NO20062428L - Kombinasjoner for HCV-behandling - Google Patents

Kombinasjoner for HCV-behandling

Info

Publication number
NO20062428L
NO20062428L NO20062428A NO20062428A NO20062428L NO 20062428 L NO20062428 L NO 20062428L NO 20062428 A NO20062428 A NO 20062428A NO 20062428 A NO20062428 A NO 20062428A NO 20062428 L NO20062428 L NO 20062428L
Authority
NO
Norway
Prior art keywords
hepatitis
relates
combinations
virus
combination
Prior art date
Application number
NO20062428A
Other languages
English (en)
Inventor
Robert Perni
Roger D Tung
Gurudatt Chandorkar
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of NO20062428L publication Critical patent/NO20062428L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2292—Thymosin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Abstract

Foreliggende oppfinnelse vedrører ko-administasjon av en hepatitt C virus NS3/4A-proteaseinhibitor og en cytokrom P450-monooksygenaseinhibitor. Kombinasjonen virker ved å gripe irm i livssyklusen til hepatitt C-viruset og er derfor nyttig som en antiviral terapi. Som sådan kan kombinasjonen anvendes for å behandle eller forebygge hepatitt C-infeksjoner i pasienter, oppflrmelsen vedrører også sammensetninger omfattende kombinasjonen av inhibitorer. Oppflrmelsen vedrører også kit og farmasøytiske pakker omfattende en hepatitt C virus NS3/4Aproteaseinhibitor og en cytokrom P450-monooksygenaseinhibitor. Oppflrmelsen vedrører også fremgangsmåter for fremstilling av disse sammensetningene, kombinasjonene, kitene og pakkene.
NO20062428A 2003-10-27 2006-05-29 Kombinasjoner for HCV-behandling NO20062428L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51485303P 2003-10-27 2003-10-27
PCT/US2004/035549 WO2005042020A2 (en) 2003-10-27 2004-10-27 Combinations for hcv treatment

Publications (1)

Publication Number Publication Date
NO20062428L true NO20062428L (no) 2006-05-29

Family

ID=34549356

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062428A NO20062428L (no) 2003-10-27 2006-05-29 Kombinasjoner for HCV-behandling

Country Status (22)

Country Link
US (3) US20060003942A1 (no)
EP (1) EP1677827B1 (no)
JP (1) JP2007509950A (no)
KR (1) KR20060120162A (no)
CN (1) CN1893978A (no)
AT (1) ATE416789T1 (no)
AU (1) AU2004285503A1 (no)
BR (1) BRPI0415935A (no)
CA (1) CA2543696A1 (no)
CY (1) CY1110176T1 (no)
DE (1) DE602004018363D1 (no)
DK (1) DK1677827T3 (no)
ES (1) ES2319775T3 (no)
IL (1) IL175211A0 (no)
MX (1) MXPA06004723A (no)
NO (1) NO20062428L (no)
PL (1) PL1677827T3 (no)
PT (1) PT1677827E (no)
RU (1) RU2006118359A (no)
SI (1) SI1677827T1 (no)
WO (1) WO2005042020A2 (no)
ZA (1) ZA200603863B (no)

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Also Published As

Publication number Publication date
US20100015090A1 (en) 2010-01-21
PT1677827E (pt) 2009-03-13
WO2005042020A2 (en) 2005-05-12
ES2319775T3 (es) 2009-05-12
DK1677827T3 (da) 2009-03-30
MXPA06004723A (es) 2006-07-05
AU2004285503A1 (en) 2005-05-12
ZA200603863B (en) 2007-11-28
DE602004018363D1 (de) 2009-01-22
JP2007509950A (ja) 2007-04-19
CY1110176T1 (el) 2015-01-14
CA2543696A1 (en) 2005-05-12
US20060003942A1 (en) 2006-01-05
CN1893978A (zh) 2007-01-10
KR20060120162A (ko) 2006-11-24
WO2005042020A3 (en) 2005-06-23
SI1677827T1 (sl) 2009-06-30
ATE416789T1 (de) 2008-12-15
IL175211A0 (en) 2006-09-05
PL1677827T3 (pl) 2009-06-30
BRPI0415935A (pt) 2007-01-02
RU2006118359A (ru) 2007-12-10
EP1677827B1 (en) 2008-12-10
EP1677827A2 (en) 2006-07-12
US20120114604A1 (en) 2012-05-10

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