NO314123B1 - Medikamentbeholder av line¶r olefin-polymer for lagring av flytende medikament, og anvendelse av medikamentbeholderen - Google Patents
Medikamentbeholder av line¶r olefin-polymer for lagring av flytende medikament, og anvendelse av medikamentbeholderen Download PDFInfo
- Publication number
- NO314123B1 NO314123B1 NO19993084A NO993084A NO314123B1 NO 314123 B1 NO314123 B1 NO 314123B1 NO 19993084 A NO19993084 A NO 19993084A NO 993084 A NO993084 A NO 993084A NO 314123 B1 NO314123 B1 NO 314123B1
- Authority
- NO
- Norway
- Prior art keywords
- container
- weight
- container according
- cresol
- wall
- Prior art date
Links
- 239000003814 drug Substances 0.000 title claims description 72
- 229940079593 drug Drugs 0.000 title claims description 64
- 238000003860 storage Methods 0.000 title claims description 20
- 229920000098 polyolefin Polymers 0.000 title claims description 16
- 239000007788 liquid Substances 0.000 title claims description 10
- RLSSMJSEOOYNOY-UHFFFAOYSA-N m-cresol Chemical compound CC1=CC=CC(O)=C1 RLSSMJSEOOYNOY-UHFFFAOYSA-N 0.000 claims description 82
- 239000000463 material Substances 0.000 claims description 57
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims description 50
- 229920000642 polymer Polymers 0.000 claims description 44
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 claims description 42
- 230000005540 biological transmission Effects 0.000 claims description 33
- -1 ethylene, propylene, butylene Chemical group 0.000 claims description 32
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 31
- 230000035699 permeability Effects 0.000 claims description 29
- 102000004877 Insulin Human genes 0.000 claims description 25
- 108090001061 Insulin Proteins 0.000 claims description 25
- 229940125396 insulin Drugs 0.000 claims description 25
- 239000004743 Polypropylene Substances 0.000 claims description 21
- 229920001155 polypropylene Polymers 0.000 claims description 21
- 239000000243 solution Substances 0.000 claims description 20
- 239000003755 preservative agent Substances 0.000 claims description 18
- 235000019445 benzyl alcohol Nutrition 0.000 claims description 14
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims description 13
- 239000005977 Ethylene Substances 0.000 claims description 13
- 239000002861 polymer material Substances 0.000 claims description 13
- 239000000203 mixture Substances 0.000 claims description 11
- 239000000654 additive Substances 0.000 claims description 9
- 239000007864 aqueous solution Substances 0.000 claims description 9
- 239000011521 glass Substances 0.000 claims description 8
- 239000000945 filler Substances 0.000 claims description 6
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 claims description 6
- 239000004698 Polyethylene Substances 0.000 claims description 5
- 150000001336 alkenes Chemical class 0.000 claims description 5
- 239000000178 monomer Substances 0.000 claims description 5
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 claims description 5
- 229920000573 polyethylene Polymers 0.000 claims description 5
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 claims description 5
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 4
- 229910052782 aluminium Inorganic materials 0.000 claims description 4
- 239000007900 aqueous suspension Substances 0.000 claims description 4
- 238000000113 differential scanning calorimetry Methods 0.000 claims description 4
- 238000002844 melting Methods 0.000 claims description 4
- 230000008018 melting Effects 0.000 claims description 4
- 239000002667 nucleating agent Substances 0.000 claims description 4
- 239000002245 particle Substances 0.000 claims description 4
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 claims description 4
- 239000004094 surface-active agent Substances 0.000 claims description 4
- 238000005033 Fourier transform infrared spectroscopy Methods 0.000 claims description 3
- 238000002835 absorbance Methods 0.000 claims description 3
- 239000003963 antioxidant agent Substances 0.000 claims description 3
- 239000008395 clarifying agent Substances 0.000 claims description 3
- 238000005520 cutting process Methods 0.000 claims description 3
- 230000009477 glass transition Effects 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 239000000314 lubricant Substances 0.000 claims description 3
- 229920005653 propylene-ethylene copolymer Polymers 0.000 claims description 3
- 239000000725 suspension Substances 0.000 claims description 3
- 102000002265 Human Growth Hormone Human genes 0.000 claims description 2
- 108010000521 Human Growth Hormone Proteins 0.000 claims description 2
- 239000000854 Human Growth Hormone Substances 0.000 claims description 2
- 229920005629 polypropylene homopolymer Polymers 0.000 claims description 2
- 230000004888 barrier function Effects 0.000 description 15
- 239000013078 crystal Substances 0.000 description 9
- 229920001971 elastomer Polymers 0.000 description 8
- 230000000694 effects Effects 0.000 description 7
- 229920005557 bromobutyl Polymers 0.000 description 6
- 230000008859 change Effects 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 229920003023 plastic Polymers 0.000 description 6
- 239000004033 plastic Substances 0.000 description 6
- 230000002335 preservative effect Effects 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 238000011161 development Methods 0.000 description 4
- 239000000122 growth hormone Substances 0.000 description 4
- 238000006116 polymerization reaction Methods 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- 244000043261 Hevea brasiliensis Species 0.000 description 3
- YAJCHEVQCOHZDC-QMMNLEPNSA-N actrapid Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3N=CNC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@H](C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@H](C)CC)[C@H](C)CC)[C@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C(N)=O)C1=CNC=N1 YAJCHEVQCOHZDC-QMMNLEPNSA-N 0.000 description 3
- 238000002425 crystallisation Methods 0.000 description 3
- 230000008025 crystallization Effects 0.000 description 3
- 238000009792 diffusion process Methods 0.000 description 3
- 238000001746 injection moulding Methods 0.000 description 3
- 229920003052 natural elastomer Polymers 0.000 description 3
- 229920001194 natural rubber Polymers 0.000 description 3
- 229920000728 polyester Polymers 0.000 description 3
- 239000004800 polyvinyl chloride Substances 0.000 description 3
- 238000011179 visual inspection Methods 0.000 description 3
- VXNZUUAINFGPBY-UHFFFAOYSA-N 1-Butene Chemical compound CCC=C VXNZUUAINFGPBY-UHFFFAOYSA-N 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 2
- 102000018997 Growth Hormone Human genes 0.000 description 2
- 108010051696 Growth Hormone Proteins 0.000 description 2
- KKEYFWRCBNTPAC-UHFFFAOYSA-N Terephthalic acid Chemical compound OC(=O)C1=CC=C(C(O)=O)C=C1 KKEYFWRCBNTPAC-UHFFFAOYSA-N 0.000 description 2
- CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical class [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 description 2
