BRPI0514349A - dispositivos oftálmicos para o reforço da visão e métodos e composições relacionadas - Google Patents

dispositivos oftálmicos para o reforço da visão e métodos e composições relacionadas

Info

Publication number
BRPI0514349A
BRPI0514349A BRPI0514349-7A BRPI0514349A BRPI0514349A BR PI0514349 A BRPI0514349 A BR PI0514349A BR PI0514349 A BRPI0514349 A BR PI0514349A BR PI0514349 A BRPI0514349 A BR PI0514349A
Authority
BR
Brazil
Prior art keywords
compositions
devices
related methods
vision
corneal
Prior art date
Application number
BRPI0514349-7A
Other languages
English (en)
Inventor
May Griffith
David J Carlsson
Fengfu Li
Yuwen Liu
Christopher J Marmo
Mehrdad Asmanrafat
Original Assignee
Ottawa Health Research Inst
Ca Nat Research Council
Coopervision Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ottawa Health Research Inst, Ca Nat Research Council, Coopervision Inc filed Critical Ottawa Health Research Inst
Publication of BRPI0514349A publication Critical patent/BRPI0514349A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Abstract

DISPOSITIVOS OFTáLMICOS PARA O REFORçO DA VISãO E MéTODOS E COMPOSIçõES RELACIONADAS São descritos dispositivos, métodos, e composições para o aperfeiçoamento da visão ou para o tratamento de doenças, distúrbios ou traumas do olho. Dispositivos oftálmicos, tais como sobrepostos de córnea, embutidos de córnea, e implantes de córnea de espessura plena, são feitos de um material que é eficaz na facilitação do crescimento de nervos através ou sobre o dispositivo. O material pode incluir uma quantidade de colágeno maior que 1% (p/p), tal como entre cerca de 10% (p/p) e cerca de 30% (p/p) O material pode incluir polímeros de colágeno e/ou um segundo biopolímero ou polímero sintético solúvel em água reticulado usando química de EDC/NHS. O material pode adicionalmente compreender um polímero sintético. Os dispositivos são colocados em um olho para corrigir ou aperfeiçoar visão de um indivíduo ou para tratar uma doença, distúrbio ou trauma de um olho de um indivíduo.
BRPI0514349-7A 2004-08-13 2005-08-12 dispositivos oftálmicos para o reforço da visão e métodos e composições relacionadas BRPI0514349A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60127004P 2004-08-13 2004-08-13
PCT/US2005/028723 WO2006020859A2 (en) 2004-08-13 2005-08-12 Vision enhancing ophthalmic devices and related methods and compositions

Publications (1)

Publication Number Publication Date
BRPI0514349A true BRPI0514349A (pt) 2008-06-10

Family

ID=35839107

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0514349-7A BRPI0514349A (pt) 2004-08-13 2005-08-12 dispositivos oftálmicos para o reforço da visão e métodos e composições relacionadas

Country Status (9)

