AU764743C - Glycosaminoglycans having an average molecular weight of 2400 d suitable for the treatment of senile dementia - Google Patents
Glycosaminoglycans having an average molecular weight of 2400 d suitable for the treatment of senile dementiaInfo
- Publication number
- AU764743C AU764743C AU44052/00A AU4405200A AU764743C AU 764743 C AU764743 C AU 764743C AU 44052/00 A AU44052/00 A AU 44052/00A AU 4405200 A AU4405200 A AU 4405200A AU 764743 C AU764743 C AU 764743C
- Authority
- AU
- Australia
- Prior art keywords
- molecular weight
- glycosaminoglycan
- treatment
- average molecular
- senile dementia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 230000002792 vascular Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0078—Degradation products
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Polymers & Plastics (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI99A001066 | 1999-05-14 | ||
| IT1999MI001066A IT1312107B1 (it) | 1999-05-14 | 1999-05-14 | Glicosaminoglicani aventi peso molecolare medio di 2400 d atti altrattamento della demenza senile |
| PCT/EP2000/004311 WO2000069444A1 (en) | 1999-05-14 | 2000-05-12 | Glycosaminoglycans having an average molecular weight equal to 2400 d suitable for the treatment of senile dementia |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| AU4405200A AU4405200A (en) | 2000-12-05 |
| AU764743B2 AU764743B2 (en) | 2003-08-28 |
| AU764743C true AU764743C (en) | 2004-03-18 |
Family
ID=11382970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU44052/00A Ceased AU764743C (en) | 1999-05-14 | 2000-05-12 | Glycosaminoglycans having an average molecular weight of 2400 d suitable for the treatment of senile dementia |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6979680B1 (enExample) |
| EP (1) | EP1181024B1 (enExample) |
| JP (1) | JP2002544233A (enExample) |
| KR (1) | KR100711142B1 (enExample) |
| CN (1) | CN1178667C (enExample) |
| AT (1) | ATE288761T1 (enExample) |
| AU (1) | AU764743C (enExample) |
| CA (1) | CA2373975A1 (enExample) |
| CZ (1) | CZ20014092A3 (enExample) |
| DE (1) | DE60018061T2 (enExample) |
| DK (1) | DK1181024T3 (enExample) |
| ES (1) | ES2237425T3 (enExample) |
| HK (1) | HK1039903B (enExample) |
| HU (1) | HUP0201100A3 (enExample) |
| IL (1) | IL146458A0 (enExample) |
| IT (1) | IT1312107B1 (enExample) |
| NO (1) | NO328902B1 (enExample) |
| PL (1) | PL198016B1 (enExample) |
| PT (1) | PT1181024E (enExample) |
| RU (1) | RU2248800C2 (enExample) |
| WO (1) | WO2000069444A1 (enExample) |
| ZA (1) | ZA200109331B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1344781A1 (en) * | 2002-03-12 | 2003-09-17 | Laboratori Derivati Organici S.P.A. | Process for the depolymerization of glycosaminoglycanes and products obtained therefrom |
| ITMI20031023A1 (it) * | 2003-05-21 | 2004-11-22 | Umberto Cornelli | Glicosaminoglicani aventi peso molecolare medio 2400 d atti al trattamento delle disfunzioni emozionali. |
| EP1524276A1 (en) * | 2003-10-16 | 2005-04-20 | Laboratori Derivati Organici S.P.A. | Multistep process for the physical depolymerization of heparin and products obtained therefrom |
| US7939512B2 (en) | 2004-10-13 | 2011-05-10 | Laboratori Derivati Organici Spa | Multistep process for the physical depolymerization of heparin and products obtained therefrom |
| AU2006342958A1 (en) | 2005-12-22 | 2007-11-08 | Bellus Health (International) Limited | Treatment of renal disorders, diabetic nephropathy and dyslipidemias |
| WO2009007224A1 (en) * | 2007-07-10 | 2009-01-15 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Low molecular weight heparin derivatives having neuroprotective activity |
