NO20002359L - Adenosinderivater og farmasoytisk sammensetning inneholdende derivatene - Google Patents

Adenosinderivater og farmasoytisk sammensetning inneholdende derivatene

Info

Publication number
NO20002359L
NO20002359L NO20002359A NO20002359A NO20002359L NO 20002359 L NO20002359 L NO 20002359L NO 20002359 A NO20002359 A NO 20002359A NO 20002359 A NO20002359 A NO 20002359A NO 20002359 L NO20002359 L NO 20002359L
Authority
NO
Norway
Prior art keywords
derivatives
pharmaceutical composition
composition containing
adenosine
adenosine derivatives
Prior art date
Application number
NO20002359A
Other languages
English (en)
Norwegian (no)
Other versions
NO20002359D0 (no
Inventor
Andrew Michael Kenneth Pennell
Colin David Eldred
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO20002359D0 publication Critical patent/NO20002359D0/no
Publication of NO20002359L publication Critical patent/NO20002359L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NO20002359A 1997-11-08 2000-05-05 Adenosinderivater og farmasoytisk sammensetning inneholdende derivatene NO20002359L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9723590.7A GB9723590D0 (en) 1997-11-08 1997-11-08 Chemical compounds
PCT/EP1998/007023 WO1999024451A2 (fr) 1997-11-08 1998-11-06 Composes chimiques

Publications (2)

Publication Number Publication Date
NO20002359D0 NO20002359D0 (no) 2000-05-05
NO20002359L true NO20002359L (no) 2000-07-05

Family

ID=10821761

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002359A NO20002359L (no) 1997-11-08 2000-05-05 Adenosinderivater og farmasoytisk sammensetning inneholdende derivatene

Country Status (27)

Country Link
US (2) US6544960B1 (fr)
EP (1) EP1030856B1 (fr)
JP (1) JP2001522859A (fr)
KR (1) KR20010031878A (fr)
CN (1) CN1217952C (fr)
AP (1) AP2000001804A0 (fr)
AT (1) ATE273989T1 (fr)
AU (1) AU763414B2 (fr)
BR (1) BR9813989A (fr)
CA (1) CA2309202C (fr)
DE (1) DE69825779T2 (fr)
EA (1) EA003087B1 (fr)
EE (1) EE04499B1 (fr)
ES (1) ES2222619T3 (fr)
GB (1) GB9723590D0 (fr)
HR (1) HRP20000277A2 (fr)
HU (1) HUP0004102A3 (fr)
ID (1) ID24758A (fr)
IL (2) IL135966A0 (fr)
IS (1) IS5479A (fr)
NO (1) NO20002359L (fr)
NZ (1) NZ504336A (fr)
PL (1) PL340873A1 (fr)
SK (1) SK6702000A3 (fr)
TR (1) TR200001937T2 (fr)
WO (1) WO1999024451A2 (fr)
YU (1) YU26800A (fr)

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US7713946B2 (en) 2002-07-11 2010-05-11 Cv Therapeutics, Inc. Partial and full agonists A1 adenosine receptors
US6946449B2 (en) 2001-07-13 2005-09-20 Cv Therapeutics, Inc. Partial and full agonists of A1 adenosine receptors
US7157440B2 (en) 2001-07-13 2007-01-02 Cv Therapeutics, Inc. Partial and full agonists of A1 adenosine receptors
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US7163928B2 (en) 2003-02-03 2007-01-16 Cv Therapeutics, Inc. Partial and full agonists of A1 adenosine receptors
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GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
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WO2008052734A1 (fr) 2006-10-30 2008-05-08 Novartis Ag Composés hétérocycliques en tant qu'agents anti-inflammatoires
EP2240017B1 (fr) 2008-01-04 2019-03-13 Oxford University Innovation Limited Corps cétoniques et esters de corps cétoniques convenant comme hypolipémiants sanguins
JP5584138B2 (ja) 2008-01-11 2014-09-03 ノバルティス アーゲー キナーゼ阻害剤としてのピリミジン類
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CN101857622B (zh) * 2009-04-07 2014-12-03 中国医学科学院药物研究所 一种腺苷衍生物及其制备方法和应用
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
AU2010283806A1 (en) 2009-08-12 2012-03-01 Novartis Ag Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation
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CN104382924B (zh) * 2009-12-10 2017-12-22 中国医学科学院药物研究所 N6‑取代腺苷衍生物和n6‑取代腺嘌呤衍生物及其用途
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WO2012034095A1 (fr) 2010-09-09 2012-03-15 Irm Llc Composés et compositions comme inhibiteurs de trk
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
US20130324526A1 (en) 2011-02-10 2013-12-05 Novartis Ag [1,2,4] triazolo [4,3-b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
JP5808826B2 (ja) 2011-02-23 2015-11-10 インテリカイン， エルエルシー 複素環化合物およびその使用
AU2012220572A1 (en) 2011-02-25 2013-08-29 Irm Llc Compounds and compositions as trk inhibitors
US9062045B2 (en) 2011-09-15 2015-06-23 Novartis Ag Triazolopyridine compounds
JP6130391B2 (ja) 2011-11-23 2017-05-17 インテリカイン， エルエルシー Ｍｔｏｒ阻害剤を使用する強化された治療レジメン
RS56150B1 (sr) 2012-01-26 2017-11-30 Inotek Pharmaceuticals Corp Anhidrovani polimorfi (2r,3s,4r,5r)-5-(6-(ciklopentilamino)-9h-purin-9-yl)-3,4-dihidroksitetrahidrofuran-2-yl)} metil-nitrata i postupak njegove pripreme
CN110507654A (zh) 2012-04-03 2019-11-29 诺华有限公司 有酪氨酸激酶抑制剂的组合产品和其应用
ES2752030T3 (es) 2012-11-05 2020-04-02 Us Health Cuerpos cetónicos para proteger los tejidos del daño por radiación ionizante
GB201304467D0 (en) 2013-03-12 2013-04-24 Tdeltas Ltd Compound for use in protecting skin
AU2014230120B2 (en) 2013-03-14 2018-06-21 Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services Process for producing (R)-3hydroxybutyl (R)-3hydroxybutyrate
EP2968340A4 (fr) 2013-03-15 2016-08-10 Intellikine Llc Combinaison d'inhibiteurs de kinase et ses utilisations
JP2016513706A (ja) 2013-03-15 2016-05-16 イノテック ファーマシューティカルズ コーポレイション 点眼用製剤
TW201605450A (zh) 2013-12-03 2016-02-16 諾華公司 Ｍｄｍ２抑制劑與ＢＲＡＦ抑制劑之組合及其用途
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CA2954862A1 (fr) 2014-07-31 2016-02-04 Novartis Ag Polytherapie
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Also Published As

Publication number Publication date
HUP0004102A2 (hu) 2001-04-28
US6544960B1 (en) 2003-04-08
EA003087B1 (ru) 2002-12-26
DE69825779D1 (de) 2004-09-23
ES2222619T3 (es) 2005-02-01
AP2000001804A0 (en) 2000-06-30
JP2001522859A (ja) 2001-11-20
GB9723590D0 (en) 1998-01-07
CA2309202A1 (fr) 1999-05-20
IL135966A (en) 2006-06-11
HUP0004102A3 (en) 2002-09-30
KR20010031878A (ko) 2001-04-16
DE69825779T2 (de) 2005-08-25
CN1217952C (zh) 2005-09-07
NZ504336A (en) 2002-11-26
US20030158146A1 (en) 2003-08-21
US6740644B2 (en) 2004-05-25
EE04499B1 (et) 2005-06-15
AU763414B2 (en) 2003-07-24
NO20002359D0 (no) 2000-05-05
IL135966A0 (en) 2001-05-20
BR9813989A (pt) 2000-09-26
YU26800A (sh) 2002-12-10
IS5479A (is) 2000-05-03
WO1999024451A2 (fr) 1999-05-20
CA2309202C (fr) 2008-06-17
SK6702000A3 (en) 2001-01-18
TR200001937T2 (tr) 2000-11-21
EE200000283A (et) 2001-08-15
EP1030856A2 (fr) 2000-08-30
EA200000398A1 (ru) 2000-12-25
ID24758A (id) 2000-08-03
PL340873A1 (en) 2001-03-12
EP1030856B1 (fr) 2004-08-18
CN1285844A (zh) 2001-02-28
AU1666599A (en) 1999-05-31
WO1999024451A3 (fr) 1999-08-19
HRP20000277A2 (en) 2000-10-31
ATE273989T1 (de) 2004-09-15

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