NO323994B1 - Fremgangsmate for affinitetsseparasjon, samt albuminbindingsprotein, fusjonsprotein, nukleinsyremolekyl og vertscelle. - Google Patents
Fremgangsmate for affinitetsseparasjon, samt albuminbindingsprotein, fusjonsprotein, nukleinsyremolekyl og vertscelle. Download PDFInfo
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- NO323994B1 NO323994B1 NO20011969A NO20011969A NO323994B1 NO 323994 B1 NO323994 B1 NO 323994B1 NO 20011969 A NO20011969 A NO 20011969A NO 20011969 A NO20011969 A NO 20011969A NO 323994 B1 NO323994 B1 NO 323994B1
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- 108091005573 modified proteins Proteins 0.000 description 1
- 238000010369 molecular cloning Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
- 238000010899 nucleation Methods 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 125000006239 protecting group Chemical group 0.000 description 1
- 238000000159 protein binding assay Methods 0.000 description 1
- 235000004252 protein component Nutrition 0.000 description 1
- 108020001580 protein domains Proteins 0.000 description 1
- 230000017854 proteolysis Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 238000002741 site-directed mutagenesis Methods 0.000 description 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 150000003573 thiols Chemical class 0.000 description 1
- 125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9823071.7A GB9823071D0 (en) | 1998-10-21 | 1998-10-21 | A method |
| PCT/GB1999/003484 WO2000023580A1 (en) | 1998-10-21 | 1999-10-21 | A method of affinity separation and ligands for use therein |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20011969D0 NO20011969D0 (no) | 2001-04-20 |
| NO20011969L NO20011969L (no) | 2001-06-19 |
| NO323994B1 true NO323994B1 (no) | 2007-07-30 |
Family
ID=10841043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20011969A NO323994B1 (no) | 1998-10-21 | 2001-04-20 | Fremgangsmate for affinitetsseparasjon, samt albuminbindingsprotein, fusjonsprotein, nukleinsyremolekyl og vertscelle. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6831161B1 (https=) |
| EP (2) | EP1672068A1 (https=) |
| JP (1) | JP4801258B2 (https=) |
| AT (1) | ATE305970T1 (https=) |
| AU (1) | AU773368B2 (https=) |
| CA (2) | CA2633345C (https=) |
| DE (1) | DE69927598T2 (https=) |
| DK (1) | DK1123389T3 (https=) |
| GB (1) | GB9823071D0 (https=) |
| NO (1) | NO323994B1 (https=) |
| WO (1) | WO2000023580A1 (https=) |
| ZA (1) | ZA200103252B (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0200943D0 (sv) * | 2002-03-25 | 2002-03-25 | Amersham Biosciences Ab | Mutant protein |
| US7709209B2 (en) | 2002-03-25 | 2010-05-04 | Ge Healthcare Bio-Sciences Ab | Protein ligands |
| GB0214007D0 (en) * | 2002-06-18 | 2002-07-31 | Common Services Agency | Removal of prion infectivity |
| AU2004245429A1 (en) * | 2003-06-10 | 2004-12-16 | Farallone Holding Bv | Binding peptides: methods for their generation and use |
| SE0301936D0 (sv) * | 2003-06-30 | 2003-06-30 | Affibody Ab | New polypeptide |
| US7993650B2 (en) | 2003-07-04 | 2011-08-09 | Affibody Ab | Polypeptides having binding affinity for HER2 |
| JP5634008B2 (ja) | 2004-04-06 | 2014-12-03 | アフィボディ・アーベー | 新規の使用および方法 |
| EP2066419B1 (en) | 2006-09-29 | 2015-11-11 | GE Healthcare Bio-Sciences AB | Chromatography ligand comprising domain c from staphyloccocus aureus protein a for antibody isolation |
| CA2694139C (en) * | 2007-07-31 | 2018-06-05 | Affibody Ab | Albumin binding polypeptide compositions |
| GB2452301A (en) | 2007-08-30 | 2009-03-04 | Ge Healthcare Bio Sciences Ab | Sterilization Method |
| US8592555B2 (en) * | 2008-08-11 | 2013-11-26 | Emd Millipore Corporation | Immunoglobulin-binding proteins with improved specificity |
| CN102165312B (zh) * | 2008-09-25 | 2015-04-22 | Jsr株式会社 | 亲合层析用填充剂 |
| JP5229888B2 (ja) * | 2008-09-30 | 2013-07-03 | 独立行政法人産業技術総合研究所 | 弱酸性域での易解離性を向上したプロテインａ変異型タンパク質及び抗体捕捉剤 |
| SG195555A1 (en) * | 2008-12-24 | 2013-12-30 | Emd Millipore Corp | Caustic stable chromatography ligands |
| WO2010110288A1 (ja) | 2009-03-24 | 2010-09-30 | 株式会社カネカ | 免疫グロブリンに親和性を有するタンパク質および免疫グロブリン結合性アフィニティーリガンド |
| SG184184A1 (en) | 2010-03-24 | 2012-10-30 | Kaneka Corp | Protein capable of binding specifically to immunoglobulin, and immunoglobulin-binding affinity ligand |
| WO2012086660A1 (ja) | 2010-12-21 | 2012-06-28 | Jsr株式会社 | アフィニティークロマトグラフィー用担体およびイムノグロブリンを単離する方法 |
| CN103403020A (zh) * | 2010-12-21 | 2013-11-20 | Jsr株式会社 | 蛋白a的新型耐碱变体及其在亲和色谱中的用途 |
| JP6038774B2 (ja) * | 2011-03-24 | 2016-12-07 | 株式会社カネカ | タンパク性物質結合性低分子化合物 |
| WO2012133342A1 (ja) | 2011-03-25 | 2012-10-04 | 株式会社カネカ | 免疫グロブリン結合性新規ポリペプチド |
| SG186552A1 (en) | 2011-06-08 | 2013-01-30 | Emd Millipore Corp | Chromatography matrices including novel staphylococcus aureus protein a based ligands |
| WO2014076177A1 (en) * | 2012-11-14 | 2014-05-22 | Affibody Ab | New polypeptide |
| WO2014076179A1 (en) | 2012-11-14 | 2014-05-22 | Affibody Ab | New polypeptide |
| USRE48805E1 (en) | 2013-03-06 | 2021-11-02 | Vision Global Holdings Ltd. | Method for cancer targeting treatment and detection of arginine using albumin-binding arginine deiminase fusion protein |
| US9255262B2 (en) * | 2013-03-06 | 2016-02-09 | Vision Global Holdings Ltd. | Albumin-binding arginine deminase and the use thereof |
| JP6306189B2 (ja) | 2013-09-04 | 2018-04-04 | イー・エム・デイー・ミリポア・コーポレイシヨン | プロテインａ系親和性クロマトグラフィーカラムを洗浄する方法 |
| EP3050902B1 (en) | 2013-09-27 | 2018-11-21 | Kaneka Corporation | Process for producing porous cellulose beads using alkali aqueous solution, and porous cellulose beads produced by this process |
| WO2015088677A1 (en) | 2013-12-12 | 2015-06-18 | Emd Millipore Corporation | Protein separations using an acrylamide containing filter |
| JP6369807B2 (ja) * | 2014-10-21 | 2018-08-08 | 株式会社プロテイン・エクスプレス | プロテインｌ変異体 |
| JP6663360B2 (ja) | 2015-01-26 | 2020-03-11 | 株式会社カネカ | 変異型免疫グロブリンκ鎖可変領域結合性ペプチド |
| WO2016121701A1 (ja) | 2015-01-26 | 2016-08-04 | 株式会社カネカ | 免疫グロブリンκ鎖可変領域含有タンパク質精製用アフィニティー分離マトリックス |
| EP3276002B1 (en) | 2015-03-26 | 2020-04-29 | JSR Corporation | Immunoglobulin-binding protein and affinity carrier using same |
| EP3283508B1 (en) | 2015-04-17 | 2021-03-17 | Alpine Immune Sciences, Inc. | Immunomodulatory proteins with tunable affinities |
| US11208441B2 (en) | 2015-10-22 | 2021-12-28 | Protenova Co., Ltd. | Immunoglobulin-binding polypeptide |
| WO2017191748A1 (ja) * | 2016-05-02 | 2017-11-09 | 株式会社カネカ | 改変型免疫グロブリンκ鎖可変領域結合性ペプチド |
| WO2017195638A1 (ja) | 2016-05-09 | 2017-11-16 | 株式会社カネカ | 抗体またはκ鎖可変領域含有抗体断片の精製方法 |
| US11660550B2 (en) | 2017-03-07 | 2023-05-30 | Jmva Biotech Ab | Modified adsorptive surfaces |
| TWI888342B (zh) | 2017-09-25 | 2025-07-01 | 日商Ｊｓｒ股份有限公司 | 免疫球蛋白結合蛋白質，及使用其之親和性載體 |
| BR112020020604A2 (pt) | 2018-04-11 | 2021-01-12 | Inhibrx, Inc. | Construções de polipeptídeo multiespecífico tendo ligação restrita de cd3 e métodos e usos relacionados |
| EP3842536A4 (en) | 2018-08-24 | 2023-01-18 | JSR Corporation | IMMUNOGLOBULIN-BINDING PROTEIN AND AFFINITY CARRIER WITH IT |
| US20240026344A1 (en) | 2020-10-13 | 2024-01-25 | Avitide LLC | Affinity ligand libraries of three-helix bundle proteins and uses thereof |
| WO2022138718A1 (ja) | 2020-12-22 | 2022-06-30 | プロテノバ株式会社 | イムノグロブリン結合ポリペプチド |
| CN117241866A (zh) | 2021-02-19 | 2023-12-15 | 艾维泰有限责任公司 | Aav2亲和剂 |
| GB2609185A (en) | 2021-05-24 | 2023-02-01 | Astrea Uk Services Ltd | Scaffold for isolation of a biomolecule |
| EP4541814A1 (en) * | 2023-10-20 | 2025-04-23 | Cytiva BioProcess R&D AB | Stabilized polypeptides |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE462046C (sv) * | 1982-08-23 | 1998-04-27 | Pharmacia Biotech Ab | Hybrid-DNA-vektor innehållande DNA-sekvens från Staphylococcus aureus, förfarande för dess framställning och bakterie innehållande densamma |
| US5401832A (en) * | 1984-12-24 | 1995-03-28 | Merck & Co., Inc. | Brain derived and recombinant acidic fibroblast growth factor |
| US5089473A (en) * | 1988-08-29 | 1992-02-18 | Monsanto Company | Somatotropin variants and their use |
| WO1993002107A1 (fr) * | 1991-07-25 | 1993-02-04 | Oriental Yeast Co., Ltd. | Proteine artificielle de combinaison avec les immunoglobulines |
| JP2584697B2 (ja) * | 1991-08-23 | 1997-02-26 | オリエンタル酵母工業株式会社 | ＩｇＧ精製用組換え型プロテインＡ |
| DE59306762D1 (de) * | 1992-04-16 | 1997-07-24 | Merck Patent Gmbh | Aktivierte Trägermaterialien, ihre Herstellung und Verwendung |
| SE9400088D0 (sv) * | 1994-01-14 | 1994-01-14 | Kabi Pharmacia Ab | Bacterial receptor structures |
| US5736499A (en) * | 1995-06-06 | 1998-04-07 | Genencor International, Inc. | Mutant A-amylase |
| SE9503925D0 (sv) * | 1995-11-07 | 1995-11-07 | Pharmacia Biotech Ab | Separationsmedium för IgG |
| JP2002508656A (ja) * | 1997-03-12 | 2002-03-19 | スミスクライン・ビーチャム・コーポレイション | 抗−アルファベータ３ヒト化モノクローナル抗体 |
-
1998
- 1998-10-21 GB GBGB9823071.7A patent/GB9823071D0/en not_active Ceased
-
1999
- 1999-10-21 AT AT99950942T patent/ATE305970T1/de not_active IP Right Cessation
- 1999-10-21 DK DK99950942T patent/DK1123389T3/da active
- 1999-10-21 EP EP05077192A patent/EP1672068A1/en not_active Ceased
- 1999-10-21 CA CA2633345A patent/CA2633345C/en not_active Expired - Lifetime
- 1999-10-21 JP JP2000577291A patent/JP4801258B2/ja not_active Expired - Lifetime
- 1999-10-21 DE DE69927598T patent/DE69927598T2/de not_active Expired - Lifetime
- 1999-10-21 AU AU63532/99A patent/AU773368B2/en not_active Expired
- 1999-10-21 WO PCT/GB1999/003484 patent/WO2000023580A1/en not_active Ceased
- 1999-10-21 EP EP99950942A patent/EP1123389B1/en not_active Expired - Lifetime
- 1999-10-21 US US09/830,080 patent/US6831161B1/en not_active Expired - Lifetime
- 1999-10-21 CA CA002347960A patent/CA2347960C/en not_active Expired - Lifetime
-
2001
- 2001-04-20 ZA ZA200103252A patent/ZA200103252B/en unknown
- 2001-04-20 NO NO20011969A patent/NO323994B1/no not_active IP Right Cessation
-
2004
- 2004-12-01 US US11/000,747 patent/US20050100970A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1123389A1 (en) | 2001-08-16 |
| CA2633345A1 (en) | 2000-04-27 |
| DE69927598T2 (de) | 2006-07-13 |
| JP2002527107A (ja) | 2002-08-27 |
| CA2347960C (en) | 2008-08-05 |
| JP4801258B2 (ja) | 2011-10-26 |
| CA2347960A1 (en) | 2000-04-27 |
| ZA200103252B (en) | 2002-07-22 |
| DE69927598D1 (de) | 2006-02-16 |
| NO20011969L (no) | 2001-06-19 |
| US20050100970A1 (en) | 2005-05-12 |
| ATE305970T1 (de) | 2005-10-15 |
| GB9823071D0 (en) | 1998-12-16 |
| AU6353299A (en) | 2000-05-08 |
| DK1123389T3 (da) | 2006-01-16 |
| CA2633345C (en) | 2013-02-26 |
| EP1672068A1 (en) | 2006-06-21 |
| AU773368B2 (en) | 2004-05-20 |
| WO2000023580A1 (en) | 2000-04-27 |
| EP1123389B1 (en) | 2005-10-05 |
| NO20011969D0 (no) | 2001-04-20 |
| US6831161B1 (en) | 2004-12-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |