IL112022A - History of pyrolidenemethyl, their preparation and pharmaceutical preparations containing them - Google Patents
History of pyrolidenemethyl, their preparation and pharmaceutical preparations containing themInfo
- Publication number
- IL112022A IL112022A IL11202294A IL11202294A IL112022A IL 112022 A IL112022 A IL 112022A IL 11202294 A IL11202294 A IL 11202294A IL 11202294 A IL11202294 A IL 11202294A IL 112022 A IL112022 A IL 112022A
- Authority
- IL
- Israel
- Prior art keywords
- methyl
- pyrrole
- pyrrol
- ylidene
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939326284A GB9326284D0 (en) | 1993-12-23 | 1993-12-23 | Pyrrolydenemethyl-derivatives and process for their preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL112022A0 IL112022A0 (en) | 1995-03-15 |
| IL112022A true IL112022A (en) | 1998-12-27 |
Family
ID=10747089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11202294A IL112022A (en) | 1993-12-23 | 1994-12-19 | History of pyrolidenemethyl, their preparation and pharmaceutical preparations containing them |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5691334A (fr) |
| EP (2) | EP1241162A1 (fr) |
| JP (1) | JP3594311B2 (fr) |
| KR (1) | KR100365057B1 (fr) |
| CN (1) | CN1120153C (fr) |
| AT (1) | ATE224874T1 (fr) |
| AU (1) | AU689169B2 (fr) |
| CA (1) | CA2155096A1 (fr) |
| DE (1) | DE69431429T2 (fr) |
| DK (1) | DK0686147T3 (fr) |
| ES (1) | ES2184786T3 (fr) |
| FI (1) | FI109688B (fr) |
| GB (1) | GB9326284D0 (fr) |
| HU (1) | HUT73663A (fr) |
| IL (1) | IL112022A (fr) |
| MY (1) | MY113304A (fr) |
| NO (1) | NO305796B1 (fr) |
| NZ (1) | NZ276716A (fr) |
| PL (1) | PL183112B1 (fr) |
| PT (1) | PT686147E (fr) |
| RU (1) | RU2145957C1 (fr) |
| TW (1) | TW285670B (fr) |
| UA (1) | UA57697C2 (fr) |
| WO (1) | WO1995017381A1 (fr) |
| ZA (1) | ZA9410203B (fr) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2736550B1 (fr) * | 1995-07-14 | 1998-07-24 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule |
| GB9603212D0 (en) * | 1996-02-15 | 1996-04-17 | Pharmacia Spa | Process for the preparation of 2,2'-bipyrrolyl-pyrromethane derivatives |
| GB9619706D0 (en) * | 1996-09-20 | 1996-11-06 | Pharmacia Spa | Synergistic immunosuppressant composition containing a 2,2'-bi-1H-pyrrole comp und |
| GB9705035D0 (en) * | 1997-03-11 | 1997-04-30 | Pharmacia & Upjohn Spa | Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation |
| US5989591A (en) * | 1997-03-14 | 1999-11-23 | American Home Products Corporation | Rapamycin formulations for oral administration |
| KR100252197B1 (ko) * | 1997-09-20 | 2000-04-15 | 박호군 | 세라시아 마르세센스 균주의 배양액으로 부터 분리한 면역억제제용 프로디지오신 |
| GB9802745D0 (en) | 1998-02-09 | 1998-04-08 | Pharmacia & Upjohn Spa | Benzyloxy prodigiosine compounds |
| US20040014987A1 (en) * | 2000-01-26 | 2004-01-22 | Gemin X Biotechnologies Inc. | Pyrrole-Type compounds, compositions, and methods for treating cancer or viral diseases |
| US6407244B1 (en) | 2000-01-26 | 2002-06-18 | Gemin X Biotechnologies Inc. | Pyrrole-type compounds, compositions, and methods for treating cancer or viral diseases |
| KR20010081515A (ko) * | 2000-02-15 | 2001-08-29 | 복성해 | 프로디지오신의 당뇨병 예방 및 치료용 조성물 |
| KR100392225B1 (ko) * | 2001-04-19 | 2003-07-22 | 한국생명공학연구원 | 류머티스 관절염 치료용 프로디지오신 조성물 |
| DE60223571T2 (de) * | 2001-07-18 | 2008-07-24 | Gemin X Pharmaceuticals Canada. Inc., Montreal | Verbindungen vom pyrroltyp, zusammensetzungen und verfahren zur behandlung von krebs, zur behandlung von virenerkrankungen und zur unterdrückung der immunreaktion |
| ES2382377T3 (es) | 2003-05-30 | 2012-06-07 | Gemin X Pharmaceuticals Canada Inc. | Compuestos triheterocíclicos, composiciones, y métodos para tratar cáncer |
