-05-17 Boston Scientific Scimed, Inc. System for closing an opening in a body cavity
AU2004266154B2 (en) * 2003-08-22 2010-07-08 Synthes Gmbh Dura substitute and a process for producing the same
WO2005021580A2 (fr) * 2003-08-28 2005-03-10 Arizona Board Of Regents Hydrogels permettant la modulation de la migration cellulaire et depot matriciel
US7309232B2 (en) * 2003-10-10 2007-12-18 Dentigenix Inc. Methods for treating dental conditions using tissue scaffolds
CA2542946A1 (fr) 2003-10-28 2005-05-12 Medtronic, Inc. Procedes de preparation de materiaux reticules et de bioprotheses
US20050273002A1 (en) * 2004-06-04 2005-12-08 Goosen Ryan L Multi-mode imaging marker
WO2005061018A1 (fr) 2003-12-22 2005-07-07 Regentis Biomaterials Ltd. Matrice comprenant un squelette proteique reticule naturel
US7842667B2 (en) * 2003-12-22 2010-11-30 Regentis Biomaterials Ltd. Matrix composed of a naturally-occurring protein backbone cross linked by a synthetic polymer and methods of generating and using same
US20050148922A1 (en) * 2003-12-31 2005-07-07 Reeves William G. Thermoplastic composition and products made therefrom
US20050283256A1 (en) * 2004-02-09 2005-12-22 Codman & Shurtleff, Inc. Collagen device and method of preparing the same
US20050175659A1 (en) * 2004-02-09 2005-08-11 Macomber Laurel R. Collagen device and method of preparing the same
EP1731180B1 (fr) * 2004-03-31 2017-10-11 Nipro Corporation Kit antiadhésif, procédé pour produire celui-ci et procédé consistant à empêcher l'adhérence
KR100974733B1 (ko) 2004-04-28 2010-08-06 안지오디바이스 인터내셔널 게엠베하 가교된 생합성물질을 형성하기 위한 조성물 및 시스템, 및이와 관련된 제조 및 사용 방법
US7569233B2 (en) 2004-05-04 2009-08-04 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
FR2873927B1 (fr) * 2004-08-05 2007-05-11 Symatese Soc Par Actions Simpl Procede de preparation de collagene reticule et substitut osseux comprenant ledit collagene ainsi reticule
BRPI0514349A (pt) * 2004-08-13 2008-06-10 Ottawa Health Research Inst dispositivos oftálmicos para o reforço da visão e métodos e composições relacionadas
JP5459953B2 (ja) * 2004-09-09 2014-04-02 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 組織からのバイオマテリアルの単離方法およびそれから単離されたバイオマテリアル抽出物
EP1796602A4 (fr) 2004-09-17 2016-10-19 Angiotech Pharm Inc Composes multifonctionels pour la formation de biomateriaux reticules et leurs procedes de preparation et d'utilisation
EA012609B1 (ru) * 2004-09-30 2009-10-30 Ковалон Текнолоджиз Инк. Неадгезивные эластичные желатиновые матрицы
WO2006050213A2 (fr) * 2004-10-29 2006-05-11 Michalow Alexander E Methodes permettant de favoriser la cicatrisation de defauts cartilagineux et methode permettant d'induire la differentiation de cellules souches par la voie des chondrocytes articulaires
US7513866B2 (en) 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
US20060100138A1 (en) * 2004-11-10 2006-05-11 Olsen David R Implantable collagen compositions
US9044462B2 (en) 2004-12-08 2015-06-02 Avent, Inc. Method for oxygen treatment of intact skin
US20060121101A1 (en) * 2004-12-08 2006-06-08 Ladizinsky Daniel A Method for oxygen treatment of intact skin
US7354627B2 (en) 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
US8283312B2 (en) * 2005-02-04 2012-10-09 The Research Foundation Of State University Of New York Compositions and methods for modulating body weight and treating obesity-related disorders
US20060222596A1 (en) 2005-04-01 2006-10-05 Trivascular, Inc. Non-degradable, low swelling, water soluble radiopaque hydrogel polymer
