NO330521B1 - Substituerte etynylfenyl-1,8-naftyridin-4(1H)-on-forbindelser som er fosfodiesterase-4-inhibitorer, farmasoytiske preparater som omfatter forbindelsene, samt anvendelse av forbindelsene ved fremstilling av medikamenter - Google Patents

Info

Publication number

NO330521B1

NO330521B1 NO20041293A NO20041293A NO330521B1 NO 330521 B1 NO330521 B1 NO 330521B1 NO 20041293 A NO20041293 A NO 20041293A NO 20041293 A NO20041293 A NO 20041293A NO 330521 B1 NO330521 B1 NO 330521B1

Authority

NO

Norway

Prior art keywords

dihydro

carboxamide

phenyl

naphthyridin

isopropyl

Prior art date

2001-08-29

Links

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• 150000003839 salts Chemical class 0.000 claims description 42
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• 230000001154 acute effect Effects 0.000 claims description 24
• 238000002360 preparation method Methods 0.000 claims description 22
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• 208000011580 syndromic disease Diseases 0.000 claims description 19
• 230000000694 effects Effects 0.000 claims description 16
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• 150000002367 halogens Chemical group 0.000 claims description 9
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• HSSSJVUGQHOHQN-UHFFFAOYSA-N 4-oxo-n-propan-2-yl-1-[3-[4,4,4-trifluoro-3-hydroxy-3-(trifluoromethyl)but-1-ynyl]phenyl]-1,8-naphthyridine-3-carboxamide Chemical compound C12=NC=CC=C2C(=O)C(C(=O)NC(C)C)=CN1C1=CC=CC(C#CC(O)(C(F)(F)F)C(F)(F)F)=C1 HSSSJVUGQHOHQN-UHFFFAOYSA-N 0.000 claims description 3
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