DE69838172T2
(de)
|
1997-08-22 |
2008-04-10 |
Astrazeneca Ab |
Oxindolylchinazolinderivate als angiogenesehemmer
|
EP1006113A1
(en)
|
1998-12-02 |
2000-06-07 |
Pfizer Products Inc. |
Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and their use to inhibit abnormal cell growth
|
UA71945C2
(en)
*
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
GB9918057D0
(en)
*
|
1999-07-30 |
1999-10-06 |
Univ Bristol |
Therapeutic agents
|
UA74803C2
(uk)
|
1999-11-11 |
2006-02-15 |
Осі Фармасьютікалз, Інк. |
Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
|
GB0010757D0
(en)
*
|
2000-05-05 |
2000-06-28 |
Astrazeneca Ab |
Chemical compounds
|
AU2001252463A1
(en)
|
2000-06-06 |
2001-12-17 |
Pfizer Products Inc. |
Thiophene derivatives useful as anticancer agents
|
MXPA03000874A
(es)
*
|
2000-08-09 |
2003-06-06 |
Astrazeneca Ab |
Compuestos quimicos.
|
EP1318984A1
(en)
|
2000-09-20 |
2003-06-18 |
MERCK PATENT GmbH |
4-amino-quinazolines
|
US6503914B1
(en)
*
|
2000-10-23 |
2003-01-07 |
Board Of Regents, The University Of Texas System |
Thienopyrimidine-based inhibitors of the Src family
|
AUPR213700A0
(en)
*
|
2000-12-18 |
2001-01-25 |
Biota Scientific Management Pty Ltd |
Antiviral agents
|
KR20020051675A
(ko)
*
|
2000-12-23 |
2002-06-29 |
이상남 |
4-페닐아미노티에노 [3,2-디] 피리미딘 유도체 및 이의제조방법
|
MX337162B
(es)
|
2001-01-05 |
2016-02-15 |
Pfizer |
Anticuerpos contra el receptor del factor de crecimiento similar a insulina.
|
DE60212487T2
(de)
*
|
2001-04-13 |
2006-12-21 |
Pfizer Products Inc., Groton |
Bizyklisch substituierte 4-Aminopyridopyrimidinderivate
|
WO2003000194A2
(en)
|
2001-06-21 |
2003-01-03 |
Pfizer Inc. |
Thienopyridine and thienopyrimidine anticancer agents
|
US7829566B2
(en)
|
2001-09-17 |
2010-11-09 |
Werner Mederski |
4-amino-quinazolines
|
AR039067A1
(es)
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
EP1463507A1
(en)
*
|
2001-12-19 |
2004-10-06 |
SmithKline Beecham Corporation |
Thienopyrimidine compounds as protein tyrosine kinase inhibitors
|
AU2002364211A1
(en)
*
|
2001-12-21 |
2003-07-15 |
Bayer Pharmaceuticals Corporation |
Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
|
US20040014755A1
(en)
*
|
2002-01-10 |
2004-01-22 |
Dhanapalan Nagarathnam |
Rho-kinase inhibitors
|
MXPA04007191A
(es)
|
2002-01-23 |
2005-03-31 |
Bayer Pharmaceuticals Corp |
Derivados de pirimidina como inhibidores de rho-quinasa.
