NO305796B1 - Pyrrolidenmetylderivater, farmas°ytiske preparater inneholdende slike, deres anvendelse til fremstilling av terapeutika samt mellomprodukt - Google Patents
Pyrrolidenmetylderivater, farmas°ytiske preparater inneholdende slike, deres anvendelse til fremstilling av terapeutika samt mellomproduktInfo
- Publication number
- NO305796B1 NO305796B1 NO953280A NO953280A NO305796B1 NO 305796 B1 NO305796 B1 NO 305796B1 NO 953280 A NO953280 A NO 953280A NO 953280 A NO953280 A NO 953280A NO 305796 B1 NO305796 B1 NO 305796B1
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- alkoxy
- alkenyl
- substituted
- unsubstituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939326284A GB9326284D0 (en) | 1993-12-23 | 1993-12-23 | Pyrrolydenemethyl-derivatives and process for their preparation |
| PCT/EP1994/004006 WO1995017381A1 (fr) | 1993-12-23 | 1994-12-02 | Nouveaux derives 2,2'-bi-1h-pyrrole possedant une activite immunosuppressive |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO953280D0 NO953280D0 (no) | 1995-08-21 |
| NO953280L NO953280L (no) | 1995-08-21 |
| NO305796B1 true NO305796B1 (no) | 1999-07-26 |
Family
ID=10747089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO953280A NO305796B1 (no) | 1993-12-23 | 1995-08-21 | Pyrrolidenmetylderivater, farmas°ytiske preparater inneholdende slike, deres anvendelse til fremstilling av terapeutika samt mellomprodukt |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5691334A (fr) |
| EP (2) | EP0686147B1 (fr) |
| JP (1) | JP3594311B2 (fr) |
| KR (1) | KR100365057B1 (fr) |
| CN (1) | CN1120153C (fr) |
| AT (1) | ATE224874T1 (fr) |
| AU (1) | AU689169B2 (fr) |
| CA (1) | CA2155096A1 (fr) |
| DE (1) | DE69431429T2 (fr) |
| DK (1) | DK0686147T3 (fr) |
| ES (1) | ES2184786T3 (fr) |
| FI (1) | FI109688B (fr) |
| GB (1) | GB9326284D0 (fr) |
| HU (1) | HUT73663A (fr) |
| IL (1) | IL112022A (fr) |
| MY (1) | MY113304A (fr) |
| NO (1) | NO305796B1 (fr) |
| NZ (1) | NZ276716A (fr) |
| PL (1) | PL183112B1 (fr) |
| PT (1) | PT686147E (fr) |
| RU (1) | RU2145957C1 (fr) |
| TW (1) | TW285670B (fr) |
| UA (1) | UA57697C2 (fr) |
| WO (1) | WO1995017381A1 (fr) |
| ZA (1) | ZA9410203B (fr) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2736550B1 (fr) * | 1995-07-14 | 1998-07-24 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule |
| GB9603212D0 (en) * | 1996-02-15 | 1996-04-17 | Pharmacia Spa | Process for the preparation of 2,2'-bipyrrolyl-pyrromethane derivatives |
| GB9619706D0 (en) * | 1996-09-20 | 1996-11-06 | Pharmacia Spa | Synergistic immunosuppressant composition containing a 2,2'-bi-1H-pyrrole comp und |
| GB9705035D0 (en) * | 1997-03-11 | 1997-04-30 | Pharmacia & Upjohn Spa | Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation |
| US5989591A (en) * | 1997-03-14 | 1999-11-23 | American Home Products Corporation | Rapamycin formulations for oral administration |
| KR100252197B1 (ko) * | 1997-09-20 | 2000-04-15 | 박호군 | 세라시아 마르세센스 균주의 배양액으로 부터 분리한 면역억제제용 프로디지오신 |
| GB9802745D0 (en) * | 1998-02-09 | 1998-04-08 | Pharmacia & Upjohn Spa | Benzyloxy prodigiosine compounds |
