NO20090175L - Stabile laquinimod sammensetninger - Google Patents
Stabile laquinimod sammensetningerInfo
- Publication number
- NO20090175L NO20090175L NO20090175A NO20090175A NO20090175L NO 20090175 L NO20090175 L NO 20090175L NO 20090175 A NO20090175 A NO 20090175A NO 20090175 A NO20090175 A NO 20090175A NO 20090175 L NO20090175 L NO 20090175L
- Authority
- NO
- Norway
- Prior art keywords
- compositions
- laquinimod
- stable
- stable laquinimod
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Abstract
Oppfinnelsen vedrører en farmasøytisk sammensetning som omfatter et farmasøytisk akseptabelt salt av N-etyl-N-fenyl-1,2-dihydro-4-hydroksy-5-klor-1-metyl-2-oksoquinolin-3-karboksamid, N-metylglukamin og en farmasøytisk akseptabel bærer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81324706P | 2006-06-12 | 2006-06-12 | |
PCT/US2007/013721 WO2007146248A2 (en) | 2006-06-12 | 2007-06-12 | Stable laquinimod preparations |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20090175L true NO20090175L (no) | 2009-03-11 |
NO342485B1 NO342485B1 (no) | 2018-05-28 |
Family
ID=38832466
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20090175A NO342485B1 (no) | 2006-06-12 | 2009-01-12 | Stabile laquinimod preparater |
Country Status (28)
Country | Link |
---|---|
US (3) | US7989473B2 (no) |
EP (1) | EP2035001B1 (no) |
JP (1) | JP5226678B2 (no) |
KR (4) | KR20160013273A (no) |
CN (1) | CN101466379B (no) |
AR (1) | AR061348A1 (no) |
AT (1) | ATE532515T1 (no) |
AU (1) | AU2007258366B2 (no) |
BR (1) | BRPI0713694A2 (no) |
CA (2) | CA2899472C (no) |
CY (1) | CY1113003T1 (no) |
DK (1) | DK2035001T3 (no) |
EA (1) | EA018031B1 (no) |
ES (1) | ES2377149T3 (no) |
HK (1) | HK1121971A1 (no) |
HR (1) | HRP20120093T1 (no) |
IL (1) | IL195724A (no) |
MX (1) | MX2008015808A (no) |
NO (1) | NO342485B1 (no) |
NZ (1) | NZ573846A (no) |
PL (1) | PL2035001T3 (no) |
PT (1) | PT2035001E (no) |
RS (1) | RS52169B (no) |
SI (1) | SI2035001T1 (no) |
TW (1) | TWI400073B (no) |
UA (1) | UA96449C2 (no) |
WO (1) | WO2007146248A2 (no) |
ZA (1) | ZA200810790B (no) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8314124B2 (en) | 2004-02-06 | 2012-11-20 | Active Biotech Ab | Crystalline salts of quinoline compounds and methods for preparing them |
UA92761C2 (ru) | 2005-10-19 | 2010-12-10 | Тева Фармасьютикл Индастриз, Лтд. | Кристаллы лаквинимода натрия и способ их изготовления |
AU2007258366B2 (en) | 2006-06-12 | 2012-10-25 | Active Biotech, Ab | Stable laquinimod preparations |
SI2234485T1 (sl) | 2007-12-20 | 2014-03-31 | Teva Pharmaceutical Industries Ltd. | Stabilni lakvinimodni pripravki |
EA021227B1 (ru) * | 2008-09-03 | 2015-05-29 | Тева Фармасьютикал Индастриз Лтд. | 2-оксо-1,2-дигидрохинолиновые модуляторы иммунной функции |
DE102009008851A1 (de) | 2009-02-13 | 2010-08-19 | Amw Gmbh | Transdermales System mit Immunmodulator |
DE102010048788A1 (de) | 2009-02-13 | 2011-05-19 | Amw Gmbh | Transdermales System mit Immunmodulator |
NZ597378A (en) * | 2009-06-19 | 2014-08-29 | Teva Pharma | Treatment of multiple sclerosis with laquinimod |
