NO317674B1 - Flytende ekstrakter av haibrusk og sammensetninger derav som har anti-angiogen aktivitet og en virkning pa tumorregresjon, og fremgangsmate til fremstilling derav - Google Patents
Flytende ekstrakter av haibrusk og sammensetninger derav som har anti-angiogen aktivitet og en virkning pa tumorregresjon, og fremgangsmate til fremstilling derav Download PDFInfo
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- NO317674B1 NO317674B1 NO19964547A NO964547A NO317674B1 NO 317674 B1 NO317674 B1 NO 317674B1 NO 19964547 A NO19964547 A NO 19964547A NO 964547 A NO964547 A NO 964547A NO 317674 B1 NO317674 B1 NO 317674B1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Marine Sciences & Fisheries (AREA)
- Dermatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23401994A | 1994-04-28 | 1994-04-28 | |
| US08/384,555 US5618925A (en) | 1994-04-28 | 1995-02-03 | Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof |
| PCT/CA1995/000233 WO1995032722A1 (en) | 1994-04-28 | 1995-04-21 | Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO964547D0 NO964547D0 (no) | 1996-10-25 |
| NO964547L NO964547L (no) | 1996-12-30 |
| NO317674B1 true NO317674B1 (no) | 2004-11-29 |
Family
ID=26927471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19964547A NO317674B1 (no) | 1994-04-28 | 1996-10-25 | Flytende ekstrakter av haibrusk og sammensetninger derav som har anti-angiogen aktivitet og en virkning pa tumorregresjon, og fremgangsmate til fremstilling derav |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US5618925A (ko) |
| EP (1) | EP0759765B1 (ko) |
| JP (1) | JPH09512563A (ko) |
| KR (1) | KR100378787B1 (ko) |
| CN (2) | CN1147305C (ko) |
| AT (1) | ATE224198T1 (ko) |
| BG (1) | BG62954B1 (ko) |
| BR (1) | BR9507552A (ko) |
| CA (1) | CA2188793C (ko) |
| CZ (1) | CZ290520B6 (ko) |
| DE (1) | DE69528258T2 (ko) |
| DK (1) | DK0759765T3 (ko) |
| ES (1) | ES2182900T3 (ko) |
| FI (1) | FI117375B (ko) |
| HU (1) | HU220784B1 (ko) |
| IS (1) | IS1975B (ko) |
| NO (1) | NO317674B1 (ko) |
| NZ (1) | NZ284407A (ko) |
| PL (1) | PL181981B1 (ko) |
| PT (1) | PT759765E (ko) |
| RO (1) | RO114868B1 (ko) |
| RU (1) | RU2156132C2 (ko) |
| SI (1) | SI0759765T1 (ko) |
| WO (1) | WO1995032722A1 (ko) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6028118A (en) * | 1996-08-08 | 2000-02-22 | Les Laboratoires Aeterna Inc. | Methods of using extracts of shark cartilage |
| US6380366B1 (en) * | 1994-04-28 | 2002-04-30 | Les Laboratoires Aeterna Inc. | Shark cartilage extract:process of making, methods of using and compositions thereof |
| US5618925A (en) * | 1994-04-28 | 1997-04-08 | Les Laboratories Aeterna Inc. | Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof |
| US6025334A (en) * | 1994-04-28 | 2000-02-15 | Les Laboratoires Aeterna Inc. | Extracts of shark cartilage having anti-collagenolytic, anti-inflammatory, anti-angiogenic and anti-tumoral activities; process of making, methods of using and compositions thereof |
| CZ292627B6 (cs) * | 1995-02-03 | 2003-11-12 | Les Laboratoires Aeterna Inc. | Léčivo pro léčení nemocí nebo poruch majících složku kolagenolytickou nebo zánětlivou |
| US5843920A (en) * | 1996-09-16 | 1998-12-01 | Biocell Technology, Llc | Anionic saccharides for extraction of anti-angiogenic protein from cartilage |
| AU6639898A (en) * | 1997-02-20 | 1998-09-09 | Industrial Research Limited | Angiogenesis inhibitors and activators from shark cartilage |
| RU2195946C2 (ru) * | 1997-03-11 | 2003-01-10 | Ле Лабораториз Аетерна Инк. | Противоопухолевые терапевтические средства, включающие комбинацию экстракта хряща и антинеопластического агента, обеспечивающие высокую эффективность действия при низких токсических побочных эффектах |
| AU8379098A (en) * | 1997-07-11 | 1999-02-08 | Cv Technologies Inc. | A preparation derived from shark cartilage for treatment of diseases related to excessive phf or excessive intracellular calcium |
| US5840342A (en) * | 1997-09-17 | 1998-11-24 | Raithaus; Lawrence R. | Shark liver extract for stimulating the immune system |
| FR2778558B1 (fr) | 1998-05-12 | 2001-02-16 | Oreal | Utilisation d'inhibiteur de metalloproteinases pour induire et/ou stimuler la croissance des cheveux ou des poils et/ou freiner leur chute |
| PT1520588E (pt) | 1998-07-13 | 2015-03-31 | Univ Texas | Usos de anticorpos para amino fosfolípidos para o tratamento do cancro |
| US6168807B1 (en) | 1998-07-23 | 2001-01-02 | Les Laboratoires Aeterna Inc. | Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof |
| US20020009501A1 (en) * | 1998-07-23 | 2002-01-24 | Eric Dupont | Preparation of cartilage extracts using organic solvents |
| SI1107795T1 (en) | 1998-09-04 | 2003-06-30 | The Regents Of The University Of Michigan | Thiomolybdate associated with at least one carbohydrate, and its use for preventing or treating diseases characterized by aberrant vascularization, such as cancer, wet type macular degeneration, rheumatoid arthritis |
| CN1064690C (zh) * | 1998-09-10 | 2001-04-18 | 中国人民解放军海军医学研究所 | 鲨鱼软骨血管生成抑制因子及其分离纯化方法 |
| US7361643B2 (en) | 2000-02-09 | 2008-04-22 | University Of Puerto Rico | Methods for inhibiting angiogenesis |
| US20040009233A1 (en) * | 2000-12-20 | 2004-01-15 | Davis Paul Frank | Shark meat extract |
| AUPR222300A0 (en) * | 2000-12-21 | 2001-01-25 | Life Therapeutics Limited | Electrophoresis device and method |
| US20030095981A1 (en) * | 2001-05-30 | 2003-05-22 | Kin-Ping Wong | Compositions containing an active fraction isolated from ganoderma lucidum and methods of use |
| US20030087830A1 (en) * | 2001-06-12 | 2003-05-08 | Eric Dupont | Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof |
| US7309501B2 (en) * | 2001-06-21 | 2007-12-18 | Mote Marine Laboratory | Conditioned media to inhibit growth of tumor cells |
| US6908627B2 (en) * | 2001-06-21 | 2005-06-21 | Mote Marine Laboratory | Conditioned media for inhibiting growth of tumor cells |
| WO2003068249A1 (en) | 2002-02-15 | 2003-08-21 | Ocean Nutrition Canada Limited | Shark cartilage extracts and use thereof for immunomodulation |
| NZ537690A (en) | 2002-07-15 | 2009-07-31 | Univ Texas | Antibodies binding to anionic phospholipids and aminophospholipids and their use in treating viral infections |
| EP1614697A4 (en) * | 2003-03-20 | 2007-10-10 | Hosokawa Micron Kk | FROM CORTAR FISH ISOLATED PROTEOGLYKAN AND METHOD OF MANUFACTURING THEREOF |
| US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
| US7901457B2 (en) * | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
| ES2223291B1 (es) * | 2003-08-06 | 2006-03-16 | Bioiberica, S.A. | Nuevo uso terapeutico de condroitin sulfato. |
| ES2403357T3 (es) | 2003-12-11 | 2013-05-17 | Isto Technologies Inc. | Sistema de cartílago particulado |
| ME01881B (me) | 2004-01-22 | 2014-12-20 | Univ Miami | Topijske formulacije koenzima q10 i postupci upotrebe |
| CN100377741C (zh) * | 2004-02-23 | 2008-04-02 | 江卫世 | 注射用复方骨肽及其制备工艺 |
| US20050288796A1 (en) * | 2004-06-23 | 2005-12-29 | Hani Awad | Native soft tissue matrix for therapeutic applications |
| US7837740B2 (en) * | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
| US20090319045A1 (en) | 2004-10-12 | 2009-12-24 | Truncale Katherine G | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
| WO2006059236A2 (en) * | 2004-11-16 | 2006-06-08 | Aeterna Zentaris Inc. | Method of using cartilage extract for increasing blood parameters |
| US7815926B2 (en) * | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
| JP5292533B2 (ja) | 2005-08-26 | 2013-09-18 | ジンマー・インコーポレイテッド | インプラントおよび関節疾患の治療、置換および治療方法 |
| WO2007035778A2 (en) | 2005-09-19 | 2007-03-29 | Histogenics Corporation | Cell-support matrix and a method for preparation thereof |
| DE102006060247A1 (de) * | 2006-09-15 | 2008-03-27 | Ossacur Ag | Differenzierung von Stammzellen |
| US8163549B2 (en) | 2006-12-20 | 2012-04-24 | Zimmer Orthobiologics, Inc. | Method of obtaining viable small tissue particles and use for tissue repair |
| US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
| WO2008128075A1 (en) | 2007-04-12 | 2008-10-23 | Isto Technologies, Inc. | Compositions and methods for tissue repair |
| KR101502267B1 (ko) | 2007-11-09 | 2015-03-18 | 페레그린 파마수티컬즈, 인크 | 항-ｖｅｇｆ 항체 조성물 및 방법 |
| CA2749750C (en) * | 2008-04-15 | 2014-01-28 | Immanence Integrale Dermo Correction Inc. | Skin care compositions and methods of use thereof |
| CA2737146A1 (en) | 2008-07-25 | 2010-01-28 | The Regents Of The University Of Colorado | Clip inhibitors and methods of modulating immune function |
| US20100274362A1 (en) * | 2009-01-15 | 2010-10-28 | Avner Yayon | Cartilage particle tissue mixtures optionally combined with a cancellous construct |
| CN101891811B (zh) * | 2010-05-28 | 2011-11-09 | 暨南大学 | 一种鲨鱼血管生成抑制因子及其生产纯化方法和应用 |
| CN101899104B (zh) * | 2010-05-28 | 2012-04-18 | 暨南大学 | 一种鲨鱼软骨血管生成抑制因子小分子多肽及其生产纯化方法和应用 |
| US9284359B2 (en) * | 2011-01-19 | 2016-03-15 | Hirosaki University | Method for mass preparation of proteoglycan |
| US20140178343A1 (en) | 2012-12-21 | 2014-06-26 | Jian Q. Yao | Supports and methods for promoting integration of cartilage tissue explants |
| US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
| CN104894200B (zh) * | 2015-05-12 | 2020-10-30 | 浙江海洋学院 | 路氏双髻鲨软骨血管生成抑制因子的制备方法 |
| KR101628982B1 (ko) | 2015-11-27 | 2016-06-09 | 김준혁 | 항종양 및 면역 증강용 건강식품 조성물 |
| US10786471B2 (en) | 2017-02-06 | 2020-09-29 | Massachusetts Institute Of Technology | Methods and products related to glutaminase inhibitors |
| CN109394786A (zh) * | 2018-10-26 | 2019-03-01 | 西交利物浦大学 | 一种抗肿瘤的药物组合物 |
| WO2020203812A1 (ja) * | 2019-03-29 | 2020-10-08 | 学校法人慶應義塾 | 魚介類由来成分による低酸素応答制御 |
| US20220241323A1 (en) * | 2019-06-14 | 2022-08-04 | "l2LIFE" LIMITED LIABILITY COMPANY("I2LIFE"LLC) | Method for the production of iodinated proteins with a determinated iodine content |
| CN112986499A (zh) * | 2021-02-26 | 2021-06-18 | 山西奥瑞生物材料有限公司 | 一种同种骨植入材料残余水量均匀度测定方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3478146A (en) * | 1965-02-26 | 1969-11-11 | Leslie L Balassa | Wound-healing cartilage powder extracting process |
| US4042457A (en) * | 1975-11-10 | 1977-08-16 | Rush-Presbyterian-St. Luke's Medical Center | Preparation of tissue invasion inhibitor and method of treatment utilizing the inhibitor |
| US4822607A (en) * | 1976-10-29 | 1989-04-18 | Lescarden Ltd. | Anti-tumor agent and method |
| US4243582A (en) * | 1979-04-26 | 1981-01-06 | Monsanto Company | Novel glycoproteins from bovine cartilage |
| US4350682A (en) * | 1979-05-11 | 1982-09-21 | Lescarden Ltd. | Cartilage extraction processes and products |
| US4356261A (en) * | 1980-04-22 | 1982-10-26 | Rush-Presbyterian-St. Luke's Medical Center | Anti-invasion factor containing cultures |
| US4473551A (en) * | 1982-08-23 | 1984-09-25 | Faxon Pharmaceuticals, Inc. | Anti-inflammatory composition |
| US4656137A (en) * | 1985-09-12 | 1987-04-07 | Lescarden Inc | Method of processing animal cartilage |
| US4749522A (en) * | 1985-10-31 | 1988-06-07 | Angio-Medical Corporation | Supercritical fluid extraction of animal derived materials |
| US4746729A (en) * | 1986-07-30 | 1988-05-24 | Kuettner Klaus E | Cartilage-derived leukocyte elastase-inhibitor |
| US5075112A (en) * | 1990-02-12 | 1991-12-24 | Cartilage Technologies Inc. | Method of and dosage unit for inhibiting angiogenesis or vascularization in an animal using shark cartilage |
| WO1994012510A1 (en) * | 1992-11-30 | 1994-06-09 | Lane I William | Processing shark cartilage |
| DE69435342D1 (de) * | 1993-07-19 | 2011-05-05 | Angiotech Pharm Inc | Anti-Angiogene Mittel und Verfahren zu deren Verwendung |
| US5618925A (en) * | 1994-04-28 | 1997-04-08 | Les Laboratories Aeterna Inc. | Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof |
-
1995
- 1995-02-03 US US08/384,555 patent/US5618925A/en not_active Expired - Lifetime
- 1995-04-21 PL PL95317076A patent/PL181981B1/pl not_active IP Right Cessation
- 1995-04-21 CA CA002188793A patent/CA2188793C/en not_active Expired - Lifetime
- 1995-04-21 DE DE69528258T patent/DE69528258T2/de not_active Expired - Lifetime
- 1995-04-21 SI SI9530630T patent/SI0759765T1/xx unknown
- 1995-04-21 KR KR1019960706077A patent/KR100378787B1/ko not_active IP Right Cessation
- 1995-04-21 ES ES95916523T patent/ES2182900T3/es not_active Expired - Lifetime
- 1995-04-21 CN CNB951934368A patent/CN1147305C/zh not_active Expired - Lifetime
- 1995-04-21 CZ CZ19963141A patent/CZ290520B6/cs not_active IP Right Cessation
- 1995-04-21 NZ NZ284407A patent/NZ284407A/en unknown
- 1995-04-21 EP EP95916523A patent/EP0759765B1/en not_active Expired - Lifetime
- 1995-04-21 CN CNA2004100397718A patent/CN1541656A/zh active Pending
- 1995-04-21 RU RU96123763/14A patent/RU2156132C2/ru active
- 1995-04-21 JP JP8500104A patent/JPH09512563A/ja active Pending
- 1995-04-21 WO PCT/CA1995/000233 patent/WO1995032722A1/en active IP Right Grant
- 1995-04-21 RO RO96-02058A patent/RO114868B1/ro unknown
- 1995-04-21 BR BR9507552A patent/BR9507552A/pt not_active Application Discontinuation
- 1995-04-21 HU HU9602975A patent/HU220784B1/hu not_active IP Right Cessation
- 1995-04-21 AT AT95916523T patent/ATE224198T1/de active
- 1995-04-21 DK DK95916523T patent/DK0759765T3/da active
- 1995-04-21 PT PT95916523T patent/PT759765E/pt unknown
-
1996
- 1996-10-08 US US08/727,300 patent/US5985839A/en not_active Expired - Lifetime
- 1996-10-25 NO NO19964547A patent/NO317674B1/no unknown
- 1996-10-25 IS IS4379A patent/IS1975B/is unknown
- 1996-10-28 FI FI964327A patent/FI117375B/fi active IP Right Grant
- 1996-10-28 BG BG100941A patent/BG62954B1/bg unknown
Also Published As
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| NO317674B1 (no) | Flytende ekstrakter av haibrusk og sammensetninger derav som har anti-angiogen aktivitet og en virkning pa tumorregresjon, og fremgangsmate til fremstilling derav | |
| US6025334A (en) | Extracts of shark cartilage having anti-collagenolytic, anti-inflammatory, anti-angiogenic and anti-tumoral activities; process of making, methods of using and compositions thereof | |
| FI117376B (fi) | Hainrustouutteiden käyttö valmistettaessa lääkettä kollagenolyysi- tai tulehdustekijän sisältävän sairauden hoitamiseksi | |
| AU719118C (en) | Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof | |
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