CY1112483T1 - Αγωνιστες gpcr πιπεριδινης - Google Patents
Αγωνιστες gpcr πιπεριδινηςInfo
- Publication number
- CY1112483T1 CY1112483T1 CY20111101161T CY111101161T CY1112483T1 CY 1112483 T1 CY1112483 T1 CY 1112483T1 CY 20111101161 T CY20111101161 T CY 20111101161T CY 111101161 T CY111101161 T CY 111101161T CY 1112483 T1 CY1112483 T1 CY 1112483T1
- Authority
- CY
- Cyprus
- Prior art keywords
- gpcr agonists
- piperidine
- piperidine gpcr
- agonists
- obesity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
Οι ενώσεις τύπου (Ι) ή φαρμακευτικά άλατα αυτών, είναι αγωνιστές GPCR και είναι χρήσιμες για την αγωγή της παχυσαρκίας και του διαβήτη.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0700123A GB0700123D0 (en) | 2007-01-04 | 2007-01-04 | GPCR agonists |
GB0719760A GB0719760D0 (en) | 2007-10-10 | 2007-10-10 | GPCR agonists |
EP08702095A EP2114933B1 (en) | 2007-01-04 | 2008-01-04 | Piperidine gpcr agonists |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1112483T1 true CY1112483T1 (el) | 2015-12-09 |
Family
ID=39203133
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20111101161T CY1112483T1 (el) | 2007-01-04 | 2011-11-25 | Αγωνιστες gpcr πιπεριδινης |
Country Status (17)
Country | Link |
---|---|
US (1) | US20100048632A1 (el) |
EP (2) | EP2114933B1 (el) |
JP (1) | JP2010514828A (el) |
AT (1) | ATE523507T1 (el) |
BR (1) | BRPI0806498A2 (el) |
CA (1) | CA2674348A1 (el) |
CY (1) | CY1112483T1 (el) |
DK (1) | DK2114933T3 (el) |
EA (1) | EA015129B1 (el) |
ES (1) | ES2373181T3 (el) |
HK (1) | HK1135703A1 (el) |
HR (1) | HRP20110852T1 (el) |
PL (1) | PL2114933T3 (el) |
PT (1) | PT2114933E (el) |
RS (1) | RS52065B (el) |
SI (1) | SI2114933T1 (el) |
WO (1) | WO2008081204A1 (el) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CL2008000017A1 (es) * | 2007-01-04 | 2008-08-01 | Prosidion Ltd | Compuestos derivados de heterociclos de nitrogeno y oxigeno, agonistas de gpcr; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la obesidad, diabetes, sindrome metabolico, hiperlipidemia, toleranci |
JP2010539152A (ja) | 2007-09-10 | 2010-12-16 | プロシディオン・リミテッド | 代謝障害の治療のための化合物 |
GB0812648D0 (en) * | 2008-07-10 | 2008-08-20 | Prosidion Ltd | Compounds |
GB0812649D0 (en) * | 2008-07-10 | 2008-08-20 | Prosidion Ltd | Compounds |
GB0904284D0 (en) | 2009-03-12 | 2009-04-22 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
GB0904287D0 (en) | 2009-03-12 | 2009-04-22 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
GB0904285D0 (en) | 2009-03-12 | 2009-04-22 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
JP2012530758A (ja) | 2009-06-24 | 2012-12-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規化合物、医薬組成物及びそれに関する方法 |
US8293729B2 (en) | 2009-06-24 | 2012-10-23 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical composition and methods relating thereto |
WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
WO2011113947A1 (en) | 2010-03-18 | 2011-09-22 | Boehringer Ingelheim International Gmbh | Combination of a gpr119 agonist and the dpp-iv inhibitor linagliptin for use in the treatment of diabetes and related conditions |
GB201006166D0 (en) | 2010-04-14 | 2010-05-26 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
GB201006167D0 (en) | 2010-04-14 | 2010-05-26 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
ITMI20100770A1 (it) | 2010-05-03 | 2011-11-04 | Dipharma Francis Srl | Procedimento per la preparazione di 3-(4-piridinil)-propanolo e suoi intermedi |
TW201209054A (en) | 2010-05-28 | 2012-03-01 | Prosidion Ltd | Novel compounds |
ITMI20100984A1 (it) | 2010-05-31 | 2011-12-01 | Dipharma Francis Srl | Procedimento per la preparazione di ossadiazoli |
WO2011157827A1 (de) | 2010-06-18 | 2011-12-22 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
CN103189360A (zh) | 2010-09-01 | 2013-07-03 | 艾尼纳制药公司 | 5-ht2c激动剂的非吸湿性盐 |
IN2013DN02552A (el) | 2010-09-01 | 2015-08-07 | Arena Pharm Inc | |
CN103189053A (zh) | 2010-09-01 | 2013-07-03 | 艾尼纳制药公司 | 用于体重控制的5-ht2c激动剂的调节释放剂型 |
SG188364A1 (en) | 2010-09-01 | 2013-04-30 | Arena Pharm Inc | Salts of lorcaserin with optically active acids |
GB201114389D0 (en) | 2011-08-22 | 2011-10-05 | Prosidion Ltd | Novel compounds |
WO2012066077A1 (en) | 2010-11-18 | 2012-05-24 | Prosidion Limited | 1,4 di substituted pyrrolidine - 3 - yl -amine derivatives and their use for the treatment of metabolic disorders |
EA031618B1 (ru) | 2011-06-09 | 2019-01-31 | Ризен Фармасьютикалз Са | Соединения-модуляторы gpr-119 |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
KR101535954B1 (ko) | 2012-06-12 | 2015-07-10 | 주식회사 종근당 | Gpr119 활성의 효능제로서의 피페리딘 유도체 |
AU2014354488B2 (en) | 2013-11-26 | 2017-08-24 | Chong Kun Dang Pharmaceutical Corp. | Amide derivatives for GPR119 agonist |
KR101726819B1 (ko) | 2014-10-27 | 2017-04-13 | 동아에스티 주식회사 | Gpr119 작용 활성을 갖는 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 약제학적 조성물 |
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AU2006264651A1 (en) | 2005-06-30 | 2007-01-11 | Prosidion Limited | G-protein coupled receptor agonists |
EP1907384A2 (en) | 2005-06-30 | 2008-04-09 | Prosidion Limited | Gpcr agonists |
JP5114395B2 (ja) | 2005-06-30 | 2013-01-09 | プロシディオン・リミテッド | Gpcrアゴニスト |
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-
2008
- 2008-01-04 AT AT08702095T patent/ATE523507T1/de active
- 2008-01-04 RS RS20110523A patent/RS52065B/en unknown
- 2008-01-04 WO PCT/GB2008/050010 patent/WO2008081204A1/en active Application Filing
- 2008-01-04 BR BRPI0806498-9A2A patent/BRPI0806498A2/pt not_active IP Right Cessation
- 2008-01-04 ES ES08702095T patent/ES2373181T3/es active Active
- 2008-01-04 PL PL08702095T patent/PL2114933T3/pl unknown
- 2008-01-04 US US12/522,015 patent/US20100048632A1/en not_active Abandoned
- 2008-01-04 EP EP08702095A patent/EP2114933B1/en active Active
- 2008-01-04 CA CA002674348A patent/CA2674348A1/en not_active Abandoned
- 2008-01-04 EA EA200900877A patent/EA015129B1/ru not_active IP Right Cessation
- 2008-01-04 EP EP11174256A patent/EP2377863A1/en not_active Withdrawn
- 2008-01-04 SI SI200830454T patent/SI2114933T1/sl unknown
- 2008-01-04 DK DK08702095.4T patent/DK2114933T3/da active
- 2008-01-04 JP JP2009544447A patent/JP2010514828A/ja active Pending
- 2008-01-04 PT PT08702095T patent/PT2114933E/pt unknown
-
2010
- 2010-04-16 HK HK10103731.6A patent/HK1135703A1/xx not_active IP Right Cessation
-
2011
- 2011-11-15 HR HR20110852T patent/HRP20110852T1/hr unknown
- 2011-11-25 CY CY20111101161T patent/CY1112483T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2674348A1 (en) | 2008-07-10 |
EP2114933B1 (en) | 2011-09-07 |
RS52065B (en) | 2012-06-30 |
SI2114933T1 (sl) | 2012-01-31 |
BRPI0806498A2 (pt) | 2014-04-22 |
PL2114933T3 (pl) | 2012-02-29 |
HK1135703A1 (en) | 2010-06-11 |
US20100048632A1 (en) | 2010-02-25 |
WO2008081204A1 (en) | 2008-07-10 |
PT2114933E (pt) | 2011-12-20 |
DK2114933T3 (da) | 2012-01-02 |
HRP20110852T1 (hr) | 2011-12-31 |
EA200900877A1 (ru) | 2010-02-26 |
ES2373181T3 (es) | 2012-02-01 |
ATE523507T1 (de) | 2011-09-15 |
EA015129B1 (ru) | 2011-06-30 |
JP2010514828A (ja) | 2010-05-06 |
EP2377863A1 (en) | 2011-10-19 |
EP2114933A1 (en) | 2009-11-11 |
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