TW200724539A - Benzimidazole derivative and use thereof - Google Patents

Benzimidazole derivative and use thereof

Info

Publication number
TW200724539A
TW200724539A TW095110870A TW95110870A TW200724539A TW 200724539 A TW200724539 A TW 200724539A TW 095110870 A TW095110870 A TW 095110870A TW 95110870 A TW95110870 A TW 95110870A TW 200724539 A TW200724539 A TW 200724539A
Authority
TW
Taiwan
Prior art keywords
methyl
benzimidazole derivative
oxo
pharmaceutical agent
nzimidazole
Prior art date
Application number
TW095110870A
Other languages
English (en)
Inventor
Takanobu Kuroita
Mami Ojima
Junko Ban
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of TW200724539A publication Critical patent/TW200724539A/zh

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
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TW095110870A 2005-03-30 2006-03-29 Benzimidazole derivative and use thereof TW200724539A (en)

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JP5047156B2 (ja) * 2006-02-27 2012-10-10 武田薬品工業株式会社 医薬パッケージ
EP2068812B9 (en) * 2006-09-25 2012-08-08 Takeda Pharmaceutical Company Limited Medicinal package
US8242151B2 (en) 2007-02-07 2012-08-14 Kyowa Hakko Kirin Co., Ltd. Tricyclic compounds
PE20110551A1 (es) * 2008-07-31 2011-09-02 Takeda Pharmaceutical Composicion farmaceutica solida que contiene un derivado de bencimidazol y un diuretico
WO2010016549A1 (ja) 2008-08-06 2010-02-11 協和発酵キリン株式会社 ３環系化合物
TW201014850A (en) 2008-09-25 2010-04-16 Takeda Pharmaceutical Solid pharmaceutical composition
JP2014505097A (ja) * 2011-02-08 2014-02-27 ジュビラント ライフ サイエンセズ リミテッド アジルサルタンメドキソミルの改良製造方法
CZ304252B6 (cs) * 2011-04-11 2014-01-29 Zentiva, K. S. Způsob výroby 2-ethoxy-1-((2´-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)bifenyl-4-yl)methyl)-1H-benzo[d]imidazol-7-karboxylátů a jejich převedení na azilsartan
KR101275092B1 (ko) * 2011-05-19 2013-06-17 한미정밀화학주식회사 아질사르탄의 개선된 제조방법
CN102827153B (zh) * 2011-06-14 2016-10-05 江苏豪森药业集团有限公司 阿齐沙坦的晶型及其制备方法
JP6281735B2 (ja) * 2013-03-19 2018-02-21 トーアエイヨー株式会社 急性心不全治療薬の評価方法、及び、急性心不全モデルの作製方法

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JP4795362B2 (ja) 2011-10-19
IL185726A0 (en) 2008-01-06
KR20070116648A (ko) 2007-12-10
NZ562887A (en) 2010-10-29
GEP20115138B (en) 2011-01-10
MA29438B1 (fr) 2008-05-02
PE20061195A1 (es) 2006-12-21
HRP20080552A9 (en) 2009-08-31
HRP20080552A2 (en) 2009-03-31
HK1115584A1 (en) 2008-12-05
MY146254A (en) 2012-07-31
DE602006017183D1 (de) 2010-11-11
EP1863801A2 (en) 2007-12-12
WO2006107062A3 (en) 2006-12-14
EP1863801B1 (en) 2010-09-29
AU2006231418B2 (en) 2011-10-13
CR9432A (es) 2008-02-04
BRPI0608944A2 (pt) 2010-11-16
PL1863801T3 (pl) 2011-03-31
CA2602624A1 (en) 2006-10-12
NO20075399L (no) 2007-12-19
AR055755A1 (es) 2007-09-05
RS20080510A (en) 2009-07-15
WO2006107062A2 (en) 2006-10-12
IL185726A (en) 2012-07-31
DK1863801T3 (da) 2010-11-15
US20120172401A1 (en) 2012-07-05
JP2008534434A (ja) 2008-08-28
PT1863801E (pt) 2010-11-19
JP2011190265A (ja) 2011-09-29
CY1111168T1 (el) 2015-06-11
SI1863801T1 (sl) 2010-12-31
RU2407742C2 (ru) 2010-12-27
US20090054502A1 (en) 2009-02-26
AU2006231418A1 (en) 2006-10-12
MEP33308A (en) 2010-10-10
RU2007139928A (ru) 2009-05-10

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