| CA2571710A1 (fr) | 2004-06-24 | 2006-11-02 | Nicholas Valiante | Immuno-potentialisateurs a petites molecules et analyses visant a detecter leur presence |
| WO2006089397A1 (fr) * | 2005-02-22 | 2006-08-31 | Gemin X Biotechnologies Inc. | Procédés pour traiter l’arthrite à l’aide de composés trihétérocycliques |
| KR100674222B1 (ko) * | 2005-07-11 | 2007-01-24 | 한국생명공학연구원 | 세라시아 마르세센스 ｂ-1231 ｋｃｔｃ 0386ｂｐ로부터분리한 프로디지오신을 유효성분으로 포함한 급성이식편대숙주병의 예방 및 치료용 조성물 |
| AU2006335174B2 (en) | 2006-01-06 | 2012-09-06 | Sunovion Pharmaceuticals Inc. | Tetralone-based monoamine reuptake inhibitors |
| CN101394847B (zh) | 2006-01-06 | 2017-05-24 | 塞普拉柯公司 | 作为单胺重摄取抑制剂的环烷基胺类 |
| CN103588659A (zh) | 2006-03-31 | 2014-02-19 | 赛诺维信制药公司 | 手性酰胺和胺的制备 |
| US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| US20080051400A1 (en) * | 2006-07-06 | 2008-02-28 | Gemin X Biotechnologies Inc. | Methods for treating or preventing anemia or thrombocytopenia using a triheterocyclic compound |
| US7902252B2 (en) | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
| EP2154962A4 (fr) | 2007-05-31 | 2012-08-15 | Sepracor Inc | Cycloalkylamines substitues par un phenyle en tant qu'inhibiteur du recaptage de monoamine |
| CN103387529B (zh) * | 2013-07-30 | 2016-03-30 | 中国农业科学院烟草研究所 | 抗tmv的三吡咯环类化合物及其制备方法和用途 |
| ES2615077B1 (es) * | 2015-12-02 | 2018-03-14 | Universidad De Burgos | Una nueva familia de compuestos, procedimiento de obtención de los mismos y sus usos en el tratamiento y/o profilaxis de enfermedades |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61280429A (ja) * | 1985-06-06 | 1986-12-11 | Chugai Pharmaceut Co Ltd | 免疫抑制剤 |
| SU1409276A1 (ru) * | 1985-11-10 | 1988-07-15 | Донецкий медицинский институт им.М.Горького | Способ лечени острых кишечных инфекций |
| JPH02250828A (ja) * | 1989-03-23 | 1990-10-08 | Nippon Kayaku Co Ltd | 新規免疫抑制剤 |
-
1993
- 1993-12-23 GB GB939326284A patent/GB9326284D0/en active Pending
-
1994
- 1994-02-12 UA UA95094273A patent/UA57697C2/uk unknown
- 1994-12-02 AT AT95902113T patent/ATE224874T1/de not_active IP Right Cessation
- 1994-12-02 PL PL94310387A patent/PL183112B1/pl not_active IP Right Cessation
- 1994-12-02 US US08/505,292 patent/US5691334A/en not_active Expired - Fee Related
- 1994-12-02 AU AU11090/95A patent/AU689169B2/en not_active Ceased
- 1994-12-02 EP EP02077192A patent/EP1241162A1/fr not_active Withdrawn
- 1994-12-02 CN CN94191273A patent/CN1120153C/zh not_active Expired - Fee Related
- 1994-12-02 PT PT95902113T patent/PT686147E/pt unknown
- 1994-12-02 RU RU95120169A patent/RU2145957C1/ru not_active IP Right Cessation
- 1994-12-02 CA CA002155096A patent/CA2155096A1/fr not_active Abandoned
- 1994-12-02 ES ES95902113T patent/ES2184786T3/es not_active Expired - Lifetime
- 1994-12-02 EP EP95902113A patent/EP0686147B1/fr not_active Expired - Lifetime
- 1994-12-02 NZ NZ276716A patent/NZ276716A/en unknown
- 1994-12-02 JP JP51712595A patent/JP3594311B2/ja not_active Expired - Fee Related
- 1994-12-02 WO PCT/EP1994/004006 patent/WO1995017381A1/fr active IP Right Grant
- 1994-12-02 KR KR1019950703548A patent/KR100365057B1/ko not_active IP Right Cessation
- 1994-12-02 DE DE69431429T patent/DE69431429T2/de not_active Expired - Fee Related
- 1994-12-02 HU HU9502782A patent/HUT73663A/hu unknown
- 1994-12-02 DK DK95902113T patent/DK0686147T3/da active
- 1994-12-19 IL IL11202294A patent/IL112022A/en not_active IP Right Cessation
- 1994-12-19 TW TW083111857A patent/TW285670B/zh active
- 1994-12-21 ZA ZA9410203A patent/ZA9410203B/xx unknown
- 1994-12-22 MY MYPI94003486A patent/MY113304A/en unknown
-
1995
- 1995-08-21 FI FI953919A patent/FI109688B/fi not_active IP Right Cessation
- 1995-08-21 NO NO953280A patent/NO305796B1/no unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |