NO328902B1 - Anvendelse av glykosaminoglykaner med en midlere molekylvekt lik 2400D for fremstilling av en farmasoytisk sammensetning for behandling av senil demens - Google Patents

Anvendelse av glykosaminoglykaner med en midlere molekylvekt lik 2400D for fremstilling av en farmasoytisk sammensetning for behandling av senil demens Download PDF

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Publication number
NO328902B1
NO328902B1 NO20015544A NO20015544A NO328902B1 NO 328902 B1 NO328902 B1 NO 328902B1 NO 20015544 A NO20015544 A NO 20015544A NO 20015544 A NO20015544 A NO 20015544A NO 328902 B1 NO328902 B1 NO 328902B1
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NO
Norway
Prior art keywords
molecular weight
treatment
glycosaminoglycans
senile dementia
use according
Prior art date
Application number
NO20015544A
Other languages
English (en)
Norwegian (no)
Other versions
NO20015544L (no
NO20015544D0 (no
Inventor
Luigi De Ambrosi
Israel Hanin
Jawed Fareed
John Lee
Stanley Lorens
Ronald F Mervis
Original Assignee
Cornelli Umberto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornelli Umberto filed Critical Cornelli Umberto
Publication of NO20015544D0 publication Critical patent/NO20015544D0/no
Publication of NO20015544L publication Critical patent/NO20015544L/no
Publication of NO328902B1 publication Critical patent/NO328902B1/no

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078Degradation products

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Polymers & Plastics (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
NO20015544A 1999-05-14 2001-11-13 Anvendelse av glykosaminoglykaner med en midlere molekylvekt lik 2400D for fremstilling av en farmasoytisk sammensetning for behandling av senil demens NO328902B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI001066A IT1312107B1 (it) 1999-05-14 1999-05-14 Glicosaminoglicani aventi peso molecolare medio di 2400 d atti altrattamento della demenza senile
PCT/EP2000/004311 WO2000069444A1 (en) 1999-05-14 2000-05-12 Glycosaminoglycans having an average molecular weight equal to 2400 d suitable for the treatment of senile dementia

Publications (3)

Publication Number Publication Date
NO20015544D0 NO20015544D0 (no) 2001-11-13
NO20015544L NO20015544L (no) 2002-01-14
NO328902B1 true NO328902B1 (no) 2010-06-14

Family

ID=11382970

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20015544A NO328902B1 (no) 1999-05-14 2001-11-13 Anvendelse av glykosaminoglykaner med en midlere molekylvekt lik 2400D for fremstilling av en farmasoytisk sammensetning for behandling av senil demens

Country Status (22)

