NO20003111L - Orto-antranilamidderivater som antikoagulanter - Google Patents
Orto-antranilamidderivater som antikoagulanterInfo
- Publication number
- NO20003111L NO20003111L NO20003111A NO20003111A NO20003111L NO 20003111 L NO20003111 L NO 20003111L NO 20003111 A NO20003111 A NO 20003111A NO 20003111 A NO20003111 A NO 20003111A NO 20003111 L NO20003111 L NO 20003111L
- Authority
- NO
- Norway
- Prior art keywords
- anticoagulants
- ortho
- anthranilamide derivatives
- anthranilamide
- derivatives
- Prior art date
Links
- 239000003146 anticoagulant agent Substances 0.000 title abstract 2
- 229940127219 anticoagulant drug Drugs 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 241001620634 Roger Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99428497A | 1997-12-19 | 1997-12-19 | |
| US09/187,459 US6140351A (en) | 1997-12-19 | 1998-11-05 | Ortho-anthranilamide derivatives as anti-coagulants |
| PCT/EP1998/007650 WO1999032477A1 (en) | 1997-12-19 | 1998-11-27 | Ortho-anthranilamide derivatives as anti-coagulants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20003111D0 NO20003111D0 (no) | 2000-06-16 |
| NO20003111L true NO20003111L (no) | 2000-08-18 |
Family
ID=26883056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20003111A NO20003111L (no) | 1997-12-19 | 2000-06-16 | Orto-antranilamidderivater som antikoagulanter |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6498185B1 (xx) |
| EP (1) | EP1040108B1 (xx) |
| JP (1) | JP3811006B2 (xx) |
| CN (1) | CN1143855C (xx) |
| AT (1) | ATE260103T1 (xx) |
| AU (1) | AU751856B2 (xx) |
| CA (1) | CA2315070A1 (xx) |
| DE (1) | DE69821985T2 (xx) |
| DK (1) | DK1040108T3 (xx) |
| ES (1) | ES2215337T3 (xx) |
| HU (1) | HUP0101172A3 (xx) |
| IL (1) | IL135536A0 (xx) |
| NO (1) | NO20003111L (xx) |
| NZ (1) | NZ503809A (xx) |
| PL (1) | PL341044A1 (xx) |
| PT (1) | PT1040108E (xx) |
| RU (1) | RU2226529C2 (xx) |
| SK (1) | SK9432000A3 (xx) |
| WO (1) | WO1999032477A1 (xx) |
Families Citing this family (79)
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|---|---|---|---|---|
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| US6004985A (en) | 1996-10-09 | 1999-12-21 | Berlex Laboratories, Inc. | Thio acid derived monocylic N-heterocyclics as anticoagulants |
| JP2002512633A (ja) | 1997-06-26 | 2002-04-23 | イーライ・リリー・アンド・カンパニー | 抗血栓剤 |
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| IL133625A0 (en) | 1997-06-26 | 2001-04-30 | Lilly Co Eli | Antithrombotic agents |
| US6313151B1 (en) | 1997-06-26 | 2001-11-06 | Eli Lilly And Company | Antithrombotic agents |
| US6291514B1 (en) | 1998-02-09 | 2001-09-18 | 3-Dimensional Pharmaceuticals, Inc. | Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors |
| GB9824579D0 (en) | 1998-11-10 | 1999-01-06 | Novartis Ag | Organic compounds |
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| ATE326453T1 (de) | 1998-12-23 | 2006-06-15 | Lilly Co Eli | Antithrombotische amide |
| JP2002533454A (ja) | 1998-12-23 | 2002-10-08 | イーライ・リリー・アンド・カンパニー | 芳香族アミド類 |
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| CA2375920A1 (en) | 1999-06-14 | 2000-12-21 | Eli Lilly And Company | Compounds |
| US6720317B1 (en) | 1999-09-17 | 2004-04-13 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
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| AU1770001A (en) * | 1999-11-24 | 2001-06-04 | Cor Therapeutics, Inc. | Beta-amino acid-, aspartic acid- and diaminopropionic-based inhibitors of factorxa |
| DE60115394T2 (de) | 2000-02-29 | 2006-10-19 | Millennium Pharmaceuticals, Inc., Cambridge | Benzamide und ähnliche inhibitoren vom faktor xa |
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| US7160878B2 (en) | 2000-07-27 | 2007-01-09 | Eli Lilly And Company | Substituted heterocyclic amides |
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| US5849759A (en) | 1995-12-08 | 1998-12-15 | Berlex Laboratories, Inc. | Naphthyl-substituted benzimidazole derivatives as anti-coagulants |
| US5994375A (en) * | 1996-02-12 | 1999-11-30 | Berlex Laboratories, Inc. | Benzamidine derivatives substituted by amino acid and hydroxy acid derivatives and their use as anti-coagulants |
| US5693641A (en) | 1996-08-16 | 1997-12-02 | Berlex Laboratories Inc. | Bicyclic pyrimidine derivatives and their use as anti-coagulants |
| US5753635A (en) | 1996-08-16 | 1998-05-19 | Berlex Laboratories, Inc. | Purine derivatives and their use as anti-coagulants |
| ES2188979T3 (es) | 1996-09-12 | 2003-07-01 | Schering Ag | Derivados de benzamidina sustituidos con derivados de aminoacidos ciclicos e hidroxiacidos ciclicos, y su uso como anti-coagulantes. |
| US6004985A (en) | 1996-10-09 | 1999-12-21 | Berlex Laboratories, Inc. | Thio acid derived monocylic N-heterocyclics as anticoagulants |
| ATE297203T1 (de) | 1997-06-26 | 2005-06-15 | Lilly Co Eli | Antithrombotische mitteln |
| IL133625A0 (en) | 1997-06-26 | 2001-04-30 | Lilly Co Eli | Antithrombotic agents |
| JP2002512633A (ja) * | 1997-06-26 | 2002-04-23 | イーライ・リリー・アンド・カンパニー | 抗血栓剤 |
| US6140351A (en) * | 1997-12-19 | 2000-10-31 | Berlex Laboratories, Inc. | Ortho-anthranilamide derivatives as anti-coagulants |
| CA2358095A1 (en) | 1998-12-23 | 2000-07-06 | Eli Lilly And Company | Heteroroaromatic amides as inhibitor of factor xa |
-
1998
- 1998-11-27 RU RU2000119756/04A patent/RU2226529C2/ru not_active IP Right Cessation
- 1998-11-27 CA CA002315070A patent/CA2315070A1/en not_active Abandoned
- 1998-11-27 AT AT98963519T patent/ATE260103T1/de not_active IP Right Cessation
- 1998-11-27 CN CNB988124173A patent/CN1143855C/zh not_active Expired - Fee Related
- 1998-11-27 WO PCT/EP1998/007650 patent/WO1999032477A1/en not_active Application Discontinuation
- 1998-11-27 NZ NZ503809A patent/NZ503809A/en unknown
- 1998-11-27 DK DK98963519T patent/DK1040108T3/da active
- 1998-11-27 EP EP98963519A patent/EP1040108B1/en not_active Expired - Lifetime
- 1998-11-27 DE DE69821985T patent/DE69821985T2/de not_active Expired - Fee Related
- 1998-11-27 AU AU18759/99A patent/AU751856B2/en not_active Ceased
- 1998-11-27 ES ES98963519T patent/ES2215337T3/es not_active Expired - Lifetime
- 1998-11-27 SK SK943-2000A patent/SK9432000A3/sk unknown
- 1998-11-27 JP JP2000525414A patent/JP3811006B2/ja not_active Expired - Fee Related
- 1998-11-27 PL PL98341044A patent/PL341044A1/xx not_active Application Discontinuation
- 1998-11-27 PT PT98963519T patent/PT1040108E/pt unknown
- 1998-11-27 HU HU0101172A patent/HUP0101172A3/hu unknown
- 1998-11-27 IL IL13553698A patent/IL135536A0/xx unknown
-
2000
- 2000-06-16 NO NO20003111A patent/NO20003111L/no not_active Application Discontinuation
- 2000-08-03 US US09/631,452 patent/US6498185B1/en not_active Expired - Fee Related
- 2000-08-03 US US09/631,450 patent/US6380221B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2315070A1 (en) | 1999-07-01 |
| EP1040108B1 (en) | 2004-02-25 |
| PL341044A1 (en) | 2001-03-26 |
| AU1875999A (en) | 1999-07-12 |
| DK1040108T3 (da) | 2004-05-24 |
| AU751856B2 (en) | 2002-08-29 |
| JP2001526283A (ja) | 2001-12-18 |
| WO1999032477B1 (en) | 1999-09-10 |
| ATE260103T1 (de) | 2004-03-15 |
| WO1999032477A1 (en) | 1999-07-01 |
| US6380221B1 (en) | 2002-04-30 |
| RU2226529C2 (ru) | 2004-04-10 |
| JP3811006B2 (ja) | 2006-08-16 |
| NZ503809A (en) | 2002-04-26 |
| HUP0101172A3 (en) | 2002-12-28 |
| IL135536A0 (en) | 2001-05-20 |
| US6498185B1 (en) | 2002-12-24 |
| EP1040108A1 (en) | 2000-10-04 |
| CN1282329A (zh) | 2001-01-31 |
| DE69821985D1 (de) | 2004-04-01 |
| SK9432000A3 (en) | 2001-02-12 |
| CN1143855C (zh) | 2004-03-31 |
| PT1040108E (pt) | 2004-06-30 |
| HUP0101172A1 (hu) | 2002-05-29 |
| ES2215337T3 (es) | 2004-10-01 |
| DE69821985T2 (de) | 2005-05-04 |
| NO20003111D0 (no) | 2000-06-16 |
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