| US20040014987A1 (en) * | 2000-01-26 | 2004-01-22 | Gemin X Biotechnologies Inc. | Pyrrole-Type compounds, compositions, and methods for treating cancer or viral diseases |
| US6407244B1 (en) | 2000-01-26 | 2002-06-18 | Gemin X Biotechnologies Inc. | Pyrrole-type compounds, compositions, and methods for treating cancer or viral diseases |
| KR20010081515A (ko) * | 2000-02-15 | 2001-08-29 | 복성해 | 프로디지오신의 당뇨병 예방 및 치료용 조성물 |
| KR100392225B1 (ko) * | 2001-04-19 | 2003-07-22 | 한국생명공학연구원 | 류머티스 관절염 치료용 프로디지오신 조성물 |
| ES2304135T3 (es) | 2001-07-18 | 2008-09-16 | Gemin X Biotechnologies Inc. | Compuestos tipo pirrol, composiciones y metodos para tratar el cancer, tratar enfermedades virales y causar inmunosupresion. |
| DK1644363T3 (da) | 2003-05-30 | 2012-05-29 | Gemin X Pharmaceuticals Canada Inc | Triheterocykliske forbindelser, sammensætninger og fremgangsmåder til behandling af cancer eller virussygdomme |
| CA2571710A1 (fr) | 2004-06-24 | 2006-11-02 | Nicholas Valiante | Immuno-potentialisateurs a petites molecules et analyses visant a detecter leur presence |
| EP1853255A4 (fr) * | 2005-02-22 | 2009-07-08 | Gemin X Pharmaceuticals Canada | Procédés pour traiter l arthrite à l aide de composés trihétérocycliques |
| KR100674222B1 (ko) * | 2005-07-11 | 2007-01-24 | 한국생명공학연구원 | 세라시아 마르세센스 ｂ-1231 ｋｃｔｃ 0386ｂｐ로부터분리한 프로디지오신을 유효성분으로 포함한 급성이식편대숙주병의 예방 및 치료용 조성물 |
| CA2636324C (fr) | 2006-01-06 | 2012-03-20 | Sepracor Inc. | Cycloalkylamines inhibiteurs du recaptage des monoamines |
| KR101381768B1 (ko) | 2006-01-06 | 2014-04-07 | 선오비온 파마슈티컬스 인코포레이티드 | 테트랄론-기재 모노아민 재흡수 저해제 |
| ES2643602T3 (es) | 2006-03-31 | 2017-11-23 | Sunovion Pharmaceuticals Inc. | Aminas y quirales |
| US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| US20080051400A1 (en) * | 2006-07-06 | 2008-02-28 | Gemin X Biotechnologies Inc. | Methods for treating or preventing anemia or thrombocytopenia using a triheterocyclic compound |
| US7902252B2 (en) | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
| CN103936605B (zh) | 2007-05-31 | 2017-09-01 | 赛诺维信制药公司 | 苯基取代的环烷胺作为一元胺再摄取抑制剂 |
| CN103387529B (zh) * | 2013-07-30 | 2016-03-30 | 中国农业科学院烟草研究所 | 抗tmv的三吡咯环类化合物及其制备方法和用途 |
| ES2615077B1 (es) * | 2015-12-02 | 2018-03-14 | Universidad De Burgos | Una nueva familia de compuestos, procedimiento de obtención de los mismos y sus usos en el tratamiento y/o profilaxis de enfermedades |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61280429A (ja) * | 1985-06-06 | 1986-12-11 | Chugai Pharmaceut Co Ltd | 免疫抑制剤 |
| SU1409276A1 (ru) * | 1985-11-10 | 1988-07-15 | Донецкий медицинский институт им.М.Горького | Способ лечени острых кишечных инфекций |
| JPH02250828A (ja) * | 1989-03-23 | 1990-10-08 | Nippon Kayaku Co Ltd | 新規免疫抑制剤 |
-
1993
- 1993-12-23 GB GB939326284A patent/GB9326284D0/en active Pending
-
1994
- 1994-02-12 UA UA95094273A patent/UA57697C2/uk unknown
- 1994-12-02 ES ES95902113T patent/ES2184786T3/es not_active Expired - Lifetime
- 1994-12-02 AU AU11090/95A patent/AU689169B2/en not_active Ceased
- 1994-12-02 PL PL94310387A patent/PL183112B1/pl not_active IP Right Cessation
- 1994-12-02 WO PCT/EP1994/004006 patent/WO1995017381A1/fr active IP Right Grant
