NO20081310L - Faste doseringsformer for valsartan og amlodipin, og fremgangsmater for fremstilling av samme - Google Patents

Faste doseringsformer for valsartan og amlodipin, og fremgangsmater for fremstilling av samme

Info

Publication number
NO20081310L
NO20081310L NO20081310A NO20081310A NO20081310L NO 20081310 L NO20081310 L NO 20081310L NO 20081310 A NO20081310 A NO 20081310A NO 20081310 A NO20081310 A NO 20081310A NO 20081310 L NO20081310 L NO 20081310L
Authority
NO
Norway
Prior art keywords
valsartan
amlodipine
dosage forms
solid dosage
preparing
Prior art date
Application number
NO20081310A
Other languages
English (en)
Norwegian (no)
Inventor
Robert Frank Wagner
Yatindra Joshi
Madhusudhan Pudipeddi
Gangadhar Sunkara
Li Ping
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37758280&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20081310(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20081310L publication Critical patent/NO20081310L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
NO20081310A 2005-08-17 2008-03-12 Faste doseringsformer for valsartan og amlodipin, og fremgangsmater for fremstilling av samme NO20081310L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70908305P 2005-08-17 2005-08-17
PCT/US2006/031699 WO2007022113A2 (en) 2005-08-17 2006-08-15 Solid dosage forms of valsartan and amlodipine and method of making the same

Publications (1)

Publication Number Publication Date
NO20081310L true NO20081310L (no) 2008-05-16

Family

ID=37758280

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20081310A NO20081310L (no) 2005-08-17 2008-03-12 Faste doseringsformer for valsartan og amlodipin, og fremgangsmater for fremstilling av samme

Country Status (22)

Country Link
US (3) US20080171086A1 (enExample)
EP (1) EP1917002A2 (enExample)
JP (2) JP2009504744A (enExample)
KR (3) KR20120135356A (enExample)
CN (1) CN101237859A (enExample)
AR (1) AR055120A1 (enExample)
AU (2) AU2006279670A1 (enExample)
BR (1) BRPI0614790A2 (enExample)
CA (1) CA2617367A1 (enExample)
EC (1) ECSP088188A (enExample)
GT (1) GT200600371A (enExample)
IL (1) IL189021A0 (enExample)
MA (1) MA29734B1 (enExample)
MX (1) MX2008002267A (enExample)
NO (1) NO20081310L (enExample)
NZ (1) NZ565020A (enExample)
PE (1) PE20070420A1 (enExample)
RU (2) RU2008109913A (enExample)
TN (1) TNSN08071A1 (enExample)
TW (1) TW200740432A (enExample)
WO (1) WO2007022113A2 (enExample)
ZA (1) ZA200800397B (enExample)

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CN102091069A (zh) * 2009-12-11 2011-06-15 浙江华海药业股份有限公司 缬沙坦和氨氯地平的复方制剂及其制备方法
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CN102283837A (zh) * 2011-07-29 2011-12-21 江苏省药物研究所有限公司 缬沙坦和氨氯地平复方的固体制剂的制备方法
CN102697778B (zh) * 2012-06-21 2014-04-30 上海医药集团股份有限公司 缬沙坦氨氯地平复方固体制剂及其制备方法
WO2013191668A1 (en) 2012-06-22 2013-12-27 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Compositions preventing hypertension comprising soluplus
WO2014058047A1 (ja) * 2012-10-12 2014-04-17 味の素株式会社 カルシウム拮抗薬／アンジオテンシンｉｉ受容体拮抗薬含有医薬製剤の製造方法
CN103006649B (zh) * 2012-12-27 2014-06-25 石家庄市华新药业有限责任公司 一种复方制剂缬沙坦氨氯地平片（ⅰ）及其制备方法
CZ2013783A3 (cs) 2013-10-08 2015-04-15 Zentiva, K. S Stabilní farmaceutická kompozice obsahující amlodipin a valsartan
MX380070B (es) * 2015-07-08 2025-03-11 Cj Healthcare Corp Una composición farmacéutica que comprende amlodipino, valsartán y rosuvastatina.
CN105232551A (zh) * 2015-11-19 2016-01-13 哈尔滨圣吉药业股份有限公司 一种缬沙坦/苯磺酸氨氯地平复方制剂及其制备方法
CN106176744A (zh) * 2016-07-13 2016-12-07 精华制药集团股份有限公司 缬沙坦氨氯地平胶囊在制备治疗脑中风的药物中的应用
ES3035030T3 (en) 2016-10-07 2025-08-28 Silvergate Pharmaceuticals Inc Amlodipine formulations
EP3522888A4 (en) * 2016-10-10 2020-06-10 Alembic Pharmaceuticals Limited STABLE PHARMACEUTICAL COMPOSITION WITH TELMISARTAN AND AMLODIPINE BESYLATE
CN109498626A (zh) * 2017-09-14 2019-03-22 北京万全德众医药生物技术有限公司 一种稳定的复方制剂缬沙坦氨氯地平处方及其制备方法
US10799453B2 (en) 2018-04-11 2020-10-13 Silvergate Pharmaceuticals, Inc. Amlodipine formulations
CN109260160A (zh) * 2018-08-30 2019-01-25 天津仁生医药科技有限公司 一种缬沙坦氨氯地平片剂及其制备方法
CN109010338B (zh) * 2018-09-13 2021-09-21 合肥合源药业有限公司 一种缬沙坦氨氯地平片的制备方法及缬沙坦氨氯地平片
CN109157526A (zh) * 2018-09-13 2019-01-08 合肥合源药业有限公司 一种缬沙坦氨氯地平复方制剂及其制备工艺
CN109394712B (zh) * 2018-11-23 2019-11-12 海南妙音春制药有限公司 一种缬沙坦氨氯地平复方片剂及其制备方法
WO2025162195A1 (zh) * 2024-01-30 2025-08-07 上海汇伦医药股份有限公司 包衣复方片剂
CN120392682A (zh) * 2024-01-30 2025-08-01 上海汇伦医药股份有限公司 速释组合物
CN119925284B (zh) * 2025-04-09 2025-07-11 杭州沐源生物医药科技有限公司 一种含有厄贝沙坦和氨氯地平的药物组合物及制备方法

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Also Published As

Publication number Publication date
CN101237859A (zh) 2008-08-06
GT200600371A (es) 2007-03-21
US20080171086A1 (en) 2008-07-17
KR20120078751A (ko) 2012-07-10
AR055120A1 (es) 2007-08-08
TNSN08071A1 (en) 2009-07-14
PE20070420A1 (es) 2007-05-21
AU2006279670A1 (en) 2007-02-22
EP1917002A2 (en) 2008-05-07
ECSP088188A (es) 2008-03-26
KR20120135356A (ko) 2012-12-12
JP2009504744A (ja) 2009-02-05
RU2008109913A (ru) 2009-09-27
ZA200800397B (en) 2009-03-25
KR20080034159A (ko) 2008-04-18
IL189021A0 (en) 2008-08-07
WO2007022113A2 (en) 2007-02-22
MX2008002267A (es) 2008-03-27
JP2013091660A (ja) 2013-05-16
US20120177733A1 (en) 2012-07-12
CA2617367A1 (en) 2007-02-22
US20100303906A1 (en) 2010-12-02
WO2007022113A3 (en) 2007-05-10
TW200740432A (en) 2007-11-01
MA29734B1 (fr) 2008-09-01
NZ565020A (en) 2011-07-29
AU2010227062A1 (en) 2010-11-04
BRPI0614790A2 (pt) 2011-04-12
RU2012131668A (ru) 2014-01-27

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