TW200600502A - Novel 6-substituted benzimidazoles - Google Patents

Novel 6-substituted benzimidazoles

Info

Publication number
TW200600502A
TW200600502A TW094115928A TW94115928A TW200600502A TW 200600502 A TW200600502 A TW 200600502A TW 094115928 A TW094115928 A TW 094115928A TW 94115928 A TW94115928 A TW 94115928A TW 200600502 A TW200600502 A TW 200600502A
Authority
TW
Taiwan
Prior art keywords
novel
substituted benzimidazoles
benzimidazoles
substituted
compounds
Prior art date
Application number
TW094115928A
Other languages
Chinese (zh)
Inventor
Peter Jan Zimmermann
Wilm Buhr
Vittoria M Chiesa
Andreas Palmer
Christof Brehm
Wolfgang-Alexander Simon
Stefan Postius
Wolfgang Kromer
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of TW200600502A publication Critical patent/TW200600502A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides compounds of the formula 1, in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.
TW094115928A 2004-05-18 2005-05-17 Novel 6-substituted benzimidazoles TW200600502A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04102191 2004-05-18

Publications (1)

Publication Number Publication Date
TW200600502A true TW200600502A (en) 2006-01-01

Family

ID=34929111

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094115928A TW200600502A (en) 2004-05-18 2005-05-17 Novel 6-substituted benzimidazoles

Country Status (7)

Country Link
EP (1) EP1756067A1 (en)
JP (1) JP2007538047A (en)
AR (1) AR049168A1 (en)
AU (1) AU2005243434A1 (en)
CA (1) CA2566821A1 (en)
TW (1) TW200600502A (en)
WO (1) WO2005111000A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2619518A1 (en) * 2005-08-22 2007-03-01 Nycomed Gmbh Isotopically substituted benzimidazole derivatives
WO2007031860A1 (en) * 2005-09-15 2007-03-22 Pfizer Japan Inc. Indane substituted benzimidazoles and their use as acid pump inhibitors
WO2007072142A2 (en) * 2005-12-19 2007-06-28 Pfizer Japan Inc. Benzimidazole-5-carboxamide derivatives
DE602006014996D1 (en) * 2005-12-19 2010-07-29 Raqualia Pharma Inc CHROMIN-SUBSTITUTED BENZIMIDAZOLE AND THEIR USE AS ACID PUMPING INHIBITORS
KR20190057569A (en) * 2017-11-20 2019-05-29 제일약품주식회사 7-amino-1H-indole-5-carboxamide derivatives, and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8604566D0 (en) * 1986-10-27 1986-10-27 Haessle Ab NOVEL COMPUNDS
IL108520A (en) * 1993-02-15 1997-09-30 Byk Gulden Lomberg Chem Fab 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
WO1996004251A1 (en) * 1994-08-03 1996-02-15 Fujisawa Pharmaceutical Co., Ltd. Heterocyclic compound
SE9602286D0 (en) * 1996-06-10 1996-06-10 Astra Ab New compounds
AR043063A1 (en) * 2002-12-13 2005-07-13 Altana Pharma Ag 6-SUBSTITUTED BENCIMIDAZOLS AND THEIR USE AS INHIBITORS OF GASTRIC SECRETIONS

Also Published As

Publication number Publication date
JP2007538047A (en) 2007-12-27
AU2005243434A1 (en) 2005-11-24
CA2566821A1 (en) 2005-11-24
EP1756067A1 (en) 2007-02-28
WO2005111000A1 (en) 2005-11-24
AR049168A1 (en) 2006-07-05

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