ATE288761T1 - Verwendung von glykosaminoglykane zur behandlung seniler demenz - Google Patents

Verwendung von glykosaminoglykane zur behandlung seniler demenz

Info

Publication number
ATE288761T1
ATE288761T1 AT00925281T AT00925281T ATE288761T1 AT E288761 T1 ATE288761 T1 AT E288761T1 AT 00925281 T AT00925281 T AT 00925281T AT 00925281 T AT00925281 T AT 00925281T AT E288761 T1 ATE288761 T1 AT E288761T1
Authority
AT
Austria
Prior art keywords
senile dementia
glycosaminoglycans
treat senile
treatment
alzheimer
Prior art date
Application number
AT00925281T
Other languages
English (en)
Inventor
Umberto Cornelli
Ambrosi Luigi De
Israel Hanin
Jawed Fareed
John Lee
Stanley Lorens
Ronald F Mervis
Original Assignee
Umberto Cornelli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Umberto Cornelli filed Critical Umberto Cornelli
Application granted granted Critical
Publication of ATE288761T1 publication Critical patent/ATE288761T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Materials Engineering (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
AT00925281T 1999-05-14 2000-05-12 Verwendung von glykosaminoglykane zur behandlung seniler demenz ATE288761T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI001066A IT1312107B1 (it) 1999-05-14 1999-05-14 Glicosaminoglicani aventi peso molecolare medio di 2400 d atti altrattamento della demenza senile
PCT/EP2000/004311 WO2000069444A1 (en) 1999-05-14 2000-05-12 Glycosaminoglycans having an average molecular weight equal to 2400 d suitable for the treatment of senile dementia

Publications (1)

Publication Number Publication Date
ATE288761T1 true ATE288761T1 (de) 2005-02-15

Family

ID=11382970

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00925281T ATE288761T1 (de) 1999-05-14 2000-05-12 Verwendung von glykosaminoglykane zur behandlung seniler demenz

Country Status (22)

Country Link
US (1) US6979680B1 (de)
EP (1) EP1181024B1 (de)
JP (1) JP2002544233A (de)
KR (1) KR100711142B1 (de)
CN (1) CN1178667C (de)
AT (1) ATE288761T1 (de)
AU (1) AU764743C (de)
CA (1) CA2373975A1 (de)
CZ (1) CZ20014092A3 (de)
DE (1) DE60018061T2 (de)
DK (1) DK1181024T3 (de)
ES (1) ES2237425T3 (de)
HK (1) HK1039903B (de)
HU (1) HUP0201100A3 (de)
IL (1) IL146458A0 (de)
IT (1) IT1312107B1 (de)
NO (1) NO328902B1 (de)
PL (1) PL198016B1 (de)
PT (1) PT1181024E (de)
RU (1) RU2248800C2 (de)
WO (1) WO2000069444A1 (de)
ZA (1) ZA200109331B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1344781A1 (de) * 2002-03-12 2003-09-17 Laboratori Derivati Organici S.P.A. Verfahren zur Depolymerisierung von Glykosaminoglykanen und so hergestellte Produkte
ITMI20031023A1 (it) * 2003-05-21 2004-11-22 Umberto Cornelli Glicosaminoglicani aventi peso molecolare medio 2400 d atti al trattamento delle disfunzioni emozionali.
EP1524276A1 (de) * 2003-10-16 2005-04-20 Laboratori Derivati Organici S.P.A. Mehrstufenverfahren für die physikalisische Depolymerisation von Heparin und die so erhaltenen Produkte
US7939512B2 (en) 2004-10-13 2011-05-10 Laboratori Derivati Organici Spa Multistep process for the physical depolymerization of heparin and products obtained therefrom
ES2352801T3 (es) 2005-12-22 2011-02-23 Kiacta Sàrl Tratamiento de nefropatía diabética.
WO2009007224A1 (en) * 2007-07-10 2009-01-15 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Low molecular weight heparin derivatives having neuroprotective activity
WO2009142550A2 (en) 2008-05-22 2009-11-26 Vladimir Yegorovich Balakin Charged particle beam extraction method and apparatus used in conjunction with a charged particle cancer therapy system
WO2009142549A2 (en) 2008-05-22 2009-11-26 Vladimir Yegorovich Balakin Multi-axis charged particle cancer therapy method and apparatus
US8896239B2 (en) 2008-05-22 2014-11-25 Vladimir Yegorovich Balakin Charged particle beam injection method and apparatus used in conjunction with a charged particle cancer therapy system
AU2009249863B2 (en) 2008-05-22 2013-12-12 Vladimir Yegorovich Balakin Multi-field charged particle cancer therapy method and apparatus
EP2283711B1 (de) 2008-05-22 2018-07-11 Vladimir Yegorovich Balakin Beschleunigungsvorrichtung für strahlen geladener teilchen als teil eines krebstherapiesystems mit geladenen teilchen
EP2403599A4 (de) 2009-03-04 2017-11-22 Zakrytoe Aktsionernoe Obshchestvo Protom Verfahren und vorrichtung für die krebstherapie mit geladenen teilchen mit mehreren feldern
US8609097B2 (en) * 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
AU2012322762B2 (en) * 2011-10-14 2018-03-08 Assistance Publique-Hospitaux De PAris Method of diagnosis, prognostic or treatment of neurodegenerative diseases
CN112426434A (zh) * 2020-11-04 2021-03-02 山东大学 硫酸乙酰肝素在防治阿尔兹海默症中的应用
CN114478816A (zh) * 2022-02-11 2022-05-13 上海兴糖生物技术有限公司 一种白玉蜗牛多糖及其制备方法和用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351938A (en) * 1980-05-19 1982-09-28 Riker Laboratories, Inc. Anticoagulant substance
US4847338A (en) * 1985-03-28 1989-07-11 University Of Iowa Research Foundation Low molecular weight heparin fragments as inhibitors of complement activation
DE3789159T2 (de) * 1986-05-01 1994-07-28 Toppan Printing Co Ltd Vorrichtung zur Simulation der Einstellung eines Abtasters.
IT1213384B (it) * 1986-11-24 1989-12-20 Lab Derivati Organici Mediolan Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare.
IT1205042B (it) 1987-05-28 1989-03-10 Crinos Industria Farmaco Composizione farmaceutica ad attivita' terapeutica per il trattamento della demenza senile di tipo alzheimer
EP0337327A1 (de) * 1988-04-09 1989-10-18 Bioiberica, S.A. Verfahren zur Herstellung von neuen Oligosaccharid-Fragmenten durch kontrollierte chemische Depolymerisation von Heparin
IT1240615B (it) 1990-04-03 1993-12-17 Mediolanum Farmaceutici Spa Impiego del dermatan solfato nella prevenzione e terapia dell'invecchiamento cerebrale e degli stati di deficit funzionale del sistema nervoso centrale
IL100555A (en) * 1991-02-07 2000-08-31 Hoechst Marion Roussel Inc N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them
SK279285B6 (sk) * 1991-05-02 1998-09-09 Daiichi Pharmaceutical Co. Použitie n-(2,6-dimetylfenyl)-2-(2-oxo-1-pyrolidin
RU2106864C1 (ru) * 1995-10-23 1998-03-20 Николай Серафимович Зефиров Средство для лечения болезни альцгеймера

Also Published As

Publication number Publication date
DE60018061T2 (de) 2006-04-13
HUP0201100A3 (en) 2003-03-28
NO20015544L (no) 2002-01-14
EP1181024B1 (de) 2005-02-09
CZ20014092A3 (cs) 2002-04-17
KR20020005033A (ko) 2002-01-16
JP2002544233A (ja) 2002-12-24
AU764743B2 (en) 2003-08-28
HUP0201100A2 (hu) 2002-07-29
CN1178667C (zh) 2004-12-08
WO2000069444A1 (en) 2000-11-23
CN1350459A (zh) 2002-05-22
EP1181024A1 (de) 2002-02-27
US6979680B1 (en) 2005-12-27
IT1312107B1 (it) 2002-04-04
CA2373975A1 (en) 2000-11-23
DE60018061D1 (de) 2005-03-17
AU4405200A (en) 2000-12-05
PL198016B1 (pl) 2008-05-30
AU764743C (en) 2004-03-18
ZA200109331B (en) 2002-08-28
RU2248800C2 (ru) 2005-03-27
DK1181024T3 (da) 2005-06-13
HK1039903A1 (en) 2002-05-17
PL352070A1 (en) 2003-07-28
ES2237425T3 (es) 2005-08-01
PT1181024E (pt) 2005-06-30
IL146458A0 (en) 2002-07-25
KR100711142B1 (ko) 2007-04-24
ITMI991066A1 (it) 2000-11-14
NO328902B1 (no) 2010-06-14
NO20015544D0 (no) 2001-11-13
HK1039903B (en) 2005-08-26

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