ATE469134T1 - Pharmazeutisch aktive diazepane - Google Patents

Pharmazeutisch aktive diazepane

Info

Publication number
ATE469134T1
ATE469134T1 AT06742609T AT06742609T ATE469134T1 AT E469134 T1 ATE469134 T1 AT E469134T1 AT 06742609 T AT06742609 T AT 06742609T AT 06742609 T AT06742609 T AT 06742609T AT E469134 T1 ATE469134 T1 AT E469134T1
Authority
AT
Austria
Prior art keywords
pharmaceutically active
diazepanes
lfa
activity
active diazepanes
Prior art date
Application number
AT06742609T
Other languages
English (en)
Inventor
Berndt Oberhauser
Dieter Scholz
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE469134T1 publication Critical patent/ATE469134T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
AT06742609T 2005-04-19 2006-04-19 Pharmazeutisch aktive diazepane ATE469134T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0507918.1A GB0507918D0 (en) 2005-04-19 2005-04-19 Organic compounds
PCT/EP2006/003583 WO2006111371A1 (en) 2005-04-19 2006-04-19 Pharmaceutically active diazepanes

Publications (1)

Publication Number Publication Date
ATE469134T1 true ATE469134T1 (de) 2010-06-15

Family

ID=34630941

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06742609T ATE469134T1 (de) 2005-04-19 2006-04-19 Pharmazeutisch aktive diazepane

Country Status (17)

Country Link
US (1) US20080300237A1 (de)
EP (2) EP1874739B1 (de)
JP (1) JP2008538357A (de)
KR (2) KR20100017724A (de)
CN (1) CN101163685A (de)
AT (1) ATE469134T1 (de)
AU (1) AU2006237177A1 (de)
BR (1) BRPI0610856A2 (de)
CA (1) CA2600774A1 (de)
DE (1) DE602006014530D1 (de)
ES (1) ES2345628T3 (de)
GB (1) GB0507918D0 (de)
MX (1) MX2007013007A (de)
PL (1) PL1874739T3 (de)
PT (1) PT1874739E (de)
RU (1) RU2007142498A (de)
WO (1) WO2006111371A1 (de)

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AU2016274175B2 (en) 2015-06-12 2021-02-18 Mackay Medical Foundation The Presbyterian Church In Taiwan Mackay Memorial Hospital Methods and polypeptides for modulation of immunoresponse
CA3044526A1 (en) 2016-12-07 2018-06-14 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
CN116712540A (zh) 2016-12-14 2023-09-08 比奥拉治疗股份有限公司 使用整联蛋白抑制剂治疗胃肠道疾病
CN107759606B (zh) * 2017-11-29 2018-12-21 南京诺希生物科技有限公司 具有抗肿瘤活性的氮杂环烯烃并二氮卓药物分子及其制备方法
US20230033021A1 (en) 2018-06-20 2023-02-02 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an integrin inhibitor
EP3883636A1 (de) 2018-11-19 2021-09-29 Progenity, Inc. Einnehmbare vorrichtung zur abgabe eines therapeutikums an den magen-darm-trakt
EP4309722A2 (de) 2019-12-13 2024-01-24 Biora Therapeutics, Inc. Einnehmbare vorrichtung zur abgabe eines therapeutischen mittels an den magen-darm-trakt

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998002441A2 (en) 1996-07-12 1998-01-22 Ariad Pharmaceuticals, Inc. Non immunosuppressive antifungal rapalogs
EP1212331B1 (de) 1999-08-24 2004-04-21 Ariad Gene Therapeutics, Inc. 28-epirapaloge
ECSP003707A (es) * 1999-10-13 2002-05-23 Novartis Ag Diazepanes
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ES2345628T3 (es) 2010-09-28
JP2008538357A (ja) 2008-10-23
CA2600774A1 (en) 2006-10-26
GB0507918D0 (en) 2005-05-25
WO2006111371A1 (en) 2006-10-26
EP1874739B1 (de) 2010-05-26
PT1874739E (pt) 2010-07-27
EP1874739A1 (de) 2008-01-09
EP2206704A1 (de) 2010-07-14
RU2007142498A (ru) 2009-05-27
AU2006237177A1 (en) 2006-10-26
PL1874739T3 (pl) 2010-10-29
CN101163685A (zh) 2008-04-16
MX2007013007A (es) 2008-01-11
US20080300237A1 (en) 2008-12-04
DE602006014530D1 (de) 2010-07-08
BRPI0610856A2 (pt) 2010-08-03
KR20070121768A (ko) 2007-12-27

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