NO20012701L - Aryl- og heterosyklylsubstituerte pyrimidinderivater som antikoagulanter - Google Patents

Aryl- og heterosyklylsubstituerte pyrimidinderivater som antikoagulanter

Info

Publication number
NO20012701L
NO20012701L NO20012701A NO20012701A NO20012701L NO 20012701 L NO20012701 L NO 20012701L NO 20012701 A NO20012701 A NO 20012701A NO 20012701 A NO20012701 A NO 20012701A NO 20012701 L NO20012701 L NO 20012701L
Authority
NO
Norway
Prior art keywords
anticoagulants
heterocyclyl
aryl
pyrimidine derivatives
substituted pyrimidine
Prior art date
Application number
NO20012701A
Other languages
English (en)
Norwegian (no)
Other versions
NO20012701D0 (no
Inventor
David D Davey
Gary B Phillips
Original Assignee
Berlex Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berlex Lab filed Critical Berlex Lab
Publication of NO20012701D0 publication Critical patent/NO20012701D0/no
Publication of NO20012701L publication Critical patent/NO20012701L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NO20012701A 1998-12-04 2001-06-01 Aryl- og heterosyklylsubstituerte pyrimidinderivater som antikoagulanter NO20012701L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/205,498 US6127376A (en) 1998-12-04 1998-12-04 Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants
PCT/US1999/028537 WO2000033844A1 (en) 1998-12-04 1999-12-03 Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants

Publications (2)

Publication Number Publication Date
NO20012701D0 NO20012701D0 (no) 2001-06-01
NO20012701L true NO20012701L (no) 2001-07-25

Family

ID=22762435

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012701A NO20012701L (no) 1998-12-04 2001-06-01 Aryl- og heterosyklylsubstituerte pyrimidinderivater som antikoagulanter

Country Status (26)

Country Link
US (2) US6127376A (ro)
EP (1) EP1135131A4 (ro)
JP (1) JP2002531506A (ro)
KR (1) KR20010093799A (ro)
CN (1) CN1329491A (ro)
AU (1) AU760370B2 (ro)
BG (1) BG105557A (ro)
BR (1) BR9915938A (ro)
CA (1) CA2354040A1 (ro)
CZ (1) CZ20011932A3 (ro)
EE (1) EE200100298A (ro)
HR (1) HRP20010499A2 (ro)
HU (1) HUP0104508A3 (ro)
IL (2) IL143347A0 (ro)
LT (1) LT4912B (ro)
LV (1) LV12783B (ro)
MX (1) MXPA01005656A (ro)
NO (1) NO20012701L (ro)
NZ (1) NZ512104A (ro)
PL (1) PL348034A1 (ro)
RO (1) RO120971B1 (ro)
RU (1) RU2001118466A (ro)
SI (1) SI20637A (ro)
SK (1) SK7632001A3 (ro)
WO (1) WO2000033844A1 (ro)
ZA (1) ZA200104235B (ro)

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EP2637502B1 (en) 2010-11-10 2018-01-10 Celgene CAR LLC Mutant-selective egfr inhibitors and uses thereof
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US9359308B2 (en) 2011-11-23 2016-06-07 Portola Pharmaceuticals, Inc. Pyrazine kinase inhibitors
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Also Published As

Publication number Publication date
LV12783B (en) 2002-10-20
NZ512104A (en) 2003-10-31
CA2354040A1 (en) 2000-06-15
LT2001061A (en) 2001-12-27
LT4912B (lt) 2002-04-25
US6372751B1 (en) 2002-04-16
HUP0104508A3 (en) 2002-07-29
IL143347A (en) 2006-12-10
SK7632001A3 (en) 2001-12-03
CN1329491A (zh) 2002-01-02
BG105557A (en) 2001-12-29
HRP20010499A2 (en) 2003-04-30
WO2000033844A1 (en) 2000-06-15
MXPA01005656A (es) 2002-04-24
RU2001118466A (ru) 2003-04-20
CZ20011932A3 (cs) 2001-10-17
LV12783A (en) 2002-01-20
RO120971B1 (ro) 2006-10-30
PL348034A1 (en) 2002-05-06
ZA200104235B (en) 2002-08-23
NO20012701D0 (no) 2001-06-01
EP1135131A4 (en) 2002-01-02
US6127376A (en) 2000-10-03
SI20637A (sl) 2002-02-28
HUP0104508A2 (hu) 2002-05-29
EP1135131A1 (en) 2001-09-26
AU3107500A (en) 2000-06-26
AU760370B2 (en) 2003-05-15
IL143347A0 (en) 2002-04-21
BR9915938A (pt) 2001-08-21
KR20010093799A (ko) 2001-10-29
JP2002531506A (ja) 2002-09-24
EE200100298A (et) 2002-12-16

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