NO753009L - - Google Patents

Info

Publication number
NO753009L
NO753009L NO753009A NO753009A NO753009L NO 753009 L NO753009 L NO 753009L NO 753009 A NO753009 A NO 753009A NO 753009 A NO753009 A NO 753009A NO 753009 L NO753009 L NO 753009L
Authority
NO
Norway
Application number
NO753009A
Other languages
Norwegian (no)
Other versions
NO144216C (no
NO144216B (no
Inventor
H J Schaeffer
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10402412&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO753009(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of NO753009L publication Critical patent/NO753009L/no
Publication of NO144216B publication Critical patent/NO144216B/no
Publication of NO144216C publication Critical patent/NO144216C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO753009A 1974-09-02 1975-09-02 Analogifremgangsmaate til fremstilling av terapeutisk virksomme purinforbindelser og salter derav NO144216C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB38278/74A GB1523865A (en) 1974-09-02 1974-09-02 Purine compunds and salts thereof

Publications (3)

Publication Number Publication Date
NO753009L true NO753009L (da) 1976-03-03
NO144216B NO144216B (no) 1981-04-06
NO144216C NO144216C (no) 1981-07-15

Family

ID=10402412

Family Applications (1)

Application Number Title Priority Date Filing Date
NO753009A NO144216C (no) 1974-09-02 1975-09-02 Analogifremgangsmaate til fremstilling av terapeutisk virksomme purinforbindelser og salter derav

Country Status (35)

Country Link
US (3) US4360522A (da)
JP (1) JPS5154589A (da)
AR (4) AR220299A1 (da)
AT (1) AT354462B (da)
AU (1) AU503160B2 (da)
BE (1) BE833006A (da)
BG (4) BG25094A3 (da)
CA (1) CA1062257A (da)
CH (7) CH626363A5 (da)
CS (2) CS203092B2 (da)
CY (1) CY1033A (da)
DD (1) DD122092A5 (da)
DE (1) DE2539963C2 (da)
DK (1) DK146595C (da)
ES (3) ES440631A1 (da)
FI (1) FI60709C (da)
FR (1) FR2282892A1 (da)
GB (1) GB1523865A (da)
HK (1) HK84379A (da)
HU (1) HU176730B (da)
IE (1) IE42282B1 (da)
IL (1) IL48035A (da)
KE (1) KE3002A (da)
LU (1) LU73304A1 (da)
MC (1) MC1068A1 (da)
MY (1) MY8200191A (da)
NL (1) NL175061C (da)
NO (1) NO144216C (da)
NZ (1) NZ178556A (da)
RO (4) RO74274A (da)
SE (1) SE428562C (da)
SU (7) SU904523A3 (da)
YU (4) YU39947B (da)
ZA (1) ZA755574B (da)
ZM (1) ZM12875A1 (da)

Families Citing this family (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146715A (en) 1975-08-27 1979-03-27 Burroughs Wellcome Co. 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines
US4060616A (en) * 1976-03-01 1977-11-29 Burroughs Wellcome Co. Purine derivatives with repeating unit
US4287188A (en) 1977-02-24 1981-09-01 Burroughs Wellcome Co. Purine derivatives
AU521577B2 (en) * 1977-02-24 1982-04-22 Wellcome Foundation Limited, The 9-hydroxyethoxymethyl guanine phosphates
KR830005852A (ko) * 1980-07-18 1983-09-14 미첼 페터 잭슨 피부와 점막의 비루스 감염치료에 적합한 국소치료제의 제조방법
US5157120A (en) * 1980-09-16 1992-10-20 Syntex (U.S.A.) Inc. Guanine derivatives
US4347360A (en) * 1980-09-16 1982-08-31 Ens Bio Logicals Inc. Ring open nucleoside analogues
JPS57102818A (en) * 1980-10-15 1982-06-26 Wellcome Found Treatment for fish virus diseases
US4355032B2 (en) * 1981-05-21 1990-10-30 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent
US4423050A (en) * 1981-05-21 1983-12-27 Syntex (U.S.A.) Inc. 9-(1,3-Dihydroxy-2-propoxymethyl)guanine as antiviral agent
US4603219A (en) * 1981-05-21 1986-07-29 Syntex (U.S.A.) Inc. 1,3-dibenzyloxy-2-acetoxymethoxypropane, intermediate for 9-(1,3-dihydroxy-2-propoxymethyl)guanine
KR880002276B1 (ko) * 1981-08-11 1988-10-21 더 웰컴 화운데이션 리미티드 항비루스성 화합물의 제조방법
AU564576B2 (en) * 1981-09-24 1987-08-20 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Purine derivatives
US5250535A (en) * 1982-02-01 1993-10-05 Syntex Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
JPS59500317A (ja) * 1982-02-12 1984-03-01 シンテツクス　（ユー・エス・エイ）　インコーポレイテツド 抗ウイルス性組成物
SE8203855D0 (sv) * 1982-06-21 1982-06-21 Astra Laekemedel Ab Novel derivatives of guanine i
SE8203856D0 (sv) * 1982-06-21 1982-06-21 Astra Laekemedel Ab Novel derivatives of guanine ii
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
DE3376325D1 (en) * 1982-10-14 1988-05-26 Wellcome Found Antiviral purine derivatives
US4745119A (en) * 1982-10-14 1988-05-17 Burroughs Wellcome Co. Method for using purine derivatives
US5059604A (en) * 1982-10-14 1991-10-22 Burroughs Wellcome Co. 2-amino purine derivatives
US4649140A (en) * 1982-10-14 1987-03-10 Burroughs Wellcome Co. Purine derivatives
US4609662A (en) * 1982-10-14 1986-09-02 Burroughs Wellcome Co. Method for using purine derivatives
US4612314A (en) * 1982-12-22 1986-09-16 Syntex (U.S.A.) Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
US4461757A (en) * 1983-02-23 1984-07-24 Ens Bio Logicals Inc. Dimethylaminomethylenated anti-herpes compounds
ES520140A0 (es) * 1983-02-25 1984-04-01 Ind Farma Especial Un procedimiento para la preparacion de acicloguanosina.
US5047533A (en) * 1983-05-24 1991-09-10 Sri International Acyclic purine phosphonate nucleotide analogs
US4557934A (en) 1983-06-21 1985-12-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one
JPS6023380A (ja) * 1983-06-24 1985-02-05 メルク・エンド・カムパニー・インコーポレーテッド 抗ウイルス剤
US4880820A (en) * 1983-06-24 1989-11-14 Merck & Co., Inc. Guanine derivatives
US5684153A (en) * 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
US4897479A (en) * 1983-09-30 1990-01-30 Merck & Co., Inc. Arylsulfonyloxy purine intermediates
JPS6094992A (ja) * 1983-10-28 1985-05-28 Sankyo Co Ltd グリゼオ−ル酸誘導体
US4918219A (en) * 1983-10-31 1990-04-17 Warner-Lambert Company Glycerine derivatives
US4806642A (en) * 1984-10-05 1989-02-21 Warner-Lambert Company Purine derivatives
ZA848080B (en) * 1983-10-31 1985-06-26 Warner Lambert Co Purine derivatives
IE842642L (en) * 1983-10-31 1985-04-30 Harvard College Purine Derivatives
US4579849A (en) * 1984-04-06 1986-04-01 Merck & Co., Inc. N-alkylguanine acyclonucleosides as antiviral agents
US4617304A (en) * 1984-04-10 1986-10-14 Merck & Co., Inc. Purine derivatives
DK163985A (da) * 1984-04-13 1985-10-14 Wellcome Found Antivirale purinderivater, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne
US4636507A (en) * 1984-04-30 1987-01-13 Hoechst-Roussel Pharmaceuticals Inc. Host defense mechanism enhancement
EP0167385B1 (en) 1984-07-03 1992-03-18 The Wellcome Foundation Limited Antiviral compounds, treatment and formulations
WO1986000901A1 (en) * 1984-07-20 1986-02-13 Gauntt Charles O Immunoregulatory and anti-viral compound
SE8406538D0 (sv) * 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
US5683990A (en) * 1985-03-16 1997-11-04 Glaxo Wellcome Inc. Treatment of human viral infections
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
CS263951B1 (en) * 1985-04-25 1989-05-12 Antonin Holy 9-(phosponylmethoxyalkyl)adenines and method of their preparation
CS263952B1 (en) * 1985-04-25 1989-05-12 Holy Antonin Remedy with antiviral effect
EP0203736B1 (en) 1985-05-02 1989-11-23 The Wellcome Foundation Limited Antiviral compounds
IL78643A0 (en) * 1985-05-02 1986-08-31 Wellcome Found Purine derivatives,their preparation and pharmaceutical compositions containing them
DE3529497A1 (de) * 1985-08-17 1987-02-26 Boehringer Mannheim Gmbh N(pfeil hoch)6(pfeil hoch)-disubstituierte purinderivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE3627024A1 (de) * 1985-09-24 1987-04-02 Hoechst Ag In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine
IT1207507B (it) * 1985-10-21 1989-05-25 Baldacci Lab Spa Coniugato della 9-(2-idrossietossimetil)guanina con albumina umana lattosaminata, procedimento per la sua preparazione e composizioni farmaceutiche che la contengono.
AU618723B2 (en) * 1986-10-06 1992-01-09 University Of Virginia Alumni Patents Foundation, The Use of an adenosine, hypoxanthine and ribose-containing solution for improved protection of the heart during surgery
EP0290630A4 (de) * 1986-11-25 1990-02-26 Inst Organicheskogo Sinteza Ak 9-substituierte guanine.
US4978655A (en) * 1986-12-17 1990-12-18 Yale University Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with retroviruses
US4829055A (en) * 1987-01-23 1989-05-09 Naficy Sadeque S Method of treatment for herpes infections of external tissues
US5565566A (en) * 1987-04-24 1996-10-15 Discovery Therapeutics, Inc. N6 -substituted 9-methyladenines: a new class of adenosine receptor antagonists
US4835104A (en) * 1987-06-16 1989-05-30 Ajinomoto Co., Inc., Patent & Licensing Department Process for producing and purifying 2',3'-dideoxynucleosides, and process for producing 2',3'-dideoxy-2',3'-didehydronucleosides
US6306647B1 (en) 1987-06-16 2001-10-23 Ajinomoto Co., Inc. Process for producing and purifying 2′,3′-dideoxynucleosides, and process for producing 2′,3′-dideoxy-2′,3′-didehydronucleosides
GB8725939D0 (en) * 1987-11-05 1987-12-09 Wellcome Found Therapeutic compounds
GB8719367D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Therapeutic compounds
CA1302887C (en) * 1987-11-24 1992-06-09 Yves Langelier Combination of acyclovir or a derivative thereof and bacitracin
JPH01121424U (da) * 1988-02-10 1989-08-17
GB8815241D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Antiviral combinations & compounds therefor
US5164395A (en) * 1988-06-27 1992-11-17 Burroughs Wellcome Co. Antiviral acetyl pyridine derivative or said acetyl pyridine derivative in combination with acyclovir
GB8816760D0 (en) * 1988-07-14 1988-08-17 Wellcome Found Therapeutic compounds
EP0366385B1 (en) * 1988-10-24 1993-06-09 The Wellcome Foundation Limited Guanine derivatives having antiviral activity and their pharmaceutically acceptable salts
WO1990009178A1 (en) * 1989-01-31 1990-08-23 Whitby Research, Inc. N6-substituted 9-methyladenines: a new class of adenosine receptor antagonists
US4966895A (en) * 1989-02-02 1990-10-30 Merck & Co. Inc. Cyclic monophosphates of purine and pyrimidine acyclonucleosides as anti-retroviral agents
GB8907173D0 (en) * 1989-03-30 1989-05-10 Beecham Group Plc Novel compounds
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US5879700A (en) * 1991-10-15 1999-03-09 Hostetler; Karl Y. Nucleoside analogue phosphates for topical use
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US5654286A (en) * 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
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US5567816A (en) * 1994-07-26 1996-10-22 Syntex (U.S.A.) Inc. Preparation of acyclovir using 1,3 dioxolane
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US5856481A (en) * 1994-07-28 1999-01-05 Syntex (U.S.A.) Inc. 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
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US5627185A (en) * 1994-11-23 1997-05-06 Gosselin; Gilles Acyclovir derivatives as antiviral agents
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US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
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AR074897A1 (es) 2008-12-23 2011-02-23 Pharmasset Inc Fosforamidatos de nucleosidos
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Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
US4146715A (en) * 1975-08-27 1979-03-27 Burroughs Wellcome Co. 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines

Also Published As

Publication number Publication date
MC1068A1 (fr) 1976-05-21
DK392675A (da) 1976-03-03
DK146595B (da) 1983-11-14
RO74275A (ro) 1981-09-24
SU784777A3 (ru) 1980-11-30
FI60709B (fi) 1981-11-30
AR220885A1 (es) 1980-12-15
DE2539963C2 (de) 1987-01-22
YU40080B (en) 1985-06-30
BG24815A3 (en) 1978-05-12
NZ178556A (en) 1978-09-25
IL48035A0 (en) 1975-11-25
JPS6147839B2 (da) 1986-10-21
ATA676375A (de) 1979-06-15
SU904523A3 (ru) 1982-02-07
NL175061C (nl) 1984-09-17
SU751325A3 (ru) 1980-07-23
YU120082A (en) 1982-08-31
IE42282L (en) 1976-03-02
CH623587A5 (da) 1981-06-15
DD122092A5 (da) 1976-09-12
CA1062257A (en) 1979-09-11
SU799664A3 (ru) 1981-01-23
SE428562B (sv) 1983-07-11
KE3002A (en) 1979-12-14
ES455979A1 (es) 1978-01-16
FI752465A (da) 1976-03-03
CH626364A5 (da) 1981-11-13
ZA755574B (en) 1977-04-27
NO144216C (no) 1981-07-15
FI60709C (fi) 1982-03-10
HU176730B (en) 1981-04-28
SU700064A3 (ru) 1979-11-25
MY8200191A (en) 1982-12-31
RO74276A (ro) 1981-06-26
YU120182A (en) 1982-08-31
AR220299A1 (es) 1980-10-31
CH629805A5 (de) 1982-05-14
RO74274A (ro) 1981-09-24
SU686618A3 (ru) 1979-09-15
FR2282892A1 (fr) 1976-03-26
YU39947B (en) 1985-06-30
SU858569A3 (ru) 1981-08-23
RO76939A (ro) 1981-06-22
CH626363A5 (da) 1981-11-13
IL48035A (en) 1981-07-31
CH629206A5 (de) 1982-04-15
BE833006A (fr) 1976-03-02
NL175061B (nl) 1984-04-16
LU73304A1 (da) 1976-08-13
US4323573A (en) 1982-04-06
AU8445975A (en) 1977-03-10
YU119982A (en) 1982-08-31
CS203092B2 (en) 1981-02-27
AR220508A1 (es) 1980-11-14
ZM12875A1 (en) 1977-09-21
SE428562C (sv) 1985-11-18
CH623586A5 (da) 1981-06-15
CS203093B2 (en) 1981-02-27
ES440631A1 (es) 1977-06-16
AU503160B2 (en) 1979-08-23
AT354462B (de) 1979-01-10
YU222075A (en) 1982-08-31
CH628897A5 (de) 1982-03-31
BG26536A4 (bg) 1979-04-12
ES455978A1 (es) 1978-01-16
FR2282892B1 (da) 1980-04-25
BG26389A3 (bg) 1979-03-15
YU40079B (en) 1985-06-30
AR212914A1 (es) 1978-11-15
US4294831A (en) 1981-10-13
CY1033A (en) 1980-08-01
US4360522A (en) 1982-11-23
SE7509675L (sv) 1976-03-03
IE42282B1 (en) 1980-07-16
DK146595C (da) 1984-04-24
GB1523865A (en) 1978-09-06
NO144216B (no) 1981-04-06
HK84379A (en) 1979-12-14
BG25094A3 (en) 1978-07-12
JPS5154589A (en) 1976-05-13
NL7510342A (nl) 1976-03-04
DE2539963A1 (de) 1976-03-18

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