JP5138580B2 (ja) 2005-04-06 2013-02-06 フジフィルム マニュファクチャリング ユーロプ ビー．ブイ． 細胞培養用非孔質フィルム
WO2006107188A1 (fr) 2005-04-06 2006-10-12 Fujifilm Manufacturing Europe B.V. Films non poreux pour cultiver des cellules
US10357328B2 (en) * 2005-04-20 2019-07-23 Bard Peripheral Vascular, Inc. and Bard Shannon Limited Marking device with retractable cannula
US8741832B2 (en) * 2005-06-10 2014-06-03 Albert Einstein College Of Medicine Of Yeshiva University Pegylated albumin and uses thereof
US20060293760A1 (en) * 2005-06-24 2006-12-28 Dedeyne Patrick G Soft tissue implants with improved interfaces
EP1741453A3 (fr) * 2005-07-07 2007-01-17 Nipro Corporation Support à base de collagène, méthode de préparation et utilisation
US7595062B2 (en) 2005-07-28 2009-09-29 Depuy Products, Inc. Joint resurfacing orthopaedic implant and associated method
CA2616865C (fr) * 2005-07-28 2014-07-08 Carnegie Mellon University Polymeres biocompatibles et procedes d'utilisation
CA2518298A1 (fr) * 2005-09-06 2007-03-06 Chaimed Technologies Inc. Polymeres biodegradables, leur preparation et leur usage pour la fabrication de pansements
US7429241B2 (en) * 2005-09-29 2008-09-30 Codman & Shurtleff, Inc. Dural graft and method of preparing the same
US8052658B2 (en) 2005-10-07 2011-11-08 Bard Peripheral Vascular, Inc. Drug-eluting tissue marker
US20070112360A1 (en) * 2005-11-15 2007-05-17 Patrick De Deyne Bioprosthetic device
JP2006181389A (ja) * 2006-03-10 2006-07-13 Angiotech Biomaterials Corp 架橋生体物質組成物を調製するための疎水性架橋剤の使用
ATE542583T1 (de) 2006-05-22 2012-02-15 Univ Columbia Verfahren für membranlosen mikrofluidaustausch in einem h-filter und filterung der extraktionsflüssigkeitsausgangsströme
US7872068B2 (en) * 2006-05-30 2011-01-18 Incept Llc Materials formable in situ within a medical device
CN105327393A (zh) 2006-06-22 2016-02-17 南佛罗里达大学 胶原支架、具有其的医用植入物以及使用方法
US20080003244A1 (en) * 2006-06-28 2008-01-03 Gary Viole Inflammation and Oxidative Stress Reducing Compostion for Topical or Oral Administration
US8118779B2 (en) 2006-06-30 2012-02-21 Warsaw Orthopedic, Inc. Collagen delivery device
US8399619B2 (en) 2006-06-30 2013-03-19 Warsaw Orthopedic, Inc. Injectable collagen material
US7945307B2 (en) * 2006-08-04 2011-05-17 Senorx, Inc. Marker delivery system with obturator
US20080294039A1 (en) * 2006-08-04 2008-11-27 Senorx, Inc. Assembly with hemostatic and radiographically detectable pellets
US20090171198A1 (en) * 2006-08-04 2009-07-02 Jones Michael L Powdered marker
KR100845515B1 (ko) * 2006-08-31 2008-07-10 포항공과대학교 산학협력단 골 충진 복합체 및 그 제조 방법
WO2008033505A1 (fr) 2006-09-13 2008-03-20 University Of South Florida Biocomposite pour tissu artificiel
EP2063859B1 (fr) * 2006-09-13 2017-01-18 Enhance Skin Products Inc. Composition cosmétique pour le traitement de la peau et procédés correspondants
ES2443526T3 (es) 2006-10-23 2014-02-19 C.R. Bard, Inc. Marcador mamario
US7871440B2 (en) 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
EP3542748B1 (fr) 2006-12-12 2023-08-16 C. R. Bard, Inc. Marqueur de tissu de mode d'imagerie multiples
US8401622B2 (en) * 2006-12-18 2013-03-19 C. R. Bard, Inc. Biopsy marker with in situ-generated imaging properties
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
BRPI0722363B8 (pt) * 2006-12-22 2021-06-22 Laboratoire Medidom S A patch de correção de cartilagem laminado implantável
JPWO2008081590A1 (ja) * 2006-12-27 2010-04-30 富士フイルム株式会社 医療用組成物
US8361503B2 (en) 2007-03-02 2013-01-29 University of Pittsburgh—of the Commonwealth System of Higher Education Extracellular matrix-derived gels and related methods
