NO314604B1 - Deteksjon av syndekaninnholdet i biologisk materiale så som vevs- og kroppsv¶sker for angivelse av malign transformasjon av celler - Google Patents
Deteksjon av syndekaninnholdet i biologisk materiale så som vevs- og kroppsv¶sker for angivelse av malign transformasjon av celler Download PDFInfo
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- NO314604B1 NO314604B1 NO19932552A NO932552A NO314604B1 NO 314604 B1 NO314604 B1 NO 314604B1 NO 19932552 A NO19932552 A NO 19932552A NO 932552 A NO932552 A NO 932552A NO 314604 B1 NO314604 B1 NO 314604B1
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- syndecan
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- 210000000981 epithelium Anatomy 0.000 description 1
- 230000003328 fibroblastic effect Effects 0.000 description 1
- MHMNJMPURVTYEJ-UHFFFAOYSA-N fluorescein-5-isothiocyanate Chemical compound O1C(=O)C2=CC(N=C=S)=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 MHMNJMPURVTYEJ-UHFFFAOYSA-N 0.000 description 1
- 102000037865 fusion proteins Human genes 0.000 description 1
- 108020001507 fusion proteins Proteins 0.000 description 1
- 108020004445 glyceraldehyde-3-phosphate dehydrogenase Proteins 0.000 description 1
- -1 glycosamine glycan Chemical class 0.000 description 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 238000001794 hormone therapy Methods 0.000 description 1
- 210000004293 human mammary gland Anatomy 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 230000000984 immunochemical effect Effects 0.000 description 1
- 230000002055 immunohistochemical effect Effects 0.000 description 1
- 238000007901 in situ hybridization Methods 0.000 description 1
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- 238000011065 in-situ storage Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 102000006495 integrins Human genes 0.000 description 1
- 108010044426 integrins Proteins 0.000 description 1
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- 238000002955 isolation Methods 0.000 description 1
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- 230000037311 normal skin Effects 0.000 description 1
- 231100000590 oncogenic Toxicity 0.000 description 1
- 230000002246 oncogenic effect Effects 0.000 description 1
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- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000003076 paracrine Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000004963 pathophysiological condition Effects 0.000 description 1
- KHIWWQKSHDUIBK-UHFFFAOYSA-N periodic acid Chemical compound OI(=O)(=O)=O KHIWWQKSHDUIBK-UHFFFAOYSA-N 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 239000000047 product Substances 0.000 description 1
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- 230000006337 proteolytic cleavage Effects 0.000 description 1
- 238000003127 radioimmunoassay Methods 0.000 description 1
- 239000012925 reference material Substances 0.000 description 1
- 230000009703 regulation of cell differentiation Effects 0.000 description 1
- 230000025053 regulation of cell proliferation Effects 0.000 description 1
- 230000034515 regulation of cell shape Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 108020004418 ribosomal RNA Proteins 0.000 description 1
- 235000019515 salmon Nutrition 0.000 description 1
- 229940043230 sarcosine Drugs 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
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- 230000001225 therapeutic effect Effects 0.000 description 1
