NO20075399L - Benzimidazolerivat og anvendelse derav - Google Patents

Benzimidazolerivat og anvendelse derav

Info

Publication number
NO20075399L
NO20075399L NO20075399A NO20075399A NO20075399L NO 20075399 L NO20075399 L NO 20075399L NO 20075399 A NO20075399 A NO 20075399A NO 20075399 A NO20075399 A NO 20075399A NO 20075399 L NO20075399 L NO 20075399L
Authority
NO
Norway
Prior art keywords
methyl
benzimidazole derivative
oxo
pharmaceutical
benzimidazole
Prior art date
Application number
NO20075399A
Other languages
English (en)
Inventor
Takanobu Kuroita
Mami Ojima
Junko Ban
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of NO20075399L publication Critical patent/NO20075399L/no

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
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Abstract

Foreliggende oppfinnelse tilveiebringer (5-metyl-2-okso-l,3-dioksol-4-yl)metyl 2-syklopropyl-l-{[2'-(5-okso-4,5-dihydro-l,2,4-oksadiazol-3-yl)bifenyl-4-yl]metyl}-lH-benzimidazol-7-karboksylat, representert ved en formel som har overlegne egenskaper som et farmasøytisk middel, et salt derav, en krystall derav, et farmasøytisk middel som inneholder forbindelsen, og lignende,
NO20075399A 2005-03-30 2007-10-23 Benzimidazolerivat og anvendelse derav NO20075399L (no)

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JP2005099788 2005-03-30
JP2005198014 2005-07-06
PCT/JP2006/307170 WO2006107062A2 (en) 2005-03-30 2006-03-29 Benzimidazole derivative and use as angiotensin ii antagonist

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WO2007097452A1 (ja) * 2006-02-27 2007-08-30 Takeda Pharmaceutical Company Limited 医薬用ブリスターパッケージ
EP1990052B1 (en) 2006-02-27 2012-05-16 Takeda Pharmaceutical Company Limited Pharmaceutical package comprising 2-ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1h-benzimidazole-7-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl or 2-cyclopropyl-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1h-benzimidazole-7-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl and a desiccant.
JP5340925B2 (ja) * 2006-09-25 2013-11-13 武田薬品工業株式会社 医薬パッケージ
KR101126383B1 (ko) 2007-02-07 2012-04-12 교와 핫꼬 기린 가부시키가이샤 3환계 화합물
MX2011001150A (es) * 2008-07-31 2011-03-29 Takeda Pharmaceutical Composicion farmaceutica solida.
EP3081213B1 (en) 2008-08-06 2020-04-01 Kyowa Kirin Co., Ltd. Tricyclic compound
UY32126A (es) 2008-09-25 2010-04-30 Takeda Pharmaceutical Composición farmacéutica sólida
CA2840818C (en) * 2011-02-08 2018-12-11 Jubilant Life Sciences Limited An improved process for the preparation of azilsartan medoxomil
CZ304252B6 (cs) * 2011-04-11 2014-01-29 Zentiva, K. S. Způsob výroby 2-ethoxy-1-((2´-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)bifenyl-4-yl)methyl)-1H-benzo[d]imidazol-7-karboxylátů a jejich převedení na azilsartan
KR101275092B1 (ko) * 2011-05-19 2013-06-17 한미정밀화학주식회사 아질사르탄의 개선된 제조방법
CN102827153B (zh) * 2011-06-14 2016-10-05 江苏豪森药业集团有限公司 阿齐沙坦的晶型及其制备方法
JP6281735B2 (ja) * 2013-03-19 2018-02-21 トーアエイヨー株式会社 急性心不全治療薬の評価方法、及び、急性心不全モデルの作製方法

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HRP20080552A9 (en) 2009-08-31
HK1115584A1 (en) 2008-12-05
PE20061195A1 (es) 2006-12-21
DK1863801T3 (da) 2010-11-15
MA29438B1 (fr) 2008-05-02
EP1863801B1 (en) 2010-09-29
JP2008534434A (ja) 2008-08-28
WO2006107062A3 (en) 2006-12-14
SI1863801T1 (sl) 2010-12-31
RS20080510A (en) 2009-07-15
US20090054502A1 (en) 2009-02-26
IL185726A (en) 2012-07-31
CY1111168T1 (el) 2015-06-11
MY146254A (en) 2012-07-31
CR9432A (es) 2008-02-04
TW200724539A (en) 2007-07-01
CA2602624A1 (en) 2006-10-12
US20120172401A1 (en) 2012-07-05
BRPI0608944A2 (pt) 2010-11-16
HRP20080552A2 (en) 2009-03-31
GEP20115138B (en) 2011-01-10
NZ562887A (en) 2010-10-29
AR055755A1 (es) 2007-09-05
IL185726A0 (en) 2008-01-06
MEP33308A (en) 2010-10-10
AU2006231418A1 (en) 2006-10-12
AU2006231418B2 (en) 2011-10-13
RU2007139928A (ru) 2009-05-10
EP1863801A2 (en) 2007-12-12
KR20070116648A (ko) 2007-12-10
JP4795362B2 (ja) 2011-10-19
RU2407742C2 (ru) 2010-12-27
DE602006017183D1 (de) 2010-11-11
PL1863801T3 (pl) 2011-03-31
WO2006107062A2 (en) 2006-10-12
PT1863801E (pt) 2010-11-19
JP2011190265A (ja) 2011-09-29

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