NO319448B1 - PTH-analoger, fremgangsmater for deres fremstilling og farmasoytiske preparater inneholdende disse, samt nukleotidsekvenser, ekspresjonsvektorer og vertsceller. - Google Patents
PTH-analoger, fremgangsmater for deres fremstilling og farmasoytiske preparater inneholdende disse, samt nukleotidsekvenser, ekspresjonsvektorer og vertsceller. Download PDFInfo
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- NO319448B1 NO319448B1 NO19950123A NO950123A NO319448B1 NO 319448 B1 NO319448 B1 NO 319448B1 NO 19950123 A NO19950123 A NO 19950123A NO 950123 A NO950123 A NO 950123A NO 319448 B1 NO319448 B1 NO 319448B1
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- Prior art keywords
- ala
- leu
- hpth
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- lys
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- UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Natural products O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 description 1
- 125000003170 phenylsulfonyl group Chemical group C1(=CC=CC=C1)S(=O)(=O)* 0.000 description 1
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- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
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- IWISVGQUKNSOCC-UHFFFAOYSA-K tetramethylazanium;phosphate Chemical compound C[N+](C)(C)C.C[N+](C)(C)C.C[N+](C)(C)C.[O-]P([O-])([O-])=O IWISVGQUKNSOCC-UHFFFAOYSA-K 0.000 description 1
- HNKJADCVZUBCPG-UHFFFAOYSA-N thioanisole Chemical compound CSC1=CC=CC=C1 HNKJADCVZUBCPG-UHFFFAOYSA-N 0.000 description 1
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- 150000003573 thiols Chemical group 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10211—Podoviridae
- C12N2795/10222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929215009A GB9215009D0 (en) | 1992-07-15 | 1992-07-15 | Organic compounds |
| GB929226415A GB9226415D0 (en) | 1992-12-18 | 1992-12-18 | Organic compounds |
| GB929226859A GB9226859D0 (en) | 1992-12-23 | 1992-12-23 | Organic compounds |
| GB929226861A GB9226861D0 (en) | 1992-12-23 | 1992-12-23 | Organic compounds |
| GB939301692A GB9301692D0 (en) | 1993-01-28 | 1993-01-28 | Organic compounds |
| GB939301691A GB9301691D0 (en) | 1993-01-28 | 1993-01-28 | Organic compounds |
| GB939307673A GB9307673D0 (en) | 1993-04-14 | 1993-04-14 | Organic compounds |
| GB939308033A GB9308033D0 (en) | 1993-04-19 | 1993-04-19 | Organic compounds |
| PCT/EP1993/001749 WO1994002510A2 (fr) | 1992-07-15 | 1993-07-06 | Analogues de parathormone |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO950123D0 NO950123D0 (no) | 1995-01-12 |
| NO950123L NO950123L (no) | 1995-03-15 |
| NO319448B1 true NO319448B1 (no) | 2005-08-15 |
Family
ID=27571302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19950123A NO319448B1 (no) | 1992-07-15 | 1995-01-12 | PTH-analoger, fremgangsmater for deres fremstilling og farmasoytiske preparater inneholdende disse, samt nukleotidsekvenser, ekspresjonsvektorer og vertsceller. |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US20050009147A1 (fr) |
| EP (1) | EP0672057B1 (fr) |
| JP (1) | JP3164463B2 (fr) |
| KR (1) | KR100321651B1 (fr) |
| CN (1) | CN1051769C (fr) |
| AT (1) | AT408100B (fr) |
| AU (1) | AU672790B2 (fr) |