ES2564931T3 (es) * | 2009-07-30 | 2016-03-30 | Teva Pharmaceutical Industries Ltd. | Tratamiento de enfermedad de Crohn con laquinimod |
DK2467372T3 (en) * | 2009-08-10 | 2016-08-22 | Teva Pharma | TREATMENT OF BDNF-RELATED DISEASES USING LAQUINIMOD |
DE102010026879A1 (de) | 2010-02-11 | 2011-08-11 | AMW GmbH, 83627 | Transdermales System mit Immunmodulator |
PT2542079E (pt) * | 2010-03-03 | 2014-07-18 | Teva Pharma | Tratamento da artrite reumatoide com uma combinação de laquinimod e metotrexato |
PE20130613A1 (es) * | 2010-03-03 | 2013-06-23 | Teva Pharma | Tratamiento de lupus nefritis usando laquinimod |
SG183515A1 (en) * | 2010-03-03 | 2012-10-30 | Teva Pharma | Treatment of lupus arthritis using laquinimod |
US20120010239A1 (en) * | 2010-07-09 | 2012-01-12 | Ulf Tomas Fristedt | 5-chloro-4-hydroxy-1-methyl-2-oxo-n-phenyl-1,2-dihydroquinoline-3-carboxamide, salts and uses thereof |
KR20130092558A (ko) | 2010-07-09 | 2013-08-20 | 테바 파마슈티컬 인더스트리즈 리미티드 | 중수소화된 n-에틸-n-페닐-1,2-다이하이드로-4-하이드록시-5-클로로-1-메틸-2-옥소퀴놀린-3-카복스아마이드, 그의 염 및 용도 |
NZ611628A (en) * | 2010-12-07 | 2015-06-26 | Teva Pharma | Use of laquinimod for reducing fatigue, improving functional status, and improving quality of life in multiple sclerosis patients |
PE20142319A1 (es) * | 2011-07-28 | 2015-01-24 | Teva Pharma | Tratamiento de esclerosis multiple con combinacion de laquinimod y acetato de glatiramero |
SG10201606204TA (en) * | 2011-07-28 | 2016-09-29 | Teva Pharma | Treatment Of Multiple Sclerosis With Combination Of Laquinimod And Interferon-Beta |
US8889627B2 (en) * | 2011-10-12 | 2014-11-18 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
WO2013116657A1 (en) | 2012-02-03 | 2013-08-08 | Teva Pharmaceutical Industries Ltd. | USE OF LAQUINIMOD FOR TREATING CROHN'S DISEASE PATIENTS WHO FAILED FIRST-LINE ANTI-TNFα THERAPY |
US9284276B2 (en) | 2012-02-16 | 2016-03-15 | Teva Pharmaceutical Industries, Ltd. | N-ethyl-N-phenyl-1,2-dihydro-4,5-di-hydroxy-1-methyl-2-oxo-3-quinolinecarboxamide, preparation and uses thereof |
US20130259856A1 (en) * | 2012-03-27 | 2013-10-03 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with combination of laquinimod and dimethyl fumarate |
TW201350467A (zh) * | 2012-05-08 | 2013-12-16 | Teva Pharma | N-乙基-4-羥基-1-甲基-5-(甲基(2,3,4,5,6-五羥基己基)胺基)-2-側氧-n-苯基-1,2-二氫喹啉-3-甲醯胺 |
TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
US20130345257A1 (en) * | 2012-06-26 | 2013-12-26 | The Regents Of The University Of California | Composition for lupus nephritis and methods of making and using the same |
AR091706A1 (es) * | 2012-07-11 | 2015-02-25 | Teva Pharma | Formulaciones de laquinimod sin agentes alcalinizantes |
TW201410244A (zh) * | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療gaba媒介之疾病之拉喹莫德(laquinimod) |
TW201410243A (zh) * | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療大麻素受體型1(cb1)媒介之疾病之拉喹莫德(laquinimod) |
MX2015005632A (es) * | 2012-11-07 | 2016-02-05 | Teva Pharma | Sales de amina de laquinimod. |
