NO325879B1 - Rekombinant DNA-konstruksjon nyttig for uttrykking av protein og en vektor. - Google Patents

Rekombinant DNA-konstruksjon nyttig for uttrykking av protein og en vektor. Download PDF

Info

Publication number
NO325879B1
NO325879B1 NO19975286A NO975286A NO325879B1 NO 325879 B1 NO325879 B1 NO 325879B1 NO 19975286 A NO19975286 A NO 19975286A NO 975286 A NO975286 A NO 975286A NO 325879 B1 NO325879 B1 NO 325879B1
Authority
NO
Norway
Prior art keywords
protein
recombinant dna
promoter
expression
region
Prior art date
Application number
NO19975286A
Other languages
English (en)
Norwegian (no)
Other versions
NO975286L (no
NO975286D0 (no
Inventor
Peter A Lagosky
Original Assignee
Allelix Biopharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allelix Biopharma filed Critical Allelix Biopharma
Publication of NO975286L publication Critical patent/NO975286L/no
Publication of NO975286D0 publication Critical patent/NO975286D0/no
Publication of NO325879B1 publication Critical patent/NO325879B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/72Expression systems using regulatory sequences derived from the lac-operon
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/635Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO19975286A 1995-05-19 1997-11-18 Rekombinant DNA-konstruksjon nyttig for uttrykking av protein og en vektor. NO325879B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/445,133 US5629205A (en) 1995-05-19 1995-05-19 Promoters for gene expression
PCT/IB1996/000462 WO1996036721A1 (en) 1995-05-19 1996-05-16 Promoters for gene expression

Publications (3)

Publication Number Publication Date
NO975286L NO975286L (no) 1997-11-18
NO975286D0 NO975286D0 (no) 1997-11-18
NO325879B1 true NO325879B1 (no) 2008-08-11

Family

ID=23767732

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19975286A NO325879B1 (no) 1995-05-19 1997-11-18 Rekombinant DNA-konstruksjon nyttig for uttrykking av protein og en vektor.

Country Status (25)

Country Link
US (1) US5629205A (de)
EP (1) EP0828844B1 (de)
JP (2) JP3828576B2 (de)
KR (1) KR19990014906A (de)
CN (1) CN1131313C (de)
AT (1) ATE248923T1 (de)
AU (1) AU698656B2 (de)
BR (1) BR9609102A (de)
CA (1) CA2221587C (de)
CZ (1) CZ357997A3 (de)
DE (1) DE69629808T2 (de)
DK (1) DK0828844T3 (de)
EE (1) EE9700355A (de)
ES (1) ES2202436T3 (de)
HK (1) HK1004148A1 (de)
HU (1) HUP9900750A3 (de)
IS (1) IS4609A (de)
MX (1) MX9708689A (de)
NO (1) NO325879B1 (de)
NZ (1) NZ306536A (de)
PL (1) PL324226A1 (de)
PT (1) PT828844E (de)
SK (1) SK154997A3 (de)
TR (1) TR199701394T1 (de)
WO (1) WO1996036721A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194168B1 (en) 1997-09-30 2001-02-27 Human Genome Sciences, Inc. Expression control sequences
WO2003099854A2 (en) * 2002-05-24 2003-12-04 Nps Allelix Corp. Method for enzymatic production of glp-2(1-33) and glp-2-(1-34) peptides
US20050119183A1 (en) * 2003-11-12 2005-06-02 Nps Allelix Corp. Method for treating bone loss using parathyroid hormone
SI1704234T1 (sl) 2003-11-21 2012-08-31 Nps Pharma Inc Proizvodnja glukagonu podobnih peptidov 2 in analogov
WO2005058946A2 (en) * 2003-12-12 2005-06-30 Zymogenetics, Inc. Methods for enhancing expression of recombinant proteins
SG11201404991YA (en) 2012-02-23 2014-09-26 Stage Cell Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
WO2018197949A1 (en) 2017-04-27 2018-11-01 Juno Therapeutics Gmbh Oligomeric particle reagents and methods of use thereof
CN108060168B (zh) * 2017-12-29 2021-06-29 苏州金唯智生物科技有限公司 一种改进的启动子及其组成的t载体和应用
CN108118059B (zh) * 2017-12-30 2021-03-19 苏州金唯智生物科技有限公司 一种改进的启动子及其组成的载体和应用
CN108165551B (zh) * 2017-12-30 2021-06-29 苏州金唯智生物科技有限公司 一种改进的启动子及其组成的t载体和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8517071D0 (en) * 1985-07-05 1985-08-14 Hoffmann La Roche Gram-positive expression control sequence
ATE123526T1 (de) * 1987-08-17 1995-06-15 Hoffmann La Roche Hochreprimierbare expressionskontrollsequenzen.
US5223407A (en) * 1988-08-31 1993-06-29 Allelix Inc. Excretion of heterologous proteins from e. coli
US5171670A (en) * 1989-05-12 1992-12-15 The General Hospital Corporation Recombinant dna method for production of parathyroid hormone
JPH05509001A (ja) * 1990-08-28 1993-12-16 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 有効な分泌用ベクター類の迅速選択方法

Also Published As

Publication number Publication date
EP0828844A1 (de) 1998-03-18
HUP9900750A3 (en) 1999-11-29
JP3837154B2 (ja) 2006-10-25
CN1131313C (zh) 2003-12-17
SK154997A3 (en) 1998-05-06
US5629205A (en) 1997-05-13
TR199701394T1 (xx) 1998-02-21
NO975286L (no) 1997-11-18
BR9609102A (pt) 1999-05-11
EE9700355A (et) 1998-06-15
JP2006187295A (ja) 2006-07-20
JP3828576B2 (ja) 2006-10-04
PT828844E (pt) 2004-01-30
HK1004148A1 (en) 1998-11-20
IS4609A (is) 1997-11-07
NO975286D0 (no) 1997-11-18
DE69629808D1 (de) 2003-10-09
CA2221587C (en) 2008-07-08
WO1996036721A1 (en) 1996-11-21
JPH11509083A (ja) 1999-08-17
AU698656B2 (en) 1998-11-05
EP0828844B1 (de) 2003-09-03
DK0828844T3 (da) 2004-01-05
DE69629808T2 (de) 2004-07-15
HUP9900750A2 (hu) 1999-06-28
AU5511696A (en) 1996-11-29
ATE248923T1 (de) 2003-09-15
CN1190993A (zh) 1998-08-19
CZ357997A3 (cs) 1998-04-15
CA2221587A1 (en) 1996-11-21
KR19990014906A (ko) 1999-02-25
NZ306536A (en) 1999-10-28
PL324226A1 (en) 1998-05-11
ES2202436T3 (es) 2004-04-01
MX9708689A (es) 1998-02-28

Similar Documents

Publication Publication Date Title
JP3837154B2 (ja) 遺伝子発現用プロモーター
Rosenberg et al. Effects of consecutive AGG codons on translation in Escherichia coli, demonstrated with a versatile codon test system
Kawasaki et al. Roles of Escherichia coli heat shock proteins DnaK, DnaJ and GrpE in mini-F plasmid replication
NO324920B1 (no) Fremgangsmate for a sekretere et aktuelt heterologt polypeptid i en celle, nukleinsyre som koder for en sekresjonssignalsekvensvariant av STII og en variant av STII-sekresjonssignalsekvensen.
SK116896A3 (en) Enhanced secretion of polypeptides
Baty et al. Extracellular release of colicin A is non‐specific.
CA2346122A1 (en) Stabilized bioactive peptides and methods of identification, synthesis and use
WO1999016858A1 (en) Expression control sequences
US6395965B1 (en) Plant containing a gene construct comprising a chlorella virus promoter and a lac operator
KR20170017415A (ko) 큐메이트 오페론에 의해 조절되는 유전자 발현용 카세트
MXPA97008689A (en) Promoters of the expression of ge
CA2414978C (en) Preparation of a recombinant protein in a prokaryotic host cell
JP2000189163A (ja) トリガ―ファクタ―発現プラスミド
Yamamoto et al. Molecular organization of heat-labile enterotoxin genes originating in Escherichia coli of human origin and construction of heat-labile toxoid-producing strains
WO2000060103A2 (en) Dna construct comprising a cyanophage of cyanobacteria promoter and its use
SG178293A1 (en) Fermentation process
KR20090018315A (ko) 대장균 유래 ptsL 프로모터를 함유하는 재조합벡터 및이를 이용한 외래 단백질의 제조방법
Giza et al. A self-inducing runaway-replication plasmid expression system utilizing the Rop protein
EP0141362A2 (de) Plasmid-Vektor
Lebedeva et al. A new T7 RNA polymerase-driven expression system induced via thermoamplification of a recombinant plasmid carrying a T7 promoter-Escherichia coli lac operator
Roytrakul et al. A Rapid and Simple Method for Construction and Expression of a Synthetic
Giladi et al. Selective stabilization by the bacteriophage 434 repressor of the plasmid expressing bovine growth hormone in Escherichia coli
JPH0759580A (ja) ヒトカルシトニン前駆体ペプチドの製造法
Markers The pET System: Your Choice for Expression
IE912853A1 (en) IMPROVED BACTERIOPHAGE LAMBDA pL PROMOTERS

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application
MK1K Patent expired