- 238000005266 casting Methods 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 238000004128 high performance liquid chromatography Methods 0.000 description 2
- 230000002209 hydrophobic effect Effects 0.000 description 2
- 239000012968 metallocene catalyst Substances 0.000 description 2
- 238000005457 optimization Methods 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 229920000915 polyvinyl chloride Polymers 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 235000018102 proteins Nutrition 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- HLWRUJAIJJEZDL-UHFFFAOYSA-M sodium;2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetate Chemical compound [Na+].OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC([O-])=O HLWRUJAIJJEZDL-UHFFFAOYSA-M 0.000 description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 description 1
- 229930064664 L-arginine Natural products 0.000 description 1
- 235000014852 L-arginine Nutrition 0.000 description 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- 229920000954 Polyglycolide Polymers 0.000 description 1
- 230000032900 absorption of visible light Effects 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000000862 absorption spectrum Methods 0.000 description 1
- 229960000583 acetic acid Drugs 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 206010061592 cardiac fibrillation Diseases 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 229920005565 cyclic polymer Polymers 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000013583 drug formulation Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 230000002600 fibrillogenic effect Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000012362 glacial acetic acid Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 238000010829 isocratic elution Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 description 1
- 230000010494 opalescence Effects 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
- 238000011197 physicochemical method Methods 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000004633 polyglycolic acid Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
- 238000004383 yellowing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/06—Ampoules or carpules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/06—Ampoules or carpules
- A61J1/062—Carpules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L23/04—Homopolymers or copolymers of ethene
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L23/10—Homopolymers or copolymers of propene
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L23/10—Homopolymers or copolymers of propene
- C08L23/12—Polypropene
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
- Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
- Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
- Y10T428/1397—Single layer [continuous layer]
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Packging For Living Organisms, Food Or Medicinal Products That Are Sensitive To Environmental Conditiond (AREA)
- Packages (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK149896 | 1996-12-23 | ||
| PCT/DK1997/000570 WO1998027926A1 (en) | 1996-12-23 | 1997-12-16 | A medicament container of polymer of linear olefin for storing a liquid medicament |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO993084D0 NO993084D0 (no) | 1999-06-22 |
| NO993084L NO993084L (no) | 1999-08-20 |
| NO314123B1 true NO314123B1 (no) | 2003-02-03 |
Family
ID=8105469