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- 230000005740 tumor formation Effects 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57469—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving tumor associated glycolinkage, i.e. TAG
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64120991A | 1991-01-15 | 1991-01-15 | |
US72133091A | 1991-07-01 | 1991-07-01 | |
PCT/FI1991/000399 WO1992013274A1 (en) | 1991-01-15 | 1991-12-19 | Detection of syndecan content in biological materials such as tissues and body fluids for indications of malignant transformations of cells |
Publications (3)
Publication Number | Publication Date |
---|---|
NO932552D0 NO932552D0 (no) | 1993-07-14 |
NO932552L NO932552L (no) | 1993-07-14 |
NO314604B1 true NO314604B1 (no) | 2003-04-14 |
Family
ID=27093707
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19932552A NO314604B1 (no) | 1991-01-15 | 1993-07-14 | Deteksjon av syndekaninnholdet i biologisk materiale så som vevs- og kroppsv¶sker for angivelse av malign transformasjon av celler |
Country Status (23)
Country | Link |
---|---|
US (1) | US5422243A (sk) |
EP (2) | EP0569367B1 (sk) |
JP (1) | JP3103377B2 (sk) |
KR (1) | KR0162670B1 (sk) |
AT (1) | ATE166157T1 (sk) |
AU (1) | AU650936B2 (sk) |
BG (1) | BG61625B1 (sk) |
CA (1) | CA2100077C (sk) |
CZ (1) | CZ282203B6 (sk) |
DE (1) | DE69129417T2 (sk) |
DK (1) | DK0569367T3 (sk) |
ES (1) | ES2116331T3 (sk) |
FI (1) | FI104347B1 (sk) |
HU (1) | HU215778B (sk) |
IE (2) | IE990011A1 (sk) |
NO (1) | NO314604B1 (sk) |
NZ (1) | NZ241273A (sk) |
PL (1) | PL168188B1 (sk) |
PT (1) | PT100008B (sk) |
RU (1) | RU2139540C1 (sk) |
SK (1) | SK281583B6 (sk) |
WO (1) | WO1992013274A1 (sk) |
ZA (1) | ZA92271B (sk) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5726058A (en) * | 1992-12-01 | 1998-03-10 | Jalkanen; Markku | Syndecan stimulation of cellular differentiation |
DK0671909T3 (da) * | 1992-12-01 | 2001-03-19 | Biotie Therapies Corp | Syndecanstimulering af cellulær differentiering |
US6017727A (en) * | 1994-03-07 | 2000-01-25 | Biotie Therapies Ltd. | Syndecan enhancer element and syndecan stimulation of cellular differentiation |
US5851993A (en) * | 1994-06-13 | 1998-12-22 | Biotie Therapies Ltd. | Suppression of tumor cell growth by syndecan-1 ectodomain |
GB9519490D0 (en) * | 1995-09-25 | 1995-11-29 | Melvin William T | Use of a cytochrome P450 enzyme in tumour cells as a marker and target |
US6385546B1 (en) | 1996-11-15 | 2002-05-07 | Rutgers, The University Of New Jersey | Stabilizing and destabilizing proteins |
PL196605B1 (pl) * | 1997-08-12 | 2008-01-31 | Leadd Bv | Sposób oznaczania zdolności transformującej, sposób oznaczania predyspozycji do przekształcania się w komórkę nowotworową, sposób oznaczania predyspozycji do dziedziczenia rodzajów raka, sposób oznaczania mutacji genu i diagnostyczny zestaw testowy |
CA2346264A1 (en) * | 1998-10-16 | 2000-04-27 | Regents Of The University Of California | Glypicans for the detection and treatment of human carcinoma |
US6998232B1 (en) * | 1999-09-27 | 2006-02-14 | Quark Biotech, Inc. | Methods of diagnosing bladder cancer |
WO2001077682A1 (fr) * | 2000-04-10 | 2001-10-18 | Institut Bioorganicheskoi Khimii Imeni Akademikov M.M. Shemyakina I Ju. A. Ovchinnikova Rossiisskoi Akademii Nauk | Anticorps diriges contre le facteur hldf, procedes de fabrication correspondants, peptides avec des capacites antigeniques et a hydrolyse hk et procede de diagnostic de l'etat anaplasique de cellules humaines |
WO2002086084A2 (en) * | 2001-04-04 | 2002-10-31 | Quark Biotech, Inc. | Sequence characteristics of bladder cancer |