Country Link
US (2) US20060134170A1 (pt)
EP (2) EP1776148B1 (pt)
JP (3) JP2008508959A (pt)
KR (2) KR20070053217A (pt)
CN (2) CN101132818A (pt)
BR (1) BRPI0514349A (pt)
CA (2) CA2576308C (pt)
TW (2) TWI388349B (pt)
WO (2) WO2006020859A2 (pt)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8668735B2 (en) 2000-09-12 2014-03-11 Revision Optics, Inc. Corneal implant storage and delivery devices
BR0314266A (pt) 2002-09-13 2005-07-26 Ocular Sciences Inc Dispositivos e métodos para a melhora de visão
US8185209B2 (en) * 2003-01-03 2012-05-22 Board Of Trustees Operating Michigan State University Methods to extend vision to infrared wavelengths
US10835371B2 (en) 2004-04-30 2020-11-17 Rvo 2.0, Inc. Small diameter corneal inlay methods
JP2008508959A (ja) * 2004-08-13 2008-03-27 オタワ ヘルス リサーチ インスティテュート 眼用器具及び関連した方法及び組成物
US8029515B2 (en) * 2005-01-31 2011-10-04 Yichieh Shiuey Corneal implants and methods and systems for placement
US7261412B2 (en) * 2005-06-30 2007-08-28 Visx, Incorporated Presbyopia correction through negative high-order spherical aberration
EP2535041A1 (en) * 2005-09-09 2012-12-19 Ottawa Health Research Institute Interpenetrating networks, and related methods and composition
US10555805B2 (en) 2006-02-24 2020-02-11 Rvo 2.0, Inc. Anterior corneal shapes and methods of providing the shapes
US7883520B2 (en) 2006-04-10 2011-02-08 Forsight Labs, Llc Corneal epithelial pocket formation systems, components and methods
EP2019646A4 (en) * 2006-05-04 2013-12-04 Herbert Kaufman METHOD, DEVICE AND SYSTEM FOR THE RELEASE OF A THERAPEUTIC ACTIVE IN THE EYE
KR101335884B1 (ko) * 2006-07-24 2013-12-12 인터내셔날 스템 셀 코포레이션 망막 줄기 세포로부터 유래한 합성 각막
WO2008014330A2 (en) 2006-07-25 2008-01-31 Lai Shui T Method of making high precision optics having a wavefront profile
ES2668641T3 (es) * 2006-07-26 2018-05-21 Shui T. Lai Cirugía intraestromal para corregir aberraciones de bajo orden y de alto orden del ojo
WO2008014419A2 (en) 2006-07-26 2008-01-31 Lai Shui T Intrastromal surgery correcting low order and high order aberrations of the eye
US20110212524A1 (en) * 2006-12-04 2011-09-01 Body Organ Biomedical Corporation Biomaterial and preparation method thereof
US7746649B2 (en) * 2007-01-08 2010-06-29 Rockwell Automation Technologies, Inc. Modular soft starter
US9271828B2 (en) 2007-03-28 2016-03-01 Revision Optics, Inc. Corneal implant retaining devices and methods of use
US9549848B2 (en) 2007-03-28 2017-01-24 Revision Optics, Inc. Corneal implant inserters and methods of use
US20080293637A1 (en) * 2007-05-23 2008-11-27 Allergan, Inc. Cross-linked collagen and uses thereof
US20080300679A1 (en) * 2007-06-01 2008-12-04 Altmann Griffith E Diffractive Intraocular Lens
US8507659B2 (en) * 2007-11-28 2013-08-13 Fujifilm Corporation Method for chemically modifying biopolymer and polypeptide
JP5525823B2 (ja) * 2007-12-28 2014-06-18 満 明石 積層コラーゲンゲルの作製方法及び積層コラーゲンゲル
KR101572634B1 (ko) 2008-04-04 2015-12-01 포사이트 비젼4, 인크. 통증 관리 및 시력을 위한 치료 장치
US9539143B2 (en) 2008-04-04 2017-01-10 Revision Optics, Inc. Methods of correcting vision
