NO20080144L - Spiro-benzimidazoler som inhibitorer av magesyre og sekresjon - Google Patents

Spiro-benzimidazoler som inhibitorer av magesyre og sekresjon

Info

Publication number
NO20080144L
NO20080144L NO20080144A NO20080144A NO20080144L NO 20080144 L NO20080144 L NO 20080144L NO 20080144 A NO20080144 A NO 20080144A NO 20080144 A NO20080144 A NO 20080144A NO 20080144 L NO20080144 L NO 20080144L
Authority
NO
Norway
Prior art keywords
secretion
gastric acid
benzimidazoles
spiro
inhibitors
Prior art date
Application number
NO20080144A
Other languages
English (en)
Inventor
Jorg Senn-Bilfinger
Stefan Postius
Wolfgang-Alexander Simon
Wolfgang Kromer
Andreas Palmer
Wilm Buhr
Maria Vittoria Chiesa
Peter Jan Zimmermann
Christof Brehm
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of NO20080144L publication Critical patent/NO20080144L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Oppfinnelsen fremskaffer forbindelser med formel (1), hvor substituenter og symboler er som definert i beskrivelsen. Forbindelsene hemmer utskillelse av mavesyre.
NO20080144A 2005-06-16 2008-01-09 Spiro-benzimidazoler som inhibitorer av magesyre og sekresjon NO20080144L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05105330 2005-06-16
PCT/EP2006/063163 WO2006134111A1 (en) 2005-06-16 2006-06-13 Spiro-benzimidazoles as inhibitors of gastric acid secretion

Publications (1)

Publication Number Publication Date
NO20080144L true NO20080144L (no) 2008-01-14

Family

ID=35276210

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20080144A NO20080144L (no) 2005-06-16 2008-01-09 Spiro-benzimidazoler som inhibitorer av magesyre og sekresjon

Country Status (16)

Country Link
US (1) US20090093473A1 (no)
EP (1) EP1899338A1 (no)
JP (1) JP2008543808A (no)
KR (1) KR20080020675A (no)
CN (1) CN101193890A (no)
AR (1) AR057061A1 (no)
AU (1) AU2006259123A1 (no)
BR (1) BRPI0612010A2 (no)
CA (1) CA2627589A1 (no)
EA (1) EA200702584A1 (no)
IL (1) IL188011A0 (no)
MX (1) MX2007015088A (no)
NO (1) NO20080144L (no)
TW (1) TW200720273A (no)
WO (1) WO2006134111A1 (no)
ZA (1) ZA200709852B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2333266T3 (es) * 2007-02-22 2010-02-18 Indena S.P.A. Procedimiento para la preparacion de sal de acetato del ester metilico de (2r,3s)-3-fenilisoserina.
WO2008151927A2 (en) * 2007-06-15 2008-12-18 Nycomed Gmbh 6-n-substituted benz imidazole derivatives as acid pump antagonists
WO2011004882A1 (ja) 2009-07-09 2011-01-13 ラクオリア創薬株式会社 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤
AR103598A1 (es) 2015-02-02 2017-05-24 Forma Therapeutics Inc Ácidos bicíclicos[4,6,0]hidroxámicos como inhibidores de hdac
AU2016215432B2 (en) 2015-02-02 2020-07-30 Valo Early Discovery, Inc. 3-alkyl-4-amido-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
US10555935B2 (en) 2016-06-17 2020-02-11 Forma Therapeutics, Inc. 2-spiro-5- and 6-hydroxamic acid indanes as HDAC inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
AR043063A1 (es) * 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
AR043962A1 (es) * 2003-04-04 2005-08-17 Altana Pharma Ag Compuestos derivados de bencimidazol, medicamentos que los contienen y su uso para preparar dichos medicamentos.
US20040204453A1 (en) * 2003-04-14 2004-10-14 Pfizer Inc 4-Phenyl-piperidine compounds and their use as modulators of opioid receptors

Also Published As

Publication number Publication date
ZA200709852B (en) 2008-10-29
IL188011A0 (en) 2008-03-20
CN101193890A (zh) 2008-06-04
TW200720273A (en) 2007-06-01
AU2006259123A1 (en) 2006-12-21
WO2006134111A1 (en) 2006-12-21
AR057061A1 (es) 2007-11-14
AU2006259123A8 (en) 2008-04-03
US20090093473A1 (en) 2009-04-09
BRPI0612010A2 (pt) 2010-10-13
CA2627589A1 (en) 2006-12-21
EA200702584A1 (ru) 2008-06-30
KR20080020675A (ko) 2008-03-05
MX2007015088A (es) 2008-01-24
JP2008543808A (ja) 2008-12-04
EP1899338A1 (en) 2008-03-19

Similar Documents

Publication Publication Date Title
IS7721A (is) Píperidín-pýrídasón og þalasón sem PDE4 hemlar
NO20064632L (no) Tricykliske imidazopyridiner
WO2009046841A8 (de) Piperidin- und piperazinderivate zur behandlung von tumoren
NO20053242L (no) 4-substituerte benzimidazoler og deres anvendelse som inhibitorer av gastrisk sekresjon
EA200801428A1 (ru) Производные пиридиазинона для лечения опухолей
NO20064351L (no) Caspaseinhibitorer og anvendelser derav
MX2009009774A (es) Derivados de quinolina como fungicidas.
NO20082594L (no) Pyrimidinylbenzotiofenforbindelser
EA200701396A1 (ru) Триазолофталазины в качестве ингибиторов pde-2
EA200801608A1 (ru) Производные бензимидазолонкарбоновой кислоты
NO20084583L (no) Makrosykliske kinase-inhibitorer
NO20082209L (no) Homo- og heterocykliske forbindelser anvendbare som CETP-inhibitorer
NO20061789L (no) Aminopyridinderivater som induserbare NO-syntaseinhibitorer
EA200801365A1 (ru) Замещенные 5-фенил-3,6-дигидро-2-оксо-6h-1,3,4-тиадиазины
NO20082116L (no) Kjemisk fremgangsmate for fremstilling av en amido-fenoksybenzosyreforbindelse
NO20063220L (no) Tricykliske imidazopyridiner for anvendelse som gastriske sekresjonsinhibitorer
EA200801366A1 (ru) Производные 3,6-дигидро-2-оксо-6н-1,3,4-тиадиазина
NO20080144L (no) Spiro-benzimidazoler som inhibitorer av magesyre og sekresjon
NO20040604L (no) Trisykliske imidazolpyridiner
NO20054199L (no) 6-substituerte imidazopyraziner
TW200600502A (en) Novel 6-substituted benzimidazoles
NO20080839L (no) Isotopsubstituerte protonpumpeinhibitorer
NO20082105L (no) Pyrazoloisokinolinderivater
ATE419242T1 (de) Pyrrolidinylharnstoffderivate als angiogeneseinhibitoren
WO2006061380A3 (en) SUBSTITUTED IMIDAZO[4,5-b]PYRIDINES AS INHIBITORS OF GASTRIC ACID SECRETION

Legal Events

Date Code Title Description
CREP Change of representative

Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104

FC2A Withdrawal, rejection or dismissal of laid open patent application