NO20004980L - Partikulære varer av aktive ingredienser for den pulmonale anvendelsen - Google Patents
Partikulære varer av aktive ingredienser for den pulmonale anvendelsenInfo
- Publication number
- NO20004980L NO20004980L NO20004980A NO20004980A NO20004980L NO 20004980 L NO20004980 L NO 20004980L NO 20004980 A NO20004980 A NO 20004980A NO 20004980 A NO20004980 A NO 20004980A NO 20004980 L NO20004980 L NO 20004980L
- Authority
- NO
- Norway
- Prior art keywords
- active ingredients
- particulate
- pulmonary use
- particulate articles
- pulmonary
- Prior art date
Links
- 230000002685 pulmonary effect Effects 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 title 1
- 229920001503 Glucan Polymers 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Compounds Of Unknown Constitution (AREA)
- Saccharide Compounds (AREA)
Abstract
Oppfinnelsen angår tilveiebringelse av en partikulær virkestoffbærer og dens farmasøytiske sammensetning med depotvirkning for pulmonal applikasjon. Den tønformulerbare biokompatible, partikulære virkestoffbæreren fremstilles helt eller til dels av lineære vannuoppløselige polysakkarider, fortrinnsvis poly(l,4-a-D-glukan), med homogen enhetlig størrelse fra fortrinnsvis biotransformatorisk fremstilling med evnen til å kluster- og/eller agglomeratdannelse. De derav resulterende fordeler benyttes fortrinnsvis i rammen av den tørre pulverinhaleringen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19816085 | 1998-04-09 | ||
PCT/EP1999/002385 WO1999052506A1 (de) | 1998-04-09 | 1999-04-08 | Partikulärer wirkstoffträger für die pulmonale applikation |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20004980D0 NO20004980D0 (no) | 2000-10-03 |
NO20004980L true NO20004980L (no) | 2000-12-08 |
Family
ID=7864224
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20004980A NO20004980L (no) | 1998-04-09 | 2000-10-03 | Partikulære varer av aktive ingredienser for den pulmonale anvendelsen |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP1069889B1 (no) |
JP (1) | JP2002511399A (no) |
KR (1) | KR20010034755A (no) |
CN (1) | CN1423553A (no) |
AT (1) | ATE270097T1 (no) |
AU (1) | AU3421099A (no) |
CA (1) | CA2340340A1 (no) |
DE (1) | DE59909854D1 (no) |
HU (1) | HUP0101912A2 (no) |
NO (1) | NO20004980L (no) |
PL (1) | PL343342A1 (no) |
WO (1) | WO1999052506A1 (no) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19847593A1 (de) * | 1998-10-15 | 2000-04-20 | Aventis Res & Tech Gmbh & Co | Zusammensetzung für die parenterale Applikation von Wirkstoffen |
PT1808438E (pt) | 1999-06-29 | 2015-01-14 | Mannkind Corp | Purificação e estabilização de péptidos e proteínas em agentes farmacêuticos |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
ATE385193T1 (de) | 2002-03-20 | 2008-02-15 | Mannkind Corp | Inhalationsgerät |
US20080090753A1 (en) | 2004-03-12 | 2008-04-17 | Biodel, Inc. | Rapid Acting Injectable Insulin Compositions |
AU2005277208B2 (en) | 2004-08-20 | 2011-11-24 | Mannkind Corporation | Catalysis of diketopiperazine synthesis |
DK1791542T3 (en) | 2004-08-23 | 2015-06-15 | Mannkind Corp | Diketopiperazinsalte for pharmaceutical delivery |
BRPI0615819B8 (pt) | 2005-09-14 | 2021-05-25 | Mannkind Corp | processo para preparar uma composição de distribuição de fármaco compreendendo um agente ativo e uma micropartícula fumaril dicetopiperazina cristalina. |
US8084420B2 (en) | 2005-09-29 | 2011-12-27 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
CN101389348A (zh) * | 2006-02-22 | 2009-03-18 | 曼金德公司 | 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法 |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
CA3086027C (en) | 2008-06-13 | 2022-05-17 | Mannkind Corporation | A dry powder inhaler and system for drug delivery |
