GB9823071D0 - A method - Google Patents

A method

Info

Publication number
GB9823071D0
GB9823071D0 GBGB9823071.7A GB9823071A GB9823071D0 GB 9823071 D0 GB9823071 D0 GB 9823071D0 GB 9823071 A GB9823071 A GB 9823071A GB 9823071 D0 GB9823071 D0 GB 9823071D0
Authority
GB
United Kingdom
Prior art keywords
protein
asn
residues
randomisation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB9823071.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AFFIBODY TECHNOLOGY AB
Original Assignee
AFFIBODY TECHNOLOGY AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AFFIBODY TECHNOLOGY AB filed Critical AFFIBODY TECHNOLOGY AB
Priority to GBGB9823071.7A priority Critical patent/GB9823071D0/en
Publication of GB9823071D0 publication Critical patent/GB9823071D0/en
Priority to JP2000577291A priority patent/JP4801258B2/ja
Priority to AT99950942T priority patent/ATE305970T1/de
Priority to EP99950942A priority patent/EP1123389B1/en
Priority to CA2633345A priority patent/CA2633345C/en
Priority to EP05077192A priority patent/EP1672068A1/en
Priority to US09/830,080 priority patent/US6831161B1/en
Priority to AU63532/99A priority patent/AU773368B2/en
Priority to DE69927598T priority patent/DE69927598T2/de
Priority to CA002347960A priority patent/CA2347960C/en
Priority to PCT/GB1999/003484 priority patent/WO2000023580A1/en
Priority to DK99950942T priority patent/DK1123389T3/da
Priority to NO20011969A priority patent/NO323994B1/no
Priority to ZA200103252A priority patent/ZA200103252B/en
Priority to US11/000,747 priority patent/US20050100970A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GBGB9823071.7A 1998-10-21 1998-10-21 A method Ceased GB9823071D0 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
GBGB9823071.7A GB9823071D0 (en) 1998-10-21 1998-10-21 A method
DK99950942T DK1123389T3 (da) 1998-10-21 1999-10-21 Fremgangsmåde til affinitetsseparation samt ligander til anvendelse derved
US09/830,080 US6831161B1 (en) 1998-10-21 1999-10-21 Method of affinity separation and ligands for use therein
DE69927598T DE69927598T2 (de) 1998-10-21 1999-10-21 Verfahren zur Affinitätstrennung und Liganden zur pertinenten Verwendung
EP99950942A EP1123389B1 (en) 1998-10-21 1999-10-21 A method of affinity separation and ligands for use therein
CA2633345A CA2633345C (en) 1998-10-21 1999-10-21 A method of affinity separation and ligands for use therein
EP05077192A EP1672068A1 (en) 1998-10-21 1999-10-21 A method of affinity separation and ligands for use therein
JP2000577291A JP4801258B2 (ja) 1998-10-21 1999-10-21 アフィニティ分離の方法及びそれに用いるリガンド
AU63532/99A AU773368B2 (en) 1998-10-21 1999-10-21 A method of affinity separation and ligands for use therein
AT99950942T ATE305970T1 (de) 1998-10-21 1999-10-21 Verfahren zur affinitätstrennung und ligande zur pertinenten verwendung
CA002347960A CA2347960C (en) 1998-10-21 1999-10-21 A method of affinity separation and ligands for use therein
PCT/GB1999/003484 WO2000023580A1 (en) 1998-10-21 1999-10-21 A method of affinity separation and ligands for use therein
ZA200103252A ZA200103252B (en) 1998-10-21 2001-04-20 A method of affinity separation and ligands for use therein.
NO20011969A NO323994B1 (no) 1998-10-21 2001-04-20 Fremgangsmate for affinitetsseparasjon, samt albuminbindingsprotein, fusjonsprotein, nukleinsyremolekyl og vertscelle.
US11/000,747 US20050100970A1 (en) 1998-10-21 2004-12-01 Method of affinity separation and ligands for use therein

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9823071.7A GB9823071D0 (en) 1998-10-21 1998-10-21 A method

Publications (1)

Publication Number Publication Date
GB9823071D0 true GB9823071D0 (en) 1998-12-16

Family

ID=10841043

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9823071.7A Ceased GB9823071D0 (en) 1998-10-21 1998-10-21 A method

Country Status (12)

Country Link
US (2) US6831161B1 (https=)
EP (2) EP1672068A1 (https=)
JP (1) JP4801258B2 (https=)
AT (1) ATE305970T1 (https=)
AU (1) AU773368B2 (https=)
CA (2) CA2633345C (https=)
DE (1) DE69927598T2 (https=)
DK (1) DK1123389T3 (https=)
GB (1) GB9823071D0 (https=)
NO (1) NO323994B1 (https=)
WO (1) WO2000023580A1 (https=)
ZA (1) ZA200103252B (https=)

Families Citing this family (45)

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SE0200943D0 (sv) * 2002-03-25 2002-03-25 Amersham Biosciences Ab Mutant protein
US7709209B2 (en) 2002-03-25 2010-05-04 Ge Healthcare Bio-Sciences Ab Protein ligands
GB0214007D0 (en) * 2002-06-18 2002-07-31 Common Services Agency Removal of prion infectivity
AU2004245429A1 (en) * 2003-06-10 2004-12-16 Farallone Holding Bv Binding peptides: methods for their generation and use
SE0301936D0 (sv) * 2003-06-30 2003-06-30 Affibody Ab New polypeptide
US7993650B2 (en) 2003-07-04 2011-08-09 Affibody Ab Polypeptides having binding affinity for HER2
JP5634008B2 (ja) 2004-04-06 2014-12-03 アフィボディ・アーベー 新規の使用および方法
EP2066419B1 (en) 2006-09-29 2015-11-11 GE Healthcare Bio-Sciences AB Chromatography ligand comprising domain c from staphyloccocus aureus protein a for antibody isolation
CA2694139C (en) * 2007-07-31 2018-06-05 Affibody Ab Albumin binding polypeptide compositions
GB2452301A (en) 2007-08-30 2009-03-04 Ge Healthcare Bio Sciences Ab Sterilization Method
US8592555B2 (en) * 2008-08-11 2013-11-26 Emd Millipore Corporation Immunoglobulin-binding proteins with improved specificity
CN102165312B (zh) * 2008-09-25 2015-04-22 Jsr株式会社 亲合层析用填充剂
JP5229888B2 (ja) * 2008-09-30 2013-07-03 独立行政法人産業技術総合研究所 弱酸性域での易解離性を向上したプロテインａ変異型タンパク質及び抗体捕捉剤
SG195555A1 (en) * 2008-12-24 2013-12-30 Emd Millipore Corp Caustic stable chromatography ligands
WO2010110288A1 (ja) 2009-03-24 2010-09-30 株式会社カネカ 免疫グロブリンに親和性を有するタンパク質および免疫グロブリン結合性アフィニティーリガンド
SG184184A1 (en) 2010-03-24 2012-10-30 Kaneka Corp Protein capable of binding specifically to immunoglobulin, and immunoglobulin-binding affinity ligand
WO2012086660A1 (ja) 2010-12-21 2012-06-28 Jsr株式会社 アフィニティークロマトグラフィー用担体およびイムノグロブリンを単離する方法
CN103403020A (zh) * 2010-12-21 2013-11-20 Jsr株式会社 蛋白a的新型耐碱变体及其在亲和色谱中的用途
JP6038774B2 (ja) * 2011-03-24 2016-12-07 株式会社カネカ タンパク性物質結合性低分子化合物
WO2012133342A1 (ja) 2011-03-25 2012-10-04 株式会社カネカ 免疫グロブリン結合性新規ポリペプチド
SG186552A1 (en) 2011-06-08 2013-01-30 Emd Millipore Corp Chromatography matrices including novel staphylococcus aureus protein a based ligands
WO2014076177A1 (en) * 2012-11-14 2014-05-22 Affibody Ab New polypeptide
WO2014076179A1 (en) 2012-11-14 2014-05-22 Affibody Ab New polypeptide
USRE48805E1 (en) 2013-03-06 2021-11-02 Vision Global Holdings Ltd. Method for cancer targeting treatment and detection of arginine using albumin-binding arginine deiminase fusion protein
US9255262B2 (en) * 2013-03-06 2016-02-09 Vision Global Holdings Ltd. Albumin-binding arginine deminase and the use thereof
JP6306189B2 (ja) 2013-09-04 2018-04-04 イー・エム・デイー・ミリポア・コーポレイシヨン プロテインａ系親和性クロマトグラフィーカラムを洗浄する方法
EP3050902B1 (en) 2013-09-27 2018-11-21 Kaneka Corporation Process for producing porous cellulose beads using alkali aqueous solution, and porous cellulose beads produced by this process
WO2015088677A1 (en) 2013-12-12 2015-06-18 Emd Millipore Corporation Protein separations using an acrylamide containing filter
JP6369807B2 (ja) * 2014-10-21 2018-08-08 株式会社プロテイン・エクスプレス プロテインｌ変異体
JP6663360B2 (ja) 2015-01-26 2020-03-11 株式会社カネカ 変異型免疫グロブリンκ鎖可変領域結合性ペプチド
WO2016121701A1 (ja) 2015-01-26 2016-08-04 株式会社カネカ 免疫グロブリンκ鎖可変領域含有タンパク質精製用アフィニティー分離マトリックス
EP3276002B1 (en) 2015-03-26 2020-04-29 JSR Corporation Immunoglobulin-binding protein and affinity carrier using same
EP3283508B1 (en) 2015-04-17 2021-03-17 Alpine Immune Sciences, Inc. Immunomodulatory proteins with tunable affinities
US11208441B2 (en) 2015-10-22 2021-12-28 Protenova Co., Ltd. Immunoglobulin-binding polypeptide
WO2017191748A1 (ja) * 2016-05-02 2017-11-09 株式会社カネカ 改変型免疫グロブリンκ鎖可変領域結合性ペプチド
WO2017195638A1 (ja) 2016-05-09 2017-11-16 株式会社カネカ 抗体またはκ鎖可変領域含有抗体断片の精製方法
US11660550B2 (en) 2017-03-07 2023-05-30 Jmva Biotech Ab Modified adsorptive surfaces
TWI888342B (zh) 2017-09-25 2025-07-01 日商Ｊｓｒ股份有限公司 免疫球蛋白結合蛋白質，及使用其之親和性載體
BR112020020604A2 (pt) 2018-04-11 2021-01-12 Inhibrx, Inc. Construções de polipeptídeo multiespecífico tendo ligação restrita de cd3 e métodos e usos relacionados
EP3842536A4 (en) 2018-08-24 2023-01-18 JSR Corporation IMMUNOGLOBULIN-BINDING PROTEIN AND AFFINITY CARRIER WITH IT
US20240026344A1 (en) 2020-10-13 2024-01-25 Avitide LLC Affinity ligand libraries of three-helix bundle proteins and uses thereof
WO2022138718A1 (ja) 2020-12-22 2022-06-30 プロテノバ株式会社 イムノグロブリン結合ポリペプチド
CN117241866A (zh) 2021-02-19 2023-12-15 艾维泰有限责任公司 Aav2亲和剂
GB2609185A (en) 2021-05-24 2023-02-01 Astrea Uk Services Ltd Scaffold for isolation of a biomolecule
EP4541814A1 (en) * 2023-10-20 2025-04-23 Cytiva BioProcess R&D AB Stabilized polypeptides

