EA200400361A1 - Производные алкинарилнафтиридин-4(1h)-онов в качестве ингибитора фосфодиэстеразы типа iv - Google Patents

Производные алкинарилнафтиридин-4(1h)-онов в качестве ингибитора фосфодиэстеразы типа iv

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Publication number
EA200400361A1
EA200400361A1 EA200400361A EA200400361A EA200400361A1 EA 200400361 A1 EA200400361 A1 EA 200400361A1 EA 200400361 A EA200400361 A EA 200400361A EA 200400361 A EA200400361 A EA 200400361A EA 200400361 A1 EA200400361 A1 EA 200400361A1
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EA
Eurasian Patent Office
Prior art keywords
phosphodyesterase
alkinarilnafthyridin
inhibitor
ones
derivatives
Prior art date
Application number
EA200400361A
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English (en)
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EA006800B1 (ru
Inventor
Даниель Гай
Марио Жирар
Пьер Амель
Себастьен Лалиберте
Ришар Фриезен
Original Assignee
Мерк Фросст Кэнада Энд Ко.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Мерк Фросст Кэнада Энд Ко. filed Critical Мерк Фросст Кэнада Энд Ко.
Publication of EA200400361A1 publication Critical patent/EA200400361A1/ru
Publication of EA006800B1 publication Critical patent/EA006800B1/ru

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Abstract

Соединения, представленные формулой (I), или их фармацевтически приемлемые соли, являются ингибиторами фосфодиэстеразы-4, полезными при лечении астмы и воспаления.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200400361A 2001-08-29 2002-08-27 Производные алкинарилнафтиридин-4(1h)-онов в качестве ингибитора фосфодиэстеразы типа iv EA006800B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31609301P 2001-08-29 2001-08-29
PCT/CA2002/001324 WO2003018579A1 (en) 2001-08-29 2002-08-27 Alkyne-aryl phosphodiesterase-4 inhibitors

Publications (2)

Publication Number Publication Date
EA200400361A1 true EA200400361A1 (ru) 2004-08-26
EA006800B1 EA006800B1 (ru) 2006-04-28

Family

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EA200400361A EA006800B1 (ru) 2001-08-29 2002-08-27 Производные алкинарилнафтиридин-4(1h)-онов в качестве ингибитора фосфодиэстеразы типа iv

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US (2) US6743802B2 (ru)
EP (2) EP2305677A1 (ru)
JP (1) JP4157035B2 (ru)
KR (1) KR100928849B1 (ru)
CN (1) CN100338061C (ru)
AR (1) AR036365A1 (ru)
AU (1) AU2002322940B2 (ru)
BR (1) BR0212042A (ru)
CA (1) CA2456817C (ru)
DO (1) DOP2002000456A (ru)
EA (1) EA006800B1 (ru)
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GE (1) GEP20063805B (ru)
HK (1) HK1080073B (ru)
HR (1) HRP20040151A2 (ru)
HU (1) HUP0401729A3 (ru)
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JO (1) JO2311B1 (ru)
MX (1) MXPA04001889A (ru)
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NZ (1) NZ530931A (ru)
PE (1) PE20030416A1 (ru)
PL (1) PL367716A1 (ru)
RS (1) RS17004A (ru)
UA (1) UA75957C2 (ru)
WO (1) WO2003018579A1 (ru)
ZA (1) ZA200400952B (ru)

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