WO2008130068A1 (fr) * 2007-04-23 2008-10-30 Modern Cell & Tissue Technologies Inc. Procede de preparation d'un echafaudage polymere poreux a partir de glace seche
US8932619B2 (en) * 2007-06-27 2015-01-13 Sofradim Production Dural repair material
US8198087B2 (en) * 2007-07-30 2012-06-12 Sofradim Production Sas Tissue engineering support
US8834578B2 (en) * 2007-07-30 2014-09-16 Sofradim Production Bioresorbable implant
WO2009043052A1 (fr) * 2007-09-27 2009-04-02 Columbia University Procédés et systèmes de formation de matériaux biocompatibles
US9308068B2 (en) 2007-12-03 2016-04-12 Sofradim Production Implant for parastomal hernia
WO2009086535A2 (fr) * 2007-12-27 2009-07-09 The Trustees Of Columbia University In The City Of New York Systèmes et procédés de formation de matériaux de matrice extracellulaire comportant un motif
US8524494B2 (en) 2008-01-30 2013-09-03 Histogen, Inc. Low oxygen tension and BFGF generates a multipotent stem cell from a fibroblast in vitro
CN102066558B (zh) * 2008-01-30 2017-02-08 希斯托金公司 胞外基质组合物
US8530415B2 (en) * 2008-01-30 2013-09-10 Histogen, Inc. Repair and/or regeneration of cells with a composition produced by culturing fibroblast cells under hypoxic conditions
US8535913B2 (en) * 2008-01-30 2013-09-17 Histogen, Inc. Soluble composition for promoting hair growth produced by hypoxic culture of fibroblasts cells
US8311610B2 (en) * 2008-01-31 2012-11-13 C. R. Bard, Inc. Biopsy tissue marker
BRPI0907473A2 (pt) 2008-02-04 2019-09-24 Univ Columbia métodos, sistemas e dispositivos de separação de fluidos
EP2249891B1 (fr) 2008-02-13 2016-05-25 The Cleveland Clinic Foundation Augmentation moléculaire de la matrice extra-cellulaire et ses procédés d'utilisation
AU2009201541B2 (en) * 2008-04-23 2014-12-04 Integra Lifesciences Corporation Flowable collagen material for dural closure
US8410180B2 (en) 2008-04-30 2013-04-02 The Cleveland Clinic Foundation Methods to treat urinary incontinence
US9242026B2 (en) 2008-06-27 2016-01-26 Sofradim Production Biosynthetic implant for soft tissue repair
TWI432230B (zh) * 2008-08-14 2014-04-01 Kci Licensing Inc 組織支架
US9327061B2 (en) * 2008-09-23 2016-05-03 Senorx, Inc. Porous bioabsorbable implant
WO2010039823A2 (fr) 2008-09-30 2010-04-08 The Regents Of The University Of California Compositions et procédés de réparation tissulaire utilisant des matrices extracellulaires
AU2008365906B2 (en) 2008-12-30 2015-01-22 C.R. Bard Inc. Marker delivery device for tissue marker placement
US20100204570A1 (en) * 2009-02-06 2010-08-12 Paul Lubock Anchor markers
KR101834019B1 (ko) * 2009-07-10 2018-03-02 히스토젠, 인코포레이티드 저산소 조건 하에 배양된 세포로부터의 조정 배지 및 세포외 기질 조성물
US8652500B2 (en) 2009-07-22 2014-02-18 Acell, Inc. Particulate tissue graft with components of differing density and methods of making and using the same
US8298586B2 (en) 2009-07-22 2012-10-30 Acell Inc Variable density tissue graft composition
FR2949688B1 (fr) 2009-09-04 2012-08-24 Sofradim Production Tissu avec picots revetu d'une couche microporeuse bioresorbable
CA3042067C (fr) 2009-12-15 2022-10-18 Incept, Llc Implants et marqueurs de reference biodegradables
WO2012024390A2 (fr) 2010-08-17 2012-02-23 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Échafaudage composite biohybride
AU2011293386B2 (en) 2010-08-24 2014-08-21 The Regents Of The University Of California Compositions and methods for cardiac therapy
CA2817584C (fr) 2010-11-15 2018-01-02 Zimmer Orthobiologics, Inc. Substances de remplissage de vides osseux