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
SE462046C (sv) * 1982-08-23 1998-04-27 Pharmacia Biotech Ab Hybrid-DNA-vektor innehållande DNA-sekvens från Staphylococcus aureus, förfarande för dess framställning och bakterie innehållande densamma
US5401832A (en) * 1984-12-24 1995-03-28 Merck & Co., Inc. Brain derived and recombinant acidic fibroblast growth factor
US5089473A (en) * 1988-08-29 1992-02-18 Monsanto Company Somatotropin variants and their use
WO1993002107A1 (fr) * 1991-07-25 1993-02-04 Oriental Yeast Co., Ltd. Proteine artificielle de combinaison avec les immunoglobulines
JP2584697B2 (ja) * 1991-08-23 1997-02-26 オリエンタル酵母工業株式会社 ＩｇＧ精製用組換え型プロテインＡ
DE59306762D1 (de) * 1992-04-16 1997-07-24 Merck Patent Gmbh Aktivierte Trägermaterialien, ihre Herstellung und Verwendung
SE9400088D0 (sv) * 1994-01-14 1994-01-14 Kabi Pharmacia Ab Bacterial receptor structures
US5736499A (en) * 1995-06-06 1998-04-07 Genencor International, Inc. Mutant A-amylase
SE9503925D0 (sv) * 1995-11-07 1995-11-07 Pharmacia Biotech Ab Separationsmedium för IgG
JP2002508656A (ja) * 1997-03-12 2002-03-19 スミスクライン・ビーチャム・コーポレイション 抗−アルファベータ３ヒト化モノクローナル抗体

Also Published As

Publication number Publication date
EP1123389A1 (en) 2001-08-16
CA2633345A1 (en) 2000-04-27
DE69927598T2 (de) 2006-07-13
JP2002527107A (ja) 2002-08-27
CA2347960C (en) 2008-08-05
JP4801258B2 (ja) 2011-10-26
CA2347960A1 (en) 2000-04-27
ZA200103252B (en) 2002-07-22
NO323994B1 (no) 2007-07-30
DE69927598D1 (de) 2006-02-16
NO20011969L (no) 2001-06-19
US20050100970A1 (en) 2005-05-12
ATE305970T1 (de) 2005-10-15
AU6353299A (en) 2000-05-08
DK1123389T3 (da) 2006-01-16
CA2633345C (en) 2013-02-26
EP1672068A1 (en) 2006-06-21
AU773368B2 (en) 2004-05-20
WO2000023580A1 (en) 2000-04-27
EP1123389B1 (en) 2005-10-05
NO20011969D0 (no) 2001-04-20
US6831161B1 (en) 2004-12-14

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Legal Events

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AT Applications terminated before publication under section 16(1)