JP2011516180A (ja) 2008-04-04 2011-05-26 レヴィジオン・オプティックス・インコーポレーテッド 視力を矯正する角膜インレー設計および方法
US9095404B2 (en) 2008-05-12 2015-08-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US10064819B2 (en) 2008-05-12 2018-09-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
WO2009140246A2 (en) 2008-05-12 2009-11-19 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US9877973B2 (en) 2008-05-12 2018-01-30 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
JP5388090B2 (ja) * 2008-05-29 2014-01-15 国立大学法人東北大学 強膜透明化による角膜移植材料調製方法
US8283322B2 (en) * 2008-08-15 2012-10-09 Orthopeutics, Lp Formulations for nonsurgical exogenous crosslink therapy
US20100040593A1 (en) * 2008-08-15 2010-02-18 Orthopeutics, Lp Formulations for nonsurgical exogenous crosslink therapy
US8198248B2 (en) * 2008-08-15 2012-06-12 Orthopeutics, Lp Formulations for nonsurgical exogenous crosslink therapy
ES2658609T3 (es) 2008-09-02 2018-03-12 Tautona Group Lp Hilos de ácido hialurónico y/o derivados de los mismos, métodos para fabricar los mismos, y usos de los mismos
US20100198348A1 (en) * 2009-01-30 2010-08-05 Hiles Michael C Biomaterials with modified optical character and methods for preparing and using same
JP5988588B2 (ja) * 2009-03-10 2016-09-07 ザ ジョーンズ ホプキンズ ユニバーシティＴｈｅ Ｊｏｈｎｓ Ｈｏｐｋｉｎｓ Ｕｎｉｖｅｒｓｉｔｙ 生物学的組織結合及び修復装置及びその使用方法
EP2483332B1 (en) * 2009-09-30 2018-06-20 Ottawa Hospital Research Institute Crosslinked hydrogels and related method of preparation
NO2490635T3 (pt) 2009-10-23 2018-02-03
WO2011050365A1 (en) 2009-10-23 2011-04-28 Forsight Labs, Llc Conformable therapeutic shield for vision and pain
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
WO2011119468A1 (en) 2010-03-22 2011-09-29 Allergan, Inc. Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation
CN201689229U (zh) * 2010-06-04 2010-12-29 柏登生医股份有限公司 具有角膜修补功能的隐形眼镜
US9622911B2 (en) 2010-09-30 2017-04-18 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use
WO2012070680A1 (ja) * 2010-11-26 2012-05-31 国立大学法人東京工業大学 コラーゲン非線維化成形体及びその製造方法
US9211256B2 (en) 2011-03-08 2015-12-15 The Johns Hopkins University Wound healing compositions comprising biocompatible cellulose hydrogel membranes and methods of use thereof
US8871016B2 (en) 2011-08-03 2014-10-28 The Johns Hopkins University Cellulose-based hydrogels and methods of making thereof
US9175153B2 (en) 2011-03-08 2015-11-03 The Johns Hopkins University Cellulose hydrogel compositions and contact lenses for corneal applications
US9186243B2 (en) * 2011-05-31 2015-11-17 Novartis Ag Accommodative intraocular lens and method of implantation
WO2012167079A2 (en) 2011-06-03 2012-12-06 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
WO2014039607A1 (en) * 2012-09-06 2014-03-13 Allergan, Inc. Hyaluronic acid/collagen- based dermal filler compositions and methods for making same
AU2012325705B2 (en) 2011-10-21 2017-07-20 Revision Optics, Inc. Corneal implant storage and delivery devices
CN102552975B (zh) * 2012-02-28 2013-09-11 青岛中皓生物工程有限公司 一种组织工程人角膜基质载体支架及其制备方法
RU2475248C1 (ru) * 2012-03-12 2013-02-20 Государственное бюджетное учреждение "Уфимский научно-исследовательский институт глазных болезней Академии наук Республики Башкортостан" Офтальмологическое средство-2 для кросслинкинга
US9566301B2 (en) 2012-03-29 2017-02-14 Cxl Ophthalmics, Llc Compositions and methods for treating or preventing diseases associated with oxidative stress
WO2013148895A1 (en) 2012-03-29 2013-10-03 Cxl Ophthalmics, Llc Ocular cross-linking system and method for sealing corneal wounds
WO2013148896A1 (en) 2012-03-29 2013-10-03 Cxl Ophthalmics, Llc Ocular treatment solutions, delivery devices and delivery augmentation methods
US10092393B2 (en) 2013-03-14 2018-10-09 Allotex, Inc. Corneal implant systems and methods
JP6310072B2 (ja) 2013-06-26 2018-04-11 ネクシスビジョン， インコーポレイテッド 屈折矯正のためのコンタクトレンズ
CN103333270B (zh) * 2013-07-02 2016-05-11 武汉理工大学 胶原蛋白肽接枝海藻酸钠硫酸酯、制备方法及其用途
ES2761558T3 (es) 2014-09-30 2020-05-20 Allergan Ind Sas Composiciones de hidrogel estables que incluyen aditivos
KR101531479B1 (ko) * 2014-11-21 2015-06-26 세원셀론텍(주) 의료용 재료로 사용하기 위한 고농도 콜라겐 제조방법
WO2016144404A1 (en) 2015-03-12 2016-09-15 Revision Optics, Inc. Methods of correcting vision
KR101690539B1 (ko) 2015-07-30 2016-12-29 주식회사 아이바이오코리아 건성안 예방 또는 치료용 약학조성물
US10449090B2 (en) 2015-07-31 2019-10-22 Allotex, Inc. Corneal implant systems and methods
TWI635877B (zh) 2015-12-18 2018-09-21 財團法人工業技術研究院 用於保護眼內組織的薄膜及其保護方法
SE539167C2 (en) * 2015-12-22 2017-05-02 Rafat Mehrdad A composite collagen hydrogel material, an implantable ophthalmic device comprising such material and methods of producing the composite collagen hydrogel material and the implantable ophthalmic device
WO2017107638A1 (zh) * 2015-12-25 2017-06-29 深圳艾尼尔角膜工程有限公司 一种角膜包装体的自动化分类收集系统及方法
CN113456889B (zh) * 2016-07-27 2022-06-28 珐博进(中国)医药技术开发有限公司 生物合成角膜
CA3067212A1 (en) 2017-06-16 2018-12-20 AesculaTech, Inc. Thermoresponsive polymers and uses thereof
KR102015624B1 (ko) 2017-11-15 2019-08-28 고려대학교산학협력단 데스메막 이동 부착막
CN108277204A (zh) * 2018-01-10 2018-07-13 山东麦德克斯生物科技有限公司 一种生物工程培育眼全层角膜的方法
WO2019167040A1 (en) * 2018-03-01 2019-09-06 Bar Ilan University System, method and material composition for use in correction of eye conditions
KR101979286B1 (ko) * 2018-05-17 2019-05-15 경북대학교병원 부분 경화된 콘택트렌즈형 양막 드레싱 및 이의 제조방법
CN108498862A (zh) * 2018-06-21 2018-09-07 常州大学 一种氧化石墨烯改性角膜修复材料及其制备方法
DE202020005758U1 (de) * 2019-10-06 2022-05-20 Precise Bio 3D Ltd. Biotechnologische Hornhauttransplantate
WO2022272107A1 (en) * 2021-06-24 2022-12-29 Rvo 2.0, Inc, D/B/A Optics Medical Corneal inlay implant
WO2022272082A1 (en) * 2021-06-24 2022-12-29 Rvo 2.0, Inc, D/B/A Optics Medical Corneal onlay medical device
CN113713086A (zh) * 2021-08-20 2021-11-30 山西锦波生物医药股份有限公司 一种含有重组iii型人源化胶原蛋白的组合物及其制备方法和用途
CN113773380A (zh) * 2021-09-28 2021-12-10 山东汉肽医美生物科技有限公司 一种重组人胶原蛋白、编码基因及其在制备可生物降解的胶原基角膜替代物上的应用
CN115518206B (zh) * 2022-10-18 2024-01-23 华中科技大学同济医学院附属协和医院 一种自矿化gbr膜及其制备方法
CN116173303B (zh) * 2023-04-27 2023-07-04 北赛泓升(北京)生物科技有限公司 一种生物鼓膜及其制备方法和应用

Family Cites Families (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1569707A (en) * 1922-03-29 1926-01-12 Gussie M Bunnell Dumping truck
US1999286A (en) * 1933-07-12 1935-04-30 Bolt Minor T De Brake
FR851651A (fr) * 1938-09-21 1940-01-12 Westinghouse Freins & Signaux Perfectionnements à la fabrication de dispositifs à conductibilité asymétrique
US3361200A (en) * 1965-03-01 1968-01-02 Lawrence S. Chambers Equipment and method for servicing submarine oil wells
US4078564A (en) * 1976-02-24 1978-03-14 Novo Enzyme Corporation Intralenticular cataract surgery
US4223984A (en) * 1979-04-04 1980-09-23 Opticol Corporation Collagen soft contact lens
US4268131A (en) * 1979-04-11 1981-05-19 Opticol Corporation Fiber collagen contact lens
US4581030A (en) * 1982-09-30 1986-04-08 Massachusetts General Hospital Collagen replacement prothesis for the cornea
US4563779A (en) * 1984-01-27 1986-01-14 Kelman Charles D Corneal implant and method of making the same
CA1295796C (en) * 1984-03-27 1992-02-18 Conrad Whyne Biodegradable matrix and methods for producing same
US4600533A (en) * 1984-12-24 1986-07-15 Collagen Corporation Collagen membranes for medical use
AU593010B2 (en) * 1985-08-23 1990-02-01 Washington Research Foundation Polymeric intraocular lens material
US4636210A (en) * 1985-12-09 1987-01-13 Hoffer Kenneth J Multi-part intraocular lens and method of implanting it in an eye
GB2185124B (en) * 1986-01-03 1989-10-25 Choyce David P Intra-corneal implant
US4981841A (en) * 1986-04-04 1991-01-01 Allergan, Inc. Methods and materials for use in corneal wound healing
US4799931A (en) * 1986-05-14 1989-01-24 Lindstrom Richard L Intracorneal lens
US4819617A (en) * 1986-09-04 1989-04-11 University Of Florida Viscoelastic material for ophthalmic surgery
US5114627A (en) * 1986-10-16 1992-05-19 Cbs Lens Method for producing a collagen hydrogel
US5112350A (en) * 1986-10-16 1992-05-12 Cbs Lens, A California General Partnership Method for locating on a cornea an artificial lens fabricated from a collagen-hydrogel for promoting epithelial cell growth and regeneration of the stroma
US4994081A (en) * 1986-10-16 1991-02-19 Cbs Lens Method for locating on a cornea an artificial lens fabricated from a collagen-hydrogel for promoting epithelial cell growth
US4983181A (en) * 1986-10-16 1991-01-08 Cbs Lens, Collagen hydrogel for promoting epithelial cell growth and artificial lens using the same
US4898461A (en) * 1987-06-01 1990-02-06 Valdemar Portney Multifocal ophthalmic lens
US4810082A (en) * 1987-07-01 1989-03-07 Abel Robert Jr Corneal onlay lens
US4834748A (en) * 1987-09-29 1989-05-30 Allergan, Inc. Method and apparatus for removing corneal tissue
US5192316A (en) * 1988-02-16 1993-03-09 Allergan, Inc. Ocular device
US5108428A (en) * 1988-03-02 1992-04-28 Minnesota Mining And Manufacturing Company Corneal implants and manufacture and use thereof
US4923467A (en) * 1988-03-02 1990-05-08 Thompson Keith P Apparatus and process for application and adjustable reprofiling of synthetic lenticules for vision correction
US5104408A (en) * 1988-03-02 1992-04-14 Thompson Keith P Apparatus and process for application and adjustable reprofiling of synthetic lenticules for vision correction
US5614587A (en) * 1988-11-21 1997-03-25 Collagen Corporation Collagen-based bioadhesive compositions
US5936035A (en) * 1988-11-21 1999-08-10 Cohesion Technologies, Inc. Biocompatible adhesive compositions
US5475052A (en) * 1988-11-21 1995-12-12 Collagen Corporation Collagen-synthetic polymer matrices prepared using a multiple step reaction
US5565519A (en) * 1988-11-21 1996-10-15 Collagen Corporation Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications
US5019097A (en) * 1989-11-22 1991-05-28 Allergan, Inc. Corneal onlay lenses and methods for attaching same
US5201764A (en) * 1990-02-28 1993-04-13 Autogenesis Technologies, Inc. Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom
US5196027A (en) * 1990-05-02 1993-03-23 Thompson Keith P Apparatus and process for application and adjustable reprofiling of synthetic lenticules for vision correction
US5288436A (en) * 1990-11-06 1994-02-22 Colloptics, Inc. Methods of fabricating a collagen lenticule precursor for modifying the cornea
US5196026A (en) * 1991-09-16 1993-03-23 Chiron Ophthalmics, Inc. Method of implanting corneal inlay lenses smaller than the optic zone
WO1993014133A1 (en) * 1992-01-15 1993-07-22 Allergan, Inc. Hydrogel compositions and structures made from same
US5292514A (en) * 1992-06-24 1994-03-08 Minnesota Mining And Manufacturing Company Azlactone-functional substrates, corneal prostheses, and manufacture and use thereof
DE69324811T2 (de) * 1992-08-07 1999-09-16 Keravision Inc Intrastromaler kornealring
US5405384A (en) * 1992-09-03 1995-04-11 Keravision, Inc. Astigmatic correcting intrastromal corneal ring
US5300118A (en) * 1992-09-21 1994-04-05 Keravision Adjustable devices for corneal curvature adjustment
US5836313A (en) * 1993-02-08 1998-11-17 Massachusetts Institute Of Technology Methods for making composite hydrogels for corneal prostheses
US5487895A (en) * 1993-08-13 1996-01-30 Vitaphore Corporation Method for forming controlled release polymeric substrate
TW257671B (pt) * 1993-11-19 1995-09-21 Ciba Geigy
US6197019B1 (en) * 1994-04-25 2001-03-06 Gholam A. Peyman Universal implant blank for modifying corneal curvature and methods of modifying corneal curvature therewith
US5496339A (en) * 1994-05-17 1996-03-05 Koepnick; Russell G. Universal automated keratectomy apparatus and method
US5964748A (en) * 1995-10-20 1999-10-12 Peyman; Gholam A. Intrastromal corneal modification
US6221067B1 (en) * 1995-10-20 2001-04-24 Gholam A. Peyman Corneal modification via implantation
US5722971A (en) * 1995-10-20 1998-03-03 Peyman; Gholam A. Intrastromal corneal modification
US5919185A (en) * 1997-04-25 1999-07-06 Peyman; Gholam A. Universal implant blank for modifying corneal curvature and methods of modifying corneal curvature therewith
US6551307B2 (en) * 2001-03-23 2003-04-22 Gholam A. Peyman Vision correction using intrastromal pocket and flap
US6203538B1 (en) * 1995-11-03 2001-03-20 Gholam A. Peyman Intrastromal corneal modification
EP0938903A4 (en) * 1996-02-07 2000-11-15 Rohto Pharma OPHTHALMIC COMPOSITION WITH REGULATED VISCOSITY
WO1997035904A1 (en) * 1996-03-27 1997-10-02 Novartis Ag Process for manufacture of a porous polymer from a mixture
US5733334A (en) * 1996-12-09 1998-03-31 Microoptix Method and apparatus for adjusting corneal curvature
US5876439A (en) * 1996-12-09 1999-03-02 Micooptix, Llc Method and appartus for adjusting corneal curvature using a fluid-filled corneal ring
US6030634A (en) * 1996-12-20 2000-02-29 The Chinese University Of Hong Kong Polymer gel composition and uses therefor
US6186148B1 (en) * 1998-02-04 2001-02-13 Kiyoshi Okada Prevention of posterior capsular opacification
US6036891A (en) * 1998-05-11 2000-03-14 Pharmacia & Upjohn Polymerizable hydrophilic ultraviolet light absorbing monomers
US6599305B1 (en) * 1998-08-12 2003-07-29 Vladimir Feingold Intracorneal lens placement method and apparatus
US6361560B1 (en) * 1998-12-23 2002-03-26 Anamed, Inc. Corneal implant and method of manufacture
WO2000056354A2 (en) * 1999-03-22 2000-09-28 Boston Innovative Optics, Inc. Methods of using agents that act on the epithelial sheet of a human eye
US20020039788A1 (en) * 2000-02-29 2002-04-04 Isseroff Roslyn R. Corneal epithelial graft composites
US20070031473A1 (en) * 2005-08-05 2007-02-08 Peyman Gholam A Drug delivery system and method
US6689165B2 (en) * 2000-03-31 2004-02-10 Board Of Supervisors Of Louisana State University And Agricultural And Mechanical College Surface modifications for enhanced epithelialization
US6717651B2 (en) * 2000-04-12 2004-04-06 Nikon Corporation Exposure apparatus, method for manufacturing thereof and method for manufacturing microdevice
US6338559B1 (en) * 2000-04-28 2002-01-15 University Of Rochester Apparatus and method for improving vision and retinal imaging
US6544286B1 (en) * 2000-07-18 2003-04-08 Tissue Engineering Refraction, Inc. Pre-fabricated corneal tissue lens method of corneal overlay to correct vision
AR030341A1 (es) * 2000-08-14 2003-08-20 Novartis Ag Articulos biomedicos moldeados
US7152975B2 (en) * 2000-11-10 2006-12-26 Cooper Vision, Inc. Junctionless ophthalmic lenses and methods for making same
US6547391B2 (en) * 2000-12-08 2003-04-15 Johnson & Johnson Vision Care, Inc. Ocular aberration correction taking into account fluctuations due to biophysical rhythms
RU2190841C1 (ru) * 2001-07-04 2002-10-10 Общество с ограниченной ответственностью "Научно-экспериментальное производство Микрохирургия глаза" Биосовместимый оптически прозрачный полимерный материал
US7156859B2 (en) * 2001-07-23 2007-01-02 Fos Holding S.A. Device for separating the epithelium layer from the surface of the cornea of an eye
US6702807B2 (en) * 2001-09-10 2004-03-09 Minu, L.L.C. Ablatable intracorneal inlay with predetermined refractive properties
US6860601B2 (en) * 2002-02-06 2005-03-01 John H. Shadduck Adaptive optic lens system and method of use
US7476398B1 (en) * 2002-06-28 2009-01-13 Universite Laval Corneal implant and uses thereof
US6855163B2 (en) * 2002-07-19 2005-02-15 Minu, Llc Gradual correction of corneal refractive error using multiple inlays
AU2003254677A1 (en) * 2002-08-09 2004-02-25 Ottawa Health Research Institute Innervated artificial tissues and uses thereof
CN100491424C (zh) * 2002-08-09 2009-05-27 渥太华健康研究所 生物-合成基质及其用途
US7235195B2 (en) * 2002-09-06 2007-06-26 Novartis Ag Method for making opthalmic devices
BR0314266A (pt) * 2002-09-13 2005-07-26 Ocular Sciences Inc Dispositivos e métodos para a melhora de visão
US7166118B2 (en) * 2002-11-27 2007-01-23 Bausch & Lomb Incorporated Microkeratome blade assembly
US7186266B2 (en) * 2003-06-06 2007-03-06 Teledioptic Lens System, Llc Bifocal intraocular telescope for low vision correction
US7927519B2 (en) * 2003-07-30 2011-04-19 Eyesense Ag Reflection hologram sensor in contact lens
US20070016292A1 (en) * 2003-11-14 2007-01-18 Edward Perez Epithelium treatment methods and devices for treating the epithelium
AU2004296710B2 (en) * 2003-11-19 2009-08-27 Vision Crc Limited Methods and apparatuses for altering relative curvature of field and positions of peripheral, off-axis focal positions
BRPI0510477B1 (pt) * 2004-04-28 2023-01-17 Angiotech Biomaterials Corporation Método para formar um gel e dispositivo para uso em aplicações médicas
MXPA06013343A (es) * 2004-05-20 2007-05-08 Coopervision Inc Injertos corneos y correccion de aberracion de frente de ondas para mejorar la vision.
JP2008508959A (ja) * 2004-08-13 2008-03-27 オタワ ヘルス リサーチ インスティテュート 眼用器具及び関連した方法及び組成物
US20060064112A1 (en) * 2004-09-08 2006-03-23 Edward Perez Ocular device applicator
US20060052796A1 (en) * 2004-09-08 2006-03-09 Edward Perez Combined epithelial delaminator and inserter
US20060071356A1 (en) * 2004-10-04 2006-04-06 Kevin Beebe Method for separating excess material from a lens mold
US7857849B2 (en) * 2004-10-05 2010-12-28 The Board Of Trustees Of The Leland Stanford Junior Iniversity Artificial corneal implant
CA2548881A1 (en) * 2005-05-27 2006-11-27 University Of Ottawa Neoglycopolymer-cross-linked biopolymer matrix
US7520608B2 (en) * 2006-03-20 2009-04-21 High Performance Optics, Inc. Color balanced ophthalmic system with selective light inhibition
MX2009008829A (es) * 2007-02-23 2011-10-28 Pixeloptics Inc Apertura dinamica oftalmica.
KR101572634B1 (ko) * 2008-04-04 2015-12-01 포사이트 비젼4, 인크. 통증 관리 및 시력을 위한 치료 장치
US20100087920A1 (en) * 2008-10-07 2010-04-08 Forsight Labs, Llc Corneal Onlay Lenses and Related Methods for Improving Vision of Presbyopic Patients

