TW200720273A - Pharmaceutically active spiro-benzimidazoles - Google Patents

Pharmaceutically active spiro-benzimidazoles

Info

Publication number
TW200720273A
TW200720273A TW095120998A TW95120998A TW200720273A TW 200720273 A TW200720273 A TW 200720273A TW 095120998 A TW095120998 A TW 095120998A TW 95120998 A TW95120998 A TW 95120998A TW 200720273 A TW200720273 A TW 200720273A
Authority
TW
Taiwan
Prior art keywords
benzimidazoles
pharmaceutically active
active spiro
spiro
compounds
Prior art date
Application number
TW095120998A
Other languages
English (en)
Inventor
Peter Jan Zimmermann
Jorg Senn-Bilfinger
Christof Brehm
Wilm Buhr
Maria Vittoria Chiesa
Wolfgang Kromer
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of TW200720273A publication Critical patent/TW200720273A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TW095120998A 2005-06-16 2006-06-13 Pharmaceutically active spiro-benzimidazoles TW200720273A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05105330 2005-06-16

Publications (1)

Publication Number Publication Date
TW200720273A true TW200720273A (en) 2007-06-01

Family

ID=35276210

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095120998A TW200720273A (en) 2005-06-16 2006-06-13 Pharmaceutically active spiro-benzimidazoles

Country Status (16)

Country Link
US (1) US20090093473A1 (zh)
EP (1) EP1899338A1 (zh)
JP (1) JP2008543808A (zh)
KR (1) KR20080020675A (zh)
CN (1) CN101193890A (zh)
AR (1) AR057061A1 (zh)
AU (1) AU2006259123A1 (zh)
BR (1) BRPI0612010A2 (zh)
CA (1) CA2627589A1 (zh)
EA (1) EA200702584A1 (zh)
IL (1) IL188011A0 (zh)
MX (1) MX2007015088A (zh)
NO (1) NO20080144L (zh)
TW (1) TW200720273A (zh)
WO (1) WO2006134111A1 (zh)
ZA (1) ZA200709852B (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2333266T3 (es) * 2007-02-22 2010-02-18 Indena S.P.A. Procedimiento para la preparacion de sal de acetato del ester metilico de (2r,3s)-3-fenilisoserina.
WO2008151927A2 (en) * 2007-06-15 2008-12-18 Nycomed Gmbh 6-n-substituted benz imidazole derivatives as acid pump antagonists
WO2011004882A1 (ja) 2009-07-09 2011-01-13 ラクオリア創薬株式会社 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤
AR103598A1 (es) 2015-02-02 2017-05-24 Forma Therapeutics Inc Ácidos bicíclicos[4,6,0]hidroxámicos como inhibidores de hdac
AU2016215432B2 (en) 2015-02-02 2020-07-30 Valo Early Discovery, Inc. 3-alkyl-4-amido-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors
US10555935B2 (en) 2016-06-17 2020-02-11 Forma Therapeutics, Inc. 2-spiro-5- and 6-hydroxamic acid indanes as HDAC inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
AR043063A1 (es) * 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
AR043962A1 (es) * 2003-04-04 2005-08-17 Altana Pharma Ag Compuestos derivados de bencimidazol, medicamentos que los contienen y su uso para preparar dichos medicamentos.
US20040204453A1 (en) * 2003-04-14 2004-10-14 Pfizer Inc 4-Phenyl-piperidine compounds and their use as modulators of opioid receptors

Also Published As

Publication number Publication date
ZA200709852B (en) 2008-10-29
IL188011A0 (en) 2008-03-20
CN101193890A (zh) 2008-06-04
AU2006259123A1 (en) 2006-12-21
WO2006134111A1 (en) 2006-12-21
AR057061A1 (es) 2007-11-14
AU2006259123A8 (en) 2008-04-03
US20090093473A1 (en) 2009-04-09
BRPI0612010A2 (pt) 2010-10-13
NO20080144L (no) 2008-01-14
CA2627589A1 (en) 2006-12-21
EA200702584A1 (ru) 2008-06-30
KR20080020675A (ko) 2008-03-05
MX2007015088A (es) 2008-01-24
JP2008543808A (ja) 2008-12-04
EP1899338A1 (en) 2008-03-19

Similar Documents

Publication Publication Date Title
TW200637853A (en) Fungicides
UA94833C2 (en) Substituted bicyclolactams
TW200700393A (en) Novel cis-2,4,5-triaryl-imidazolines
TN2010000101A1 (en) Fungicidal 2-alkylthio-2-quinolinyloxy -acetamide derivatives
WO2009046841A8 (de) Piperidin- und piperazinderivate zur behandlung von tumoren
WO2005087724A3 (en) Sulphonylpyrroles as hdac inhibitors
WO2009024342A3 (en) Novel microbiocides
WO2006072612A3 (en) Triazolophthalazines as pde2- inhibitors
WO2007084728A3 (en) 2-imino-benzimidazoles
UA88956C2 (ru) Синергическая фунгицидная комбинация действующих веществ
TW200745039A (en) Isotopically substituted pantoprazole
TW200700358A (en) Organic compounds
WO2007120333A3 (en) Tetracyclic kinase inhibitors
TW200621160A (en) Anti-termite agent
TW200602326A (en) Tricyclic imidazopyridines
WO2008151828A8 (en) Novel microbiocides
TW200720273A (en) Pharmaceutically active spiro-benzimidazoles
TW200613308A (en) Cyclobutanetetracarboxylate compound and preparation method thereof
DE60204701D1 (de) Tricyclische imidazopyridine
TW200600502A (en) Novel 6-substituted benzimidazoles
PL1845780T3 (pl) Zastosowanie pochodnych metylofenidatu
TW200637803A (en) Processes for the preparation of aminoethoxybenzyl alcohols
WO2006023586A3 (en) Guanylhydrazone compounds, compositions, methods of making and using
WO2005058325A8 (en) Tricyclic imidazopyridines for use as gastric secretion inhibitors
WO2005070927A3 (en) 1,2,4-triazolo[1,5-a] pyridines as gastric acid secretion inhibitors