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19993083A NO314122B1 (no) | 1996-12-23 | 1999-06-22 | Medikamentbeholder av syklisk hydrokarbon-polymer for lagring av flytende medikament, og anvendelse av medikamentbeholderen |
| NO19993084A NO314123B1 (no) | 1996-12-23 | 1999-06-22 | Medikamentbeholder av line¶r olefin-polymer for lagring av flytende medikament, og anvendelse av medikamentbeholderen |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19993083A NO314122B1 (no) | 1996-12-23 | 1999-06-22 | Medikamentbeholder av syklisk hydrokarbon-polymer for lagring av flytende medikament, og anvendelse av medikamentbeholderen |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US5945187A (ko) |
| EP (2) | EP0954273A1 (ko) |
| JP (2) | JP2001506887A (ko) |
| KR (2) | KR20000069680A (ko) |
| CN (2) | CN1244109A (ko) |
| AT (1) | ATE215348T1 (ko) |
| AU (3) | AU728503B2 (ko) |
| BR (2) | BR9714078A (ko) |
| CA (2) | CA2275894A1 (ko) |
| CZ (2) | CZ221199A3 (ko) |
| DE (1) | DE69711703T3 (ko) |
| DK (1) | DK0954272T3 (ko) |
| ES (1) | ES2174314T3 (ko) |
| HU (2) | HUP0000081A3 (ko) |
| IL (2) | IL130432A0 (ko) |
| IN (1) | IN186895B (ko) |
| NO (2) | NO314122B1 (ko) |
| PL (2) | PL334251A1 (ko) |
| PT (1) | PT954272E (ko) |
| RU (2) | RU2183110C2 (ko) |
| WO (2) | WO1998027926A1 (ko) |
| ZA (2) | ZA9711380B (ko) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030166525A1 (en) * | 1998-07-23 | 2003-09-04 | Hoffmann James Arthur | FSH Formulation |
| DE60038386T2 (de) * | 1999-09-08 | 2009-04-23 | Chugai Seiyaku K.K. | Stabile proteinlösung abgefüllt in einem behältnis aus hydrophobem harz und eine methode zur stabilisierung derselben |
| US6590033B2 (en) | 1999-09-09 | 2003-07-08 | Baxter International Inc. | Cycloolefin blends and method for solvent bonding polyolefins |
| US6632318B1 (en) | 1999-09-09 | 2003-10-14 | Baxter International Inc. | Method for solvent bonding polyolefins |
| US6613187B1 (en) | 1999-09-09 | 2003-09-02 | Baxter International Inc | Solvent bonding method for polyolefin materials |
| US6297322B1 (en) | 1999-09-09 | 2001-10-02 | Baxter International Inc. | Cycloolefin blends and method for solvent bonding polyolefins |
| US6255396B1 (en) | 1999-09-09 | 2001-07-03 | Baxter International Inc. | Cycloolefin blends and method for solvent bonding polyolefins |
| US6497676B1 (en) | 2000-02-10 | 2002-12-24 | Baxter International | Method and apparatus for monitoring and controlling peritoneal dialysis therapy |
| US6723399B2 (en) | 2002-06-12 | 2004-04-20 | Ferro Corporation | Medical multilayer film structure |
| US7238164B2 (en) | 2002-07-19 | 2007-07-03 | Baxter International Inc. | Systems, methods and apparatuses for pumping cassette-based therapies |
| EP1581447A1 (en) * | 2002-11-14 | 2005-10-05 | Ramsey Products Corporation | End protector link for conveyor chain |
| AR043972A1 (es) * | 2003-04-02 | 2005-08-17 | Ares Trading Sa | Formulaciones farmaceuticas de fsh y lh |
| PT1638595E (pt) * | 2003-06-20 | 2013-04-26 | Ares Trading Sa | Fsh liofilizada / formulações de hl |
| CA2529023A1 (en) * | 2003-06-27 | 2005-01-06 | Novo Nordisk A/S | High moisture barrier container for medical liquid compositions |
| EP1699629B1 (en) * | 2003-12-22 | 2010-10-06 | Novo Nordisk A/S | Transparent, flexible , impermeable plastic container for storage of pharmaceutical liquids |
| JP2005212745A (ja) * | 2004-02-02 | 2005-08-11 | Toyota Motor Corp | レーダ装置ビーム経路内用成形品 |
| US7802675B2 (en) * | 2005-05-13 | 2010-09-28 | Ramsey Products Corporation | End protector link for conveyor chain |