|
JP4423043B2
(ja)
|
2002-01-23 |
2010-03-03 |
バイエル ファーマセチカル コーポレーション |
Rho−キナーゼ阻害剤
|
WO2003064428A1
(en)
*
|
2002-01-29 |
2003-08-07 |
H. Lundbeck A/S |
Furano- and thienopyrimidines as neurokinase inhibitors
|
US7071190B2
(en)
|
2002-02-15 |
2006-07-04 |
Rigel Pharmaceuticals, Inc. |
Inhibitors to tubulin polymerization
|
US20030225273A1
(en)
*
|
2002-03-21 |
2003-12-04 |
Michaelides Michael R. |
Thiopyrimidine and isothiazolopyrimidine kinase inhibitors
|
UA77303C2
(en)
|
2002-06-14 |
2006-11-15 |
Pfizer |
Derivatives of thienopyridines substituted by benzocondensed heteroarylamide useful as therapeutic agents, pharmaceutical compositions and methods for their use
|
DE60304718T2
(de)
|
2002-08-06 |
2007-04-26 |
Astrazeneca Ab |
Kondensierte pyridine und pyrimidine mit tie2 (tek) aktivität
|
AR042052A1
(es)
*
|
2002-11-15 |
2005-06-08 |
Vertex Pharma |
Diaminotriazoles utiles como inhibidores de proteinquinasas
|
CL2003002287A1
(es)
*
|
2002-11-25 |
2005-01-14 |
Wyeth Corp |
COMPUESTOS DERIVADOS DE TIENO[3,2-b]-PIRIDINA-6-CARBONITRILOS Y TIENEO[2,3-b]-PIRIDINA-5-CARBONITRILOS, COMPOSICION FARMACEUTICA, PROCEDIMIENTO DE PREPARACION Y COMPUESTOS INTERMEDIARIOS, Y SU USO EN EL TRATAMIENTO DEL CANCER, APOPLEJIA, OSTEOPOROSIS
|
US7276519B2
(en)
*
|
2002-11-25 |
2007-10-02 |
Wyeth |
Thieno[3,2-b]pyridine-6-carbonitriles and thieno[2,3-b]pyridine-5-carbonitriles as protein kinase inhibitors
|
DE60314013T2
(de)
|
2002-12-19 |
2008-01-17 |
Pfizer Inc. |
2-(1h-indazol-6-ylamino)- benzamid-verbindungen als protein kinase inhibitoren und deren verwendung zur behandlung von ophthalmischen krankheiten
|
CA2529611C
(en)
|
2002-12-20 |
2009-12-15 |
Pfizer Products Inc. |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
DK2476667T3
(da)
|
2003-02-26 |
2014-09-15 |
Sugen Inc |
Aminoheteroaryl-forbindelser som proteinkinase-inhibitorer
|
WO2005010008A1
(en)
*
|
2003-07-24 |
2005-02-03 |
Bayer Pharmaceuticals Corporation |
Substituted tetrahydrobenzothienopyrimidinamine compounds useful for treating hyper-proliferative disorders
|
CA2534921C
(en)
*
|
2003-08-06 |
2011-06-14 |
Vertex Pharmaceuticals Incorporated |
Aminotriazole compounds useful as inhibitors of protein kinases
|
US7501427B2
(en)
|
2003-08-14 |
2009-03-10 |
Array Biopharma, Inc. |
Quinazoline analogs as receptor tyrosine kinase inhibitors
|
PL1660090T3
(pl)
|
2003-08-14 |
2013-04-30 |
Array Biopharma Inc |
Analogi chinazoliny jako inhibitory kinaz tyrozynowych receptora
|
WO2005021554A1
(en)
|
2003-08-29 |
2005-03-10 |
Pfizer Inc. |
Thienopyridine-phenylacet amides and their derivatives useful as new anti-angiogenic agents
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
US7332521B2
(en)
*
|
2003-09-25 |
2008-02-19 |
Wyeth |
Substituted indoles
|
US7419978B2
(en)
|
2003-10-22 |
2008-09-02 |
Bristol-Myers Squibb Company |
Phenyl-aniline substituted bicyclic compounds useful as kinase inhibitors
|
EP1699780A1
(en)
|
2003-12-23 |
2006-09-13 |
Pfizer, Inc. |
Novel quinoline derivatives
|
US7470712B2
(en)
*
|
2004-01-21 |
2008-12-30 |
Bristol-Myers Squibb Company |
Amino-benzazoles as P2Y1 receptor inhibitors
|
US20080242681A1
(en)
*
|
2004-01-22 |
2008-10-02 |
Altana Pharma Ag |
N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors
|
CA2566160C
(en)
*
|
2004-05-27 |
2011-01-18 |
Pfizer Products Inc. |
Pyrrolopyrimidine derivatives useful in cancer treatment
|
GB0412467D0
(en)
*
|
