MX346239B - Composiciones y metodos de polipeptidos-complejo de quelato de oligonucleotido. - Google Patents

Composiciones y metodos de polipeptidos-complejo de quelato de oligonucleotido.

Info

Publication number
MX346239B
MX346239B MX2014014021A MX2014014021A MX346239B MX 346239 B MX346239 B MX 346239B MX 2014014021 A MX2014014021 A MX 2014014021A MX 2014014021 A MX2014014021 A MX 2014014021A MX 346239 B MX346239 B MX 346239B
Authority
MX
Mexico
Prior art keywords
methods
chelate complex
polypeptide compositions
oligonucleotide chelate
polypeptide
Prior art date
Application number
MX2014014021A
Other languages
English (en)
Other versions
MX2014014021A (es
Inventor
Andrew Vaillant
Michel Bazinet
Original Assignee
Replicor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49581470&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX346239(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Replicor Inc filed Critical Replicor Inc
Publication of MX2014014021A publication Critical patent/MX2014014021A/es
Publication of MX346239B publication Critical patent/MX346239B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2292—Thymosin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/217—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)

Abstract

La presente invención se refiere a una composición farmacéutica que contiene un complejo de quelato de oligonucleótido y al menos un polipéptido o polipéptido pegilado. La presente descripción también describe composiciones farmacéuticas adicionales y métodos para el tratamiento de enfermedades que incluyen infecciones virales.
MX2014014021A 2012-05-18 2013-05-17 Composiciones y metodos de polipeptidos-complejo de quelato de oligonucleotido. MX346239B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261648711P 2012-05-18 2012-05-18
US201261695035P 2012-08-30 2012-08-30
PCT/CA2013/050379 WO2013170386A1 (en) 2012-05-18 2013-05-17 Oligonucleotide chelate complex-polypeptide compositions and methods

Publications (2)

Publication Number Publication Date
MX2014014021A MX2014014021A (es) 2015-02-10
MX346239B true MX346239B (es) 2017-03-13

Family

ID=49581470

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014014021A MX346239B (es) 2012-05-18 2013-05-17 Composiciones y metodos de polipeptidos-complejo de quelato de oligonucleotido.

Country Status (34)

Country Link
US (1) US9492506B2 (es)
EP (1) EP2849798B1 (es)
JP (1) JP2015517504A (es)
KR (1) KR102068109B1 (es)
CN (1) CN104349793B (es)
AU (1) AU2013262416B2 (es)
BR (1) BR112014028654A2 (es)
CA (1) CA2873529C (es)
CL (1) CL2014003134A1 (es)
CO (1) CO7131387A2 (es)
CR (1) CR20140527A (es)
CY (1) CY1124345T1 (es)
DK (1) DK2849798T3 (es)
DO (1) DOP2014000264A (es)
EA (1) EA035967B1 (es)
EC (1) ECSP14027694A (es)
ES (1) ES2873844T3 (es)
HK (1) HK1204279A1 (es)
HR (1) HRP20210840T1 (es)
HU (1) HUE054875T2 (es)
IL (1) IL235548B (es)
LT (1) LT2849798T (es)
MX (1) MX346239B (es)
MY (1) MY168778A (es)
NZ (1) NZ703095A (es)
PH (1) PH12014502551B1 (es)
PL (1) PL2849798T3 (es)
PT (1) PT2849798T (es)
RS (1) RS62030B1 (es)
SG (1) SG11201407599SA (es)
SI (1) SI2849798T1 (es)
TW (1) TWI635864B (es)
WO (1) WO2013170386A1 (es)
ZA (1) ZA201408674B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2619314T3 (es) 2007-05-11 2017-06-26 Adynxx, Inc. Expresión génica y dolor
JP6251247B2 (ja) 2012-05-10 2017-12-20 エーダイニクス インコーポレイテッド 活性成分の送達のための製剤
CN104837501B (zh) 2012-08-30 2018-11-02 里普利科股份有限公司 治疗乙型肝炎及丁型肝炎感染的方法
MD4760C8 (ro) 2014-07-10 2022-02-28 Replicor Inc. Compoziţii şi metode de tratament al infecţiilor provocate de viruşii hepatitei B şi hepatitei D
JP6705807B2 (ja) 2014-08-15 2020-06-03 エーダイニクス インコーポレイテッド 疼痛を治療するためのオリゴヌクレオチドデコイ
US11166976B2 (en) 2018-11-08 2021-11-09 Aligos Therapeutics, Inc. S-antigen transport inhibiting oligonucleotide polymers and methods
BR112021008539A2 (pt) * 2018-11-08 2021-08-03 Aligos Therapeutics, Inc. polímeros de oligonucleotídeos e métodos de inibição de transporte de antígeno s

