ES2154290T3 - Estimulacion de la diferenciacion celular por sindecano. - Google Patents
Estimulacion de la diferenciacion celular por sindecano.Info
- Publication number
- ES2154290T3 ES2154290T3 ES94900846T ES94900846T ES2154290T3 ES 2154290 T3 ES2154290 T3 ES 2154290T3 ES 94900846 T ES94900846 T ES 94900846T ES 94900846 T ES94900846 T ES 94900846T ES 2154290 T3 ES2154290 T3 ES 2154290T3
- Authority
- ES
- Spain
- Prior art keywords
- methods
- syndecan
- sindecano
- stimulation
- cell differentiation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
SE DESCRIBEN METODOS PARA ALTERAR LOS NIVELES DE SYNDECAN EN UNA CELULA. LOS METODOS INCLUYEN UNA MEJORA DE LA EXPRESION SYNDECAN A TRAVES DE LA ADMINISTRACION DE FACTORES DE CRECIMIENTO, EVITANDO LA SUPRESION DE UNA EXPRESION SYNDECAN A TRAVES DE LA ADMINISTRACION DE AGENTES ANTIESTEROIDES, Y ALTERANDO LA BIOQUIMICA SYNDECAN EN LA CELULA. LOS METODOS SE UTILIZAN PARA INDUCIR O MANTENER LA DIFERENCIACION CELULAR, Y PARA DISMINUIR EL CRECIMIENTO DE LAS CELULAS MALIGNAS. SE DESCRIBE LA APLICACION DE LOS METODOS PARA EL TRATAMIENTO DE PACIENTES, INCLUYENDO HUMANOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98842792A | 1992-12-01 | 1992-12-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2154290T3 true ES2154290T3 (es) | 2001-04-01 |
Family
ID=25534102
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94900846T Expired - Lifetime ES2154290T3 (es) | 1992-12-01 | 1993-12-01 | Estimulacion de la diferenciacion celular por sindecano. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0671909B1 (es) |
JP (1) | JPH08503848A (es) |
AT (1) | ATE198271T1 (es) |
AU (1) | AU687767B2 (es) |
CA (1) | CA2150714C (es) |
DE (1) | DE69329802T2 (es) |
DK (1) | DK0671909T3 (es) |
ES (1) | ES2154290T3 (es) |
WO (1) | WO1994012162A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5726058A (en) * | 1992-12-01 | 1998-03-10 | Jalkanen; Markku | Syndecan stimulation of cellular differentiation |
US6017727A (en) * | 1994-03-07 | 2000-01-25 | Biotie Therapies Ltd. | Syndecan enhancer element and syndecan stimulation of cellular differentiation |
US6492344B1 (en) | 1993-12-01 | 2002-12-10 | Biotie Therapies Corp. | Syndecan enhancer element and syndecan stimulation of cellular differentiation |
US5851993A (en) * | 1994-06-13 | 1998-12-22 | Biotie Therapies Ltd. | Suppression of tumor cell growth by syndecan-1 ectodomain |
US6413534B1 (en) | 1998-05-07 | 2002-07-02 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
AU2003203589B2 (en) * | 1998-05-07 | 2005-10-27 | The University Of Tennessee Research Corporation | A method for chemoprevention of prostate cancer |
SK16642000A3 (sk) * | 1998-05-07 | 2002-08-06 | The University Of Tennessee Research Corporation | Spôsob chemoprevencie rakoviny prostaty |
US6413533B1 (en) * | 1998-05-07 | 2002-07-02 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
US6632447B1 (en) | 1998-05-07 | 2003-10-14 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8806893D0 (en) * | 1988-03-23 | 1988-04-27 | Unilever Plc | Cosmetic composition |
JPH04224522A (ja) * | 1990-04-27 | 1992-08-13 | Merck & Co Inc | 繊維芽細胞増殖因子含有組成物による禿頭症の治療又は予防方法 |
US5147854A (en) * | 1990-05-22 | 1992-09-15 | Hoffmann-La Roche Inc. | Tgf-b compositions and method |
RU2139540C1 (ru) * | 1991-01-15 | 1999-10-10 | Биоти Терапис Лтд. | Способ обнаружения озлокачествления |
-
1993
- 1993-12-01 ES ES94900846T patent/ES2154290T3/es not_active Expired - Lifetime
- 1993-12-01 AU AU55649/94A patent/AU687767B2/en not_active Ceased
- 1993-12-01 WO PCT/FI1993/000514 patent/WO1994012162A1/en active IP Right Grant
- 1993-12-01 CA CA002150714A patent/CA2150714C/en not_active Expired - Fee Related
- 1993-12-01 DK DK94900846T patent/DK0671909T3/da active
- 1993-12-01 AT AT94900846T patent/ATE198271T1/de not_active IP Right Cessation
- 1993-12-01 JP JP6512818A patent/JPH08503848A/ja active Pending
- 1993-12-01 EP EP94900846A patent/EP0671909B1/en not_active Expired - Lifetime
- 1993-12-01 DE DE69329802T patent/DE69329802T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2150714A1 (en) | 1994-06-09 |
DE69329802D1 (de) | 2001-02-01 |
ATE198271T1 (de) | 2001-01-15 |
EP0671909B1 (en) | 2000-12-27 |
AU5564994A (en) | 1994-06-22 |
WO1994012162A1 (en) | 1994-06-09 |
JPH08503848A (ja) | 1996-04-30 |
DK0671909T3 (da) | 2001-03-19 |
DE69329802T2 (de) | 2001-07-19 |
AU687767B2 (en) | 1998-03-05 |
EP0671909A1 (en) | 1995-09-20 |
CA2150714C (en) | 2002-02-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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