MA29438B1 - Derive de benzimidazole et utilisation de celui-ci - Google Patents

Derive de benzimidazole et utilisation de celui-ci

Info

Publication number
MA29438B1
MA29438B1 MA30312A MA30312A MA29438B1 MA 29438 B1 MA29438 B1 MA 29438B1 MA 30312 A MA30312 A MA 30312A MA 30312 A MA30312 A MA 30312A MA 29438 B1 MA29438 B1 MA 29438B1
Authority
MA
Morocco
Prior art keywords
benzimidazole derivative
benzimidazole
derivative
Prior art date
Application number
MA30312A
Other languages
English (en)
Inventor
Takanobu Kuroita
Mami Ojima
Junko Ban
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of MA29438B1 publication Critical patent/MA29438B1/fr

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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    • A61P9/06—Antiarrhythmics
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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Abstract

S
MA30312A 2005-03-30 2007-10-25 Derive de benzimidazole et utilisation de celui-ci MA29438B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005099788 2005-03-30
JP2005198014 2005-07-06

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MA29438B1 true MA29438B1 (fr) 2008-05-02

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MA30312A MA29438B1 (fr) 2005-03-30 2007-10-25 Derive de benzimidazole et utilisation de celui-ci

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US (2) US20090054502A1 (fr)
EP (1) EP1863801B1 (fr)
JP (2) JP4795362B2 (fr)
KR (1) KR20070116648A (fr)
AR (1) AR055755A1 (fr)
AU (1) AU2006231418B2 (fr)
BR (1) BRPI0608944A2 (fr)
CA (1) CA2602624A1 (fr)
CR (1) CR9432A (fr)
CY (1) CY1111168T1 (fr)
DE (1) DE602006017183D1 (fr)
DK (1) DK1863801T3 (fr)
GE (1) GEP20115138B (fr)
HK (1) HK1115584A1 (fr)
HR (1) HRP20080552A9 (fr)
IL (1) IL185726A (fr)
MA (1) MA29438B1 (fr)
ME (1) MEP33308A (fr)
MY (1) MY146254A (fr)
NO (1) NO20075399L (fr)
NZ (1) NZ562887A (fr)
PE (1) PE20061195A1 (fr)
PL (1) PL1863801T3 (fr)
PT (1) PT1863801E (fr)
RS (1) RS20080510A (fr)
RU (1) RU2407742C2 (fr)
SI (1) SI1863801T1 (fr)
TW (1) TW200724539A (fr)
WO (1) WO2006107062A2 (fr)

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EP1990052B1 (fr) * 2006-02-27 2012-05-16 Takeda Pharmaceutical Company Limited Emballage pharmaceutique comprenant du 2-ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1h-benzimidazole-7-carboxylate de (5-methyl-2-oxo-1,3-dioxol-4-yl)methyle ou du 2-cyclopropyl-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1h-benzimidazole-7-carboxylate de (5-methyl-2-oxo-1,3-dioxol-4-yl)methyle et un agent deshydratant
WO2007097452A1 (fr) * 2006-02-27 2007-08-30 Takeda Pharmaceutical Company Limited Emballage-coque à usage médical
EP2068812B9 (fr) * 2006-09-25 2012-08-08 Takeda Pharmaceutical Company Limited Emballage médical
WO2008096829A1 (fr) 2007-02-07 2008-08-14 Kyowa Hakko Kirin Co., Ltd. Composés tricycliques
CN102164918B (zh) * 2008-07-31 2014-05-07 武田药品工业株式会社 固体药物组合物
WO2010016549A1 (fr) 2008-08-06 2010-02-11 協和発酵キリン株式会社 Composé tricyclique
TW201014850A (en) 2008-09-25 2010-04-16 Takeda Pharmaceutical Solid pharmaceutical composition
EP2673274B1 (fr) * 2011-02-08 2019-07-17 Jubilant Generics Limited Procédé amélioré pour la préparation d'azilsartan médoxomil
CZ304252B6 (cs) * 2011-04-11 2014-01-29 Zentiva, K. S. Způsob výroby 2-ethoxy-1-((2´-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)bifenyl-4-yl)methyl)-1H-benzo[d]imidazol-7-karboxylátů a jejich převedení na azilsartan
KR101275092B1 (ko) * 2011-05-19 2013-06-17 한미정밀화학주식회사 아질사르탄의 개선된 제조방법
CN102827153B (zh) * 2011-06-14 2016-10-05 江苏豪森药业集团有限公司 阿齐沙坦的晶型及其制备方法
JP6281735B2 (ja) * 2013-03-19 2018-02-21 トーアエイヨー株式会社 急性心不全治療薬の評価方法、及び、急性心不全モデルの作製方法

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US5250554A (en) * 1989-10-24 1993-10-05 Takeda Chemical Industries, Ltd. Benzimidazole derivatives useful as angiotensin II inhibitors
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
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US5602127A (en) * 1991-02-06 1997-02-11 Karl Thomae Gmbh (Alkanesultam-1-yl)-benzimidazol-1-yl)-1yl)-methyl-biphenyls useful as angiotensin-II antagonists
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Also Published As

Publication number Publication date
MEP33308A (en) 2010-10-10
JP2011190265A (ja) 2011-09-29
US20120172401A1 (en) 2012-07-05
NO20075399L (no) 2007-12-19
DK1863801T3 (da) 2010-11-15
WO2006107062A3 (fr) 2006-12-14
JP4795362B2 (ja) 2011-10-19
TW200724539A (en) 2007-07-01
CY1111168T1 (el) 2015-06-11
EP1863801A2 (fr) 2007-12-12
DE602006017183D1 (de) 2010-11-11
HRP20080552A9 (en) 2009-08-31
IL185726A (en) 2012-07-31
KR20070116648A (ko) 2007-12-10
US20090054502A1 (en) 2009-02-26
NZ562887A (en) 2010-10-29
AU2006231418B2 (en) 2011-10-13
CA2602624A1 (fr) 2006-10-12
CR9432A (es) 2008-02-04
IL185726A0 (en) 2008-01-06
PT1863801E (pt) 2010-11-19
MY146254A (en) 2012-07-31
RU2407742C2 (ru) 2010-12-27
RS20080510A (en) 2009-07-15
HRP20080552A2 (en) 2009-03-31
SI1863801T1 (sl) 2010-12-31
AU2006231418A1 (en) 2006-10-12
PL1863801T3 (pl) 2011-03-31
BRPI0608944A2 (pt) 2010-11-16
JP2008534434A (ja) 2008-08-28
PE20061195A1 (es) 2006-12-21
EP1863801B1 (fr) 2010-09-29
AR055755A1 (es) 2007-09-05
RU2007139928A (ru) 2009-05-10
HK1115584A1 (en) 2008-12-05
WO2006107062A2 (fr) 2006-10-12
GEP20115138B (en) 2011-01-10

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