MX2010014240A (es) | 2008-06-20 | 2011-03-25 | Mankind Corp | Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion. |
TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
US9060927B2 (en) | 2009-03-03 | 2015-06-23 | Biodel Inc. | Insulin formulations for rapid uptake |
DK2405963T3 (da) | 2009-03-11 | 2013-12-16 | Mannkind Corp | Apparat, system og fremgangsmåde til at måle modstand i en inhalator |
US8227409B2 (en) | 2009-06-12 | 2012-07-24 | Mannkind Corporation | Diketopiperazine microparticles with defined isomer contents |
WO2010144789A2 (en) | 2009-06-12 | 2010-12-16 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
KR20130117755A (ko) | 2010-06-21 | 2013-10-28 | 맨카인드 코포레이션 | 건조 분말 약물 운반 시스템 및 방법 |
WO2012135765A2 (en) | 2011-04-01 | 2012-10-04 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
MX2014004983A (es) | 2011-10-24 | 2014-09-22 | Mannkid Corp | Metodos y composiciones para tratar dolor. |
CN104619369B (zh) | 2012-07-12 | 2018-01-30 | 曼金德公司 | 干粉药物输送系统和方法 |
EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
WO2014074797A1 (en) * | 2012-11-09 | 2014-05-15 | Civitas Therapeutics, Inc. | Ultra low density pulmonary powders |
WO2014144895A1 (en) | 2013-03-15 | 2014-09-18 | Mannkind Corporation | Microcrystalline diketopiperazine compositions and methods |
JP6491658B2 (ja) | 2013-07-18 | 2019-03-27 | マンカインド コーポレイション | 熱安定性乾燥粉末医薬組成物及び方法 |
US11446127B2 (en) | 2013-08-05 | 2022-09-20 | Mannkind Corporation | Insufflation apparatus and methods |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
WO2018222581A1 (en) * | 2017-05-29 | 2018-12-06 | Resinnate Therapeutics Llc | Methods and formulations for administering beta glucan |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB937303A (en) * | 1959-01-02 | 1963-09-18 | Benger Lab Ltd | Improvements in and relating to the application of drugs in finely divided condition |
US6428771B1 (en) * | 1995-05-15 | 2002-08-06 | Pharmaceutical Discovery Corporation | Method for drug delivery to the pulmonary system |
GB9606188D0 (en) * | 1996-03-23 | 1996-05-29 | Danbiosyst Uk | Pollysaccharide microspheres for the pulmonary delivery of drugs |
DE19737481A1 (de) * | 1997-08-28 | 1999-03-04 | Hoechst Ag | Sphärische lineare Polysaccharide enthaltende Mikropartikel |
-
1999
- 1999-04-08 AT AT99915750T patent/ATE270097T1/de not_active IP Right Cessation
- 1999-04-08 EP EP99915750A patent/EP1069889B1/de not_active Expired - Lifetime
- 1999-04-08 DE DE59909854T patent/DE59909854D1/de not_active Expired - Lifetime
- 1999-04-08 JP JP2000543116A patent/JP2002511399A/ja active Pending
- 1999-04-08 KR KR1020007011142A patent/KR20010034755A/ko not_active Application Discontinuation
- 1999-04-08 AU AU34210/99A patent/AU3421099A/en not_active Abandoned
- 1999-04-08 CA CA002340340A patent/CA2340340A1/en not_active Abandoned
- 1999-04-08 HU HU0101912A patent/HUP0101912A2/hu unknown
- 1999-04-08 CN CN99806153A patent/CN1423553A/zh active Pending
- 1999-04-08 WO PCT/EP1999/002385 patent/WO1999052506A1/de active IP Right Grant
- 1999-04-08 PL PL99343342A patent/PL343342A1/xx unknown
-
2000
- 2000-10-03 NO NO20004980A patent/NO20004980L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE59909854D1 (de) | 2004-08-05 |
NO20004980D0 (no) | 2000-10-03 |
EP1069889A1 (de) | 2001-01-24 |
WO1999052506A1 (de) | 1999-10-21 |
AU3421099A (en) | 1999-11-01 |
WO1999052506B1 (de) | 1999-11-25 |
HUP0101912A2 (hu) | 2001-10-28 |
JP2002511399A (ja) | 2002-04-16 |
ATE270097T1 (de) | 2004-07-15 |
CN1423553A (zh) | 2003-06-11 |
CA2340340A1 (en) | 1999-10-21 |
KR20010034755A (ko) | 2001-04-25 |
PL343342A1 (en) | 2001-08-13 |
EP1069889B1 (de) | 2004-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |