DK1863801T3 - Benzimidazolderivat og anvendelse deraf - Google Patents

Benzimidazolderivat og anvendelse deraf

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Publication number
DK1863801T3
DK1863801T3 DK06731118.3T DK06731118T DK1863801T3 DK 1863801 T3 DK1863801 T3 DK 1863801T3 DK 06731118 T DK06731118 T DK 06731118T DK 1863801 T3 DK1863801 T3 DK 1863801T3
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DK
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Prior art keywords
benzimidazole derivative
benzimidazole
derivative
Prior art date
Application number
DK06731118.3T
Other languages
English (en)
Inventor
Takanobu Kuroita
Mami Ojima
Junko Ban
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Application granted granted Critical
Publication of DK1863801T3 publication Critical patent/DK1863801T3/da

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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DK06731118.3T 2005-03-30 2006-03-29 Benzimidazolderivat og anvendelse deraf DK1863801T3 (da)

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WO2007097451A1 (ja) 2006-02-27 2007-08-30 Takeda Pharmaceutical Company Limited 医薬パッケージ
WO2007097452A1 (ja) * 2006-02-27 2007-08-30 Takeda Pharmaceutical Company Limited 医薬用ブリスターパッケージ
JP5340925B2 (ja) * 2006-09-25 2013-11-13 武田薬品工業株式会社 医薬パッケージ
EP1988091B1 (en) 2007-02-07 2015-06-10 Kyowa Hakko Kirin Co., Ltd. Tricyclic compounds
US9169238B2 (en) * 2008-07-31 2015-10-27 Takeda Pharmaceutical Company Limited Solid pharmaceutical composition
WO2010016549A1 (ja) 2008-08-06 2010-02-11 協和発酵キリン株式会社 ３環系化合物
UY32126A (es) * 2008-09-25 2010-04-30 Takeda Pharmaceutical Composición farmacéutica sólida
JP2014505097A (ja) * 2011-02-08 2014-02-27 ジュビラント ライフ サイエンセズ リミテッド アジルサルタンメドキソミルの改良製造方法
CZ304252B6 (cs) * 2011-04-11 2014-01-29 Zentiva, K. S. Způsob výroby 2-ethoxy-1-((2´-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)bifenyl-4-yl)methyl)-1H-benzo[d]imidazol-7-karboxylátů a jejich převedení na azilsartan
KR101275092B1 (ko) * 2011-05-19 2013-06-17 한미정밀화학주식회사 아질사르탄의 개선된 제조방법
CN102827153B (zh) * 2011-06-14 2016-10-05 江苏豪森药业集团有限公司 阿齐沙坦的晶型及其制备方法
JP6281735B2 (ja) * 2013-03-19 2018-02-21 トーアエイヨー株式会社 急性心不全治療薬の評価方法、及び、急性心不全モデルの作製方法

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US5250554A (en) * 1989-10-24 1993-10-05 Takeda Chemical Industries, Ltd. Benzimidazole derivatives useful as angiotensin II inhibitors
IL95975A (en) * 1989-10-24 1997-06-10 Takeda Chemical Industries Ltd N-benzyl- 2-alkylbenzimidazole derivatives, their production and pharmaceutical compositions containing them
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
US6004989A (en) * 1990-04-27 1999-12-21 Takeda Chemical Industries, Ltd. Benzimidazole derivatives, their production and use
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US5594003A (en) * 1991-02-06 1997-01-14 Dr. Karl Thomae Gmbh Tetrahydroimidazo[1,2-a]pyridin-2-yl-(benzimidazol-1-yl)-methyl-biphenyls useful as angiotensin-II antagonists
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IL102183A (en) * 1991-06-27 1999-11-30 Takeda Chemical Industries Ltd The heterocyclic compounds are converted into biphenyl groups, their production and the pharmaceutical compositions containing them
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PL342684A1 (en) * 1998-03-04 2001-07-02 Takeda Chemical Industries Ltd Preperation featured by reterded release of aii antagonist, production and application of such preparation
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US7157584B2 (en) * 2004-02-25 2007-01-02 Takeda Pharmaceutical Company Limited Benzimidazole derivative and use thereof

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NO20075399L (no) 2007-12-19
DE602006017183D1 (de) 2010-11-11
EP1863801B1 (en) 2010-09-29
GEP20115138B (en) 2011-01-10
PL1863801T3 (pl) 2011-03-31
MEP33308A (en) 2010-10-10
RU2407742C2 (ru) 2010-12-27
CR9432A (es) 2008-02-04
PT1863801E (pt) 2010-11-19
WO2006107062A3 (en) 2006-12-14
AU2006231418A1 (en) 2006-10-12
US20090054502A1 (en) 2009-02-26
KR20070116648A (ko) 2007-12-10
MY146254A (en) 2012-07-31
PE20061195A1 (es) 2006-12-21
AR055755A1 (es) 2007-09-05
HK1115584A1 (en) 2008-12-05
NZ562887A (en) 2010-10-29
IL185726A (en) 2012-07-31
JP2011190265A (ja) 2011-09-29
WO2006107062A2 (en) 2006-10-12
MA29438B1 (fr) 2008-05-02
RU2007139928A (ru) 2009-05-10
RS20080510A (en) 2009-07-15
TW200724539A (en) 2007-07-01
CY1111168T1 (el) 2015-06-11
AU2006231418B2 (en) 2011-10-13
JP4795362B2 (ja) 2011-10-19
CA2602624A1 (en) 2006-10-12
IL185726A0 (en) 2008-01-06
BRPI0608944A2 (pt) 2010-11-16
SI1863801T1 (sl) 2010-12-31
US20120172401A1 (en) 2012-07-05
HRP20080552A2 (en) 2009-03-31
JP2008534434A (ja) 2008-08-28
HRP20080552A9 (en) 2009-08-31
EP1863801A2 (en) 2007-12-12

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