| EP1738896A1 (en) * | 2005-06-28 | 2007-01-03 | Novo Nordisk A/S | Multilayer film with septum layer |
| DE202006001454U1 (de) | 2005-08-04 | 2006-04-20 | Polysack Plastic Industries Ltd. | Polymere Folien mit geringem Gehalt an zyklischen olefinischen Polymeren und andere polymere Folien mit geringer Dichte |
| JP2009522032A (ja) * | 2006-01-06 | 2009-06-11 | ノボ・ノルデイスク・エー／エス | 圧潰可能なリザーバを利用する薬物送達装置 |
| EP2096996A2 (en) * | 2006-11-14 | 2009-09-09 | Novo Nordisk A/S | Adaptive hypoglycaemia alert system and method |
| US8870812B2 (en) | 2007-02-15 | 2014-10-28 | Baxter International Inc. | Dialysis system having video display with ambient light adjustment |
| US8206353B2 (en) * | 2008-04-11 | 2012-06-26 | Medtronic Minimed, Inc. | Reservoir barrier layer systems and methods |
| US9295776B2 (en) | 2008-04-11 | 2016-03-29 | Medtronic Minimed, Inc. | Reservoir plunger head systems and methods |
| US8858501B2 (en) * | 2008-04-11 | 2014-10-14 | Medtronic Minimed, Inc. | Reservoir barrier layer systems and methods |
| CN102090118B (zh) * | 2008-07-07 | 2013-11-06 | 住友电气工业株式会社 | 基站装置 |
| EP2251453B1 (en) | 2009-05-13 | 2013-12-11 | SiO2 Medical Products, Inc. | Vessel holder |
| US9458536B2 (en) | 2009-07-02 | 2016-10-04 | Sio2 Medical Products, Inc. | PECVD coating methods for capped syringes, cartridges and other articles |
| US20110152820A1 (en) * | 2009-12-22 | 2011-06-23 | Medtronic Minimed, Inc. | Barrier coatings for fluids contacting medical devices |
| US11624115B2 (en) | 2010-05-12 | 2023-04-11 | Sio2 Medical Products, Inc. | Syringe with PECVD lubrication |
| EP2585295B1 (en) | 2010-06-22 | 2016-03-23 | Novo Nordisk A/S | Medical container protected against cracking |
| US9878101B2 (en) | 2010-11-12 | 2018-01-30 | Sio2 Medical Products, Inc. | Cyclic olefin polymer vessels and vessel coating methods |
| US8474607B2 (en) | 2010-11-19 | 2013-07-02 | Ramsey Products Corporation | Integrated multi-functional links for chain link conveyor and method |
| US9272095B2 (en) | 2011-04-01 | 2016-03-01 | Sio2 Medical Products, Inc. | Vessels, contact surfaces, and coating and inspection apparatus and methods |
| WO2012137945A1 (ja) * | 2011-04-06 | 2012-10-11 | 株式会社大塚製薬工場 | プラスチックアンプル |
| EP2556815A1 (en) | 2011-08-10 | 2013-02-13 | Debiotech S.A. | Container for storing a drug such as insulin |
| US11116695B2 (en) | 2011-11-11 | 2021-09-14 | Sio2 Medical Products, Inc. | Blood sample collection tube |
| CN103930595A (zh) | 2011-11-11 | 2014-07-16 | Sio2医药产品公司 | 用于药物包装的钝化、pH保护性或润滑性涂层、涂布方法以及设备 |
| US9068565B2 (en) * | 2012-05-03 | 2015-06-30 | Becton, Dickinson And Company | Container and method for storing a pharmaceutical agent |
| EP2846755A1 (en) | 2012-05-09 | 2015-03-18 | SiO2 Medical Products, Inc. | Saccharide protective coating for pharmaceutical package |
| WO2014071061A1 (en) | 2012-11-01 | 2014-05-08 | Sio2 Medical Products, Inc. | Coating inspection method |
| US9903782B2 (en) | 2012-11-16 | 2018-02-27 | Sio2 Medical Products, Inc. | Method and apparatus for detecting rapid barrier coating integrity characteristics |
| AU2013352436B2 (en) | 2012-11-30 | 2018-10-25 | Sio2 Medical Products, Inc. | Controlling the uniformity of PECVD deposition on medical syringes, cartridges, and the like |
| US9764093B2 (en) | 2012-11-30 | 2017-09-19 | Sio2 Medical Products, Inc. | Controlling the uniformity of PECVD deposition |
| BR112015013198B1 (pt) | 2012-12-07 | 2021-03-30 | Bemis Company, Inc | Película multicamadas e embalagem tipo blister termoformada obtida a partir de dita película |
