NO20044964L - Flytende preparat som omfatter camptothecinderivat og farmasoytisk preparat som kan fremstilles ved a lyofilisere preparatet - Google Patents
Flytende preparat som omfatter camptothecinderivat og farmasoytisk preparat som kan fremstilles ved a lyofilisere preparatetInfo
- Publication number
- NO20044964L NO20044964L NO20044964A NO20044964A NO20044964L NO 20044964 L NO20044964 L NO 20044964L NO 20044964 A NO20044964 A NO 20044964A NO 20044964 A NO20044964 A NO 20044964A NO 20044964 L NO20044964 L NO 20044964L
- Authority
- NO
- Norway
- Prior art keywords
- prepared
- pharmaceutical composition
- preparation
- camptothecin derivative
- lyophilizing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Foreliggende oppfinnelsen vedrører et stabilt flytende preparat som omfatter et camptothecinderivat som er fremstilt ved å binde sammen en forbindelse med formel [I] eller et farmasøytisk akseptabelt salt derav, som er justert til pH 5-8, eller et stabilt farmasøytisk preparat som er fremstilt ved å lyofilisere nevnte fiytende preparat. Foreliggende oppfinnelsen vedrører et stabilt flytende preparat som omfatter et camptothecinderivat som er fremstilt ved å binde sammen en forbindelse med formel [I], X' ¿Alk-0- der r' er en substituert eller ikke- subsitituert lavere alkylgmppe, X' er en gmppe med formel -NHR2 (R2 er et hydrogenatom eller en lavere alkylgmppe) eller en hydroksygruppe, og Alk er en rettkjedet eller forgrenet alkylengmppe som eventuelt er avbmtt av et oksygenatom, og et polysakkarid som har karboksylgrupper, via en aminosyre eller et peptid, eller et farmasøytisk akseptabelt salt derav, som er Justert til pH-S-8, eller et stabilt farmasøytisk preparat som er fiemstilt ved & lyofilisere nevnte flytende preparat.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002112864 | 2002-04-16 | ||
PCT/JP2003/004745 WO2003086471A2 (en) | 2002-04-16 | 2003-04-15 | Lyophilized and liquid preparations comprising a polysaccharide derivative of camptothecin |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20044964L true NO20044964L (no) | 2004-11-15 |
Family
ID=29243336
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20044964A NO20044964L (no) | 2002-04-16 | 2004-11-15 | Flytende preparat som omfatter camptothecinderivat og farmasoytisk preparat som kan fremstilles ved a lyofilisere preparatet |
Country Status (21)
Country | Link |
---|---|
US (1) | US20050215485A1 (no) |
EP (1) | EP1501549A2 (no) |
JP (1) | JP3927954B2 (no) |
KR (1) | KR100700963B1 (no) |
CN (1) | CN100544769C (no) |
AR (1) | AR039272A1 (no) |
AU (1) | AU2003223120B2 (no) |
BR (1) | BR0309283A (no) |
CA (1) | CA2480425A1 (no) |
HR (1) | HRP20040894A2 (no) |
ME (1) | MEP31308A (no) |
MX (1) | MXPA04010178A (no) |
MY (1) | MY136696A (no) |
NO (1) | NO20044964L (no) |
PL (1) | PL371677A1 (no) |
RS (1) | RS91204A (no) |
RU (1) | RU2315623C2 (no) |
TW (1) | TW200306314A (no) |
UA (1) | UA77295C2 (no) |
WO (1) | WO2003086471A2 (no) |
ZA (1) | ZA200408008B (no) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE602005024923D1 (de) * | 2004-02-13 | 2011-01-05 | Yakult Honsha Kk | Wässrige lösung mit einem camptothecin |
CN1946421B (zh) | 2004-04-27 | 2013-07-17 | 威尔斯达特生物制剂公司 | 使用病毒和喜树碱进行的癌症治疗 |
RU2435586C2 (ru) | 2005-07-14 | 2011-12-10 | Веллстат Байолоджикс Корпорейшн | Лечение рака с применением вирусов, фторпиримидинов и камптотецинов |
JP2007260275A (ja) * | 2006-03-29 | 2007-10-11 | Transcutaneous Technologies Inc | イオントフォレーシス装置及びイオントフォレーシス投与用組成物 |
WO2010151544A1 (en) | 2009-06-22 | 2010-12-29 | Wyeth Llc | Immunogenic compositions of staphylococcus aureus antigens |
JP2012530785A (ja) | 2009-06-22 | 2012-12-06 | ワイス・エルエルシー | 組成物および黄色ブドウ球菌(Staphylococcusaureus)血清型5および8莢膜多糖コンジュゲート免疫原性組成物を調製するための方法 |
CN102764260B (zh) * | 2011-04-30 | 2014-07-30 | 正大天晴药业集团股份有限公司 | 一种喜树碱衍生物的药物组合物及其制备方法 |
WO2013011598A1 (ja) * | 2011-07-15 | 2013-01-24 | コニカミノルタホールディングス株式会社 | 溶解助剤を利用したリポソーム含有製剤およびその製造方法 |
AU2015369185B2 (en) | 2014-12-26 | 2020-10-22 | Nippon Kayaku Kabushiki Kaisha | Pharmaceutical preparation of camptothecin-containing polymer derivative |