US8551525B2 (en) 2010-12-23 2013-10-08 Biostructures, Llc Bone graft materials and methods
US8722854B2 (en) 2010-12-23 2014-05-13 Medskin Solutions Dr. Suwelack Ag Degradation-stabilised, biocompatible collagen matrices
FR2972626B1 (fr) 2011-03-16 2014-04-11 Sofradim Production Prothese comprenant un tricot tridimensionnel et ajoure
US20120310367A1 (en) 2011-05-31 2012-12-06 Lifecell Corporation Adipose tissue matrices
US9694106B2 (en) 2011-07-11 2017-07-04 Mimedx Group, Inc. Synthetic collagen threads for cosmetic uses including skin wrinkle treatments and associated methods
FR2977789B1 (fr) 2011-07-13 2013-07-19 Sofradim Production Prothese pour hernie ombilicale
FR2977790B1 (fr) 2011-07-13 2013-07-19 Sofradim Production Prothese pour hernie ombilicale
CA2849052C (fr) 2011-09-30 2019-11-05 Sofradim Production Raidissement reversible d'une maille de poids leger
JP5973873B2 (ja) * 2011-11-08 2016-08-23 Hoya株式会社 人工軟骨及びその製造方法
CA2858161C (fr) 2011-12-05 2020-03-10 Incept, Llc Procedes et compositions associes a un organogel medical
FR2985170B1 (fr) 2011-12-29 2014-01-24 Sofradim Production Prothese pour hernie inguinale
FR2985271B1 (fr) 2011-12-29 2014-01-24 Sofradim Production Tricot a picots
US9592278B2 (en) 2012-03-08 2017-03-14 Lifecell Corporation Enzyme-activated collagen and tissue matrices
CN102580139A (zh) * 2012-03-27 2012-07-18 黑龙江省华信药业有限公司 一种胶原透明质酸敷料
BR112015000547B1 (pt) 2012-07-13 2020-11-10 Lifecell Corporation método para tratar tecido
FR2994185B1 (fr) 2012-08-02 2015-07-31 Sofradim Production Procede de preparation d’une couche poreuse a base de chitosane
WO2014028657A1 (fr) 2012-08-15 2014-02-20 Mimedx Group, Inc Greffes de tissu placentaire renforcées et procédés de fabrication et d'utilisation de celles-ci
FR2995778B1 (fr) 2012-09-25 2015-06-26 Sofradim Production Prothese de renfort de la paroi abdominale et procede de fabrication
FR2995779B1 (fr) 2012-09-25 2015-09-25 Sofradim Production Prothese comprenant un treillis et un moyen de consolidation
FR2995788B1 (fr) 2012-09-25 2014-09-26 Sofradim Production Patch hemostatique et procede de preparation
CA2885327A1 (fr) 2012-09-26 2014-04-03 Lifecell Corporation Tissu adipeux traite
FR2995904B1 (fr) 2012-09-27 2015-09-18 Sofradim Production Procede de preparation d'une couche poreuse
US10159555B2 (en) 2012-09-28 2018-12-25 Sofradim Production Packaging for a hernia repair device
US9180145B2 (en) 2012-10-12 2015-11-10 Mimedx Group, Inc. Compositions and methods for recruiting and localizing stem cells
US8940684B2 (en) * 2012-11-19 2015-01-27 Mimedx Group, Inc. Cross-linked collagen comprising an antifungal agent
US9155799B2 (en) 2012-11-19 2015-10-13 Mimedx Group, Inc. Cross-linked collagen with at least one bound antimicrobial agent for in vivo release of the agent
US8946163B2 (en) 2012-11-19 2015-02-03 Mimedx Group, Inc. Cross-linked collagen comprising metallic anticancer agents
US10111910B2 (en) 2013-01-18 2018-10-30 Mimedx Group, Inc. Methods for treating cardiac conditions
US10206977B1 (en) 2013-01-18 2019-02-19 Mimedx Group, Inc. Isolated placental stem cell recruiting factors
JP5909610B2 (ja) * 2013-02-15 2016-04-27 国立大学法人大阪大学 コラーゲンスポンジ
US10029030B2 (en) 2013-03-15 2018-07-24 Mimedx Group, Inc. Molded placental tissue compositions and methods of making and using the same
US10335433B2 (en) 2013-04-10 2019-07-02 Mimedx Group, Inc. NDGA polymers and metal complexes thereof
US9446142B2 (en) 2013-05-28 2016-09-20 Mimedx Group, Inc. Polymer chelator conjugates