AU2014216199A1 (en) * | 2013-02-15 | 2015-09-03 | Teva Pharmaceutical Industries Ltd. | Treatment of progressive forms of multiple sclerosis with laquinimod |
NZ630427A (en) | 2013-03-14 | 2017-06-30 | Teva Pharma | Crystals of laquinimod sodium and improved process for the manufacture thereof |
EP2968203A1 (en) | 2013-03-14 | 2016-01-20 | Teva Pharmaceutical Industries Ltd. | Transdermal formulations of laquinimod |
JP2016533323A (ja) * | 2013-09-27 | 2016-10-27 | テバ ファーマシューティカル インダストリーズ リミティド | 多発性硬化症の治療のためのラキニモド併用療法 |
EP3082814A4 (en) * | 2013-12-20 | 2017-06-21 | Teva Pharmaceutical Industries Ltd. | Use of laquinimod to delay huntington's disease progression |
EP3094330A4 (en) * | 2014-01-17 | 2017-09-27 | Teva Pharmaceutical Industries Ltd | Treatment of crohn's disease using low doses of laquinimod |
AU2015253330A1 (en) | 2014-04-29 | 2016-12-01 | Teva Pharmaceutical Industries Ltd. | Laquinimod for the treatment of relapsing-remitting multiple sclerosis (RRMS) patients with a high disability status |
CN110193014B (zh) * | 2019-06-06 | 2021-05-11 | 温州医科大学 | 一种注射用拉喹莫德胶束冻干制剂及制备方法、拉喹莫德注射制剂 |
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SE0201778D0 (sv) | 2002-06-12 | 2002-06-12 | Active Biotech Ab | Process for the manufacture of quinoline derivatives |
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US8980870B2 (en) * | 2002-09-24 | 2015-03-17 | Boehringer Ingelheim International Gmbh | Solid telmisartan pharmaceutical formulations |
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US8314124B2 (en) | 2004-02-06 | 2012-11-20 | Active Biotech Ab | Crystalline salts of quinoline compounds and methods for preparing them |
SE0400235D0 (sv) | 2004-02-06 | 2004-02-06 | Active Biotech Ab | New composition containing quinoline compounds |
UA92761C2 (ru) | 2005-10-19 | 2010-12-10 | Тева Фармасьютикл Индастриз, Лтд. | Кристаллы лаквинимода натрия и способ их изготовления |
AU2007258366B2 (en) | 2006-06-12 | 2012-10-25 | Active Biotech, Ab | Stable laquinimod preparations |
US20080087929A1 (en) * | 2006-10-11 | 2008-04-17 | Infineon Technologies Ag | Static random access memory with thin oxide capacitor |
SI2234485T1 (sl) | 2007-12-20 | 2014-03-31 | Teva Pharmaceutical Industries Ltd. | Stabilni lakvinimodni pripravki |
EA021227B1 (ru) | 2008-09-03 | 2015-05-29 | Тева Фармасьютикал Индастриз Лтд. | 2-оксо-1,2-дигидрохинолиновые модуляторы иммунной функции |
NZ597378A (en) | 2009-06-19 | 2014-08-29 | Teva Pharma | Treatment of multiple sclerosis with laquinimod |
ES2564931T3 (es) | 2009-07-30 | 2016-03-30 | Teva Pharmaceutical Industries Ltd. | Tratamiento de enfermedad de Crohn con laquinimod |
DK2467372T3 (en) | 2009-08-10 | 2016-08-22 | Teva Pharma | TREATMENT OF BDNF-RELATED DISEASES USING LAQUINIMOD |
PE20130613A1 (es) | 2010-03-03 | 2013-06-23 | Teva Pharma | Tratamiento de lupus nefritis usando laquinimod |
PT2542079E (pt) | 2010-03-03 | 2014-07-18 | Teva Pharma | Tratamento da artrite reumatoide com uma combinação de laquinimod e metotrexato |
SG183515A1 (en) | 2010-03-03 | 2012-10-30 | Teva Pharma | Treatment of lupus arthritis using laquinimod |
US20120010239A1 (en) | 2010-07-09 | 2012-01-12 | Ulf Tomas Fristedt | 5-chloro-4-hydroxy-1-methyl-2-oxo-n-phenyl-1,2-dihydroquinoline-3-carboxamide, salts and uses thereof |
KR20130092558A (ko) | 2010-07-09 | 2013-08-20 | 테바 파마슈티컬 인더스트리즈 리미티드 | 중수소화된 n-에틸-n-페닐-1,2-다이하이드로-4-하이드록시-5-클로로-1-메틸-2-옥소퀴놀린-3-카복스아마이드, 그의 염 및 용도 |
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2007
- 2007-06-12 AU AU2007258366A patent/AU2007258366B2/en active Active
- 2007-06-12 BR BRPI0713694-3A patent/BRPI0713694A2/pt not_active Application Discontinuation
- 2007-06-12 NZ NZ573846A patent/NZ573846A/en unknown
- 2007-06-12 AT AT07809468T patent/ATE532515T1/de active
- 2007-06-12 SI SI200730834T patent/SI2035001T1/sl unknown
- 2007-06-12 ZA ZA200810790A patent/ZA200810790B/xx unknown
- 2007-06-12 EP EP07809468A patent/EP2035001B1/en active Active
- 2007-06-12 UA UAA200900145A patent/UA96449C2/ru unknown
- 2007-06-12 CA CA2899472A patent/CA2899472C/en active Active
- 2007-06-12 AR ARP070102573A patent/AR061348A1/es unknown
- 2007-06-12 EA EA200870599A patent/EA018031B1/ru not_active IP Right Cessation
- 2007-06-12 US US11/811,810 patent/US7989473B2/en active Active
- 2007-06-12 CA CA2654982A patent/CA2654982C/en active Active
- 2007-06-12 CN CN2007800216771A patent/CN101466379B/zh not_active Expired - Fee Related
- 2007-06-12 KR KR1020167001876A patent/KR20160013273A/ko not_active Application Discontinuation
- 2007-06-12 MX MX2008015808A patent/MX2008015808A/es active IP Right Grant
- 2007-06-12 RS RS20120039A patent/RS52169B/en unknown
- 2007-06-12 KR KR1020097000323A patent/KR101495327B1/ko active IP Right Grant
- 2007-06-12 PL PL07809468T patent/PL2035001T3/pl unknown
- 2007-06-12 JP JP2009515443A patent/JP5226678B2/ja active Active
- 2007-06-12 WO PCT/US2007/013721 patent/WO2007146248A2/en active Application Filing
- 2007-06-12 KR KR1020147018170A patent/KR20140091778A/ko active Application Filing
- 2007-06-12 DK DK07809468.7T patent/DK2035001T3/da active
- 2007-06-12 TW TW096121085A patent/TWI400073B/zh not_active IP Right Cessation
- 2007-06-12 ES ES07809468T patent/ES2377149T3/es active Active
- 2007-06-12 PT PT07809468T patent/PT2035001E/pt unknown
- 2007-06-12 KR KR1020157014257A patent/KR20150065951A/ko not_active Application Discontinuation
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2008
- 2008-12-04 IL IL195724A patent/IL195724A/en active IP Right Grant
-
2009
- 2009-01-12 NO NO20090175A patent/NO342485B1/no not_active IP Right Cessation
- 2009-03-23 HK HK09102756.1A patent/HK1121971A1/xx not_active IP Right Cessation
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2011
- 2011-06-22 US US13/166,210 patent/US20110251235A1/en not_active Abandoned
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2012
- 2012-01-27 HR HR20120093T patent/HRP20120093T1/hr unknown
- 2012-02-07 CY CY20121100127T patent/CY1113003T1/el unknown
- 2012-08-07 US US13/568,940 patent/US8383645B2/en active Active
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