KR20180039628A (ko) | 2015-09-03 | 2018-04-18 | 니폰 가야꾸 가부시끼가이샤 | 캄프토테신류 고분자 유도체를 함유하는 의약 조성물 |
AU2016326747A1 (en) | 2015-09-25 | 2018-03-01 | Zy Therapeutics Inc. | Drug formulation based on particulates comprising polysaccharide-vitamin conjugate |
CN108697806A (zh) * | 2016-03-01 | 2018-10-23 | 日本化药株式会社 | 含有喜树碱类高分子衍生物的药物制剂 |
CN109481691A (zh) * | 2018-11-20 | 2019-03-19 | 珠海天香苑生物科技发展股份有限公司 | 吉西他滨-羧甲基多糖共轭物、制备方法及其用途 |
AU2022396967A1 (en) * | 2021-11-26 | 2024-06-13 | Astellas Pharma Inc. | Indocyanine compound-containing solid pharmaceutical composition |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5340817A (en) * | 1987-04-14 | 1994-08-23 | Research Triangle Institute | Method of treating tumors with anti-tumor effective camptothecin compounds |
SG50747A1 (en) * | 1995-08-02 | 1998-07-20 | Tanabe Seiyaku Co | Comptothecin derivatives |
TW527183B (en) * | 1996-06-06 | 2003-04-11 | Daiichi Seiyaku Co | Drug complex |
US6288072B1 (en) * | 1999-12-29 | 2001-09-11 | Monroe E. Wall | Camptothecin β-alanine esters with topoisomerase I inhibition |
AR030207A1 (es) * | 2000-04-07 | 2003-08-13 | Daiichi Seiyaku Co | Composicion farmaceutica que contiene un derivado de camptotecina y procedimiento de preparacion de la misma |
AU2001271037A1 (en) * | 2000-07-13 | 2002-01-30 | Daiichi Pharmaceutical Co., Ltd. | Pharmaceutical compositions containing dds compounds |
TWI313609B (en) * | 2001-08-21 | 2009-08-21 | Mitsubishi Tanabe Pharma Corp | Pharmaceutical composition for inhibiting the metastasis or preventing the recurrence of malignant tumor |
-
2003
- 2003-04-01 TW TW092107354A patent/TW200306314A/zh unknown
- 2003-04-09 AR ARP030101238A patent/AR039272A1/es unknown
- 2003-04-11 MY MYPI20031367A patent/MY136696A/en unknown
- 2003-04-15 AU AU2003223120A patent/AU2003223120B2/en not_active Ceased
- 2003-04-15 PL PL03371677A patent/PL371677A1/xx not_active Application Discontinuation
- 2003-04-15 BR BR0309283-6A patent/BR0309283A/pt not_active IP Right Cessation
- 2003-04-15 JP JP2003587152A patent/JP3927954B2/ja not_active Expired - Fee Related
- 2003-04-15 MX MXPA04010178A patent/MXPA04010178A/es active IP Right Grant
- 2003-04-15 CA CA002480425A patent/CA2480425A1/en not_active Abandoned
- 2003-04-15 US US10/509,912 patent/US20050215485A1/en not_active Abandoned
- 2003-04-15 WO PCT/JP2003/004745 patent/WO2003086471A2/en active Application Filing
- 2003-04-15 CN CNB038082292A patent/CN100544769C/zh not_active Expired - Fee Related
- 2003-04-15 ME MEP-313/08A patent/MEP31308A/xx unknown
- 2003-04-15 RS YU91204A patent/RS91204A/sr unknown
- 2003-04-15 RU RU2004133349/15A patent/RU2315623C2/ru not_active IP Right Cessation
- 2003-04-15 KR KR1020047016514A patent/KR100700963B1/ko not_active IP Right Cessation
- 2003-04-15 UA UA20041109367A patent/UA77295C2/uk unknown
- 2003-04-15 EP EP03719110A patent/EP1501549A2/en not_active Withdrawn
-
2004
- 2004-09-29 HR HR20040894A patent/HRP20040894A2/xx not_active Application Discontinuation
- 2004-10-05 ZA ZA200408008A patent/ZA200408008B/en unknown
- 2004-11-15 NO NO20044964A patent/NO20044964L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
MY136696A (en) | 2008-11-28 |
CA2480425A1 (en) | 2003-10-23 |
RU2004133349A (ru) | 2005-05-27 |
AU2003223120A1 (en) | 2003-10-27 |
CN1646172A (zh) | 2005-07-27 |
AR039272A1 (es) | 2005-02-16 |
BR0309283A (pt) | 2005-02-15 |
JP3927954B2 (ja) | 2007-06-13 |
MEP31308A (en) | 2010-10-10 |
RU2315623C2 (ru) | 2008-01-27 |
KR20050000516A (ko) | 2005-01-05 |
US20050215485A1 (en) | 2005-09-29 |
AU2003223120B2 (en) | 2006-10-05 |
PL371677A1 (en) | 2005-06-27 |
EP1501549A2 (en) | 2005-02-02 |
TW200306314A (en) | 2003-11-16 |
ZA200408008B (en) | 2005-06-13 |
KR100700963B1 (ko) | 2007-03-28 |
AU2003223120A2 (en) | 2003-10-27 |
RS91204A (en) | 2006-12-15 |
JP2005523329A (ja) | 2005-08-04 |
WO2003086471A3 (en) | 2004-04-15 |
WO2003086471A2 (en) | 2003-10-23 |
MXPA04010178A (es) | 2005-06-08 |
CN100544769C (zh) | 2009-09-30 |
HRP20040894A2 (en) | 2005-10-31 |
UA77295C2 (en) | 2006-11-15 |
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Legal Events
Date | Code | Title | Description |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |