NO20074443L - Fremgangsmate for svak fordelingskromatografi - Google Patents
Fremgangsmate for svak fordelingskromatografiInfo
- Publication number
- NO20074443L NO20074443L NO20074443A NO20074443A NO20074443L NO 20074443 L NO20074443 L NO 20074443L NO 20074443 A NO20074443 A NO 20074443A NO 20074443 A NO20074443 A NO 20074443A NO 20074443 L NO20074443 L NO 20074443L
- Authority
- NO
- Norway
- Prior art keywords
- procedure
- distribution chromatography
- weak distribution
- weak
- chromatography
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/30—Partition chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
- B01D15/327—Reversed phase with hydrophobic interaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
- B01D15/3828—Ligand exchange chromatography, e.g. complexation, chelation or metal interaction chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
Denne oppfinnelsen vedrører metoder for anvendelse av svak fordelingskromatografi for rensning av et produkt fra et lastet fluid som inneholder én eller flere urenheter. Videre vedrører oppfinnelsen metoder for svak fordelingskromatografi som er definert ved utførelsesbetingelser som forårsaker at et medium binder minst 1 mg produkt pr. ml medium, eller, alternativt, definert ved en fordelingskoeffisient på minst 0,1. ?? ?? ?? ?? 1
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66043705P | 2005-03-11 | 2005-03-11 | |
PCT/US2006/008919 WO2006099308A2 (en) | 2005-03-11 | 2006-03-10 | A method of weak partitioning chromatography |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20074443L true NO20074443L (no) | 2007-09-27 |
Family
ID=36992346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20074443A NO20074443L (no) | 2005-03-11 | 2007-09-03 | Fremgangsmate for svak fordelingskromatografi |
Country Status (21)
Country | Link |
---|---|
US (3) | US8067182B2 (no) |
EP (1) | EP1869065B1 (no) |
JP (1) | JP5199063B2 (no) |
KR (2) | KR101482791B1 (no) |
CN (2) | CN104610422A (no) |
AU (1) | AU2006223180B2 (no) |
BR (1) | BRPI0608584B8 (no) |
CA (1) | CA2601062C (no) |
CR (1) | CR9377A (no) |
DK (1) | DK1869065T3 (no) |
ES (1) | ES2797480T3 (no) |
HK (1) | HK1210476A1 (no) |
HU (1) | HUE049797T2 (no) |
IL (1) | IL185687A (no) |
MX (1) | MX2007011129A (no) |
NO (1) | NO20074443L (no) |
PL (1) | PL1869065T3 (no) |
PT (1) | PT1869065T (no) |
RU (1) | RU2457214C2 (no) |
SI (1) | SI1869065T1 (no) |
WO (1) | WO2006099308A2 (no) |
Families Citing this family (67)
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CN104610422A (zh) | 2005-03-11 | 2015-05-13 | 惠氏公司 | 弱分配层析的方法 |
JP2010510963A (ja) * | 2006-06-14 | 2010-04-08 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | セラミックヒドロキシアパタイトを使用する抗体の精製方法 |
ES2755386T5 (es) | 2006-08-28 | 2023-04-05 | Ares Trading Sa | Proceso para la purificación de proteínas que contienen fragmentos Fc |
CL2007002615A1 (es) * | 2006-09-08 | 2008-04-18 | Wyeth Corp | Metodos para aislar o purificar un producto que comprende poner el producto enlazado en contacto con al menos una solucion de lavado que comprende arginina y luego eluir el producto; y dicho producto. |
WO2008033517A2 (en) | 2006-09-13 | 2008-03-20 | Abbott Laboratories | Cell culture improvements |
US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
PL2078071T3 (pl) * | 2006-11-08 | 2015-07-31 | Wyeth Llc | Racjonalnie opracowane pożywki do hodowli komórek |
PL2840090T3 (pl) * | 2007-10-30 | 2018-07-31 | Genentech, Inc. | Oczyszczanie przeciwciał za pomocą chromatografii kationowymiennej |
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WO2010030222A1 (en) * | 2008-09-12 | 2010-03-18 | Ge Healthcare Bio-Sciences Ab | Enhanced protein aggregate removal with multimodal anion exchangers in the presence of protein-excluded zwitterions |
US20100069617A1 (en) * | 2008-09-12 | 2010-03-18 | Ge Healthcare Bio-Sciences Ab | Enhanced protein aggregate removal by mixed mode chromatography on hydrophobic interaction media in the presence of protein-excluded zwitterions |
EP2921501A1 (en) * | 2008-10-20 | 2015-09-23 | Abbvie Inc. | Isolation and purification of antibodies using Protein A affinity chromatography |
CN104974251A (zh) | 2008-10-20 | 2015-10-14 | Abbvie公司 | 在抗体纯化过程中的病毒灭活 |
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EP2702077A2 (en) | 2011-04-27 | 2014-03-05 | AbbVie Inc. | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
US10221210B2 (en) | 2011-07-20 | 2019-03-05 | Zepteon, Incorporated | Polypeptide separation methods |
ES2717536T3 (es) | 2011-11-02 | 2019-06-21 | Hoffmann La Roche | Cromatografía de sobrecarga y elución |
SG10201701224UA (en) | 2012-03-12 | 2017-04-27 | Merck Patent Gmbh | Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
WO2013158279A1 (en) * | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Protein purification methods to reduce acidic species |
WO2013176754A1 (en) | 2012-05-24 | 2013-11-28 | Abbvie Inc. | Novel purification of antibodies using hydrophobic interaction chromatography |
CN104507952B (zh) * | 2012-05-30 | 2018-08-10 | 生物辐射实验室股份有限公司 | 基于磷灰石的色谱树脂的原位恢复 |
EP2855504B1 (en) * | 2012-05-31 | 2018-10-24 | Agency For Science, Technology And Research | Chromatographic purification of immunoglobulin g preparations with particles having multimodal functionalities |
US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
WO2014035475A1 (en) | 2012-09-02 | 2014-03-06 | Abbvie Inc. | Methods to control protein heterogeneity |
EP2931400B1 (en) | 2012-12-14 | 2021-07-07 | Cytiva BioProcess R&D AB | Method for cleaning of packed bed chromatography columns |
AU2013381687A1 (en) | 2013-03-12 | 2015-09-24 | Abbvie Inc. | Human antibodies that bind human TNF-alpha and methods of preparing the same |
US10023608B1 (en) | 2013-03-13 | 2018-07-17 | Amgen Inc. | Protein purification methods to remove impurities |
US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
WO2014159579A1 (en) | 2013-03-14 | 2014-10-02 | Abbvie Inc. | MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE |
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US20150139988A1 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
WO2015088677A1 (en) | 2013-12-12 | 2015-06-18 | Emd Millipore Corporation | Protein separations using an acrylamide containing filter |
EP3157689B1 (en) | 2014-06-23 | 2021-04-28 | Bio-Rad Laboratories, Inc. | Apatite pretreatment |
EP3157551B1 (en) | 2014-06-23 | 2023-02-15 | Bio-Rad Laboratories, Inc. | Apatite in-situ restoration |
EP3487868A4 (en) | 2016-07-25 | 2020-07-29 | Cephalon, Inc. | WASHING PAD FOR AFFINITY CHROMATOGRAPHY |
CN111902720A (zh) | 2018-03-21 | 2020-11-06 | 沃特世科技公司 | 基于非抗体高亲和力的样品制备、吸附剂、装置和方法 |
