NO331382B1 - Farmasoytisk formulering som omfatter eksendin-4. - Google Patents
Farmasoytisk formulering som omfatter eksendin-4. Download PDFInfo
- Publication number
- NO331382B1 NO331382B1 NO20013468A NO20013468A NO331382B1 NO 331382 B1 NO331382 B1 NO 331382B1 NO 20013468 A NO20013468 A NO 20013468A NO 20013468 A NO20013468 A NO 20013468A NO 331382 B1 NO331382 B1 NO 331382B1
- Authority
- NO
- Norway
- Prior art keywords
- exendin
- glucose
- glp
- plasma
- dose
- Prior art date
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- 108010011459 Exenatide Proteins 0.000 title claims description 181
- 229960001519 exenatide Drugs 0.000 title claims description 181
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11638099P | 1999-01-14 | 1999-01-14 | |
| US17536500P | 2000-01-10 | 2000-01-10 | |
| PCT/US2000/000902 WO2000041546A2 (en) | 1999-01-14 | 2000-01-14 | Novel exendin agonist formulations and methods of administration thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20013468D0 NO20013468D0 (no) | 2001-07-12 |
| NO20013468L NO20013468L (no) | 2001-09-14 |
| NO331382B1 true NO331382B1 (no) | 2011-12-12 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20013468A NO331382B1 (no) | 1999-01-14 | 2001-07-12 | Farmasoytisk formulering som omfatter eksendin-4. |
| NO2012008C NO2012008I1 (no) | 1999-01-14 | 2012-05-09 | Eksenatid/eksendin-4 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO2012008C NO2012008I1 (no) | 1999-01-14 | 2012-05-09 | Eksenatid/eksendin-4 |
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| US (1) | US6902744B1 (ko) |
| EP (2) | EP1609478A1 (ko) |
| JP (1) | JP4426727B2 (ko) |
| KR (1) | KR100675711B1 (ko) |
| CN (2) | CN100356978C (ko) |
| AT (1) | ATE299031T2 (ko) |
| AU (2) | AU777564B2 (ko) |
| BR (1) | BRPI0007820B8 (ko) |
| CA (1) | CA2356706C (ko) |
| CY (1) | CY2007013I1 (ko) |
| DE (3) | DE122007000001I1 (ko) |
| DK (1) | DK1140145T4 (ko) |
| ES (1) | ES2244416T5 (ko) |
| HK (1) | HK1040635B (ko) |
| LU (1) | LU91343I2 (ko) |
| NL (1) | NL300282I1 (ko) |
| NO (2) | NO331382B1 (ko) |
| NZ (1) | NZ512663A (ko) |
| PT (1) | PT1140145E (ko) |
| RU (1) | RU2242244C2 (ko) |
| WO (1) | WO2000041546A2 (ko) |
Families Citing this family (145)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US6858576B1 (en) * | 1996-08-08 | 2005-02-22 | Amylin Pharmaceuticals, Inc. | Methods for regulating gastrointestinal motility |
| CA2277112C (en) * | 1997-01-07 | 2008-08-26 | Amylin Pharmaceuticals, Inc. | Use of exendins and agonists thereof for the reduction of food intake |
| US20030087820A1 (en) * | 1999-01-14 | 2003-05-08 | Young Andrew A. | Novel exendin agonist formulations and methods of administration thereof |
| NZ512657A (en) | 1999-01-14 | 2004-01-30 | Amylin Pharmaceuticals Inc | Glucagon suppression |
| US7399489B2 (en) | 1999-01-14 | 2008-07-15 | Amylin Pharmaceuticals, Inc. | Exendin analog formulations |
| US20090175821A1 (en) * | 1999-05-17 | 2009-07-09 | Bridon Dominique P | Modified therapeutic peptides with extended half-lives in vivo |
| US6514500B1 (en) * | 1999-10-15 | 2003-02-04 | Conjuchem, Inc. | Long lasting synthetic glucagon like peptide {GLP-!} |
| US6528486B1 (en) | 1999-07-12 | 2003-03-04 | Zealand Pharma A/S | Peptide agonists of GLP-1 activity |
| US7022674B2 (en) | 1999-12-16 | 2006-04-04 | Eli Lilly And Company | Polypeptide compositions with improved stability |
| US7090869B2 (en) | 2000-12-01 | 2006-08-15 | Takeda Pharmaceutical Company Limited | Method for producing preparation containing bioactive substance |
| DK1412384T3 (da) | 2001-06-28 | 2008-04-28 | Novo Nordisk As | Stabil formulering af modificeret GLP-1 |
| DE60228972D1 (de) * | 2001-07-31 | 2008-10-30 | Us Gov Health & Human Serv | Glp 1 exendin 4 peptidanaloga und deren verwendungen |
| EP1572892A4 (en) * | 2001-10-18 | 2007-08-22 | Bristol Myers Squibb Co | HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS |
| DE10238931C1 (de) * | 2002-08-24 | 2003-07-31 | Fh Hildesheim Holzminden Goe | Verfahren und Vorrichtung zur Vorbereitung eines Finger- oder Fußnagels für eine Beschichtung, insbesondere Lackierung |
| JP2006506386A (ja) * | 2002-10-22 | 2006-02-23 | ワラタ ファーマシューティカルズ， インコーポレイテッド | 糖尿病の処置 |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| CN1771080B (zh) | 2003-04-08 | 2010-12-15 | 诺沃挪第克公司 | 包括至少一个色谱处理步骤的生产治疗用多肽或其前体的方法 |
| WO2004089985A1 (en) | 2003-04-11 | 2004-10-21 | Novo Nordisk A/S | Stable pharmaceutical compositions |
| US8008255B2 (en) | 2003-05-30 | 2011-08-30 | Amylin Pharmaceuticals, Inc. | Methods and compositions for enhanced transmucosal delivery of peptides and proteins |
| EP2292253A3 (en) | 2003-06-03 | 2011-12-14 | Novo Nordisk A/S | Stabilized pharmaceutical peptide compositions |
| EP2292254A3 (en) | 2003-06-03 | 2011-12-14 | Novo Nordisk A/S | Stabilized pharmaceutical peptide compositions |
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| JP4677095B2 (ja) | 1998-02-13 | 2011-04-27 | アミリン・ファーマシューティカルズ，インコーポレイテッド | エキセンジンおよびｇｌｐ−１の変力および利尿効果 |
| EP1056775B1 (en) * | 1998-02-27 | 2010-04-28 | Novo Nordisk A/S | Glp-1 derivatives of glp-1 and exendin with protracted profile of action |
| US6506724B1 (en) * | 1999-06-01 | 2003-01-14 | Amylin Pharmaceuticals, Inc. | Use of exendins and agonists thereof for the treatment of gestational diabetes mellitus |
| US6528486B1 (en) * | 1999-07-12 | 2003-03-04 | Zealand Pharma A/S | Peptide agonists of GLP-1 activity |
-
2000
- 2000-01-14 CN CNB008048479A patent/CN100356978C/zh not_active Expired - Lifetime
- 2000-01-14 DE DE2000621166 patent/DE122007000001I1/de active Pending
- 2000-01-14 AT AT00914425T patent/ATE299031T2/de active
- 2000-01-14 EP EP05009873A patent/EP1609478A1/en not_active Withdrawn
- 2000-01-14 DK DK00914425.4T patent/DK1140145T4/da active
- 2000-01-14 DE DE60021166.5T patent/DE60021166T3/de not_active Expired - Lifetime
- 2000-01-14 NZ NZ512663A patent/NZ512663A/en not_active IP Right Cessation
- 2000-01-14 CA CA2356706A patent/CA2356706C/en not_active Expired - Lifetime
- 2000-01-14 DE DE122007000042C patent/DE122007000042I2/de active Active
- 2000-01-14 CN CNA2007101658564A patent/CN101181236A/zh active Pending
- 2000-01-14 ES ES00914425T patent/ES2244416T5/es not_active Expired - Lifetime
- 2000-01-14 BR BRPI0007820A patent/BRPI0007820B8/pt not_active IP Right Cessation
- 2000-01-14 AU AU35819/00A patent/AU777564B2/en not_active Expired
- 2000-01-14 US US09/889,330 patent/US6902744B1/en not_active Expired - Lifetime
- 2000-01-14 KR KR1020017008904A patent/KR100675711B1/ko active IP Right Grant
- 2000-01-14 RU RU2001122722/15A patent/RU2242244C2/ru active Protection Beyond IP Right Term
- 2000-01-14 JP JP2000593167A patent/JP4426727B2/ja not_active Expired - Lifetime
- 2000-01-14 EP EP00914425.4A patent/EP1140145B2/en not_active Expired - Lifetime
- 2000-01-14 PT PT00914425T patent/PT1140145E/pt unknown
- 2000-01-14 WO PCT/US2000/000902 patent/WO2000041546A2/en active IP Right Grant
-
2001
- 2001-07-12 NO NO20013468A patent/NO331382B1/no not_active IP Right Cessation
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2002
- 2002-03-27 HK HK02102346.5A patent/HK1040635B/zh not_active IP Right Cessation
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2005
- 2005-01-17 AU AU2005200206A patent/AU2005200206B2/en not_active Expired
-
2007
- 2007-05-18 NL NL300282C patent/NL300282I1/nl unknown
- 2007-05-18 CY CY2007013C patent/CY2007013I1/el unknown
- 2007-05-18 LU LU91343C patent/LU91343I2/fr unknown
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2012
- 2012-05-09 NO NO2012008C patent/NO2012008I1/no unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997046584A1 (de) * | 1996-06-05 | 1997-12-11 | Boehringer Mannheim Gmbh | Exendin-analoga, verfahren zu deren herstellung und diese enthaltende arzneimittel |
| WO1998030231A1 (en) * | 1997-01-07 | 1998-07-16 | Amylin Pharmaceuticals, Inc. | Use of exendins and agonists thereof for the reduction of food intake |
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