JP4801258B2 - アフィニティ分離の方法及びそれに用いるリガンド - Google Patents

アフィニティ分離の方法及びそれに用いるリガンド Download PDF

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JP4801258B2
JP4801258B2 JP2000577291A JP2000577291A JP4801258B2 JP 4801258 B2 JP4801258 B2 JP 4801258B2 JP 2000577291 A JP2000577291 A JP 2000577291A JP 2000577291 A JP2000577291 A JP 2000577291A JP 4801258 B2 JP4801258 B2 JP 4801258B2
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protein
asn
affinity
binding
residues
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JP2002527107A (ja
JP2002527107A5 (https=
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ユーレン、マーチアス
ホバー、ソフィア
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2000577291A 1998-10-21 1999-10-21 アフィニティ分離の方法及びそれに用いるリガンド Expired - Lifetime JP4801258B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9823071.7A GB9823071D0 (en) 1998-10-21 1998-10-21 A method
GB9823071.7 1998-10-21
PCT/GB1999/003484 WO2000023580A1 (en) 1998-10-21 1999-10-21 A method of affinity separation and ligands for use therein

Publications (3)

Publication Number Publication Date
JP2002527107A JP2002527107A (ja) 2002-08-27
JP2002527107A5 JP2002527107A5 (https=) 2006-12-07
JP4801258B2 true JP4801258B2 (ja) 2011-10-26

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JP2000577291A Expired - Lifetime JP4801258B2 (ja) 1998-10-21 1999-10-21 アフィニティ分離の方法及びそれに用いるリガンド

Country Status (12)

Country Link
US (2) US6831161B1 (https=)
EP (2) EP1672068A1 (https=)
JP (1) JP4801258B2 (https=)
AT (1) ATE305970T1 (https=)
AU (1) AU773368B2 (https=)
CA (2) CA2633345C (https=)
DE (1) DE69927598T2 (https=)
DK (1) DK1123389T3 (https=)
GB (1) GB9823071D0 (https=)
NO (1) NO323994B1 (https=)
WO (1) WO2000023580A1 (https=)
ZA (1) ZA200103252B (https=)