FR3006578B1 (fr) 2013-06-07 2015-05-29 Sofradim Production Prothese a base d’un textile pour voie laparoscopique
FR3006581B1 (fr) 2013-06-07 2016-07-22 Sofradim Production Prothese a base d’un textile pour voie laparoscopique
WO2015031681A1 (fr) 2013-08-30 2015-03-05 Mimedx Group, Inc. Compositions placentaires micronisées comprenant un chélateur
USD716450S1 (en) 2013-09-24 2014-10-28 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD716451S1 (en) 2013-09-24 2014-10-28 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD715942S1 (en) 2013-09-24 2014-10-21 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD715442S1 (en) 2013-09-24 2014-10-14 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
US10052351B2 (en) 2014-01-17 2018-08-21 Mimedx Group, Inc. Method for inducing angiogenesis
CN111265719B (zh) 2014-03-21 2023-01-10 匹兹堡大学-联邦高等教育体系 最终消毒的来自细胞外基质的水凝胶的制备方法
WO2015181395A1 (fr) 2014-05-30 2015-12-03 Sofradim Production Procédé de préparation de matrice neutralisée de matière de collagène non-antigénique
AU2015308795B2 (en) 2014-08-28 2019-05-23 Mimedx Group, Inc. Collagen reinforced tissue grafts
US11028140B2 (en) * 2014-09-22 2021-06-08 Northeast Ohio Medical University Osteogenic biomaterial
EP3000488A1 (fr) 2014-09-26 2016-03-30 Sofradim Production Méthode pour préparer des matrices de chitosane ayant des propriétés mécaniques améliorées
EP3000432B1 (fr) 2014-09-29 2022-05-04 Sofradim Production Prothèse à base textile pour le traitement d'une hernie inguinale
EP3000433B1 (fr) 2014-09-29 2022-09-21 Sofradim Production Dispositif pour introduire une prothèse pour le traitement de la hernie dans une incision et prothèse textile flexible
WO2016084413A1 (fr) * 2014-11-27 2016-06-02 東洋紡株式会社 Corps composite poreux, matériau de régénération osseuse et procédé de production de corps composite poreux
EP3029189B1 (fr) 2014-12-05 2021-08-11 Sofradim Production Tricot poreux prothétique, procédé pour son obtention et prothèse à hernie
EP3059255B1 (fr) 2015-02-17 2020-05-13 Sofradim Production Méthode pour préparer une matrice de chitosane comprenant un élément de renfort fibreux
US11919941B2 (en) 2015-04-21 2024-03-05 Purdue Research Foundation Cell-collagen-silica composites and methods of making and using the same
EP3085337B1 (fr) 2015-04-24 2022-09-14 Sofradim Production Prothèse pour supporter une structure mammaire
EP3088010B1 (fr) 2015-04-28 2022-12-21 DiCosmo, Frank Biomatériaux à base de collagène bioactif et leurs procédés de fabrication
ES2676072T3 (es) 2015-06-19 2018-07-16 Sofradim Production Prótesis sintética que comprende un tejido de punto y una película no porosa y método para formarla
EP3195830B1 (fr) 2016-01-25 2020-11-18 Sofradim Production Prothèse de réparation de hernie
EP3777907A1 (fr) 2016-07-05 2021-02-17 LifeCell Corporation Matrices tissulaires incorporant de plusieurs types de tissus
EP3312325B1 (fr) 2016-10-21 2021-09-22 Sofradim Production Méthode pour la fabrication un treillis avec suture crantée attachée et treillis ainsi obtenu
AU2018226871B2 (en) 2017-03-02 2023-08-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix (ECM) hydrogel and soluble fraction thereof for the treatment of cancer
EP3615568A4 (fr) 2017-04-25 2021-01-20 Purdue Research Foundation Muscle artificiel tridimensionnel (3d) de restauration tissulaire
EP3398554A1 (fr) 2017-05-02 2018-11-07 Sofradim Production Prothèse pour réparation de hernie inguinale
EP3621663A4 (fr) * 2017-05-10 2021-01-27 Marquette University Biomatériaux médicaux et dentaires multiphases intégrés pour la reconstruction/régénération d'un seul tissu ou de plusieurs tissus
CN107320786B (zh) * 2017-06-16 2020-06-23 卓阮医疗科技（苏州）有限公司 一种缓释抗感染的复合软组织修复材料及其制备方法
AU2018351051A1 (en) 2017-10-18 2020-03-19 Lifecell Corporation Adipose tissue products and methods of production
US11123375B2 (en) 2017-10-18 2021-09-21 Lifecell Corporation Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
US11246994B2 (en) 2017-10-19 2022-02-15 Lifecell Corporation Methods for introduction of flowable acellular tissue matrix products into a hand
AU2018351314A1 (en) 2017-10-19 2020-03-19 Lifecell Corporation Flowable acellular tissue matrix products and methods of production
CN112513173A (zh) 2018-04-02 2021-03-16 聚合物绿色有限责任公司 基于苯乙烯马来酸共聚物和生物聚合物的具有高负载下吸收率的可生物降解高吸水性聚合物的制备方法
CN108478869A (zh) * 2018-04-17 2018-09-04 上海市第六人民医院 一种再生修复用脱细胞青鱼皮仿生基质及其制备方法和应用
US11517644B2 (en) * 2018-11-02 2022-12-06 Covalon Technologies Inc. Foam compositions, foam matrices and methods
EP3880770B1 (fr) 2018-11-13 2023-08-09 Polygreen Ltd. Composition polymère destinée à être utilisée en tant qu'amendement de sol présentant une capacité d'absorption d'eau améliorée pendant l'arrosage des cultures agricoles
EP3653171B1 (fr) 2018-11-16 2024-08-21 Sofradim Production Implants conçus pour la réparation de tissus mous
RU2704623C1 (ru) * 2018-12-07 2019-10-30 Общество с ограниченной ответственностью "Научно-производственное объединение "Ликом" Перевязочное средство на биополимерной основе
BR112021024043A2 (pt) 2019-05-30 2022-02-08 Lifecell Corp Implante mamário biológico
US12064330B2 (en) 2020-04-28 2024-08-20 Covidien Lp Implantable prothesis for minimally invasive hernia repair
CN115029402A (zh) * 2021-03-05 2022-09-09 湖州蔻婷生物科技有限公司 一种寡聚透明质酸及其水解胶原蛋白和纤连蛋白复配化妆品组合物
CN114010839B (zh) * 2021-11-09 2022-11-29 深圳齐康医疗器械有限公司 一种梯度降解人工真皮及其制备方法和应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3098693A (en) * 1960-05-27 1963-07-23 Little Inc A Treatment of protein and peptide materials to form amide linkages
US3300470A (en) * 1963-10-04 1967-01-24 Swift & Co Reaction products of protein with cyanamide under acidic conditions
US3955012A (en) * 1970-08-06 1976-05-04 Zaidan Hojin, Seisan Kaihatsu Kagaku Kenkyusho Method for manufacturing medical articles composed of silicone rubber coated with collagen
US3800792A (en) * 1972-04-17 1974-04-02 Johnson & Johnson Laminated collagen film dressing
US3903882A (en) * 1974-04-19 1975-09-09 American Cyanamid Co Composite dressing
US4280954A (en) * 1975-07-15 1981-07-28 Massachusetts Institute Of Technology Crosslinked collagen-mucopolysaccharide composite materials
US4060081A (en) * 1975-07-15 1977-11-29 Massachusetts Institute Of Technology Multilayer membrane useful as synthetic skin
US4193813A (en) * 1976-09-07 1980-03-18 Medi-Coll, Inc. Method for making collagen sponge
DE2734503C2 (de) * 1977-07-30 1984-04-05 Fa. Carl Freudenberg, 6940 Weinheim Verfahren zur Herstellung von Kollagenschwamm
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4412947A (en) * 1979-09-12 1983-11-01 Seton Company Collagen sponge
US4374121A (en) * 1979-09-12 1983-02-15 Seton Company Macromolecular biologically active collagen articles
US4399123A (en) * 1980-04-01 1983-08-16 Oliver Roy F Fibrous tissue dressing or implant
US4522753A (en) * 1980-07-17 1985-06-11 Massachusetts Institute Of Technology Method for preserving porosity in porous materials