2004-06-04 |
2004-07-07 |
Astrazeneca Ab |
Chemical compounds
|
US7173031B2
(en)
*
|
2004-06-28 |
2007-02-06 |
Bristol-Myers Squibb Company |
Pyrrolotriazine kinase inhibitors
|
BRPI0512547A
(pt)
|
2004-06-28 |
2008-03-25 |
Altana Pharma Ag |
pirimidinas
|
ES2438017T3
(es)
*
|
2004-07-30 |
2014-01-15 |
Methylgene Inc. |
Inhibidores de la señalización del receptor del VEGF y del receptor del HGF
|
GEP20104906B
(en)
|
2004-08-26 |
2010-02-25 |
Pfizer |
Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors
|
GB0423653D0
(en)
*
|
2004-10-25 |
2004-11-24 |
Piramed Ltd |
Pharmaceutical compounds
|
AU2005302279A1
(en)
*
|
2004-10-28 |
2006-05-11 |
Irm Llc |
Compounds and compositions as hedgehog pathway modulators
|
US7576080B2
(en)
|
2004-12-23 |
2009-08-18 |
Memory Pharmaceuticals Corporation |
Certain thienopyrimidine derivatives as phosphodiesterase 10 inhibitors
|
EP1841734B1
(en)
*
|
2005-01-19 |
2009-07-29 |
F. Hoffmann-Roche AG |
5-aminoindole derivatives
|
US8093011B2
(en)
|
2005-03-16 |
2012-01-10 |
Haley John D |
Biological markers predictive of anti-cancer response to epidermal growth factor receptor kinase inhibitors
|
WO2006105488A2
(en)
|
2005-03-31 |
2006-10-05 |
Agensys, Inc. |
Antibodies and related molecules that bind to 161p2f10b proteins
|
BRPI0608096A2
(pt)
|
2005-04-26 |
2009-11-10 |
Pfizer |
anticorpos p-caderina
|
NZ564283A
(en)
|
2005-05-20 |
2011-07-29 |
Methylgene Inc |
Inhibitors of VEGF receptor and HGF receptor signaling
|
NZ563774A
(en)
*
|
2005-05-20 |
2010-04-30 |
Methylgene Inc |
Inhibitors of VEGF receptor and HGF receptor signaling
|
US20060281768A1
(en)
*
|
2005-06-10 |
2006-12-14 |
Gaul Michael D |
Thienopyrimidine and thienopyridine kinase modulators
|
WO2006136402A1
(en)
*
|
2005-06-22 |
2006-12-28 |
Develogen Aktiengesellschaft |
Thienopyrimidines for pharmaceutical compositions
|
US7608592B2
(en)
|
2005-06-30 |
2009-10-27 |
Virobay, Inc. |
HCV inhibitors
|
AR055625A1
(es)
*
|
2005-09-02 |
2007-08-29 |
Pfizer |
Procedimientos mejorados para preparar derivados de tienopiridinas heteroaril amida benzocondensados
|
TWI370137B
(en)
|
2005-09-07 |
2012-08-11 |
Amgen Fremont Inc |
Human monoclonal antibodies to activin receptor-like kinase-1
|
ATE533057T1
(de)
|
2005-09-20 |
2011-11-15 |
Osi Pharm Inc |
Biologische marker als prädiktoren der antikrebsreaktion auf insulinähnlichen wachstumsfaktor-1-rezeptor-kinaseinhibitoren
|
PE20070619A1
(es)
*
|
2005-09-27 |
2007-07-02 |
Wyeth Corp |
TIENO(2,3-b)PIRIDIN-5-CARBONITRILOS COMO INHIBIDORES DE PROTEINAS QUINASA
|
WO2007056208A2
(en)
*
|
2005-11-02 |
2007-05-18 |
Cytovia, Inc. |
N-arylalkyl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof
|
US20070099877A1
(en)
*
|
2005-11-02 |
2007-05-03 |
Cytovia, Inc. |
N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof
|
US20070213305A1
(en)
*
|
2005-11-02 |
2007-09-13 |
Cytovia, Inc. |
N-alkyl-N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof
|
JP5134548B2
(ja)
|
2005-11-15 |
2013-01-30 |
アレイ バイオファーマ、インコーポレイテッド |
過剰増殖性疾患の処置のためのErbBI型受容体チロシンキナーゼ阻害剤としてのN4−フェニルキナゾリン−4−アミン誘導体および関連化合物
|
US8003662B2
(en)
*
|
2006-01-30 |
2011-08-23 |
Array Biopharma, Inc. |
Heterobicyclic thiophene compounds and methods of use
|
AR060061A1
(es)
*
|
2006-03-22 |
2008-05-21 |
Methylgene Inc |
Inhibidores de la actividad de la proteina tirosina quinasa
|
MX2008012482A
(es)
*
|
2006-03-31 |
2008-10-10 |
Abbott Lab |
Compuestos de indazol.
|
CA2651898A1
(en)
|
2006-04-07 |
2007-10-18 |
Develogen Aktiengesellschaft |
Thienopyrimidines having mnk1/mnk2 inhibiting activity for pharmaceutical compositions
|
CN101490046A
(zh)
|
2006-05-09 |
2009-07-22 |
辉瑞产品公司 |
环烷基氨基酸衍生物及其药物组合物
|
EP1889847A1
(en)
|
2006-07-10 |
2008-02-20 |
DeveloGen Aktiengesellschaft |
Pyrrolopyrimidines for pharmaceutical compositions
|
WO2008058126A2
(en)
|
2006-11-06 |
2008-05-15 |
Supergen, Inc. |
Imidazo[1,2-b]pyridazine and pyrazolo[1,5-a]pyrimidine derivatives and their use as protein kinase inhibitors
|
AU2007329352B2
(en)
|
2006-12-07 |
2013-01-17 |
F. Hoffmann-La Roche Ag |
Phosphoinositide 3-kinase inhibitor compounds and methods of use
|
CA2946305C
(en)
*
|
2006-12-29 |
2019-09-17 |
Rigel Pharmaceuticals, Inc. |
Substituted triazoles useful as axl inhibitors
|
WO2008082839A2
(en)
*
|
2006-12-29 |
2008-07-10 |
Abbott Laboratories |
Pim kinase inhibitors as cancer chemotherapeutics
|
WO2008086053A1
(en)
*
|
2007-01-03 |
2008-07-17 |
Virobay, Inc. |
Hcv inhibitors
|
US7893060B2
(en)
*
|
2007-06-12 |
2011-02-22 |
F. Hoffmann-La Roche Ag |
Thiazolopyrimidines and their use as inhibitors of phosphatidylinositol-3 kinase
|
EP2014663A1
(de)
*
|
2007-07-12 |
2009-01-14 |
Bayer Schering Pharma AG |
Thienopyrimidylamine als Modulatoren des EP2-Rezeptors
|
EP2014662A1
(de)
*
|
2007-07-12 |
2009-01-14 |
Bayer Schering Pharma Aktiengesellschaft |
Indolylalkylthienopyrimidylamine als Modulatoren des EP2-Rezeptors
|
CA2704711C
(en)
|
2007-09-24 |
2016-07-05 |
Genentech, Inc. |
Thiazolopyrimidine p13k inhibitor compounds and methods of use
|
NZ592534A
(en)
*
|
2007-10-18 |
2013-03-28 |
Boehringer Ingelheim Int |
Preparation of dihydrothieno [3,2-D] pyrimidines and intermediates used therein
|
WO2009055730A1
(en)
*
|
2007-10-25 |
2009-04-30 |
Genentech, Inc. |
Process for making thienopyrimidine compounds
|
RU2503679C2
(ru)
*
|
2007-11-15 |
2014-01-10 |
Джилид Сайенсиз, Инк. |
Ингибиторы репликации вируса иммунодефицита человека
|
AU2008331867B2
(en)
|
2007-11-28 |
2014-05-22 |
Dana-Farber Cancer Institute, Inc. |
Small molecule myristate inhibitors of Bcr-abl and methods of use
|
NZ595781A
(en)
*
|
2008-01-11 |
2013-07-26 |
Glenmark Pharmaceuticals Sa |
Fused pyrimidine derivatives as trpv3 modulators
|
EA201001262A1
(ru)
|
2008-02-07 |
2011-04-29 |
Вайробей, Инк. |
Ингибиторы катепсина в
|
EP2262815A4
(en)
|
2008-03-05 |
2012-04-11 |
Methylgene Inc |
Inhibitors of protein intolerance activity
|
US8119647B2
(en)
|
2008-04-23 |
2012-02-21 |
Glenmark Pharmaceuticals S.A. |
Fused pyrimidineone compounds as TRPV3 modulators
|
WO2010023181A1
(en)
|
2008-08-26 |
2010-03-04 |
Boehringer Ingelheim International Gmbh |
Thienopyrimidines for pharmaceutical compositions
|
US8476410B2
(en)
|
2008-10-16 |