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AU2004245429A1 (en) * 2003-06-10 2004-12-16 Farallone Holding Bv Binding peptides: methods for their generation and use
SE0301936D0 (sv) * 2003-06-30 2003-06-30 Affibody Ab New polypeptide
US7993650B2 (en) 2003-07-04 2011-08-09 Affibody Ab Polypeptides having binding affinity for HER2
JP5634008B2 (ja) 2004-04-06 2014-12-03 アフィボディ・アーベー 新規の使用および方法
EP2066419B1 (en) 2006-09-29 2015-11-11 GE Healthcare Bio-Sciences AB Chromatography ligand comprising domain c from staphyloccocus aureus protein a for antibody isolation
CA2694139C (en) * 2007-07-31 2018-06-05 Affibody Ab Albumin binding polypeptide compositions
GB2452301A (en) 2007-08-30 2009-03-04 Ge Healthcare Bio Sciences Ab Sterilization Method
US8592555B2 (en) * 2008-08-11 2013-11-26 Emd Millipore Corporation Immunoglobulin-binding proteins with improved specificity
CN102165312B (zh) * 2008-09-25 2015-04-22 Jsr株式会社 亲合层析用填充剂
JP5229888B2 (ja) * 2008-09-30 2013-07-03 独立行政法人産業技術総合研究所 弱酸性域での易解離性を向上したプロテインａ変異型タンパク質及び抗体捕捉剤
SG195555A1 (en) * 2008-12-24 2013-12-30 Emd Millipore Corp Caustic stable chromatography ligands
WO2010110288A1 (ja) 2009-03-24 2010-09-30 株式会社カネカ 免疫グロブリンに親和性を有するタンパク質および免疫グロブリン結合性アフィニティーリガンド
SG184184A1 (en) 2010-03-24 2012-10-30 Kaneka Corp Protein capable of binding specifically to immunoglobulin, and immunoglobulin-binding affinity ligand
WO2012086660A1 (ja) 2010-12-21 2012-06-28 Jsr株式会社 アフィニティークロマトグラフィー用担体およびイムノグロブリンを単離する方法
CN103403020A (zh) * 2010-12-21 2013-11-20 Jsr株式会社 蛋白a的新型耐碱变体及其在亲和色谱中的用途
JP6038774B2 (ja) * 2011-03-24 2016-12-07 株式会社カネカ タンパク性物質結合性低分子化合物
WO2012133342A1 (ja) 2011-03-25 2012-10-04 株式会社カネカ 免疫グロブリン結合性新規ポリペプチド
SG186552A1 (en) 2011-06-08 2013-01-30 Emd Millipore Corp Chromatography matrices including novel staphylococcus aureus protein a based ligands
WO2014076177A1 (en) * 2012-11-14 2014-05-22 Affibody Ab New polypeptide
WO2014076179A1 (en) 2012-11-14 2014-05-22 Affibody Ab New polypeptide
USRE48805E1 (en) 2013-03-06 2021-11-02 Vision Global Holdings Ltd. Method for cancer targeting treatment and detection of arginine using albumin-binding arginine deiminase fusion protein
US9255262B2 (en) * 2013-03-06 2016-02-09 Vision Global Holdings Ltd. Albumin-binding arginine deminase and the use thereof
JP6306189B2 (ja) 2013-09-04 2018-04-04 イー・エム・デイー・ミリポア・コーポレイシヨン プロテインａ系親和性クロマトグラフィーカラムを洗浄する方法
EP3050902B1 (en) 2013-09-27 2018-11-21 Kaneka Corporation Process for producing porous cellulose beads using alkali aqueous solution, and porous cellulose beads produced by this process
WO2015088677A1 (en) 2013-12-12 2015-06-18 Emd Millipore Corporation Protein separations using an acrylamide containing filter
JP6369807B2 (ja) * 2014-10-21 2018-08-08 株式会社プロテイン・エクスプレス プロテインｌ変異体
JP6663360B2 (ja) 2015-01-26 2020-03-11 株式会社カネカ 変異型免疫グロブリンκ鎖可変領域結合性ペプチド
WO2016121701A1 (ja) 2015-01-26 2016-08-04 株式会社カネカ 免疫グロブリンκ鎖可変領域含有タンパク質精製用アフィニティー分離マトリックス
EP3276002B1 (en) 2015-03-26 2020-04-29 JSR Corporation Immunoglobulin-binding protein and affinity carrier using same
EP3283508B1 (en) 2015-04-17 2021-03-17 Alpine Immune Sciences, Inc. Immunomodulatory proteins with tunable affinities
US11208441B2 (en) 2015-10-22 2021-12-28 Protenova Co., Ltd. Immunoglobulin-binding polypeptide
WO2017191748A1 (ja) * 2016-05-02 2017-11-09 株式会社カネカ 改変型免疫グロブリンκ鎖可変領域結合性ペプチド
WO2017195638A1 (ja) 2016-05-09 2017-11-16 株式会社カネカ 抗体またはκ鎖可変領域含有抗体断片の精製方法
US11660550B2 (en) 2017-03-07 2023-05-30 Jmva Biotech Ab Modified adsorptive surfaces
TWI888342B (zh) 2017-09-25 2025-07-01 日商Ｊｓｒ股份有限公司 免疫球蛋白結合蛋白質，及使用其之親和性載體
BR112020020604A2 (pt) 2018-04-11 2021-01-12 Inhibrx, Inc. Construções de polipeptídeo multiespecífico tendo ligação restrita de cd3 e métodos e usos relacionados
EP3842536A4 (en) 2018-08-24 2023-01-18 JSR Corporation IMMUNOGLOBULIN-BINDING PROTEIN AND AFFINITY CARRIER WITH IT
US20240026344A1 (en) 2020-10-13 2024-01-25 Avitide LLC Affinity ligand libraries of three-helix bundle proteins and uses thereof
WO2022138718A1 (ja) 2020-12-22 2022-06-30 プロテノバ株式会社 イムノグロブリン結合ポリペプチド
CN117241866A (zh) 2021-02-19 2023-12-15 艾维泰有限责任公司 Aav2亲和剂
GB2609185A (en) 2021-05-24 2023-02-01 Astrea Uk Services Ltd Scaffold for isolation of a biomolecule
EP4541814A1 (en) * 2023-10-20 2025-04-23 Cytiva BioProcess R&D AB Stabilized polypeptides

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Also Published As

Publication number Publication date
EP1123389A1 (en) 2001-08-16
CA2633345A1 (en) 2000-04-27
DE69927598T2 (de) 2006-07-13
JP2002527107A (ja) 2002-08-27
CA2347960C (en) 2008-08-05
CA2347960A1 (en) 2000-04-27
ZA200103252B (en) 2002-07-22
NO323994B1 (no) 2007-07-30
DE69927598D1 (de) 2006-02-16
NO20011969L (no) 2001-06-19
US20050100970A1 (en) 2005-05-12
ATE305970T1 (de) 2005-10-15
GB9823071D0 (en) 1998-12-16
AU6353299A (en) 2000-05-08
DK1123389T3 (da) 2006-01-16
CA2633345C (en) 2013-02-26
EP1672068A1 (en) 2006-06-21
AU773368B2 (en) 2004-05-20
WO2000023580A1 (en) 2000-04-27
EP1123389B1 (en) 2005-10-05
NO20011969D0 (no) 2001-04-20
US6831161B1 (en) 2004-12-14

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