Also Published As

Publication number Publication date
WO2006020859A3 (en) 2007-01-25
CA2576308C (en) 2015-06-30
CN101018513A (zh) 2007-08-15
CA2576308A1 (en) 2006-02-16
EP1776148B1 (en) 2019-03-06
JP2008509748A (ja) 2008-04-03
KR20070053217A (ko) 2007-05-23
CA2577025A1 (en) 2006-02-23
US20060134170A1 (en) 2006-06-22
CA2577025C (en) 2014-01-28
TWI388349B (zh) 2013-03-11
EP1776148A1 (en) 2007-04-25
KR20070060077A (ko) 2007-06-12
CN101018513B (zh) 2011-11-16
JP2008508959A (ja) 2008-03-27
EP1776148A4 (en) 2011-08-17
TW200618824A (en) 2006-06-16
TWI288630B (en) 2007-10-21
EP1791499A4 (en) 2011-08-17
JP2011020001A (ja) 2011-02-03
TW200628133A (en) 2006-08-16
US20080269119A1 (en) 2008-10-30
CN101132818A (zh) 2008-02-27
WO2006015490A1 (en) 2006-02-16
EP1791499A2 (en) 2007-06-06
WO2006020859A2 (en) 2006-02-23
KR101298442B1 (ko) 2013-08-22

Similar Documents

Publication Publication Date Title
BRPI0514349A (pt) dispositivos oftálmicos para o reforço da visão e métodos e composições relacionadas
O’Brart Corneal collagen cross-linking: a review
IL176397A (en) Pharmaceutical compositions containing hyaluronidase or collagenase for treatment of ophthalmic conditions
El-Anwar et al. Transconjunctival versus subciliary approach to the infraorbital margin for open reduction of zygomaticomaxillary complex fractures: a randomized feasibility study
CN104921983A (zh) 一种孕妇妊娠纹医用生物修复敷料及其制备方法
CN108904633A (zh) 一种改善视力的眼膏及其制备方法
Glaser Treatment of trigeminal neuralgia with trichlorethylene
EHRENFRIED Reverdin and other methods of skin-grafting: historical
KR20160077272A (ko) Led를 이용한 안구 피로회복 장치
ES2863726T3 (es) Hidrogel de poliacrilamida para su uso en la prevención y/o el tratamiento de la sinovitis en un mamífero
EP3419590B1 (en) Hyaluronic acid conjugate
Beigi et al. Lower eyelid excursion: a functional and cosmetically relevant parameter in the treatment of lower eyelid retraction
Liu et al. Prevention effect of medical self-crosslinking sodium hyaluronate gel on epidural scar adhesion after laminectomy
Caruso et al. Use of subdermal hyaluronic acid injections and a free labial mucocutaneous graft for the repair of feline eyelid agenesis
CN107551090A (zh) 一种滋养修复凝胶
CN1234227A (zh) 含生物高能修护因子的美容组合物及其应用
Lee et al. Hyaluronic acid filler injection as an alternative to surgery for the correction of canine entropion.
Zhang et al. Lower lid ectropion in hypohidrotic ectodermal dysplasia
Eserdağ Hyaluronic Acid Applications to Genital Area
FISKE CHICAGO LARYNGOLOGICAL AND OTOLOGICAL SOCIETY: Regular Meeting, Jan. 9, 1928
Yavana Rani An Observational study on Extended Excision of Pterygium with Sutureless and Glueless Conjunctival Autograft in Pterygium Surgery
RU2126235C1 (ru) Способ лечения повреждений и заболеваний роговицы глаза
Blanco-Moredo et al. Lipotransfer: An alternative for the treatment of acquired facial de-formity
Yoshino et al. Residual amounts of ophthalmic viscosurgical devices on the corneal endothelium following phacoemulsification
Bellary et al. The Charcot foot

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]