NO20076067L - Metoder for syntese av substituerte 3-cyanokinoliner og mellomprodukter av denne - Google Patents

Metoder for syntese av substituerte 3-cyanokinoliner og mellomprodukter av denne

Info

Publication number
NO20076067L
NO20076067L NO20076067A NO20076067A NO20076067L NO 20076067 L NO20076067 L NO 20076067L NO 20076067 A NO20076067 A NO 20076067A NO 20076067 A NO20076067 A NO 20076067A NO 20076067 L NO20076067 L NO 20076067L
Authority
NO
Norway
Prior art keywords
cyanoquinolines
methods
substituted
intermediates
synthesis
Prior art date
Application number
NO20076067A
Other languages
English (en)
Inventor
Warren Chew
Gloria Karen Cheal
Jacqueline Francesca Lunetta
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37037465&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20076067(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20076067L publication Critical patent/NO20076067L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Oppfinnelsen angår metoder for fremstilling av substituerte 3-cyanokinoliner, omfattende forbindelser i henhold til følgende formel: Metodene er egnet for fremstilling i stor skala, unngår anvendelse av kromatografiske separeringer, og gir et stabilt produkt med høy renhet mer effektivt enn tidligere teknikk.
NO20076067A 2005-05-25 2007-11-26 Metoder for syntese av substituerte 3-cyanokinoliner og mellomprodukter av denne NO20076067L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68439105P 2005-05-25 2005-05-25
PCT/US2006/016215 WO2006127207A1 (en) 2005-05-25 2006-04-28 Methods of synthesizing substituted 3-cyanoquinolines and intermediates thereof

Publications (1)

Publication Number Publication Date
NO20076067L true NO20076067L (no) 2007-12-21

Family

ID=37037465

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20076067A NO20076067L (no) 2005-05-25 2007-11-26 Metoder for syntese av substituerte 3-cyanokinoliner og mellomprodukter av denne

Country Status (19)

Country Link
US (1) US20060270668A1 (no)
EP (1) EP1883631A1 (no)
JP (1) JP2008545688A (no)
KR (1) KR20080016671A (no)
CN (1) CN101203494A (no)
AR (1) AR053872A1 (no)
AU (1) AU2006249600A1 (no)
BR (1) BRPI0610147A2 (no)
CA (1) CA2609186A1 (no)
CR (1) CR9544A (no)
GT (1) GT200600213A (no)
IL (1) IL187532A0 (no)
NO (1) NO20076067L (no)
PA (1) PA8676201A1 (no)
PE (1) PE20061417A1 (no)
RU (1) RU2007143161A (no)
TW (1) TW200716557A (no)
WO (1) WO2006127207A1 (no)
ZA (1) ZA200710148B (no)

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Also Published As

Publication number Publication date
AR053872A1 (es) 2007-05-23
PE20061417A1 (es) 2007-01-20
PA8676201A1 (es) 2009-03-31
CA2609186A1 (en) 2006-11-30
IL187532A0 (en) 2008-03-20
AU2006249600A1 (en) 2006-11-30
CN101203494A (zh) 2008-06-18
JP2008545688A (ja) 2008-12-18
EP1883631A1 (en) 2008-02-06
ZA200710148B (en) 2008-09-25
KR20080016671A (ko) 2008-02-21
TW200716557A (en) 2007-05-01
CR9544A (es) 2008-03-07
RU2007143161A (ru) 2009-07-10
US20060270668A1 (en) 2006-11-30
WO2006127207A1 (en) 2006-11-30
BRPI0610147A2 (pt) 2010-06-01
GT200600213A (es) 2007-01-12

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