|
US6221352B1
(en)
|
1989-03-21 |
2001-04-24 |
The Immune Response Corporation |
Method of preventing the proliferation of Vβ14 or Vβ17-Expressing T cells
|
|
US6207645B1
(en)
*
|
1989-03-21 |
2001-03-27 |
The Immune Response Corporation |
Vaccination and methods against diseases resulting from pathogenic responses by specific T cell populations
|
|
US5612035A
(en)
*
|
1989-03-21 |
1997-03-18 |
The Immune Response Corporation |
Vaccination against diseases resulting from pathogenic responses by specific T cell populations
|
|
US5776459A
(en)
*
|
1989-07-19 |
1998-07-07 |
Connetics Corporation |
TCR V beta 5 peptides
|
|
US5298396A
(en)
*
|
1989-11-15 |
1994-03-29 |
National Jewish Center For Immunology And Respiratory Medicine |
Method for identifying T cells disease involved in autoimmune disease
|
|
JPH06507384A
(ja)
*
|
1991-01-22 |
1994-08-25 |
ザ イミューン レスポンス コーポレイション |
特定のt細胞群による病理的応答により生じる疾患に対するワクチン投与および方法
|
|
DE69230612T2
(de)
*
|
1991-05-31 |
2000-06-21 |
Connetics Corp., Palo Alto |
T-zell rezeptorpeptide als therapeutika für immun-verwandte krankheiten
|
|
JPH07504399A
(ja)
*
|
1991-08-28 |
1995-05-18 |
ザ・ウィスター・インスティチュート |
T細胞リセプターに基づいた慢性間接リウマチの治療法
|
|
JPH06511241A
(ja)
*
|
1991-09-23 |
1994-12-15 |
ジェネンテク,インコーポレイテッド |
自己免疫疾患の診断および治療
|
|
CA2126686A1
(en)
*
|
1991-12-24 |
1993-07-08 |
Mark D. Howell |
Vaccination and methods against diseases resulting from pathogenic responses by specific t cell populations
|
|
AU4529793A
(en)
*
|
1992-06-08 |
1994-01-04 |
Colorado State University Research Foundation |
Endogenous ligands for cdr4 of t-cell receptor beta -chains and genes encoding the same
|
|
JPH09500261A
(ja)
*
|
1993-05-14 |
1997-01-14 |
ドクトル エル.ウィレムス−インスティテュート |
ヒトt細胞モノクローン、その産生方法及び感染症、自己免疫疾患、t細胞媒介アレルギー及びガンの診断上のその使用
|
|
US5552300A
(en)
*
|
1994-01-13 |
1996-09-03 |
T Cell Sciences, Inc. |
T cell antigen receptor V region proteins and methods of preparation thereof
|
|
US6034064A
(en)
*
|
1995-04-07 |
2000-03-07 |
Hoechst Pharmaceuticals & Chemicals K.K. |
Peptides and therapeutic agent for autoimmune diseases containing the same
|
|
RU2209633C2
(ru)
*
|
1997-09-19 |
2003-08-10 |
Юниверсити Оф Саузерн Калифорниа |
Т-клеточная вакцина для лечения рассеянного склероза
|
|
WO2001097858A2
(en)
|
2000-06-20 |
2001-12-27 |
Idec Pharmaceuticals Corporation |
Cold anti-cd20 antibody/radiolabeled anti-cd22 antibody combination
|
|
US20020159996A1
(en)
|
2001-01-31 |
2002-10-31 |
Kandasamy Hariharan |
Use of CD23 antagonists for the treatment of neoplastic disorders
|
|
PL373835A1
(en)
|
2001-01-31 |
2005-09-19 |
Biogen Idec Inc. |
Use of cd23 antagonists for the treatment of neoplastic disorders
|
|
WO2004056312A2
(en)
|
2002-12-16 |
2004-07-08 |
Genentech, Inc. |
Immunoglobulin variants and uses thereof
|
|
BRPI0409534A
(pt)
|
2003-04-09 |
2006-04-18 |
Genentech Inc |
métodos para o tratamento de doença autoimune e de artrite reumatóide, método de redução do risco de efeito colateral negativo, usos de um antagonista que se liga a um marcador de superfìcie de células b e uso de um anticorpo que se liga a cd20
|
|
CN102512675A
(zh)
|
2004-06-04 |
2012-06-27 |
健泰科生物技术公司 |
用于治疗多发性硬化的方法
|
|
EP2548575A1
(en)
|
2005-02-15 |
2013-01-23 |
Duke University |
Anti-CD19 antibodies that mediate ADCC for use in treating autoimmune diseases
|
|
WO2006098998A2
(en)
|
2005-03-10 |
2006-09-21 |
Genentech, Inc. |
Methods and compositions for modulating vascular integrity
|
|
JP5047947B2
(ja)
|
2005-05-05 |
2012-10-10 |
デューク ユニバーシティ |
自己免疫疾患のための抗cd19抗体治療
|
|
US8389688B2
(en)
|
2006-03-06 |
2013-03-05 |
Aeres Biomedical, Ltd. |
Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
MX2009011996A
(es)
|
2007-05-07 |
2010-04-21 |
Medimmune Llc |
Anticuerpos anti-coestimulador inducible y su uso en el tratamiento de oncologia, transplante y enfermedad autoinmunologica.
|
|
EP3025714B9
(en)
|
2007-09-14 |
2020-11-18 |
Biogen MA Inc. |
Compositions and methods for the treatment of progressive multifocal leukoencephalopathy (pml)
|
|
JP5490714B2
(ja)
|
2007-11-28 |
2014-05-14 |
メディミューン,エルエルシー |
タンパク質製剤
|
|
EP2113560A1
(en)
*
|
2008-04-28 |
2009-11-04 |
TXCell |
Compositions for treating an arthritic condition
|
|
KR101361905B1
(ko)
|
2008-05-16 |
2014-02-21 |
제넨테크, 인크. |
베타7 인테그린 길항제를 이용한 위장관 염증 장애의 치료를 평가하기 위한 바이오마커의 용도
|
|
TW201014605A
(en)
|
2008-09-16 |
2010-04-16 |
Genentech Inc |
Methods for treating progressive multiple sclerosis
|
|
CA2739663A1
(en)
|
2008-10-10 |
2010-05-15 |
Anaphore, Inc. |
Polypeptides that bind trail-r1 and trail-r2
|
|
WO2010056804A1
(en)
|
2008-11-12 |
2010-05-20 |
Medimmune, Llc |
Antibody formulation
|
|
RU2371201C1
(ru)
*
|
2008-12-15 |
2009-10-27 |
Гурий Петрович Ступаков |
Способ лечения хронических заболеваний
|
|
WO2010075249A2
(en)
|
2008-12-22 |
2010-07-01 |
Genentech, Inc. |
A method for treating rheumatoid arthritis with b-cell antagonists
|
|
EP2414391B1
(en)
|
2009-04-02 |
2018-11-28 |
Roche Glycart AG |
Multispecific antibodies comprising full length antibodies and single chain fab fragments
|
|
MX2012001306A
(es)
|
2009-07-31 |
2012-02-28 |
Genentech Inc |
Inhibicion de matastasis de tumor.
|
|
EP2478013B1
(en)
|
2009-09-16 |
2018-10-24 |
F.Hoffmann-La Roche Ag |
Coiled coil and/or tether containing protein complexes and uses thereof
|
|
WO2011033006A1
(en)
|
2009-09-17 |
2011-03-24 |
F. Hoffmann-La Roche Ag |
Methods and compositions for diagnostics use in cancer patients
|
|
WO2011060015A1
(en)
|
2009-11-11 |
2011-05-19 |
Genentech, Inc. |
Methods and compositions for detecting target proteins
|
|
EP3778917A3
(en)
|
2009-12-04 |
2021-06-09 |
F. Hoffmann-La Roche AG |
Multispecific antibodies, antibody analogs, compositions, and methods
|
|
AR080793A1
(es)
|
2010-03-26 |
2012-05-09 |
Roche Glycart Ag |
Anticuerpos biespecificos
|
|
WO2011133886A2
(en)
|
2010-04-23 |
2011-10-27 |
Genentech, Inc. |
Production of heteromultimeric proteins
|
|
BR112013001847A2
(pt)
|
2010-08-24 |
2016-05-31 |
Hoffmann La Roche |
anticorpo biespecífico, método de preparação do anticorpo biespecífico, do anticorpo biespecífico trivalente, métodos e composição farmacêutica
|
|
KR20130086628A
(ko)
|
2010-11-08 |
2013-08-02 |
제넨테크, 인크. |
피하 투여용 항―il―6 수용체 항체
|
|
EP2655413B1
(en)
|
2010-12-23 |
2019-01-16 |
F.Hoffmann-La Roche Ag |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
|
US10689447B2
(en)
|
2011-02-04 |
2020-06-23 |
Genentech, Inc. |
Fc variants and methods for their production
|
|
JP6161540B2
(ja)
|
2011-02-04 |
2017-07-12 |
ジェネンテック, インコーポレイテッド |
Fc変異体及びそれらの生産方法
|
|
MY189494A
(en)
|
2011-03-31 |
2022-02-16 |
Genentech Inc |
Methods of administering beta7 integrin antagonists
|
|
WO2013013708A1
(en)
|
2011-07-26 |
2013-01-31 |
Fundació Institut D'investigació Biomèdica De Bellvitge |
Treatment of acute rejection in renal transplant
|
|
CA2842481A1
(en)
|
2011-08-17 |
2013-02-21 |
Genentech, Inc. |
Inhibition of angiogenesis in refractory tumors
|
|
WO2013082511A1
(en)
|
2011-12-02 |
2013-06-06 |
Genentech, Inc. |
Methods for overcoming tumor resistance to vegf antagonists
|
|
WO2013101771A2
(en)
|
2011-12-30 |
2013-07-04 |
Genentech, Inc. |
Compositions and method for treating autoimmune diseases
|
|
CA2863066A1
(en)
|
2012-01-31 |
2013-08-08 |
Genentech, Inc. |
Anti-ig-e m1' antibodies and methods using same
|
|
MX2014009565A
(es)
|
2012-02-10 |
2014-11-10 |
Genentech Inc |
Anticuerpos monocatenarios y otros heteromultimeros.
|
|
US8835387B2
(en)
|
2012-02-16 |
2014-09-16 |
Atyr Pharma, Inc. |
Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
|
|
RU2015100656A
(ru)
|
2012-06-27 |
2016-08-20 |
Ф. Хоффманн-Ля Рош Аг |
Способ получения конъюгатов fc-фрагмента антитела, включающих по меньшей мере одну связывающую группировку, которая специфически связывается с мишенью, и их применения
|
|
ES2597228T3
(es)
|
2012-06-27 |
2017-01-17 |
F. Hoffmann-La Roche Ag |
Procedimiento para la selección y la producción de entidades de objetivación, como dianas, altamente selectivas y multiespecíficas, personalizadas, las cuales contienen por lo menos dos entidades de unión diferentes, y utilización de éstas
|
|
CN104870056A
(zh)
|
2012-10-05 |
2015-08-26 |
弗·哈夫曼-拉罗切有限公司 |
用于诊断和治疗炎性肠病的方法
|
|
KR102182488B1
(ko)
|
2013-02-25 |
2020-11-24 |
제넨테크, 인크. |
약물 내성 akt 돌연변이체의 검출 및 치료를 위한 방법 및 조성물
|
|
US9682071B2
(en)
|
2013-03-15 |
2017-06-20 |
Intermune, Inc. |
Methods of improving microvascular integrity
|
|
JP6615745B2
(ja)
|
2013-03-27 |
2019-12-04 |
ジェネンテック, インコーポレイテッド |
ベータ7インテグリンアンタゴニストによる胃腸炎症障害の治療を評価するためのバイオマーカーの使用
|
|
JP7054990B2
(ja)
|
2014-03-27 |
2022-04-15 |
ジェネンテック, インコーポレイテッド |
炎症性腸疾患の診断及び治療のための方法
|
|
WO2015171822A1
(en)
|
2014-05-06 |
2015-11-12 |
Genentech, Inc. |
Production of heteromultimeric proteins using mammalian cells
|
|
WO2016040868A1
(en)
|
2014-09-12 |
2016-03-17 |
Genentech, Inc. |
Anti-cll-1 antibodies and immunoconjugates
|
|
WO2016087416A1
(en)
|
2014-12-03 |
2016-06-09 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies
|
|
MY188799A
(en)
|
2014-12-05 |
2022-01-04 |
Genentech Inc |
Anti-cd79b antibodies and methods of use
|
|
HK1244229A1
(zh)
|
2015-02-26 |
2018-08-03 |
F. Hoffmann-La Roche Ag |
治疗CROHN病的整联蛋白β7拮抗剂和方法
|
|
EP3310378B1
(en)
|
2015-06-16 |
2024-01-24 |
F. Hoffmann-La Roche AG |
Anti-cll-1 antibodies and methods of use
|
|
MY193078A
(en)
|
2015-06-24 |
2022-09-26 |
Hoffmann La Roche |
Anti-transferrin receptor antibodies with tailored affinity
|
|
JP2018520153A
(ja)
|
2015-06-29 |
2018-07-26 |
ジェネンテック, インコーポレイテッド |
臓器移植における使用のためのii型抗cd20抗体
|
|
RU2753390C1
(ru)
|
2015-10-02 |
2021-08-13 |
Ф. Хоффманн-Ля Рош Аг |
Биспецифические антитела к человеческому cd20/человеческому рецептору трансферрина и способы их применения
|
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
|
AR106189A1
(es)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
|
|
CN108431038A
(zh)
|
2015-10-06 |
2018-08-21 |
豪夫迈·罗氏有限公司 |
治疗多发性硬化的方法
|
|
SG11201804961UA
(en)
|
2015-12-30 |
2018-07-30 |
Genentech Inc |
Formulations with reduced degradation of polysorbate
|
|
CN109152843A
(zh)
|
2016-05-20 |
2019-01-04 |
豪夫迈·罗氏有限公司 |
Protac抗体缀合物及其使用方法
|
|
EP3551034A1
(en)
|
2016-12-07 |
2019-10-16 |
Progenity, Inc. |
Gastrointestinal tract detection methods, devices and systems
|
|
MX2019006823A
(es)
|
2016-12-14 |
2019-10-21 |
Progenity Inc |
Tratamiento de una enfermedad del tracto gastrointestinal con inhibidor de interleucina-12/interleucina-23 (il-12/il-23) liberado usando un dispositivo ingerible.
|
|
WO2018112237A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor
|
|
JP2020513280A
(ja)
|
2016-12-14 |
2020-05-14 |
プロジェニティ, インコーポレイテッド |
消化管疾病の免疫抑制剤による治療
|
|
JP7150724B2
(ja)
|
2016-12-14 |
2022-10-11 |
ビオラ・セラピューティクス・インコーポレイテッド |
消化管疾病のtnf阻害薬による治療
|
|
WO2018112235A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with a smad7 inhibitor
|
|
US11426566B2
(en)
|
2016-12-14 |
2022-08-30 |
Biora Therapeutics, Inc. |
Treatment of a disease of the gastrointestinal tract with a TLR modulator
|
|
WO2018112264A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor
|
|
WO2018112245A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with a jak inhibitor and devices
|
|
WO2018183932A1
(en)
|
2017-03-30 |
2018-10-04 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor
|
|
EP3600414A1
(en)
|
2017-03-30 |
2020-02-05 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with il-10 or an il-10 agonist
|
|
WO2018183934A1
(en)
|
2017-03-30 |
2018-10-04 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with a chst15 inhibitor
|
|
CA3054947A1
(en)
|
2017-03-30 |
2018-10-04 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with live biotherapeutics
|
|
CN111601597B
(zh)
|
2017-08-23 |
2023-10-13 |
科智生命科学公司 |
自身免疫性病症的治疗中的免疫蛋白酶体抑制剂和免疫抑制剂
|
|
RU2698048C2
(ru)
|
2017-10-03 |
2019-08-21 |
Закрытое Акционерное Общество "Биокад" |
МОНОКЛОНАЛЬНОЕ АНТИТЕЛО К IL-5Rα
|
|
US20210031012A1
(en)
|
2018-01-26 |
2021-02-04 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with a pde4 inhibitor
|
|
EP3802850B1
(en)
|
2018-06-01 |
2025-11-19 |
BT Bidco, Inc. |
Devices and systems for gastrointestinal microbiome detection and manipulation
|
|
WO2019246317A1
(en)
|
2018-06-20 |
2019-12-26 |
Progenity, Inc. |
Treatment of a disease or condition in a tissue originating from the endoderm
|
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
|
WO2020086858A1
(en)
|
2018-10-24 |
2020-04-30 |
Genentech, Inc. |
Conjugated chemical inducers of degradation and methods of use
|
|
RU2724469C2
(ru)
|
2018-10-31 |
2020-06-23 |
Закрытое Акционерное Общество "Биокад" |
Моноклональное антитело, которое специфически связывается с cd20
|
|
US20240252795A1
(en)
|
2018-11-19 |
2024-08-01 |
Biora Therapeutics, Inc. |
Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
|
|
US20220364171A1
(en)
|
2018-11-23 |
2022-11-17 |
Katholieke Universiteit Leuven |
Predicting a treatment response in inflammatory bowel disease
|
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
|
CA3106693A1
(en)
|
2019-02-06 |
2020-08-13 |
Sangamo Therapeutics, Inc. |
Method for the treatment of mucopolysaccharidosis type i
|
|
KR20210146986A
(ko)
|
2019-04-02 |
2021-12-06 |
상가모 테라퓨틱스, 인코포레이티드 |
베타-지중해빈혈의 치료 방법
|
|
EP3870261B1
(en)
|
2019-12-13 |
2024-01-31 |
Biora Therapeutics, Inc. |
Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
|
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
|
WO2023086910A1
(en)
|
2021-11-12 |
2023-05-19 |
Genentech, Inc. |
Methods of treating crohn's disease using integrin beta7 antagonists
|
|
EP4433506A1
(en)
|
2021-11-16 |
2024-09-25 |
Genentech, Inc. |
Methods and compositions for treating systemic lupus erythematosus (sle) with mosunetuzumab
|
|
EP4633738A1
(en)
|
2022-12-14 |
2025-10-22 |
Pheon Therapeutics Ltd |
Cytotoxic compounds
|