NO20006600L - Ikke-peptidylinhibitorer av VLA-4-avhengig cellebinding nyttig for behandling av inflammatoriske, autoimmune og respiratoriske sykdommer - Google Patents

Ikke-peptidylinhibitorer av VLA-4-avhengig cellebinding nyttig for behandling av inflammatoriske, autoimmune og respiratoriske sykdommer

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Publication number
NO20006600L
NO20006600L NO20006600A NO20006600A NO20006600L NO 20006600 L NO20006600 L NO 20006600L NO 20006600 A NO20006600 A NO 20006600A NO 20006600 A NO20006600 A NO 20006600A NO 20006600 L NO20006600 L NO 20006600L
Authority
NO
Norway
Prior art keywords
vla
autoimmune
inflammatory
treatment
cell binding
Prior art date
Application number
NO20006600A
Other languages
English (en)
Norwegian (no)
Other versions
NO20006600D0 (no
Inventor
Allen Jacob Duplantier
Anthony John Milici
Louis Stanley Chupak
Original Assignee
Pfizer Prod Inc
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Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20006600D0 publication Critical patent/NO20006600D0/no
Publication of NO20006600L publication Critical patent/NO20006600L/no

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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
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NO20006600A 1998-06-30 2000-12-22 Ikke-peptidylinhibitorer av VLA-4-avhengig cellebinding nyttig for behandling av inflammatoriske, autoimmune og respiratoriske sykdommer NO20006600L (no)

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PCT/IB1999/000973 WO2000000477A1 (en) 1998-06-30 1999-05-31 Non-peptidyl inhibitors of vla-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases

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US6756378B2 (en) * 1999-06-30 2004-06-29 Pharmacopeia Drug Discovery, Inc. VLA-4 inhibitor compounds
CN1391473A (zh) * 1999-06-30 2003-01-15 第一制药株式会社 Vla－4抑制剂化合物
AP2002002565A0 (en) 1999-12-28 2002-06-30 Pfizer Prod Inc Non-peptidyl inhibitors of VLA-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases.
WO2001056994A1 (en) * 2000-02-04 2001-08-09 Biogen, Inc. Integrin antagonists
AU2001268607A1 (en) 2000-06-21 2002-01-02 Bristol-Myers Squibb Company Piperidine amides as modulators of chemokine receptor activity
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GB2367816A (en) * 2000-10-09 2002-04-17 Bayer Ag Urea- and thiourea-containing derivatives of beta-amino acids
EP1346982B1 (en) 2000-12-28 2011-09-14 Daiichi Pharmaceutical Co., Ltd. Vla-4 inhibitors
DE10111877A1 (de) * 2001-03-10 2002-09-12 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
CA2446136C (en) 2001-05-03 2011-07-05 Galileo Pharmaceuticals, Inc. Pyruvate derivatives
DK1392306T3 (da) * 2001-06-06 2008-05-19 Aventis Pharma Ltd Substituerede tetrahydroisoquinoliner til anvendelse i behandlingen af inflammatoriske sygdomme
GB2377933A (en) 2001-07-06 2003-01-29 Bayer Ag Succinic acid derivatives useful as integrin antagonists
DE10137595A1 (de) 2001-08-01 2003-02-13 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung und ihre Verwendung
WO2003024401A2 (en) * 2001-09-18 2003-03-27 Bristol-Myers Squibb Company Piperizinones as modulators of chemokine receptor activity
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JP3676677B2 (ja) 2005-07-27
NO20006600D0 (no) 2000-12-22
IL139584A0 (en) 2002-02-10
WO2000000477A1 (en) 2000-01-06
AP9901561A0 (en) 1999-06-30
AU3841699A (en) 2000-01-17
HRP20000917A2 (en) 2002-02-28
EA200001238A1 (ru) 2001-08-27
EA004792B1 (ru) 2004-08-26
BG105190A (en) 2001-12-29
US6355662B1 (en) 2002-03-12
CA2336625A1 (en) 2000-01-06
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HUP0102477A2 (hu) 2002-05-29
US6306887B1 (en) 2001-10-23
ATE311371T1 (de) 2005-12-15
ID27414A (id) 2001-04-05
OA11577A (en) 2004-07-26
TNSN99110A1 (fr) 2005-11-10
KR20010083081A (ko) 2001-08-31
HN1999000099A (es) 1999-11-11
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AR015312A1 (es) 2001-04-18
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YU77600A (sh) 2004-03-12
JP2002519344A (ja) 2002-07-02
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PA8477001A1 (es) 2000-05-24
CO5320599A1 (es) 2003-09-30
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