NO20052568L - Fremgangsmate for fremstilling av makrolidforbindelse - Google Patents

Fremgangsmate for fremstilling av makrolidforbindelse

Info

Publication number
NO20052568L
NO20052568L NO20052568A NO20052568A NO20052568L NO 20052568 L NO20052568 L NO 20052568L NO 20052568 A NO20052568 A NO 20052568A NO 20052568 A NO20052568 A NO 20052568A NO 20052568 L NO20052568 L NO 20052568L
Authority
NO
Norway
Prior art keywords
compound
macrolide compound
streptomyces
represented
formula
Prior art date
Application number
NO20052568A
Other languages
English (en)
Norwegian (no)
Other versions
NO20052568D0 (no
Inventor
Satoshi Yamamoto
Susumu Takeda
Takashi Sakai
Takasi Nakashima
Akifumi Okuda
Katsura Kaneko
Taira Kato
Naota Kawamura
Original Assignee
Mercian Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mercian Corp filed Critical Mercian Corp
Publication of NO20052568D0 publication Critical patent/NO20052568D0/no
Publication of NO20052568L publication Critical patent/NO20052568L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/162—Heterorings having oxygen atoms as the only ring heteroatoms, e.g. Lasalocid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO20052568A 2002-11-29 2005-05-27 Fremgangsmate for fremstilling av makrolidforbindelse NO20052568L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002346796 2002-11-29
PCT/JP2003/015170 WO2004050890A1 (ja) 2002-11-29 2003-11-27 マクロライド系化合物の製造方法

Publications (2)

Publication Number Publication Date
NO20052568D0 NO20052568D0 (no) 2005-05-27
NO20052568L true NO20052568L (no) 2005-06-29

Family

ID=32462862

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052568A NO20052568L (no) 2002-11-29 2005-05-27 Fremgangsmate for fremstilling av makrolidforbindelse

Country Status (13)

Country Link
US (1) US7745198B2 (ja)
EP (1) EP1580278A4 (ja)
JP (1) JP4439401B2 (ja)
KR (1) KR20050086873A (ja)
CN (1) CN1717493A (ja)
AU (1) AU2003284469B2 (ja)
BR (1) BR0316746A (ja)
CA (1) CA2507641A1 (ja)
MX (1) MXPA05005672A (ja)
NO (1) NO20052568L (ja)
NZ (1) NZ540103A (ja)
RU (1) RU2330069C2 (ja)
WO (1) WO2004050890A1 (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI334866B (en) * 2002-05-29 2010-12-21 Mercian Corp Novel physiologically active substances
US7932083B2 (en) 2003-11-27 2011-04-26 Mercian Corporation DNA participating in hydroxylation of macrolide compound
US8008049B2 (en) 2004-07-20 2011-08-30 Eisai R&D Management Co., Ltd. DNA coding for polypeptide participating in biosynthesis of pladienolide
TW200716744A (en) * 2005-05-26 2007-05-01 Eisai R&D Man Co Ltd Genetically modified microorganism and process for production of macrolide compound using the microorganism
CN102010403A (zh) * 2005-10-13 2011-04-13 卫材R&D管理有限公司 普拉二烯内酯b和普拉二烯内酯d的全合成
EP2052723A4 (en) * 2006-08-14 2010-07-28 Eisai R&D Man Co Ltd STABLE LYOPHILIZED PREPARATION
CN101616912A (zh) * 2007-01-29 2009-12-30 卫材R&D管理有限公司 大环内酯系化合物的固体及其制造方法及其药物组合物
CA3130061A1 (en) 2013-04-04 2014-10-09 President And Fellows Of Harvard College Macrolides and methods of their preparation and use
KR102146726B1 (ko) 2014-05-15 2020-08-21 에자이 알앤드디 매니지먼트 가부시키가이샤 플라디에놀리드 피리딘 화합물 및 사용 방법
JP2017531663A (ja) * 2014-10-08 2017-10-26 プレジデント アンド フェローズ オブ ハーバード カレッジ １４員ケトライドならびにそれらの調製および使用の方法
CA2980315A1 (en) 2015-03-25 2016-09-29 President And Fellows Of Harvard College Macrolides with modified desosamine sugars and uses thereof
WO2017040526A2 (en) 2015-09-01 2017-03-09 Eisai R&D Management Co., Ltd. Splice variants associated with neomorphic sf3b1 mutants
BR112018009995A2 (pt) 2015-11-18 2018-11-21 Eisai R&D Man Co Ltd forma cristalina, composição farmacêutica, método para tratamento de câncer, e, uso de uma forma cristalina
RU2019132208A (ru) 2017-03-15 2021-04-15 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Мутации сплайсингосомы и их применения
EP3703755A1 (en) 2017-10-31 2020-09-09 Eisai R&D Management Co., Ltd. Combination comprising at least one spliceosome modulator and at least one inhibitor chosen from bcl2 inhibitors, bcl2/bclxl inhibitors, and bclxl inhibitors and methods of use
CA3096400A1 (en) 2018-04-09 2019-10-17 Eisai R&D Management Co., Ltd. Certain pladienolide compounds and methods of use
UA127808C2 (uk) 2018-04-12 2024-01-10 ЕйСей РендД МЕНЕДЖМЕНТ КО., ЛТД. Похідна пладієноліду (варіанти) як засіб, що здійснює цілеспрямований вплив на сплайсосому, для лікування раку
CN112367996A (zh) 2018-06-01 2021-02-12 卫材R&D管理有限公司 使用剪接调节剂的方法
US20240043928A1 (en) 2020-11-04 2024-02-08 Eisai R&D Management Co., Ltd. Biomarkers for myelodysplastic syndrome (mds) and methods of using the same
CN114478257A (zh) * 2021-12-29 2022-05-13 福建省山河药业有限公司 一种抗肿瘤霉菌酸类化合物及其制备方法、应用
WO2023131866A1 (en) 2022-01-05 2023-07-13 Eisai R&D Management Co., Ltd. Biomarkers for myelodysplastic syndrome (mds) and methods of using the same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04352783A (ja) 1991-05-27 1992-12-07 Taisho Pharmaceut Co Ltd １２員環マクロライド系化合物
JP2003501423A (ja) 1999-06-03 2003-01-14 アメリカ合衆国 マイコラクトンおよび関連化合物、組成物、ならびに使用方法
WO2002012533A2 (en) 2000-08-03 2002-02-14 Kosan Biosciences, Inc. Fermentation and purification of mycolactones
TWI311558B (en) * 2001-02-01 2009-07-01 Mercian Corporatio Novel physiologically active substance
TWI233361B (en) 2001-04-13 2005-06-01 Gen Hospital Corp Methods of preventing UVB-induced skin damage
TWI334866B (en) * 2002-05-29 2010-12-21 Mercian Corp Novel physiologically active substances
WO2004011661A1 (ja) * 2002-07-31 2004-02-05 Mercian Corporation 新規生理活性物質
CN102010403A (zh) 2005-10-13 2011-04-13 卫材R&D管理有限公司 普拉二烯内酯b和普拉二烯内酯d的全合成

Also Published As

Publication number Publication date
AU2003284469A1 (en) 2004-06-23
US20060141589A1 (en) 2006-06-29
NO20052568D0 (no) 2005-05-27
NZ540103A (en) 2007-05-31
JP4439401B2 (ja) 2010-03-24
MXPA05005672A (es) 2005-08-16
CN1717493A (zh) 2006-01-04
CA2507641A1 (en) 2004-06-17
JPWO2004050890A1 (ja) 2006-03-30
WO2004050890A1 (ja) 2004-06-17
BR0316746A (pt) 2005-10-18
US7745198B2 (en) 2010-06-29
KR20050086873A (ko) 2005-08-30
EP1580278A4 (en) 2010-08-25
RU2005120390A (ru) 2006-01-27
EP1580278A1 (en) 2005-09-28
AU2003284469B2 (en) 2008-02-21
RU2330069C2 (ru) 2008-07-27

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