- 1994-12-02 JP JP51712595A patent/JP3594311B2/ja not_active Expired - Fee Related
- 1994-12-02 CN CN94191273A patent/CN1120153C/zh not_active Expired - Fee Related
- 1994-12-02 RU RU95120169A patent/RU2145957C1/ru not_active IP Right Cessation
- 1994-12-02 DK DK95902113T patent/DK0686147T3/da active
- 1994-12-02 DE DE69431429T patent/DE69431429T2/de not_active Expired - Fee Related
- 1994-12-02 CA CA002155096A patent/CA2155096A1/fr not_active Abandoned
- 1994-12-02 KR KR1019950703548A patent/KR100365057B1/ko not_active IP Right Cessation
- 1994-12-02 HU HU9502782A patent/HUT73663A/hu unknown
- 1994-12-02 AT AT95902113T patent/ATE224874T1/de not_active IP Right Cessation
- 1994-12-02 NZ NZ276716A patent/NZ276716A/en unknown
- 1994-12-02 US US08/505,292 patent/US5691334A/en not_active Expired - Fee Related
- 1994-12-02 EP EP95902113A patent/EP0686147B1/fr not_active Expired - Lifetime
- 1994-12-02 EP EP02077192A patent/EP1241162A1/fr not_active Withdrawn
- 1994-12-02 PT PT95902113T patent/PT686147E/pt unknown
- 1994-12-19 TW TW083111857A patent/TW285670B/zh active
- 1994-12-19 IL IL11202294A patent/IL112022A/en not_active IP Right Cessation
- 1994-12-21 ZA ZA9410203A patent/ZA9410203B/xx unknown
- 1994-12-22 MY MYPI94003486A patent/MY113304A/en unknown
-
1995
- 1995-08-21 NO NO953280A patent/NO305796B1/no unknown
- 1995-08-21 FI FI953919A patent/FI109688B/fi not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO305796B1 (no) | Pyrrolidenmetylderivater, farmas°ytiske preparater inneholdende slike, deres anvendelse til fremstilling av terapeutika samt mellomprodukt | |
| HK1026700A1 (en) | 1,4-Substituted cyclic amine derivatives or dihydroindole derivatives and medicament thereof. | |
| AU1163492A (en) | 3-benzylidene-1-carbamoyl-2-pyrrolidone analog | |
| HUP0001154A2 (hu) | 3-Piperidil-4-oxo-kinazolin-származékok és a vegyületeket tartalmazó gyógyászati készítmények | |
| FI931763A (fi) | 4,1-bensoxazepinderivat och deras anvaendning | |
| DK0565377T3 (da) | Terapeutiske midler til behandling af Parkinsons sygdom | |
| US5021413B1 (en) | Analgesic thiomorpholins, their preparation, and pharmaceutical compositions containing them | |
| MX9707768A (es) | Proceso para preparacion de derivados de 2,2'-bipirrolil- pirrometeno (prodigiosinas). | |
| AU6158486A (en) | Dihydro pyridine derivatives | |
| FR2702477B1 (fr) | Dérivés de benzoxazine, leur préparation et leur application en thérapeutique. | |
| MY131762A (en) | Pharmaceutical compounds | |
| ATE102199T1 (de) | 4-amino-3-carboxynaphthyridin-derivate, ihre herstellung und pharmazeutische zusammensetzungen. | |
| DK1155012T3 (da) | Dihydroquinazolinderivater med anti-cancer-aktivitet | |
| WO1999029309A3 (fr) | Derives de 2,2'-bi-1h-pyrrole utilises pour traiter la leucemie provoquee par le virus htlv-1 | |
| MX9803920A (es) | Composicion sinergica inmunosupresora que contiene un compuesto de 2,2'-bi-1h-pirrol. | |
| TW360642B (en) | 1,4-Benzoxazine derivatives | |
| DE68912055D1 (de) | Aryloxy-, Arylthio-, Heteroaryloxy-, Heteroarylthio-Alkenylen-Derivate von Aminen. | |
| FR2694557B1 (fr) | Dérivés de tétrahydronaphtalène, leur préparation, et leur application en thérapeutique. |