| EP2961858B1 (en) | 2013-03-01 | 2022-09-07 | Si02 Medical Products, Inc. | Coated syringe. |
| US9937099B2 (en) | 2013-03-11 | 2018-04-10 | Sio2 Medical Products, Inc. | Trilayer coated pharmaceutical packaging with low oxygen transmission rate |
| US20160015600A1 (en) | 2013-03-11 | 2016-01-21 | Sio2 Medical Products, Inc. | Coated packaging |
| WO2014144926A1 (en) | 2013-03-15 | 2014-09-18 | Sio2 Medical Products, Inc. | Coating method |
| US20150225151A1 (en) * | 2014-02-11 | 2015-08-13 | Christopher L. Osborn | Anti-Scalping Transdermal Patch Packaging Film |
| EP3693493A1 (en) | 2014-03-28 | 2020-08-12 | SiO2 Medical Products, Inc. | Antistatic coatings for plastic vessels |
| US11077233B2 (en) | 2015-08-18 | 2021-08-03 | Sio2 Medical Products, Inc. | Pharmaceutical and other packaging with low oxygen transmission rate |
| WO2017163773A1 (ja) | 2016-03-24 | 2017-09-28 | テルモ株式会社 | 薬剤容器 |
| DE202016007973U1 (de) | 2016-12-22 | 2017-01-18 | Topas Advanced Polymers Gmbh | Behälter enthaltend Cycloolefincopolymer-Elastomere und deren Verwendung |
| US11179516B2 (en) | 2017-06-22 | 2021-11-23 | Baxter International Inc. | Systems and methods for incorporating patient pressure into medical fluid delivery |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58112546A (ja) * | 1981-12-26 | 1983-07-05 | テルモ株式会社 | 医療用容器 |
| ATE234882T1 (de) | 1987-05-01 | 2003-04-15 | Mitsui Chemicals Inc | Ungeordnete cycloolefincopolymerzusammensetzungen und deren anwendung |
| EP0524802B2 (en) | 1991-07-22 | 2009-10-07 | Daikyo Gomu Seiko Ltd. | A container for a sanitary article |
| JP2914826B2 (ja) * | 1991-07-22 | 1999-07-05 | 株式会社大協精工 | 衛生品用容器 |
| DK0556034T4 (da) † | 1992-02-12 | 2004-11-15 | Daikyo Gomu Seiko Kk | Et medicinsk instrument |
| EP0564206A2 (en) * | 1992-03-30 | 1993-10-06 | Terumo Kabushiki Kaisha | Medical container |
| CA2120315C (en) * | 1993-04-30 | 2001-05-15 | Joel L. Williams | Medical articles and process therefor |
| JP3384054B2 (ja) * | 1993-08-25 | 2003-03-10 | ジェイエスアール株式会社 | 熱可塑性ノルボルネンポリマー |
| CA2134320C (en) * | 1993-10-26 | 2001-01-09 | Toshiyuki Hirose | Polyolefin multilayer laminate and use thereof |
| JP3973703B2 (ja) * | 1994-11-07 | 2007-09-12 | テルモ株式会社 | 医療用複室容器 |
| JPH08155007A (ja) * | 1994-12-02 | 1996-06-18 | Mitsui Petrochem Ind Ltd | 薬剤充填容器製剤及びこれに用いる容器 |
| US5582957A (en) * | 1995-03-28 | 1996-12-10 | Eastman Kodak Company | Resuspension optimization for photographic nanosuspensions |
| JP3661234B2 (ja) * | 1995-08-11 | 2005-06-15 | 東洋製罐株式会社 | 内容物による着色を防止する方法 |
| JPH0999037A (ja) * | 1995-10-05 | 1997-04-15 | Terumo Corp | 医療用複室容器 |
| JPH0999036A (ja) * | 1995-10-05 | 1997-04-15 | Terumo Corp | 医療用容器 |
| JP3529945B2 (ja) * | 1996-07-09 | 2004-05-24 | 三井化学株式会社 | ポリエチレン製医療用ボトル |
-
1997
- 1997-12-16 CN CN97181308A patent/CN1244109A/zh active Pending
- 1997-12-16 AU AU53099/98A patent/AU728503B2/en not_active Ceased
- 1997-12-16 RU RU99116251/14A patent/RU2183110C2/ru not_active IP Right Cessation
- 1997-12-16 DE DE69711703T patent/DE69711703T3/de not_active Expired - Lifetime
- 1997-12-16 US US08/991,518 patent/US5945187A/en not_active Expired - Lifetime
- 1997-12-16 KR KR1019997005727A patent/KR20000069680A/ko not_active Application Discontinuation
- 1997-12-16 IL IL13043297A patent/IL130432A0/xx unknown
- 1997-12-16 CZ CZ992211A patent/CZ221199A3/cs unknown
- 1997-12-16 IL IL13043397A patent/IL130433A0/xx unknown
- 1997-12-16 PL PL97334251A patent/PL334251A1/xx unknown