US4440680A (en) * 1980-09-24 1984-04-03 Seton Company Macromolecular biologically active collagen articles
JPS57106625A (en) * 1980-12-22 1982-07-02 Teijin Ltd Cytotoxic protein complex and its preparation
US4350629A (en) * 1981-07-29 1982-09-21 Massachusetts Institute Of Technology Procedures for preparing composite materials from collagen and glycosaminoglycan
US4458678A (en) * 1981-10-26 1984-07-10 Massachusetts Institute Of Technology Cell-seeding procedures involving fibrous lattices
US4418691A (en) * 1981-10-26 1983-12-06 Massachusetts Institute Of Technology Method of promoting the regeneration of tissue at a wound
US4409332A (en) * 1982-01-12 1983-10-11 Jefferies Steven R Collagen-enzyme conjugates that exhibit no inflammatory response and method for making the same

Also Published As

Publication number Publication date
CN85101396A (zh) 1987-01-31
AR240608A1 (es) 1990-06-30
US4970298A (en) 1990-11-13
FI854692A (fi) 1985-11-27
US4703108A (en) 1987-10-27
MX163953B (es) 1992-07-03
FI854692A0 (fi) 1985-11-27
ES8605988A1 (es) 1986-04-01
DK547485D0 (da) 1985-11-27
BR8506206A (pt) 1986-04-15
EP0177573B1 (fr) 1992-01-02
WO1985004413A1 (fr) 1985-10-10
DK547485A (da) 1986-01-24
IT8547869A1 (it) 1986-09-26
IL74715A0 (en) 1985-06-30
DE3585069D1 (de) 1992-02-13
IT8547869A0 (it) 1985-03-26
CA1295796C (fr) 1992-02-18
JPH0811121B2 (ja) 1996-02-07
ES541629A0 (es) 1986-04-01
IT1182725B (it) 1987-10-05
AU4210585A (en) 1985-11-01
JPS61502129A (ja) 1986-09-25
EP0177573A1 (fr) 1986-04-16

Similar Documents

Publication Publication Date Title
NO854723L (no) Bionedbrytbar matriks og fremgangsmaate for fremstilling av denne.
US5350583A (en) Cell-penetrable medical material and artificial skin
US4060081A (en) Multilayer membrane useful as synthetic skin
US4572906A (en) Chitosan based wound dressing materials
Meena et al. Biomedical and industrial applications of collagen
US6706684B1 (en) Method for preparing a collagen material with controlled in vivo degradation
EP0296078B1 (fr) Nouveaux biomatériaux à base de mélanges de collagène, de chitosan et de glycosaminoglycanes, leur procédé de préparation ainsi que leurs applications en médecine humaine
US5263983A (en) Medical material and prosthetic skin in which cells can invade
US4409332A (en) Collagen-enzyme conjugates that exhibit no inflammatory response and method for making the same
CA2270599C (fr) Modification chimique de materiaux biomedicaux par la genipine
US20090035356A1 (en) Modified biodegradable polymers, preparation and use thereof for making biomaterials and dressings
JPH08500334A (ja) タンパク質用薬剤デリバリーとして有用なコラーゲン含有スポンジ
JP2002524209A (ja) 膠原組織組成物
US20030095997A1 (en) Natural polymer-based material for use in human and veterinary medicine and method of manufacturing
Omura et al. A newly developed collagen/silicone bilayer membrane as a mucosal substitute: a preliminary report
CA1213520A (fr) Copolyelectrolytes biopolymeres hydrophiles, et pansements biodegradables qui les renferment
Liu et al. Sutureless transplantation using a semi-interpenetrating polymer network bioadhesive for ocular surface reconstruction
CA2142209A1 (fr) Implants de collagene dont l'elasticite est accrue
EP0411124B1 (fr) Substance medicale dans laquelle les cellules peuvent penetrer et peau artificielle
JP5946774B2 (ja) 複合母材
JPS60224631A (ja) 裂傷癒着用組成物
CN115671365A (zh) 交联重组胶原蛋白海绵及其制备方法和应用
WO2003094985A1 (fr) Matrice extracellulaire artificielle et procede de fabrication associe
JP3105308B2 (ja) 人工皮膚およびその製造法
CN112386740A (zh) 一种成纤维细胞生长因子自粘性人工硬膜修补片及其制备方法