JP6951051B2 (ja) * | 2018-05-24 | 2021-10-20 | HOYA Technosurgical株式会社 | 吸着剤の生産方法 |
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WO2020172658A1 (en) | 2019-02-24 | 2020-08-27 | Bristol-Myers Squibb Company | Methods of isolating a protein |
WO2020191369A1 (en) | 2019-03-21 | 2020-09-24 | Codiak Biosciences, Inc. | Process for preparing extracellular vesicles |
WO2021154908A1 (en) * | 2020-01-29 | 2021-08-05 | Merck Sharp & Dohme Corp. | Methods of separating host cell lipases from an anti-lag3 antibody production |
US20230366794A1 (en) | 2020-09-23 | 2023-11-16 | Codiak Biosciences, Inc. | Process for preparing extracellular vesicles |
WO2022066928A2 (en) | 2020-09-23 | 2022-03-31 | Codiak Biosciences, Inc. | Process for preparing extracellular vesicles |
IL310556A (en) | 2021-08-23 | 2024-03-01 | Genentech Inc | Purification processes using cation exchange chromatography for drug-antibody conjugates |
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GB0304576D0 (en) * | 2003-02-28 | 2003-04-02 | Lonza Biologics Plc | Protein a chromatography |
JP4496168B2 (ja) * | 2003-07-28 | 2010-07-07 | 株式会社リバース・プロテオミクス研究所 | 非特異的物質の除去方法 |
ATE462716T1 (de) | 2003-10-24 | 2010-04-15 | Amgen Inc | Verfahren zur aufreinigung von proteinen in einer durchflussfraktion aus der chromatographie mit hydrophoben wechselwirkungen |
CN1898266B (zh) | 2003-10-27 | 2011-09-21 | 惠氏公司 | 使用羟磷灰石层析除去高分子量聚集体 |
CN104610422A (zh) | 2005-03-11 | 2015-05-13 | 惠氏公司 | 弱分配层析的方法 |
-
2006
- 2006-03-10 CN CN201410849296.4A patent/CN104610422A/zh active Pending
- 2006-03-10 MX MX2007011129A patent/MX2007011129A/es active IP Right Grant
- 2006-03-10 EP EP06738028.7A patent/EP1869065B1/en active Active
- 2006-03-10 JP JP2008501028A patent/JP5199063B2/ja active Active
- 2006-03-10 PT PT67380287T patent/PT1869065T/pt unknown
- 2006-03-10 AU AU2006223180A patent/AU2006223180B2/en active Active
- 2006-03-10 WO PCT/US2006/008919 patent/WO2006099308A2/en active Application Filing
- 2006-03-10 ES ES06738028T patent/ES2797480T3/es active Active
- 2006-03-10 HU HUE06738028A patent/HUE049797T2/hu unknown
- 2006-03-10 KR KR20077020848A patent/KR101482791B1/ko active IP Right Grant
- 2006-03-10 PL PL06738028T patent/PL1869065T3/pl unknown
- 2006-03-10 RU RU2007132851/10A patent/RU2457214C2/ru not_active Application Discontinuation
- 2006-03-10 CA CA2601062A patent/CA2601062C/en active Active
- 2006-03-10 US US11/372,054 patent/US8067182B2/en active Active
- 2006-03-10 SI SI200632376T patent/SI1869065T1/sl unknown
- 2006-03-10 BR BRPI0608584A patent/BRPI0608584B8/pt active IP Right Grant
- 2006-03-10 KR KR1020137028820A patent/KR101660575B1/ko active IP Right Grant
- 2006-03-10 DK DK06738028.7T patent/DK1869065T3/da active
- 2006-03-10 CN CNA200680016391XA patent/CN101175765A/zh active Pending
- 2006-08-28 US US11/510,634 patent/US20070054390A1/en not_active Abandoned
-
2007
- 2007-09-03 NO NO20074443A patent/NO20074443L/no not_active Application Discontinuation
- 2007-09-03 IL IL185687A patent/IL185687A/en active IP Right Grant
- 2007-09-12 CR CR9377A patent/CR9377A/es not_active Application Discontinuation
-
2011
- 2011-11-28 US US13/305,045 patent/US9144755B2/en active Active
-
2015
- 2015-11-12 HK HK15111155.1A patent/HK1210476A1/xx unknown
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