| CA (1) | CA2100423C (fr) |
| CH (1) | CH688195A5 (fr) |
| CZ (1) | CZ286889B6 (fr) |
| DE (2) | DE4393381T1 (fr) |
| DK (1) | DK0672057T3 (fr) |
| ES (1) | ES2150948T3 (fr) |
| FI (1) | FI113872B (fr) |
| GB (1) | GB2269176B (fr) |
| GR (1) | GR3035089T3 (fr) |
| HK (1) | HK1004896A1 (fr) |
| HU (2) | HUT70459A (fr) |
| IL (1) | IL106326A (fr) |
| NO (1) | NO319448B1 (fr) |
| NZ (1) | NZ248137A (fr) |
| PT (1) | PT672057E (fr) |
| SG (1) | SG63625A1 (fr) |
| SK (1) | SK283485B6 (fr) |
| WO (1) | WO1994002510A2 (fr) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5814603A (en) * | 1992-06-12 | 1998-09-29 | Affymax Technologies N.V. | Compounds with PTH activity |
| TW273513B (fr) * | 1993-10-27 | 1996-04-01 | Chugai Pharmaceutical Co Ltd | |
| US6110892A (en) * | 1994-06-20 | 2000-08-29 | National Research Council Of Canada | Parathyroid hormone analogues for the treatment of osteoporosis |
| US5955425A (en) * | 1996-08-02 | 1999-09-21 | National Research Council Of Canada | Parathyroid hormone analogues for the treatment of osteoporosis |
| CA2126299C (fr) * | 1994-06-20 | 2000-12-12 | Gordon E. Willick | Analogues de l'hormone parathyroidienne utilises pour le traitement de l'osteoporose |
| CO4410206A1 (es) * | 1994-07-28 | 1997-01-09 | Sandoz Ag | DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN |
| US5747456A (en) * | 1994-12-19 | 1998-05-05 | Beth Israel Deaconess Medical Center | Continuous low-dose administration of parathyroid hormone or its agonist |
| CA2178894A1 (fr) * | 1995-06-15 | 1996-12-16 | Tsunehiko Fukuda | Derives de la parathormone et leur utilisation |
| US6544949B1 (en) | 1995-07-13 | 2003-04-08 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Analogs of parathyroid hormone |
| US5723577A (en) * | 1995-07-13 | 1998-03-03 | Biomeasure Inc. | Analogs of parathyroid hormone |
| US5955574A (en) * | 1995-07-13 | 1999-09-21 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A. | Analogs of parathyroid hormone |
| US7410948B2 (en) | 1995-07-13 | 2008-08-12 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Analogs of parathyroid hormone |
| US5969095A (en) * | 1995-07-13 | 1999-10-19 | Biomeasure, Inc. | Analogs of parathyroid hormone |
| EE9900039A (et) * | 1996-08-02 | 1999-08-16 | National Research Council Of Canada | Paratüreoidhormooni analoogid osteoporoosi raviks |
| EP1352912A1 (fr) * | 1996-08-02 | 2003-10-15 | National Research Council Of Canada | Analogues de l'hormone parathyroidienne pour le traitement de l'osteoporose |
| IL132901A0 (en) | 1997-05-14 | 2001-03-19 | Aventis Pharm Prod Inc | Peptide parathyroid hormone analogs |
| WO1999004808A1 (fr) * | 1997-07-22 | 1999-02-04 | Chugai Seiyaku Kabushiki Kaisha | Medicaments dentaires contenant de la pth |
| EP1005359B1 (fr) * | 1997-09-09 | 2005-06-15 | F. Hoffmann-La Roche Ag | GUERISON DE FRACTURES AU MOYEN D'ANALOGUES DE PTHrP |
| ATE392431T1 (de) | 1998-05-05 | 2008-05-15 | Sod Conseils Rech Applic | Pth2 rezeptor selektive verbindungen |
| WO2000023594A1 (fr) | 1998-10-22 | 2000-04-27 | The General Hospital Corporation | PEPTIDES ET DERIVES PEPTIDIQUES BIOACTIFS DE L'HORMONE PARATHYROIDE (PTH) ET DE LA PROTEINE LIEE A L'HORMONE PARATHYROIDE (PTHrP) |
| DE69942035D1 (de) | 1998-11-25 | 2010-04-01 | Gen Hospital Corp | Menschliches parathyroidhormon, modifikationen, herstellung und verwendung |
| AU2023499A (en) | 1998-12-31 | 2000-07-24 | General Hospital Corporation, The | Pth receptor and screening assay utilizing the same |
| US7057012B1 (en) | 1998-12-31 | 2006-06-06 | The General Hospital Corporation | PTH functional domain conjugate peptides, derivatives thereof and novel tethered ligand-receptor molecules |
| JP2002533115A (ja) * | 1998-12-31 | 2002-10-08 | ザ ジェネラル ホスピタル コーポレーション | Ｐｔｈ機能的ドメイン結合体ペプチド、それらの誘導体、および新規係留リガンド−レセプター分子 |
| US20050272652A1 (en) * | 1999-03-29 | 2005-12-08 | Gault Victor A | Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity |
| DE19916419B4 (de) * | 1999-04-08 | 2005-06-16 | Schering Ag | Kombinationspräparat aus Vitamin-D-Metaboliten oder Vitamin-D-Analoga und einem Östrogenpartialagonisten zur Behandlung von Osteoporose |
| AU7734800A (en) | 1999-09-29 | 2001-04-30 | General Hospital Corporation, The | Polypeptide derivatives of parathyroid hormone (pth) |
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-
1993
- 1993-06-29 AU AU41566/93A patent/AU672790B2/en not_active Ceased
- 1993-07-06 PT PT93915814T patent/PT672057E/pt unknown
- 1993-07-06 DK DK93915814T patent/DK0672057T3/da active
- 1993-07-06 CH CH00784/94A patent/CH688195A5/de not_active IP Right Cessation
- 1993-07-06 HU HU9500115A patent/HUT70459A/hu unknown
- 1993-07-06 DE DE4393381T patent/DE4393381T1/de not_active Withdrawn
- 1993-07-06 DE DE4393381A patent/DE4393381B4/de not_active Expired - Lifetime
- 1993-07-06 SK SK43-95A patent/SK283485B6/sk unknown
- 1993-07-06 AT AT0903993A patent/AT408100B/de not_active IP Right Cessation
- 1993-07-06 WO PCT/EP1993/001749 patent/WO1994002510A2/fr active IP Right Grant
- 1993-07-06 EP EP93915814A patent/EP0672057B1/fr not_active Expired - Lifetime
- 1993-07-06 CZ CZ199588A patent/CZ286889B6/cs not_active IP Right Cessation
- 1993-07-06 ES ES93915814T patent/ES2150948T3/es not_active Expired - Lifetime
- 1993-07-12 GB GB9314384A patent/GB2269176B/en not_active Expired - Fee Related
- 1993-07-12 SG SG1996008052A patent/SG63625A1/en unknown
- 1993-07-13 NZ NZ248137A patent/NZ248137A/en not_active IP Right Cessation
- 1993-07-13 CA CA002100423A patent/CA2100423C/fr not_active Expired - Fee Related
- 1993-07-13 IL IL106326A patent/IL106326A/xx not_active IP Right Cessation
- 1993-07-14 KR KR1019930013440A patent/KR100321651B1/ko not_active IP Right Cessation
- 1993-07-14 JP JP17416393A patent/JP3164463B2/ja not_active Expired - Fee Related
- 1993-07-14 CN CN93116483A patent/CN1051769C/zh not_active Expired - Fee Related
-
1995
- 1995-01-12 NO NO19950123A patent/NO319448B1/no unknown
- 1995-01-13 FI FI950171A patent/FI113872B/fi not_active IP Right Cessation
- 1995-06-21 HU HU95P/P00320P patent/HU211856A9/hu unknown
-
1998
- 1998-05-12 HK HK98104077A patent/HK1004896A1/xx not_active IP Right Cessation
-
2000
- 2000-12-15 GR GR20000402777T patent/GR3035089T3/el unknown
-
2004
- 2004-05-18 US US10/848,279 patent/US20050009147A1/en not_active Abandoned
-
2008
- 2008-07-08 US US12/169,134 patent/US20080318838A1/en not_active Abandoned
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