- 1997-12-16 WO PCT/DK1997/000570 patent/WO1998027926A1/en not_active Application Discontinuation
- 1997-12-16 AU AU53100/98A patent/AU741689B2/en not_active Ceased
- 1997-12-16 CA CA002275894A patent/CA2275894A1/en not_active Abandoned
- 1997-12-16 BR BR9714078-3A patent/BR9714078A/pt not_active Application Discontinuation
- 1997-12-16 PT PT97949988T patent/PT954272E/pt unknown
- 1997-12-16 BR BR9713627-1A patent/BR9713627A/pt active Search and Examination
- 1997-12-16 EP EP97949989A patent/EP0954273A1/en not_active Withdrawn
- 1997-12-16 PL PL97334252A patent/PL334252A1/xx unknown
- 1997-12-16 WO PCT/DK1997/000569 patent/WO1998027925A1/en not_active Application Discontinuation
- 1997-12-16 AT AT97949988T patent/ATE215348T1/de not_active IP Right Cessation
- 1997-12-16 DK DK97949988T patent/DK0954272T3/da active
- 1997-12-16 EP EP97949988A patent/EP0954272B2/en not_active Expired - Lifetime
- 1997-12-16 JP JP52825398A patent/JP2001506887A/ja active Pending
- 1997-12-16 HU HU0000081A patent/HUP0000081A3/hu unknown
- 1997-12-16 CZ CZ992212A patent/CZ221299A3/cs unknown
- 1997-12-16 JP JP52825498A patent/JP4672818B2/ja not_active Expired - Fee Related
- 1997-12-16 ES ES97949988T patent/ES2174314T3/es not_active Expired - Lifetime
- 1997-12-16 CN CN97181309A patent/CN1244110A/zh active Pending
- 1997-12-16 CA CA002275903A patent/CA2275903A1/en not_active Abandoned
- 1997-12-16 AU AU5309998D patent/AU719221B2/xx not_active Expired - Lifetime
- 1997-12-16 US US08/991,519 patent/US6680091B2/en not_active Expired - Lifetime
- 1997-12-16 KR KR1019997005728A patent/KR20000069681A/ko not_active Application Discontinuation
- 1997-12-16 HU HU9904598A patent/HUP9904598A3/hu unknown
- 1997-12-16 RU RU99116323/14A patent/RU2183111C2/ru not_active IP Right Cessation
- 1997-12-18 ZA ZA9711380A patent/ZA9711380B/xx unknown
- 1997-12-18 ZA ZA9711387A patent/ZA9711387B/xx unknown
- 1997-12-23 IN IN3755DE1997 patent/IN186895B/en unknown
-
1999
- 1999-06-22 NO NO19993083A patent/NO314122B1/no unknown
- 1999-06-22 NO NO19993084A patent/NO314123B1/no unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO314123B1 (no) | Medikamentbeholder av line¶r olefin-polymer for lagring av flytende medikament, og anvendelse av medikamentbeholderen | |
| EP2990031B1 (en) | Parenteral dosage form of norepinephrine | |
| CN104254319A (zh) | 即可灌注的吉西他滨溶液 | |
| US11738011B2 (en) | Ready-to-administer fentanyl formulations | |
| US20230329971A1 (en) | Medicinal product comprising a flexible plastic bag and an aqueous, ready-to-use solution of midazolam | |
| US20230390156A1 (en) | Pharmaceutical packages comprising polypropylene containers and ngf aqueous formulations packaged therein | |
| MXPA99005887A (en) | A medicament container of polymer of linear olefin for storing a liquid medicament | |
| US10888534B2 (en) | Storage stable ready-to-use norepinephrine aqueous solutions in flexible plastic bags | |
| MXPA99005881A (en) | A medicament container of polymer of cyclic hydrocarbon for storing a liquid medicament | |
| NO327263B1 (no) | Parenterale formuleringer som inneholder 10-hydroksy-10,11-tetrahydrokarbamazepin, enhetsdoseringsform og beholder inneholdende nevnte parenterale formulering, samt anvendelse av nevnte parenterale formulering. | |
| JP2006212148A (ja) | 薬剤包装用基材、薬剤包装用容器およびこれらを使用した製剤 | |
| JP2024517732A (ja) | 低密度ポリエチレンのコンテナに含まれるデクスメデトミジンの溶液 | |
| Matsui et al. | Stability of Doxorubicin and Vincristine in Various Infusion Solutions for VAD Therapy |