2013-07-02 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Fully human antibodies to high molecular weight-melanoma associated antigen and uses thereof
|
KR101126736B1
(ko)
*
|
2008-11-27 |
2012-04-12 |
주식회사 레고켐 바이오사이언스 |
티로신 키나아제 저해 화합물, 이의 이성질체 또는 이의 약학적으로 허용가능한 염 및 이를 포함하는 약학적 조성물
|
US20100204221A1
(en)
|
2009-02-09 |
2010-08-12 |
Hariprasad Vankayalapati |
Pyrrolopyrimidinyl axl kinase inhibitors
|
JP2012518657A
(ja)
|
2009-02-25 |
2012-08-16 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
併用抗癌治療
|
EP2400990A2
(en)
|
2009-02-26 |
2012-01-04 |
OSI Pharmaceuticals, LLC |
In situ methods for monitoring the emt status of tumor cells in vivo
|
WO2010099138A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
TW201035088A
(en)
|
2009-02-27 |
2010-10-01 |
Supergen Inc |
Cyclopentathiophene/cyclohexathiophene DNA methyltransferase inhibitors
|
JP2012519281A
(ja)
|
2009-02-27 |
2012-08-23 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
間葉様腫瘍細胞またはその生成を阻害する薬剤を同定するための方法
|
JP2012519282A
(ja)
|
2009-02-27 |
2012-08-23 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
間葉様腫瘍細胞またはその生成を阻害する薬剤を同定するための方法
|
US8536161B2
(en)
|
2009-03-12 |
2013-09-17 |
Genentech, Inc. |
Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies
|
CA2761445A1
(en)
*
|
2009-05-27 |
2010-12-02 |
Genentech, Inc. |
Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
CA2772371A1
(en)
*
|
2009-05-27 |
2010-12-02 |
F. Hoffmann-La Roche Ag |
Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
KR20120106935A
(ko)
|
2009-07-13 |
2012-09-27 |
제넨테크, 인크. |
암의 치료를 위한 진단 방법 및 조성물
|
WO2011014726A1
(en)
|
2009-07-31 |
2011-02-03 |
Osi Pharmaceuticals, Inc. |
Mtor inhibitor and angiogenesis inhibitor combination therapy
|
EP2473500A2
(en)
|
2009-09-01 |
2012-07-11 |
Pfizer Inc. |
Benzimidazole derivatives
|
RU2012114094A
(ru)
|
2009-09-11 |
2013-10-20 |
Дженентек, Инк. |
Способ идентификации пациента с увеличенной вероятностью ответа на противораковый агент
|
JP5606537B2
(ja)
|
2009-09-17 |
2014-10-15 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
癌患者における診断使用のための方法及び組成物
|
WO2011073521A1
(en)
|
2009-12-15 |
2011-06-23 |
Petri Salven |
Methods for enriching adult-derived endothelial progenitor cells and uses thereof
|
EP4166558A1
(en)
|
2010-02-12 |
2023-04-19 |
Pfizer Inc. |
Salts and polymorphs of 8-fluoro-2-{4- [(methylamino)methyl]phenyl}-1 ,3,4,5-tetrahydro-6h-azepino[5,4,3- cd]indol-6-one
|
US8754079B2
(en)
|
2010-02-26 |
2014-06-17 |
Boehringer Ingelheim International Gmbh |
Cycloalkyl containing thienopyrimidines for pharmaceutical compositions
|
EA201201192A1
(ru)
|
2010-02-26 |
2013-04-30 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Тиенопиримидины, содержащие замещенную алкильную группу, предназначенные для фармацевтических композиций
|
UY33241A
(es)
|
2010-02-26 |
2011-09-30 |
Boehringer Ingelheim Int |
?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?.
|
WO2011109572A2
(en)
|
2010-03-03 |
2011-09-09 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
AU2011223655A1
(en)
|
2010-03-03 |
2012-06-28 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
EP2558864A1
(en)
|
2010-04-16 |
2013-02-20 |
Genentech, Inc. |
Fox03a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy
|
CN102250112A
(zh)
*
|
2010-05-18 |
2011-11-23 |
上海再启生物技术有限公司 |
7-溴-4-氨基噻吩并嘧啶的制备方法
|
WO2011149126A1
(ko)
*
|
2010-05-26 |
2011-12-01 |
한국과학기술연구원 |
타이로신 카이네이즈 저해능을 가지는 항염증 화합물을 포함하는 약학적 조성물
|
ES2647586T3
(es)
*
|
2010-05-26 |
2017-12-22 |
Korea Institute Of Science And Technology |
Compuesto antiinflamatorio que tiene actividad inhibidora contra múltiples tirosina cinasas, y composición farmacéutica que contiene el mismo
|
WO2011153224A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of cancer
|
ES2695899T3
(es)
|
2010-06-16 |
2019-01-11 |
Univ Pittsburgh Commonwealth Sys Higher Education |
Anticuerpos contra endoplasmina y su uso
|
CN103003262A
(zh)
|
2010-07-16 |
2013-03-27 |
协和发酵麒麟株式会社 |
含氮芳香族杂环衍生物
|
KR20130055647A
(ko)
|
2010-07-19 |
2013-05-28 |
에프. 호프만-라 로슈 아게 |
항암요법에 반응할 가능성이 증가된 환자를 확인하는 방법
|
CA2804246A1
(en)
|
2010-07-19 |
2012-01-26 |
F. Hoffmann-La Roche Ag |
Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy
|
EP3696195B1
(en)
|
2010-07-23 |
2024-02-14 |
Trustees of Boston University |
Anti-despr inhibitors as therapeutics for inhibition of pathological angiogenesis and tumor cell invasiveness and for molecular imaging and targeted delivery
|
MX2013003101A
(es)
|
2010-09-17 |
2013-09-26 |
Purdue Pharma Lp |
Compuestos de piridina y sus usos.
|
WO2012042421A1
(en)
|
2010-09-29 |
2012-04-05 |
Pfizer Inc. |
Method of treating abnormal cell growth
|
JP5802756B2
(ja)
|
2010-10-20 |
2015-11-04 |
ファイザー・インク |
スムーズンド受容体モジュレーターとしてのピリジン−2−誘導体
|
WO2012088254A1
(en)
|
2010-12-22 |
2012-06-28 |
Genentech, Inc. |
Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
|
WO2012106522A2
(en)
|
2011-02-04 |
2012-08-09 |
Duquesne University Of The Holy Spirit |
Bicyclic and tricyclic pyrimidine tyrosine kinase inhibitors with antitubulin activity and methods of treating a patient
|
US20120214830A1
(en)
|
2011-02-22 |
2012-08-23 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors in hepatocellular carcinoma
|
WO2012142164A1
(en)
|
2011-04-12 |
2012-10-18 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
|
TR201905909T4
(tr)
|
2011-04-19 |
2019-05-21 |
Pfizer |
Kanser tedavisi için anti-4-1bb antikorlarının ve adcc indükleyici antikorların kombinasyonları.