Country Link
US (1) US6979680B1 (enExample)
EP (1) EP1181024B1 (enExample)
JP (1) JP2002544233A (enExample)
KR (1) KR100711142B1 (enExample)
CN (1) CN1178667C (enExample)
AT (1) ATE288761T1 (enExample)
AU (1) AU764743C (enExample)
CA (1) CA2373975A1 (enExample)
CZ (1) CZ20014092A3 (enExample)
DE (1) DE60018061T2 (enExample)
DK (1) DK1181024T3 (enExample)
ES (1) ES2237425T3 (enExample)
HK (1) HK1039903B (enExample)
HU (1) HUP0201100A3 (enExample)
IL (1) IL146458A0 (enExample)
IT (1) IT1312107B1 (enExample)
NO (1) NO328902B1 (enExample)
PL (1) PL198016B1 (enExample)
PT (1) PT1181024E (enExample)
RU (1) RU2248800C2 (enExample)
WO (1) WO2000069444A1 (enExample)
ZA (1) ZA200109331B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1344781A1 (en) * 2002-03-12 2003-09-17 Laboratori Derivati Organici S.P.A. Process for the depolymerization of glycosaminoglycanes and products obtained therefrom
ITMI20031023A1 (it) * 2003-05-21 2004-11-22 Umberto Cornelli Glicosaminoglicani aventi peso molecolare medio 2400 d atti al trattamento delle disfunzioni emozionali.
EP1524276A1 (en) * 2003-10-16 2005-04-20 Laboratori Derivati Organici S.P.A. Multistep process for the physical depolymerization of heparin and products obtained therefrom
US7939512B2 (en) 2004-10-13 2011-05-10 Laboratori Derivati Organici Spa Multistep process for the physical depolymerization of heparin and products obtained therefrom
AU2006342958A1 (en) 2005-12-22 2007-11-08 Bellus Health (International) Limited Treatment of renal disorders, diabetic nephropathy and dyslipidemias
WO2009007224A1 (en) * 2007-07-10 2009-01-15 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Low molecular weight heparin derivatives having neuroprotective activity
EP2283705B1 (en) 2008-05-22 2017-12-13 Vladimir Yegorovich Balakin Charged particle beam extraction apparatus used in conjunction with a charged particle cancer therapy system
WO2009142547A2 (en) 2008-05-22 2009-11-26 Vladimir Yegorovich Balakin Charged particle beam acceleration method and apparatus as part of a charged particle cancer therapy system
US8896239B2 (en) 2008-05-22 2014-11-25 Vladimir Yegorovich Balakin Charged particle beam injection method and apparatus used in conjunction with a charged particle cancer therapy system
US8901509B2 (en) 2008-05-22 2014-12-02 Vladimir Yegorovich Balakin Multi-axis charged particle cancer therapy method and apparatus
CA2725498C (en) 2008-05-22 2015-06-30 Vladimir Yegorovich Balakin Multi-field charged particle cancer therapy method and apparatus
JP2012519532A (ja) 2009-03-04 2012-08-30 ザクリトエ アクツィアニェールナエ オーブシチェストヴォ プロトム 多方向荷電粒子線癌治療方法及び装置
US8609097B2 (en) * 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
WO2013053954A1 (en) * 2011-10-14 2013-04-18 Centre National De La Recherche Scientifique Method of diagnosis, prognostic or treatment of neurodegenerative diseases
CN112426434A (zh) * 2020-11-04 2021-03-02 山东大学 硫酸乙酰肝素在防治阿尔兹海默症中的应用
CN114478816A (zh) * 2022-02-11 2022-05-13 上海兴糖生物技术有限公司 一种白玉蜗牛多糖及其制备方法和用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351938A (en) * 1980-05-19 1982-09-28 Riker Laboratories, Inc. Anticoagulant substance
US4847338A (en) * 1985-03-28 1989-07-11 University Of Iowa Research Foundation Low molecular weight heparin fragments as inhibitors of complement activation
EP0243974B1 (en) * 1986-05-01 1994-03-02 Toppan Printing Co., Ltd. Scanner set-up simulation apparatus
IT1213384B (it) * 1986-11-24 1989-12-20 Lab Derivati Organici Mediolan Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare.
IT1205042B (it) * 1987-05-28 1989-03-10 Crinos Industria Farmaco Composizione farmaceutica ad attivita' terapeutica per il trattamento della demenza senile di tipo alzheimer
EP0337327A1 (en) * 1988-04-09 1989-10-18 Bioiberica, S.A. Process for the preparation of new oligosaccharide fractions by controlled chemical depolimerization of heparin
IT1240615B (it) * 1990-04-03 1993-12-17 Mediolanum Farmaceutici Spa Impiego del dermatan solfato nella prevenzione e terapia dell'invecchiamento cerebrale e degli stati di deficit funzionale del sistema nervoso centrale
IL100555A (en) * 1991-02-07 2000-08-31 Hoechst Marion Roussel Inc N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them
SK279285B6 (sk) * 1991-05-02 1998-09-09 Daiichi Pharmaceutical Co. Použitie n-(2,6-dimetylfenyl)-2-(2-oxo-1-pyrolidin
RU2106864C1 (ru) * 1995-10-23 1998-03-20 Николай Серафимович Зефиров Средство для лечения болезни альцгеймера

Also Published As

Publication number Publication date
DE60018061D1 (de) 2005-03-17
PL352070A1 (en) 2003-07-28
IT1312107B1 (it) 2002-04-04
KR100711142B1 (ko) 2007-04-24
CA2373975A1 (en) 2000-11-23
JP2002544233A (ja) 2002-12-24
EP1181024B1 (en) 2005-02-09
AU764743C (en) 2004-03-18
AU4405200A (en) 2000-12-05
US6979680B1 (en) 2005-12-27
PT1181024E (pt) 2005-06-30
ATE288761T1 (de) 2005-02-15
EP1181024A1 (en) 2002-02-27
ITMI991066A1 (it) 2000-11-14
NO20015544L (no) 2002-01-14
CN1178667C (zh) 2004-12-08
KR20020005033A (ko) 2002-01-16
PL198016B1 (pl) 2008-05-30
HK1039903A1 (en) 2002-05-17
HUP0201100A2 (hu) 2002-07-29
HUP0201100A3 (en) 2003-03-28
CZ20014092A3 (cs) 2002-04-17
ES2237425T3 (es) 2005-08-01
NO20015544D0 (no) 2001-11-13
CN1350459A (zh) 2002-05-22
WO2000069444A1 (en) 2000-11-23
DE60018061T2 (de) 2006-04-13
DK1181024T3 (da) 2005-06-13
IL146458A0 (en) 2002-07-25
AU764743B2 (en) 2003-08-28
RU2248800C2 (ru) 2005-03-27
ZA200109331B (en) 2002-08-28
HK1039903B (en) 2005-08-26

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