EA200700168A1 - Производные замещенной циклической мочевины, их получение и их фармацевтическое применение в качестве ингибиторов киназы - Google Patents

Производные замещенной циклической мочевины, их получение и их фармацевтическое применение в качестве ингибиторов киназы

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Publication number
EA200700168A1
EA200700168A1 EA200700168A EA200700168A EA200700168A1 EA 200700168 A1 EA200700168 A1 EA 200700168A1 EA 200700168 A EA200700168 A EA 200700168A EA 200700168 A EA200700168 A EA 200700168A EA 200700168 A1 EA200700168 A1 EA 200700168A1
Authority
EA
Eurasian Patent Office
Prior art keywords
derivatives
obtaining
kinase inhibitors
substituted cyclic
cyclic urea
Prior art date
Application number
EA200700168A
Other languages
English (en)
Inventor
Хартмут Штробель
Свен Руф
Доминик Лесюисс
Консепсьон Немесек
Юссеф Эль-Амад
Жак Може
Штефан Гюссреген
Курт Риттер
Жан-Люк Маллерон
Original Assignee
Авентис Фарма С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34931288&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200700168(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Авентис Фарма С.А. filed Critical Авентис Фарма С.А.
Publication of EA200700168A1 publication Critical patent/EA200700168A1/ru

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    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
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    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
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    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
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    • A61P17/00Drugs for dermatological disorders
    • A61P17/18Antioxidants, e.g. antiradicals
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    • A61P19/00Drugs for skeletal disorders
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
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    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Изобретение относится к продуктам формулы (I).
EA200700168A 2004-07-27 2005-07-25 Производные замещенной циклической мочевины, их получение и их фармацевтическое применение в качестве ингибиторов киназы EA200700168A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04291903A EP1621535A1 (en) 2004-07-27 2004-07-27 Substituted cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
PCT/EP2005/008722 WO2006010643A1 (en) 2004-07-27 2005-07-25 Substituted cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors

Publications (1)

Publication Number Publication Date
EA200700168A1 true EA200700168A1 (ru) 2007-06-29

Family

ID=34931288

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200700168A EA200700168A1 (ru) 2004-07-27 2005-07-25 Производные замещенной циклической мочевины, их получение и их фармацевтическое применение в качестве ингибиторов киназы

Country Status (19)

Country Link
US (1) US20080021029A1 (ru)
EP (2) EP1621535A1 (ru)
JP (1) JP2008508230A (ru)
KR (1) KR20070038531A (ru)
CN (1) CN101010314A (ru)
AR (1) AR050181A1 (ru)
AU (1) AU2005266462A1 (ru)
BR (1) BRPI0513901A (ru)
CA (1) CA2572970A1 (ru)
EA (1) EA200700168A1 (ru)
IL (1) IL180488A0 (ru)
MA (1) MA28756B1 (ru)
MX (1) MX2007001025A (ru)
NO (1) NO20071074L (ru)
PE (1) PE20060573A1 (ru)
TW (1) TW200617002A (ru)
UY (1) UY29038A1 (ru)
WO (1) WO2006010643A1 (ru)
ZA (1) ZA200700709B (ru)

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FR2896504B1 (fr) 2006-01-23 2012-07-13 Aventis Pharma Sa Nouveaux derives d'uree cyclique, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases
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FR2850652B1 (fr) * 2003-01-31 2008-05-30 Aventis Pharma Sa Nouveaux derives d'uree cyclique, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases
EP1621536A1 (en) * 2004-07-27 2006-02-01 Aventis Pharma S.A. Amino cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
FR2896504B1 (fr) * 2006-01-23 2012-07-13 Aventis Pharma Sa Nouveaux derives d'uree cyclique, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases

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AU2005266462A1 (en) 2006-02-02
CA2572970A1 (en) 2006-02-02
ZA200700709B (en) 2008-11-26
US20080021029A1 (en) 2008-01-24
EP1773809A1 (en) 2007-04-18
EP1621535A1 (en) 2006-02-01
AR050181A1 (es) 2006-10-04
IL180488A0 (en) 2007-06-03
MA28756B1 (fr) 2007-07-02
BRPI0513901A (pt) 2008-05-20
UY29038A1 (es) 2006-02-24
CN101010314A (zh) 2007-08-01
PE20060573A1 (es) 2006-07-22
TW200617002A (en) 2006-06-01
NO20071074L (no) 2007-04-27
WO2006010643A1 (en) 2006-02-02
KR20070038531A (ko) 2007-04-10
JP2008508230A (ja) 2008-03-21
MX2007001025A (es) 2007-04-16

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