|
WO2012149014A1
(en)
|
2011-04-25 |
2012-11-01 |
OSI Pharmaceuticals, LLC |
Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment
|
EP2734530A1
(en)
|
2011-07-19 |
2014-05-28 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
WO2013013188A1
(en)
|
2011-07-21 |
2013-01-24 |
Tolero Pharmaceuticals, Inc. |
Heterocyclic protein kinase inhibitors
|
ES2575710T3
(es)
|
2011-09-22 |
2016-06-30 |
Pfizer Inc |
Derivados de pirrolopirimidina y purina
|
WO2013050725A1
(en)
|
2011-10-04 |
2013-04-11 |
King's College London |
Ige anti -hmw-maa antibody
|
CN103087077B
(zh)
*
|
2011-11-03 |
2016-05-18 |
上海希迈医药科技有限公司 |
噻吩并嘧啶和呋喃并嘧啶类衍生物、其制备方法及其在医药上的应用
|
AU2012335247A1
(en)
|
2011-11-08 |
2014-05-29 |
Pfizer Inc. |
Methods of treating inflammatory disorders using anti-M-CSF antibodies
|
WO2013104575A1
(en)
|
2012-01-10 |
2013-07-18 |
F. Hoffmann-La Roche Ag |
Thienopyrimidine compounds
|
FR2988722B1
(fr)
*
|
2012-04-03 |
2014-05-09 |
Sanofi Sa |
Nouveaux derives de thienopyrimidines, leurs procedes de preparation et leurs utilisations therapeutiques
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
CN103360407B
(zh)
*
|
2012-04-10 |
2016-06-22 |
上海希迈医药科技有限公司 |
一种噻吩并嘧啶类衍生物、其制备方法及其在医药上的应用
|
CN103664991B
(zh)
*
|
2012-09-19 |
2016-12-28 |
中国科学院福建物质结构研究所 |
噻吩[2,3‑d]嘧啶衍生物、其制备方法及其用途
|
ES2644758T3
(es)
|
2012-10-16 |
2017-11-30 |
Tolero Pharmaceuticals, Inc. |
Moduladores de PKM2 y métodos para su uso
|
US9260426B2
(en)
|
2012-12-14 |
2016-02-16 |
Arrien Pharmaceuticals Llc |
Substituted 1H-pyrrolo [2, 3-b] pyridine and 1H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors
|
MX369175B
(es)
|
2013-02-25 |
2019-10-30 |
Genentech Inc |
Métodos para detectar mutantes de akt resistentes a fármacos.
|
AU2014236820B2
(en)
|
2013-03-14 |
2018-08-02 |
Sumitomo Pharma Oncology, Inc. |
JAK2 and ALK2 inhibitors and methods for their use
|
US9206188B2
(en)
|
2013-04-18 |
2015-12-08 |
Arrien Pharmaceuticals Llc |
Substituted pyrrolo[2,3-b]pyridines as ITK and JAK inhibitors
|
AR096654A1
(es)
*
|
2013-06-20 |
2016-01-27 |
Ab Science |
Derivados de benzimidazol como inhibidores selectivos de proteína quinasa
|
JP6946000B2
(ja)
|
2013-10-04 |
2021-10-06 |
アプトース バイオサイエンシーズ, インコーポレイテッド |
がんの治療用組成物及び方法
|
UA115388C2
(uk)
|
2013-11-21 |
2017-10-25 |
Пфайзер Інк. |
2,6-заміщені пуринові похідні та їх застосування в лікуванні проліферативних захворювань
|
PT3126521T
(pt)
|
2014-04-04 |
2019-06-27 |
Crown Bioscience Inc Taicang |
Gene de fusão hnf4g-rspo2
|
WO2015155624A1
(en)
|
2014-04-10 |
2015-10-15 |
Pfizer Inc. |
Dihydropyrrolopyrimidine derivatives
|
AP2016009530A0
(en)
|
2014-04-30 |
2016-10-31 |
Pfizer |
Cycloalkyl-linked diheterocycle derivatives
|
WO2016001789A1
(en)
|
2014-06-30 |
2016-01-07 |
Pfizer Inc. |
Pyrimidine derivatives as pi3k inhibitors for use in the treatment of cancer
|
KR20170031097A
(ko)
*
|
2014-07-16 |
2017-03-20 |
노보겐 리미티드 |
항암제로서 작용화되고 치환된 인돌
|
WO2016019280A1
(en)
|
2014-07-31 |
2016-02-04 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Human monoclonal antibodies against epha4 and their use
|
WO2016097918A1
(en)
|
2014-12-18 |
2016-06-23 |
Pfizer Inc. |
Pyrimidine and triazine derivatives and their use as axl inhibitors
|
BR112017022666A8
(pt)
|
2015-04-20 |
2022-10-18 |
Tolero Pharmaceuticals Inc |
Preparando resposta à alvocidib por perfilamento mitocondrial
|
US10011629B2
(en)
|
2015-05-01 |
2018-07-03 |
Cocrystal Pharma, Inc. |
Nucleoside analogs for treatment of the flaviviridae family of viruses and cancer
|
CN111349118B
(zh)
|
2015-05-18 |
2023-08-22 |
住友制药肿瘤公司 |
具有增加的生物利用度的阿伏西地前药
|
WO2017009751A1
(en)
|
2015-07-15 |
2017-01-19 |
Pfizer Inc. |
Pyrimidine derivatives
|
MX2018001289A
(es)
|
2015-08-03 |
2018-04-30 |
Tolero Pharmaceuticals Inc |
Terapias de combinacion para el tratamiento del cancer.
|
CN108601752A
(zh)
|
2015-12-03 |
2018-09-28 |
安吉奥斯医药品有限公司 |
用于治疗mtap缺失型癌症的mat2a抑制剂
|
JP7114076B2
(ja)
|
2015-12-22 |
2022-08-08 |
シャイ・セラピューティクス・エルエルシー |
がん及び炎症性疾患の処置のための化合物
|
CA3224365A1
(en)
*
|
2016-03-11 |
2017-09-14 |
Ac Immune Sa |
Bicyclic compounds for diagnosis and therapy of alpha-synuclein associated disorders
|
CN107652273B
(zh)
*
|
2016-07-26 |
2020-05-01 |
沈阳药科大学 |
嘧啶类衍生物及其制备方法和应用
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
CA3047557A1
(en)
|
2016-12-19 |
2018-06-28 |
Tolero Pharmaceuticals, Inc. |
Profiling peptides and methods for sensitivity profiling
|
AU2018288841B2
(en)
|
2017-06-21 |
2022-09-29 |
SHY Therapeutics LLC |
Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, Rasopathies, and fibrotic disease
|
US11497756B2
(en)
|
2017-09-12 |
2022-11-15 |
Sumitomo Pharma Oncology, Inc. |
Treatment regimen for cancers that are insensitive to BCL-2 inhibitors using the MCL-1 inhibitor alvocidib
|
US20200237766A1
(en)
|
2017-10-13 |
2020-07-30 |
Tolero Pharmaceuticals, Inc. |
Pkm2 activators in combination with reactive oxygen species for treatment of cancer
|
WO2020023910A1
(en)
|
2018-07-26 |
2020-01-30 |
Tolero Pharmaceuticals, Inc. |
Methods for treating diseases associated with abnormal acvr1 expression and acvr1 inhibitors for use in the same
|
WO2020117988A1
(en)
|
2018-12-04 |
2020-06-11 |
Tolero Pharmaceuticals, Inc. |
Cdk9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
|
JP7458406B2
(ja)
|
2018-12-21 |
2024-03-29 |
セルジーン コーポレーション |
Ripk2のチエノピリジン阻害剤
|
EP3924351A4
(en)
|
2019-02-12 |
2022-12-21 |
Sumitomo Pharma Oncology, Inc. |
FORMULATIONS COMPRISING HETEROCYCLIC PROTEIN KINASE INHIBITORS
|
EP3929185A4
(en)
*
|
2019-02-19 |
2023-02-15 |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
CONDENSED CYCLIC COMPOUND CONTAINING NITROGEN, METHOD FOR PREPARATION AND USE
|
CN113767100A
(zh)
*
|
2019-03-01 |
2021-12-07 |
锐新医药公司 |
双环杂芳基化合物及其用途
|
US11793802B2
(en)
|
2019-03-20 |
2023-10-24 |
Sumitomo Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (AML) with venetoclax failure
|
KR20210141621A
(ko)
|
2019-03-22 |
2021-11-23 |
스미토모 다이니폰 파마 온콜로지, 인크. |
Pkm2 조정제를 포함하는 조성물 및 그를 사용한 치료 방법
|
CN114269753B
(zh)
*
|
2019-09-29 |
2024-03-05 |
四川科伦博泰生物医药股份有限公司 |
一种含氮并环类化合物,包含其的药物组合物,其制备方法及其用途
|
IL293764A
(en)
*
|
2019-12-12 |
2022-08-01 |
Ptc Therapeutics Inc |
Compounds for the treatment of familial dysautonomia
|
WO2021155006A1
(en)
|
2020-01-31 |
2021-08-05 |
Les Laboratoires Servier Sas |
Inhibitors of cyclin-dependent kinases and uses thereof
|
CN115746017B
(zh)
*
|
2022-11-30 |
2024-06-07 |
英维沃化工科技(广州)有限公司 |
一种噻吩并嘧啶类化合物及其制备方法和应用
|