| EP2283705B1 (en) | 2008-05-22 | 2017-12-13 | Vladimir Yegorovich Balakin | Charged particle beam extraction apparatus used in conjunction with a charged particle cancer therapy system |
| WO2009142547A2 (en) | 2008-05-22 | 2009-11-26 | Vladimir Yegorovich Balakin | Charged particle beam acceleration method and apparatus as part of a charged particle cancer therapy system |
| US8896239B2 (en) | 2008-05-22 | 2014-11-25 | Vladimir Yegorovich Balakin | Charged particle beam injection method and apparatus used in conjunction with a charged particle cancer therapy system |
| US8901509B2 (en) | 2008-05-22 | 2014-12-02 | Vladimir Yegorovich Balakin | Multi-axis charged particle cancer therapy method and apparatus |
| CA2725498C (en) | 2008-05-22 | 2015-06-30 | Vladimir Yegorovich Balakin | Multi-field charged particle cancer therapy method and apparatus |
| JP2012519532A (ja) | 2009-03-04 | 2012-08-30 | ザクリトエ アクツィアニェールナエ オーブシチェストヴォ プロトム | 多方向荷電粒子線癌治療方法及び装置 |
| US8609097B2 (en) * | 2009-06-10 | 2013-12-17 | Hoffmann-La Roche Inc. | Use of an anti-Tau pS422 antibody for the treatment of brain diseases |
| WO2013053954A1 (en) * | 2011-10-14 | 2013-04-18 | Centre National De La Recherche Scientifique | Method of diagnosis, prognostic or treatment of neurodegenerative diseases |
| CN112426434A (zh) * | 2020-11-04 | 2021-03-02 | 山东大学 | 硫酸乙酰肝素在防治阿尔兹海默症中的应用 |
| CN114478816A (zh) * | 2022-02-11 | 2022-05-13 | 上海兴糖生物技术有限公司 | 一种白玉蜗牛多糖及其制备方法和用途 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0243974A2 (en) * | 1986-05-01 | 1987-11-04 | Toppan Printing Co., Ltd. | Scanner set-up simulation apparatus |
| EP0450508A2 (en) * | 1990-04-03 | 1991-10-09 | Mediolanum Farmaceutici S.P.A. | Use of dermatan sulphate for the prevention and therapy of cerebral aging and of central nervous system functional deficit states |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4351938A (en) * | 1980-05-19 | 1982-09-28 | Riker Laboratories, Inc. | Anticoagulant substance |
| US4847338A (en) * | 1985-03-28 | 1989-07-11 | University Of Iowa Research Foundation | Low molecular weight heparin fragments as inhibitors of complement activation |
| IT1213384B (it) * | 1986-11-24 | 1989-12-20 | Lab Derivati Organici Mediolan | Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare. |
| IT1205042B (it) * | 1987-05-28 | 1989-03-10 | Crinos Industria Farmaco | Composizione farmaceutica ad attivita' terapeutica per il trattamento della demenza senile di tipo alzheimer |
| EP0337327A1 (en) * | 1988-04-09 | 1989-10-18 | Bioiberica, S.A. | Process for the preparation of new oligosaccharide fractions by controlled chemical depolimerization of heparin |
| IL100555A (en) * | 1991-02-07 | 2000-08-31 | Hoechst Marion Roussel Inc | N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them |
| SK279285B6 (sk) * | 1991-05-02 | 1998-09-09 | Daiichi Pharmaceutical Co. | Použitie n-(2,6-dimetylfenyl)-2-(2-oxo-1-pyrolidin |
| RU2106864C1 (ru) * | 1995-10-23 | 1998-03-20 | Николай Серафимович Зефиров | Средство для лечения болезни альцгеймера |
-
1999
- 1999-05-14 IT IT1999MI001066A patent/IT1312107B1/it active
-
2000
- 2000-05-12 HU HU0201100A patent/HUP0201100A3/hu unknown
- 2000-05-12 DE DE60018061T patent/DE60018061T2/de not_active Expired - Fee Related
- 2000-05-12 IL IL14645800A patent/IL146458A0/xx not_active IP Right Cessation
- 2000-05-12 AU AU44052/00A patent/AU764743C/en not_active Ceased
- 2000-05-12 US US10/048,542 patent/US6979680B1/en not_active Expired - Fee Related
- 2000-05-12 HK HK02101550.8A patent/HK1039903B/en not_active IP Right Cessation
- 2000-05-12 WO PCT/EP2000/004311 patent/WO2000069444A1/en not_active Ceased
- 2000-05-12 KR KR1020017014505A patent/KR100711142B1/ko not_active Expired - Fee Related
- 2000-05-12 EP EP00925281A patent/EP1181024B1/en not_active Expired - Lifetime
- 2000-05-12 PT PT00925281T patent/PT1181024E/pt unknown
- 2000-05-12 JP JP2000617903A patent/JP2002544233A/ja active Pending
- 2000-05-12 AT AT00925281T patent/ATE288761T1/de not_active IP Right Cessation
- 2000-05-12 CA CA002373975A patent/CA2373975A1/en not_active Abandoned
- 2000-05-12 DK DK00925281T patent/DK1181024T3/da active
- 2000-05-12 CZ CZ20014092A patent/CZ20014092A3/cs unknown
- 2000-05-12 PL PL352070A patent/PL198016B1/pl not_active IP Right Cessation
- 2000-05-12 ES ES00925281T patent/ES2237425T3/es not_active Expired - Lifetime
- 2000-05-12 CN CNB00807562XA patent/CN1178667C/zh not_active Expired - Fee Related
- 2000-05-12 RU RU2001130882/14A patent/RU2248800C2/ru not_active IP Right Cessation
-
2001
- 2001-11-13 NO NO20015544A patent/NO328902B1/no not_active IP Right Cessation
- 2001-11-13 ZA ZA200109331A patent/ZA200109331B/xx unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0243974A2 (en) * | 1986-05-01 | 1987-11-04 | Toppan Printing Co., Ltd. | Scanner set-up simulation apparatus |
| EP0450508A2 (en) * | 1990-04-03 | 1991-10-09 | Mediolanum Farmaceutici S.P.A. | Use of dermatan sulphate for the prevention and therapy of cerebral aging and of central nervous system functional deficit states |
Also Published As
| Publication number | Publication date |
|---|---|
| DE60018061D1 (de) | 2005-03-17 |
| PL352070A1 (en) | 2003-07-28 |
| IT1312107B1 (it) | 2002-04-04 |
| KR100711142B1 (ko) | 2007-04-24 |
| CA2373975A1 (en) | 2000-11-23 |
| JP2002544233A (ja) | 2002-12-24 |
| EP1181024B1 (en) | 2005-02-09 |
| AU4405200A (en) | 2000-12-05 |
| US6979680B1 (en) | 2005-12-27 |
| NO328902B1 (no) | 2010-06-14 |
| PT1181024E (pt) | 2005-06-30 |
| ATE288761T1 (de) | 2005-02-15 |
| EP1181024A1 (en) | 2002-02-27 |
| ITMI991066A1 (it) | 2000-11-14 |
| NO20015544L (no) | 2002-01-14 |
| CN1178667C (zh) | 2004-12-08 |
| KR20020005033A (ko) | 2002-01-16 |
| PL198016B1 (pl) | 2008-05-30 |
| HK1039903A1 (en) | 2002-05-17 |
| HUP0201100A2 (hu) | 2002-07-29 |
| HUP0201100A3 (en) | 2003-03-28 |
| CZ20014092A3 (cs) | 2002-04-17 |
| ES2237425T3 (es) | 2005-08-01 |
| NO20015544D0 (no) | 2001-11-13 |
| CN1350459A (zh) | 2002-05-22 |
| WO2000069444A1 (en) | 2000-11-23 |
| DE60018061T2 (de) | 2006-04-13 |
| DK1181024T3 (da) | 2005-06-13 |
| IL146458A0 (en) | 2002-07-25 |
| AU764743B2 (en) | 2003-08-28 |
| RU2248800C2 (ru) | 2005-03-27 |
| ZA200109331B (en) | 2002-08-28 |
| HK1039903B (en) | 2005-08-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase | ||
| TH | Corrigenda |
Free format text: IN VOL 15, NO 10, PAGE(S) 1850-1853 UNDER THE HEADING APPLICATIONS LAPSED, REFUSED OR WITHDRAWN PLEASE DELETE ALL REFERENCE TO APPLICATION NO. 43862/00 AND 44052/00 |
|
| DA2 | Applications for amendment section 104 |
Free format text: THE NATURE OF THE PROPOSED AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 20030903 |
|
| DA3 | Amendments made section 104 |
Free format text: THE NATURE OF THE AMENDMENT IS AS WAS NOTIFIED IN THE OFFICIAL JOURNAL DATED 20031002 |
|
| FGA | Letters patent sealed or granted (standard patent) | ||
| DA3 | Amendments made section 104 |
Free format text: THE NATURE OF THE AMENDMENT IS: THE INVENTION TITLE SHOULD READ: GLYCOSAMINOGLYCANS HAVING AN AVERAGE MOLECULAR WEIGHT OF 2400 D SUITABLE FOR THE TREATMENT OF SENILE DEMENTIA |