NO20052568D0 - Fremgangsmate for fremstilling av makrolidforbindelse - Google Patents
Fremgangsmate for fremstilling av makrolidforbindelseInfo
- Publication number
- NO20052568D0 NO20052568D0 NO20052568A NO20052568A NO20052568D0 NO 20052568 D0 NO20052568 D0 NO 20052568D0 NO 20052568 A NO20052568 A NO 20052568A NO 20052568 A NO20052568 A NO 20052568A NO 20052568 D0 NO20052568 D0 NO 20052568D0
- Authority
- NO
- Norway
- Prior art keywords
- macrolide compound
- preparing macrolide
- preparing
- compound
- macrolide
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003120 macrolide antibiotic agent Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
- C12P17/162—Heterorings having oxygen atoms as the only ring heteroatoms, e.g. Lasalocid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002346796 | 2002-11-29 | ||
PCT/JP2003/015170 WO2004050890A1 (ja) | 2002-11-29 | 2003-11-27 | マクロライド系化合物の製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20052568D0 true NO20052568D0 (no) | 2005-05-27 |
NO20052568L NO20052568L (no) | 2005-06-29 |
Family
ID=32462862
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20052568A NO20052568L (no) | 2002-11-29 | 2005-05-27 | Fremgangsmate for fremstilling av makrolidforbindelse |
Country Status (13)
Country | Link |
---|---|
US (1) | US7745198B2 (no) |
EP (1) | EP1580278A4 (no) |
JP (1) | JP4439401B2 (no) |
KR (1) | KR20050086873A (no) |
CN (1) | CN1717493A (no) |
AU (1) | AU2003284469B2 (no) |
BR (1) | BR0316746A (no) |
CA (1) | CA2507641A1 (no) |
MX (1) | MXPA05005672A (no) |
NO (1) | NO20052568L (no) |
NZ (1) | NZ540103A (no) |
RU (1) | RU2330069C2 (no) |
WO (1) | WO2004050890A1 (no) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI334866B (en) * | 2002-05-29 | 2010-12-21 | Mercian Corp | Novel physiologically active substances |
CA2546614A1 (en) | 2003-11-27 | 2005-06-09 | Mercian Corporation | Dna participating in hydroxylation of macrolide compound |
AU2005265443B2 (en) * | 2004-07-20 | 2008-09-04 | Eisai R & D Management Co., Ltd | DNA coding for polypeptide participating in biosynthesis of pladienolide |
TW200716744A (en) * | 2005-05-26 | 2007-05-01 | Eisai R&D Man Co Ltd | Genetically modified microorganism and process for production of macrolide compound using the microorganism |
CN101282967B (zh) * | 2005-10-13 | 2011-01-26 | 卫材R&D管理有限公司 | 普拉二烯内酯b和普拉二烯内酯d的全合成 |
US20090325978A1 (en) * | 2006-08-14 | 2009-12-31 | Katsumi Onai | Stable lyophilized preparation |
US7790887B2 (en) * | 2007-01-29 | 2010-09-07 | Eisai R&D Management Co., Ltd. | Macrolide compound in solid form, process for preparation thereof, and pharmaceutical composition containing the same |
MX2015014026A (es) | 2013-04-04 | 2016-08-03 | Harvard College | Macrolidos y metodos para su preparacion y uso. |
SI3143016T1 (sl) | 2014-05-15 | 2019-04-30 | Eisai R&D Management Co., Ltd. | Spojine pladienolid piridina in postopki uporabe |
JP2017531663A (ja) | 2014-10-08 | 2017-10-26 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 14員ケトライドならびにそれらの調製および使用の方法 |
JP2018509452A (ja) | 2015-03-25 | 2018-04-05 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 修飾デソサミン糖をもつマクロライドおよびその使用 |
US10889866B2 (en) | 2015-09-01 | 2021-01-12 | Eisai R&D Management Co., Ltd. | Splice variants associated with neomorphic SF3B1 mutants |
RU2021102393A (ru) | 2015-11-18 | 2021-03-17 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Твердые формы пладиенолидпиридиновых соединений и способы их применения |
WO2018170129A1 (en) | 2017-03-15 | 2018-09-20 | Eisai Co., Ltd | Spliceosome mutations and uses thereof |
KR20200083532A (ko) | 2017-10-31 | 2020-07-08 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 적어도 1종의 스플라이세오솜 조정제, 및 bcl2 억제제, bcl2/bclxl 억제제 및 bclxl 억제제로부터 선택된 적어도 1종의 억제제를 포함하는 조합물 및 사용 방법 |
BR112020020792A2 (pt) | 2018-04-09 | 2021-01-12 | Eisai R&D Management Co., Ltd. | Certos compostos de pladienolida e métodos de uso |
SG11202009907XA (en) | 2018-04-12 | 2020-11-27 | Eisai R&D Man Co Ltd | Pladienolide derivatives as spliceosome targeting agents for treating cancer |
EP3801523A2 (en) | 2018-06-01 | 2021-04-14 | Eisai R&D Management Co., Ltd. | Methods of using splicing modulators |
TW202233187A (zh) | 2020-11-04 | 2022-09-01 | 日商衛材R&D企管股份有限公司 | 骨髓發育不良症候群(mds)之生物標記物及其使用方法 |
CN114478257A (zh) * | 2021-12-29 | 2022-05-13 | 福建省山河药业有限公司 | 一种抗肿瘤霉菌酸类化合物及其制备方法、应用 |
WO2023131866A1 (en) | 2022-01-05 | 2023-07-13 | Eisai R&D Management Co., Ltd. | Biomarkers for myelodysplastic syndrome (mds) and methods of using the same |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04352783A (ja) | 1991-05-27 | 1992-12-07 | Taisho Pharmaceut Co Ltd | 12員環マクロライド系化合物 |
EP1192147A1 (en) | 1999-06-03 | 2002-04-03 | THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Mycolactone and related compounds, compositions and methods of use |
US6562602B2 (en) | 2000-08-03 | 2003-05-13 | Kosan Biosciences, Inc. | Fermentation and purification of mycolactones |
TWI311558B (en) * | 2001-02-01 | 2009-07-01 | Mercian Corporatio | Novel physiologically active substance |
TWI233361B (en) * | 2001-04-13 | 2005-06-01 | Gen Hospital Corp | Methods of preventing UVB-induced skin damage |
TWI334866B (en) | 2002-05-29 | 2010-12-21 | Mercian Corp | Novel physiologically active substances |
CN1671856B (zh) * | 2002-07-31 | 2010-05-12 | 卫材R&D管理株式会社 | 生理活性物质 |
CN101282967B (zh) * | 2005-10-13 | 2011-01-26 | 卫材R&D管理有限公司 | 普拉二烯内酯b和普拉二烯内酯d的全合成 |
-
2003
- 2003-11-27 NZ NZ540103A patent/NZ540103A/en unknown
- 2003-11-27 RU RU2005120390/13A patent/RU2330069C2/ru not_active IP Right Cessation
- 2003-11-27 CN CNA2003801044327A patent/CN1717493A/zh active Pending
- 2003-11-27 CA CA002507641A patent/CA2507641A1/en not_active Abandoned
- 2003-11-27 WO PCT/JP2003/015170 patent/WO2004050890A1/ja active Application Filing
- 2003-11-27 EP EP03775924A patent/EP1580278A4/en not_active Withdrawn
- 2003-11-27 MX MXPA05005672A patent/MXPA05005672A/es active IP Right Grant
- 2003-11-27 KR KR1020057009524A patent/KR20050086873A/ko not_active Application Discontinuation
- 2003-11-27 BR BR0316746-1A patent/BR0316746A/pt not_active IP Right Cessation
- 2003-11-27 US US10/532,412 patent/US7745198B2/en not_active Expired - Fee Related
- 2003-11-27 AU AU2003284469A patent/AU2003284469B2/en not_active Ceased
- 2003-11-27 JP JP2004556846A patent/JP4439401B2/ja not_active Expired - Fee Related
-
2005
- 2005-05-27 NO NO20052568A patent/NO20052568L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20050086873A (ko) | 2005-08-30 |
RU2005120390A (ru) | 2006-01-27 |
NO20052568L (no) | 2005-06-29 |
CN1717493A (zh) | 2006-01-04 |
CA2507641A1 (en) | 2004-06-17 |
WO2004050890A1 (ja) | 2004-06-17 |
EP1580278A1 (en) | 2005-09-28 |
MXPA05005672A (es) | 2005-08-16 |
RU2330069C2 (ru) | 2008-07-27 |
AU2003284469B2 (en) | 2008-02-21 |
AU2003284469A1 (en) | 2004-06-23 |
NZ540103A (en) | 2007-05-31 |
JP4439401B2 (ja) | 2010-03-24 |
JPWO2004050890A1 (ja) | 2006-03-30 |
BR0316746A (pt) | 2005-10-18 |
EP1580278A4 (en) | 2010-08-25 |
US20060141589A1 (en) | 2006-06-29 |
US7745198B2 (en) | 2010-06-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |