NO20082105L - Pyrazoloisokinolinderivater - Google Patents

Pyrazoloisokinolinderivater

Info

Publication number
NO20082105L
NO20082105L NO20082105A NO20082105A NO20082105L NO 20082105 L NO20082105 L NO 20082105L NO 20082105 A NO20082105 A NO 20082105A NO 20082105 A NO20082105 A NO 20082105A NO 20082105 L NO20082105 L NO 20082105L
Authority
NO
Norway
Prior art keywords
pyrazoloisokinolinderivater
compounds
meanings
useful
formula
Prior art date
Application number
NO20082105A
Other languages
English (en)
Inventor
Marina Virgili Bernado
Carmen Almansa Rosales
Original Assignee
Palau Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Palau Pharma Sa filed Critical Palau Pharma Sa
Publication of NO20082105L publication Critical patent/NO20082105L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Nye forbindelser med formel I, hvor betydningene for de forskjellige substituenter er som beskrevet i beskrivelsen. Disse forbindelser er anvendelige som p38-kinaseinhibitorer.
NO20082105A 2005-11-25 2008-05-06 Pyrazoloisokinolinderivater NO20082105L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05381056 2005-11-25
PCT/EP2006/068815 WO2007060198A1 (en) 2005-11-25 2006-11-23 Pyrazoloisoquinoline derivatives

Publications (1)

Publication Number Publication Date
NO20082105L true NO20082105L (no) 2008-07-31

Family

ID=37672381

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082105A NO20082105L (no) 2005-11-25 2008-05-06 Pyrazoloisokinolinderivater

Country Status (15)

Country Link
US (1) US20080269209A1 (no)
EP (1) EP1960400A1 (no)
JP (1) JP2009517367A (no)
KR (1) KR20080070687A (no)
CN (1) CN101312974A (no)
AR (1) AR058223A1 (no)
AU (1) AU2006316435A1 (no)
BR (1) BRPI0618976A2 (no)
CA (1) CA2630907A1 (no)
IL (1) IL191138A0 (no)
NO (1) NO20082105L (no)
PE (1) PE20071086A1 (no)
RU (1) RU2008125858A (no)
TW (1) TW200804375A (no)
WO (1) WO2007060198A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008001932A1 (de) 2008-05-21 2009-11-26 Bayer Cropscience Ag Substiuierte Spiroisoxazoline
FR2944792B1 (fr) 2009-04-24 2011-05-20 Sanofi Aventis Derives de 1h-pyrazolo[4,3-c]isoquinoleines, leur preparation et leur application en therapeutique
US10131663B2 (en) 2016-10-24 2018-11-20 Astrazeneca Ab Chemical compounds
DK3494116T3 (da) 2017-01-30 2020-01-27 Astrazeneca Østrogenreceptormodulatorer
WO2020160321A1 (en) * 2019-01-30 2020-08-06 Yale University Compounds, compositions, and methods for treating fibrosis
CN113877483B (zh) * 2021-07-20 2023-11-24 烟台宁远药业有限公司 医药中间体卤代异喹啉类硼酸的低温连续合成装置与方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696143A (en) * 1994-09-20 1997-12-09 Talley; John J. Benz G! indazolyl derivatives for the treatment of inflammation
ATE415162T1 (de) * 2001-06-11 2008-12-15 Vertex Pharma Isochinolin-inhibitoren von p38
EP1438293A2 (en) * 2001-09-19 2004-07-21 Pharmacia Corporation Substituted pyrazolyl benzenesulfamide compounds for the treatment of inflammation
ES2281633T3 (es) * 2002-02-19 2007-10-01 Pfizer Italia S.R.L. Derivados triciclicos de pirazol, procedimiento para su preparacion y su uso como agentes antitumorales.
EP1644371B1 (en) * 2003-07-03 2008-02-13 Aventis Pharmaceuticals Inc. Pyrazoloisoquinoline derivatives as kinase inhibitors
CA2532800C (en) * 2003-07-23 2013-06-18 Exelixis, Inc. Anaplastic lymphoma kinase modulators and methods of use

Also Published As

Publication number Publication date
US20080269209A1 (en) 2008-10-30
TW200804375A (en) 2008-01-16
AU2006316435A1 (en) 2007-05-31
IL191138A0 (en) 2008-12-29
JP2009517367A (ja) 2009-04-30
KR20080070687A (ko) 2008-07-30
EP1960400A1 (en) 2008-08-27
AR058223A1 (es) 2008-01-23
CN101312974A (zh) 2008-11-26
RU2008125858A (ru) 2009-12-27
PE20071086A1 (es) 2007-11-19
WO2007060198A1 (en) 2007-05-31
BRPI0618976A2 (pt) 2011-09-20
CA2630907A1 (en) 2007-05-31

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Legal Events

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