FI955498A - Nipekotiinihappojohdannaisia hyytymistä estävinä aineina - Google Patents

Nipekotiinihappojohdannaisia hyytymistä estävinä aineina Download PDF

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Publication number
FI955498A
FI955498A FI955498A FI955498A FI955498A FI 955498 A FI955498 A FI 955498A FI 955498 A FI955498 A FI 955498A FI 955498 A FI955498 A FI 955498A FI 955498 A FI955498 A FI 955498A
Authority
FI
Finland
Prior art keywords
anticoagulants
acid derivatives
nipecotinic acid
nipecotinic
telet
Prior art date
Application number
FI955498A
Other languages
English (en)
Swedish (sv)
Other versions
FI113763B (fi
FI955498A0 (fi
Inventor
Mary Pat Beavers
Patricia Andrade-Gordon
William J Hoekstra
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of FI955498A0 publication Critical patent/FI955498A0/fi
Publication of FI955498A publication Critical patent/FI955498A/fi
Application granted granted Critical
Publication of FI113763B publication Critical patent/FI113763B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
FI955498A 1994-03-16 1995-11-15 Nipekotiinihappojohdannaisia hyytymistä estävinä aineina FI113763B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US21377294A 1994-03-16 1994-03-16
US21377294 1994-03-16
US36489694A 1994-12-27 1994-12-27
US36489694 1994-12-27
US9503145 1995-03-14
PCT/US1995/003145 WO1995025091A2 (en) 1994-03-16 1995-03-14 Nipecotic acid derivatives as antithrombic compounds

Publications (3)

Publication Number Publication Date
FI955498A0 FI955498A0 (fi) 1995-11-15
FI955498A true FI955498A (fi) 1996-01-15
FI113763B FI113763B (fi) 2004-06-15

Family

ID=26908383

Family Applications (1)

Application Number Title Priority Date Filing Date
FI955498A FI113763B (fi) 1994-03-16 1995-11-15 Nipekotiinihappojohdannaisia hyytymistä estävinä aineina

Country Status (20)

Country Link
US (1) US5770575A (fi)
EP (1) EP0746545B1 (fi)
JP (1) JPH09510453A (fi)
KR (1) KR100328287B1 (fi)
CN (1) CN1083834C (fi)
AT (1) ATE180470T1 (fi)
AU (1) AU703397B2 (fi)
CA (1) CA2163027A1 (fi)
DE (1) DE69509875T2 (fi)
DK (1) DK0746545T3 (fi)
ES (1) ES2131313T3 (fi)
FI (1) FI113763B (fi)
GR (1) GR3030566T3 (fi)
HU (1) HUT74871A (fi)
MX (1) MX9504800A (fi)
NO (1) NO304885B1 (fi)
NZ (1) NZ283209A (fi)
RU (1) RU2135470C1 (fi)
TW (1) TW318179B (fi)
WO (1) WO1995025091A2 (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0669912B1 (en) * 1993-09-22 2001-12-05 Fujisawa Pharmaceutical Co., Ltd. N-(3-piperidinylcarbonyl)-beta-alanine derivatives as paf antagonists
KR19980703107A (ko) * 1995-03-17 1998-10-15 후지야마 아키라 N-아실피페리디닐카보닐아미노카복실산 및 당단백질 IIB/IIa 길항제와 피브리노겐-혈소판 결합 억제제로서의 이의 용도
EP0888302A1 (en) * 1996-03-13 1999-01-07 Fujisawa Pharmaceutical Co., Ltd. N- (r)-1- 3-(4-piperidyl)propionyl-3-piperidylcarbonyl]-2(s)-acetylamino-beta-alanine as fibrinogen receptor antagonist
AU726594B2 (en) * 1996-05-01 2000-11-16 Ortho-Mcneil Pharmaceutical, Inc. Carboxamide derivatives of pyrrolidine, piperidine and hexahydroazepine for the treatment of thrombosis disorders
EP1184374B1 (en) * 1996-05-01 2009-01-28 Ortho-McNeil Pharmaceutical, Inc. Carboxamide derivatives of pyrrolidine, piperidine and hexahydroazepine for the treatment of thrombosis disorders
DE19741235A1 (de) * 1997-09-18 1999-03-25 Hoechst Marion Roussel De Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
US6066651A (en) 1997-10-29 2000-05-23 Ortho-Mcneil Pharmaceutical, Inc. Orally-active nipecotamide glycolamide esters for the treatment of thrombosis disorders
US6020347A (en) * 1997-11-18 2000-02-01 Merck & Co., Inc. 4-substituted-4-piperidine carboxamide derivatives
WO1999025685A1 (en) * 1997-11-18 1999-05-27 Merck & Co., Inc. 4-substituted-4-piperidine carboxamide derivatives
BR0010652A (pt) * 1999-03-22 2002-07-16 Ortho Mcneil Pharm Inc Processo de preparação de ácido [s-(r*,s*)]-beta-[[[1-[1-oxo-3-(4-piperidinil)propil]-3-piperi dinil]carbonil]amino]-3-piridinapropanóico e derivados
AUPQ570100A0 (en) * 2000-02-17 2000-03-09 Fujisawa Pharmaceutical Co., Ltd. Beta-alanine derivatives and their use as receptor antagonists
EP1719529A4 (en) 2004-02-25 2008-05-21 Astellas Pharma Inc CONTRASTING FOR THROMBUS EDUCATION
EP3184149A1 (en) * 2015-12-23 2017-06-28 Julius-Maximilians-Universität Würzburg Soluble glycoprotein v for treating thrombotic diseases
CN109734655B (zh) * 2019-03-11 2020-06-02 都创(上海)医药科技有限公司 一种fkbp配体的同型二聚体合成工艺

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857508A (en) * 1987-12-03 1989-08-15 Monsanto Company Novel platelet-aggregation inhibitor peptide derivatives
US5318899A (en) * 1989-06-16 1994-06-07 Cor Therapeutics, Inc. Platelet aggregation inhibitors
TW201303B (fi) * 1990-07-05 1993-03-01 Hoffmann La Roche
IE912760A1 (en) * 1990-08-06 1992-02-12 Smith Kline French Lab Compounds
ATE158589T1 (de) * 1991-11-22 1997-10-15 Yeda Res & Dev Nicht-peptidische surrogate der arg-gly-asp sequenz und entsprechende pharmazeutische zusammensetzungen
US5219867A (en) * 1991-12-16 1993-06-15 Research Corporation Technologies, Inc. Platelet aggregation inhibitory agents
EP0673387B1 (en) * 1992-12-11 1999-09-22 University Of Florida Materials and methods for control of pests
US5559209A (en) * 1993-02-18 1996-09-24 The General Hospital Corporation Regulator regions of G proteins

Also Published As

Publication number Publication date
NO954609L (no) 1996-01-05
FI113763B (fi) 2004-06-15
DE69509875D1 (de) 1999-07-01
AU703397B2 (en) 1999-03-25
HU9503270D0 (en) 1996-05-28
EP0746545B1 (en) 1999-05-26
GR3030566T3 (en) 1999-10-29
EP0746545A1 (en) 1996-12-11
CA2163027A1 (en) 1995-09-21
NO954609D0 (no) 1995-11-15
US5770575A (en) 1998-06-23
NO304885B1 (no) 1999-03-01
TW318179B (en) 1997-10-21
JPH09510453A (ja) 1997-10-21
AU2119195A (en) 1995-10-03
CN1128022A (zh) 1996-07-31
WO1995025091A3 (en) 1995-10-12
RU2135470C1 (ru) 1999-08-27
DE69509875T2 (de) 1999-12-09
WO1995025091A2 (en) 1995-09-21
HUT74871A (en) 1997-02-28
CN1083834C (zh) 2002-05-01
ES2131313T3 (es) 1999-07-16
ATE180470T1 (de) 1999-06-15
MX9504800A (es) 1997-05-31
NZ283209A (en) 1998-04-27
KR100328287B1 (ko) 2002-10-11
FI955498A0 (fi) 1995-11-15
DK0746545T3 (da) 1999-11-08

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