KR100694804B1 (ko) * | 2005-05-18 | 2007-03-14 | 아주대학교산학협력단 | 작은 헤어핀 rna 분자를 포함하는 자궁 내막암 치료또는 예방용 조성물 및 그를 이용한 자궁 내막암 치료 또는예방 방법 |
US8347890B2 (en) * | 2006-06-19 | 2013-01-08 | Insono Therapeutics, Inc. | Automated tissue retention system |
WO2009105624A2 (en) * | 2008-02-21 | 2009-08-27 | Massachusetts Institute Of Technology | Simultaneous delivery of receptors and/or co-receptors for growth factor stability and activity |
GB0803272D0 (en) * | 2008-02-22 | 2008-04-02 | Smith & Nephew | Ultrasound and tissue repair |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3511199A1 (de) * | 1985-03-28 | 1986-10-02 | Hoechst Ag, 6230 Frankfurt | Verfahren zur immunologischen bestimmung von heparansulfat-proteoglykan, verfahren zur herstellung bzw. reinigung von dafuer geeignetem heparansulfat-proteoglykan aus basalmembran-haltigen geweben |
US4859581A (en) * | 1986-03-10 | 1989-08-22 | Board Of Regents, The University Of Texas System | Endoglycosidase assay |
US4945086A (en) * | 1988-05-03 | 1990-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Smooth muscle cell growth inhibitor |
JPH02156898A (ja) * | 1988-12-08 | 1990-06-15 | Seikagaku Kogyo Co Ltd | 抗低密度型ヘパラン硫酸プロテオグリカンモノクローン抗体、それを産生するハイブリドーマおよびこのモノクローン抗体を用いる低密度型ヘパラン硫酸プロテオグリカンの検出方法 |
WO1990007712A1 (de) * | 1988-12-23 | 1990-07-12 | Bissendorf Peptide Gmbh | Antigen, assoziiert mit degenerativen erscheinungen des zentralen nervensystems (zns), dagegen gerichtete antikörper sowie verfahren zur diagnose von dysfunktionen des zns |
WO1990012033A1 (en) * | 1989-03-29 | 1990-10-18 | The Board Of Trustees Of The Leland Stanford Junior University | Construction and use of synthetic constructs encoding syndecan |
AU2561792A (en) * | 1991-09-06 | 1993-04-05 | Children's Medical Center Corporation | Cell-type specific heparan sulfate proteoglycans and their uses |
-
1991
- 1991-12-19 EP EP92901010A patent/EP0569367B1/en not_active Expired - Lifetime
- 1991-12-19 CZ CS931372A patent/CZ282203B6/cs not_active IP Right Cessation
- 1991-12-19 DK DK92901010T patent/DK0569367T3/da active
- 1991-12-19 WO PCT/FI1991/000399 patent/WO1992013274A1/en active IP Right Grant
- 1991-12-19 JP JP04501685A patent/JP3103377B2/ja not_active Expired - Fee Related
- 1991-12-19 AU AU90713/91A patent/AU650936B2/en not_active Ceased
- 1991-12-19 CA CA002100077A patent/CA2100077C/en not_active Expired - Fee Related
- 1991-12-19 RU RU93051783/14A patent/RU2139540C1/ru not_active IP Right Cessation
- 1991-12-19 HU HU9302030A patent/HU215778B/hu not_active IP Right Cessation
- 1991-12-19 EP EP97116570A patent/EP0816851A3/en not_active Withdrawn
- 1991-12-19 KR KR1019930702128A patent/KR0162670B1/ko not_active IP Right Cessation
- 1991-12-19 SK SK738-93A patent/SK281583B6/sk unknown
- 1991-12-19 AT AT92901010T patent/ATE166157T1/de not_active IP Right Cessation
- 1991-12-19 DE DE69129417T patent/DE69129417T2/de not_active Expired - Fee Related
- 1991-12-19 ES ES92901010T patent/ES2116331T3/es not_active Expired - Lifetime
- 1991-12-19 PL PL91300110A patent/PL168188B1/pl unknown
-
1992
- 1992-01-10 NZ NZ241273A patent/NZ241273A/en unknown
- 1992-01-13 PT PT100008A patent/PT100008B/pt not_active IP Right Cessation
- 1992-01-14 IE IE19990011A patent/IE990011A1/en unknown
- 1992-01-14 IE IE010792A patent/IE920107A1/en unknown
- 1992-01-14 ZA ZA92271A patent/ZA92271B/xx unknown
-
1993
- 1993-07-14 NO NO19932552A patent/NO314604B1/no unknown
- 1993-07-15 BG BG97950A patent/BG61625B1/bg unknown
- 1993-07-15 FI FI933211A patent/FI104347B1/fi active
- 1993-11-01 US US08/144,547 patent/US5422243A/en not_active Expired - Lifetime
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