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2769114B2 (ja) * 1993-10-29 1998-06-25 サイクローン・ファーマシューティカルズ ミニマルｂ型肝炎感染症治療用医薬組成物
UA78726C2 (en) * 2001-11-01 2007-04-25 Sciclone Pharmaceuticals Inc Pharmaceutical composition of thymosin alpha 1 conjugated with polyethylene glycol, method for production, and method for treatment
MXPA05002791A (es) * 2002-09-13 2005-12-05 Replicor Inc Oligonucleotidos antivirales complementarios sin secuencia.
WO2004076474A2 (en) * 2003-02-26 2004-09-10 Intermune, Inc. Polyethylene glycol modified interferon compositions and methods of use thereof
PT1677827E (pt) * 2003-10-27 2009-03-13 Vertex Pharma Associações para o tratamento do vhc
WO2006042418A1 (en) * 2004-10-19 2006-04-27 Replicor Inc. Antiviral oligonucleotides
WO2007022642A2 (en) 2005-08-25 2007-03-01 Replicor Inc. Anti-inflammatory molecules and their uses
US7776818B2 (en) * 2005-09-29 2010-08-17 S-Cell Biosciences, Inc. Methods to treat T-cell disorders using TISF
US20090215873A1 (en) * 2005-09-29 2009-08-27 Andrew Vaillant Therapeutic Molecules and their Uses
GB0715383D0 (en) * 2007-08-08 2007-09-19 Asterion Ltd Interferon
WO2009065181A1 (en) * 2007-11-21 2009-05-28 Apollo Life Sciences Limited Nanostructures suitable for delivery of agents
WO2009076679A2 (en) * 2007-12-13 2009-06-18 Alnylam Pharmaceuticals Inc. Methods and compositions for prevention or treatment of rsv infection
US8361980B2 (en) * 2008-03-07 2013-01-29 Santaris Pharma A/S Pharmaceutical compositions for treatment of microRNA related diseases
CN103221541B (zh) * 2009-05-28 2017-03-01 库尔纳公司 通过抑制抗病毒基因的天然反义转录物来治疗抗病毒基因相关疾病
CN102762215A (zh) * 2009-10-16 2012-10-31 葛兰素集团有限公司 Hbv反义抑制剂
JP5775581B2 (ja) * 2010-08-20 2015-09-09 レプリコール インコーポレーティッド オリゴヌクレオチドキレート錯体
CN104837501B (zh) 2012-08-30 2018-11-02 里普利科股份有限公司 治疗乙型肝炎及丁型肝炎感染的方法

Also Published As

Publication number Publication date
CL2014003134A1 (es) 2015-02-13
EA035967B1 (ru) 2020-09-07
EA201401278A1 (ru) 2015-04-30
BR112014028654A2 (pt) 2017-10-10
TWI635864B (zh) 2018-09-21
DOP2014000264A (es) 2015-01-31
PH12014502551A1 (en) 2015-01-21
AU2013262416B2 (en) 2017-05-11
ZA201408674B (en) 2016-01-27
US9492506B2 (en) 2016-11-15
US20130309201A1 (en) 2013-11-21
IL235548A0 (en) 2015-01-29
CR20140527A (es) 2014-12-15
EP2849798A1 (en) 2015-03-25
PL2849798T3 (pl) 2021-10-18
HRP20210840T1 (hr) 2021-08-06
EP2849798B1 (en) 2021-04-07
PH12014502551B1 (en) 2015-01-21
CA2873529C (en) 2020-08-18
NZ703095A (en) 2016-07-29
KR102068109B1 (ko) 2020-01-21
DK2849798T3 (da) 2021-05-31
CA2873529A1 (en) 2013-11-21
MX2014014021A (es) 2015-02-10
ECSP14027694A (es) 2015-12-31
CO7131387A2 (es) 2014-12-01
CY1124345T1 (el) 2022-07-22
HK1204279A1 (en) 2015-11-13
SG11201407599SA (en) 2014-12-30
MY168778A (en) 2018-12-04
TW201408308A (zh) 2014-03-01
KR20150013309A (ko) 2015-02-04
JP2015517504A (ja) 2015-06-22
SI2849798T1 (sl) 2021-08-31
WO2013170386A1 (en) 2013-11-21
AU2013262416A1 (en) 2014-12-18
HUE054875T2 (hu) 2021-10-28
RS62030B1 (sr) 2021-07-30
CN104349793A (zh) 2015-02-11
LT2849798T (lt) 2021-08-10
IL235548B (en) 2019-07-31
EP2849798A4 (en) 2016-03-09
PT2849798T (pt) 2021-05-18
CN104349793B (zh) 2017-11-10
ES2873844T3 (es) 2021-11-04

Similar Documents

Publication Publication Date Title
PH12015500274A1 (en) Alkylpyrimidine derivatives for the treatment of viral infections and further diseases
IN2015DN01156A (es)
PH12014502551B1 (en) Oligonucleotide chelate complex-polypeptide compositions and methods
TN2015000278A1 (en) Autotaxin inhibitors
PH12015500713A1 (en) Acylaminopyrimidine derivatives for the treatment of viral infections and further diseases
MX2016013689A (es) Compuestos 4-amino-imidazoquinolina.
EP2872151A4 (en) ACELLULAR PRO-TOLEROGENIC COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF AUTOIMMUNE DISEASES
PH12014501738A1 (en) Piperidino-pyrimidine derivatives for the treatment of viral infections
JO3357B1 (ar) مركبات إيميدازوبيروليدينون
MY172292A (en) Vectors and sequences for the treatment of diseases
PH12015500724B1 (en) 1, 2, 4-triazine derivatives for the treatment of viral infections
MX349004B (es) Nuevos compuestos.
MX2015011193A (es) Compuestos antivirales.
IN2014CN00572A (es)
MX2015011198A (es) Compuestos antivirales.
MX2015010892A (es) Compuestos antivirales.
MX2015011125A (es) Compuestos antivirales.
MX2015011126A (es) Compuestos antivirales.
IN2014DN10683A (es)
CU20140133A7 (es) Composiciones y métodos de polipéptidos-complejo de quelato de oligonucleótido
GB201114923D0 (en) Immunogenic proteins and compositions
ZA201407866B (en) Composition for the prevention and treatment of viral infections caused by retroviruses

Legal Events

Date Code Title Description
FG Grant or registration